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sodium 2mercaptoethanesulfonate

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Sodium 2-mercaptoethanesulfonateMitexan,美司那,美司钠,Uromitexan,Mesna,Mesnum,Mesnex
T141419767-45-4
Sodium 2-mercaptoethanesulfonate (Uromitexan) 是一种抗氧化剂,具有细胞保护作用。它可用于减轻由环磷酰胺引起的出血性膀胱炎。它广泛用作抗化学疗法毒性的全身保护剂。
  • ¥ 291
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TargetMol | Citations 客户已引用
2',3'-cGAMP sodium2'-3'-cyclic GMP-AMP sodium
T10065L2734858-36-5In house
2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) 是细胞天然免疫中第二信使,在 DNA 结合条件下由 cGAMP 合成酶 (cGAS) 催化形成。2',3'-cGAMP sodium 可与 STING 结合形成二聚体,诱导 IFN-β 及其他细胞因子的产生和表达。
  • ¥ 2980
现货
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TargetMol | Inhibitor Hot
Sodium 2-oxopropanoateSodium pyruvate,丙酮酸钠
T7717113-24-6
Sodium 2-oxopropanoate (Sodium pyruvate) 是 pyruvate 的钠盐形式。pyruvate 是葡萄糖的三碳代谢物,是一种在糖酵解途径中产生的化合物,它是一种能够清除 ROS 的自由基清除剂。
  • ¥ 163
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2-Ketoglutaric acid SodiumOxoglutaric acid,AKG,2-oxoglutarate monobasic,LPHA-酮戊二酸钠,α-Ketoglutaric acid sodium salt
T492022202-68-2
2-Ketoglutaric acid Sodium (AKG) 是一种三羧酸循环的中间产物,它可以由谷氨酸通过谷氨酸脱氢酶氧化脱氨产生,也可以作为磷酸吡哆醛依赖的转氨化反应的产物(由支链氨基酸转氨酶介导),其中谷氨酸是常见的氨基供体。
  • ¥ 368
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sodium 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate
T50009L144254-93-3
sodium 3-amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxylate 是一种有机硫化合物。它已被用作研究含硫化合物对酶活性和代谢途径的影响的模型化合物,也被用于研究含硫化合物对细菌生长和基因表达调控的影响。
  • ¥ 178
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Sodium 3-methyl-2-oxobutanoate
T371533715-29-5
Sodium 3-methyl-2-oxobutanoate 是大肠杆菌中泛酸的前体。体外实验中可以增强Sodium 3-methyl-2-oxobutanoate和alpha-ketoisocaproic ac。
  • ¥ 561
5日内发货
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Sp-2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodiumSp-dCTP-α-S
T83828
Sp-2'-Deoxycytidine-5'-O-(1-thiotriphosphate) (Sp-dCTP-α-S) 是含硫核苷酸衍生物 dCTP-α-S 的异构体。它抑制解氧核苷酸三磷酸三磷酸水解酶 SAMHD1(Ki = 6.3 µM)。
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Rp-2'-Deoxyuridine-5'-O-(1-thiotriphosphate) sodiumRp-dUTP-α-S
T83833
Rp-2'-Deoxyuridine-5'-O-(1-thiotriphosphate) (Rp-dUTP-α-S) 是含硫核苷酸 dUTP-α-S 的同分异构体,也是嘌呤P2Y2受体的激动剂。在表达P2Y2受体的1321N1星形胶质瘤细胞中,该化合物特异性诱导肌醇磷酸积累(EC50 = 12.5 µM),相较于表达P2Y4的1321N1细胞,在10 µM浓度下效果更显著。
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Sodium 2-aminoacetate
T654366000-44-8
Sodium 2-aminoacetate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65436,CAS号为 6000-44-8。
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5日内发货
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Sodium 2-((hydroxymethyl)amino)acetate
T65335
Sodium 2-((hydroxymethyl)amino)acetate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T65335。
  • ¥ 158
5日内发货
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Sodium 2-chloro-2,2-difluoroacetate
T668991895-39-2
Sodium 2-chloro-2,2-difluoroacetate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66899,CAS号为 1895-39-2。
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5日内发货
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Adenosine 2',5'-diphosphate sodium
T39025154146-84-6
Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist with non-selective antagonism at recombinant and human platelet P2X1 receptors.
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4-methyl-2-Oxovalerate (sodium salt)
T357274502-00-5
4-methyl-2-Oxovalerate is an immediate precursor and metabolite of L-leucine. It is a precursor leading to the synthesis of 2-methylpropyl glucosinolate, via L-leucine, in plants. 4-methyl-2-Oxovalerate is one of several plasma metabolites found to differ significantly between type 2 diabetes and control subjects.
  • ¥ 647
35日内发货
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Sodium Channel inhibitor 2
T12951653573-60-5
Sodium Channel inhibitor 2 is a blocker of sodium channel.
  • ¥ 10600
6-8周
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DL-threo-2-methylisocitrate sodium
T19291
DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1 (ICL1). Using Michaelis-Menten nonlinear least squares fitting, the kcat value was determined to be 5.24 s-1, and the Km of the purified recombinant ICL1 for threonine-D(s)L(s)-isocitrate (ICA) was 188 μM.
  • ¥ 4250
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1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium
T63847326589-90-6
Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) 是一种改性 PS 产品,经由 NADPH 氧化酶激活及 Lyso-PS 信号转导后得到。Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium 能够利用巨噬细胞 G2A 功能,增强现有的受体 配体系统,进而解决中性粒细胞炎症。
  • ¥ 10600
6-8周
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Sodium 2-mercaptobenzothiazole
T718852492-26-4
Sodium 2-mercaptobenzothiazole is the sodium salt of mercaptobenzothiazole, and is used as a copper corrosion inhibitor.
  • ¥ 10600
6-8周
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2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium2′-fluoro-2′-deoxy ATP,AfTP,2'-fluoro dATP
T83830
2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate是ATP的一种氟代衍生物,ATP是细胞代谢必需的能量底物。它抑制E. coli RNA聚合酶(Ki = 200 µM)。
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Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) sodiumSp-dGTP-α-S
T83831
Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) 是一种含硫异构体,属于核苷酸三磷酸2'-脱氧鸟苷-5'-O-三磷酸(dGTP)。它通过抑制脱氧核苷酸三磷酸三磷酸水解酶SAMHD1 (Ki = 820 nM)发挥作用。
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2-Chloroadenosine-5'-O-diphosphate sodium2-chloro ADP
T8378582927-78-4
2-Chloroadenosine-5'-O-diphosphate是一种腺苷5'二磷酸(ADP)的衍生物。它在浓度依赖性的方式下,促进了人类富含血小板的血浆中的聚集,并抑制了由前列腺素E2(PGE2)诱导的环磷酸腺苷(cAMP)的产生。2-Chloroadenosine-5'-O-diphosphate引起预收缩的孤立的豚鼠taenia coli条带放松(pD2 = 6.74),降低大鼠的动脉血压。此外,它还抑制了热休克蛋白70(Hsp70)家族成员mortalin的ATP酶活性(人类酶的表观Ki = 45.05 µM)。
  • ¥ 4910
35日内发货
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1-Stearoyl-2-hydroxy-sn-glycero-3-PG sodium1-Stearoyl-2-hydroxy-sn-glycero-3-phosphoglycerol,18:0 Lyso-PG​,1-Stearoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol)
T85306326495-23-2
1-Stearoyl-2-hydroxy-sn-glycero-3-PG, a lysophospholipid characterized by the presence of stearic acid (18:0) at the sn-1 position, finds application in the creation of micelles, liposomes, and various artificial membranes, including those utilized in lipid-based drug delivery systems.
  • 询价
8-10周
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Sodium ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl diphosphate
T652179652-27-6
Sodium ((2R,3S,4R,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl diphosphate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T65217。
  • 询价
5日内发货
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Sodium 2-hydroxypropanoate
T65437
Sodium 2-hydroxypropanoate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T65437。
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5日内发货
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2',3'-cUMP sodiumUridine-2', 3'-cyclic monophosphate sodium salt
TN796215718-50-0
2',3'-cUMP sodium (Uridine-2', 3'-cyclic monophosphate sodium salt) 作为一种磷酸二对硝基苯基水解的竞争性抑制剂,具有明显的生物化学功能。
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Fumarate hydratase-IN-2 sodium salt
T113362070009-45-7
Fumarate hydratase-IN-2 sodium salt (compound 3) 是一种具有细胞渗透性和竞争性的富马酸水合酶(fumarate hydratase)抑制剂 (Ki=4.5 μM),具有营养依赖性细胞毒性。
  • ¥ 9870
10-14周
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2-Mercaptopyridine N-oxide sodium
T667763811-73-2
2-Mercaptopyridine N-oxide sodium 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66776,CAS号为 3811-73-2。
  • ¥ 328
5日内发货
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2'-O-Methylguanosine-5'-O-triphosphate sodium2'-methyl GTP,2'-O-methyl GTP
T83819
2’-O-甲基鸟苷-5'-O-三磷酸(2’-methyl GTP)作为丙肝病毒(HCV)非结构蛋白5B(NS5B;IC50 = 3.5 µM)的抑制剂,同时是前药IDX184的活性代谢产物,通过2’-methylguanosine中间体生成。在50 µM浓度下,2’-methyl GTP还能促进微管蛋白聚合。患有肝细胞癌的患者体内2’-methyl GTP水平,相比于邻近正常组织有所下降。
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2'-O-MB-cGMP sodium2′-O-Monobutyryl-cGMP sodium
T8879058329-72-9
2'-O-MB-cGMP sodium,全称2′-O-Monobutyryl-cGMP sodium,是环状 GMP 特异性磷酸二酯酶的抑制剂,其I50值达到35 µM。这种化合物可以抑制依赖于Ca2+的,以cAMP或cGMP作为底物的磷酸二酯酶的水解活性。
  • 询价
10-14周
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Sodium 2'-(dicyclohexylphosphino)-2,6-dimethoxy-[1,1'-biphenyl]-3-sulfonate
T67430
Sodium 2'-(dicyclohexylphosphino)-2,6-dimethoxy-[1,1'-biphenyl]-3-sulfonate 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67430。
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5日内发货
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1-Oleoyl-2-hydroxy-sn-glycero-3-PG sodium1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol),1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoglycerol,​18:1 Lyso-PG
T85302326495-24-3
1-Oleoyl-2-hydroxy-sn-glycero-3-PG (sodium salt), a lysophospholipid with oleic acid (18:1) at the sn-1 position, finds application in creating micelles, liposomes, and various artificial membranes, notably in lipid-based drug delivery systems.
  • 询价
8-10周
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2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)
T37106
2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis.1dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications.3,4dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations in the gene for adenosine deaminase, the enzyme that catalyzes the deamination of adenosine and deoxyadenosine.5 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Key steps in nucleotide biosynthesis are regulated by feedback inhibitionBiochemistry(2002) 2.Berg, J.M., Tymoczko, J.L., and Stryer, L.DNA is replicated by polymerases that take instructions from templatesBiochemistry(2002) 3.Cadwell, R.C., and Joyce, G.F.Randomization of genes by PCR mutagenesisPCR Methods Appl.2(1)28-33(1992) 4.Steffens, D.L., Jang, G.Y., Sutter, S.L., et al.An infrared fluorescent dATP for labeling DNAGenome Res.5(4)393-399(1995) 5.Flinn, A.M., and Gennery, A.R.Adenosine deaminase deficiency: A reviewOrphanet J. Rare Dis.13(1)65(2018)
  • ¥ 716
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2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
T35652146877-98-7
2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.
  • ¥ 857
35日内发货
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Cytidine-5'-O-(2-thiodiphosphate) sodiumCDP-β-S
T83816
Cytidine-5’-O-(2-thiodiphosphate) (CDP-β-S) 是一种不可水解的CDP衍生物,具有抗氧化活性。在Trolox等效吸收能力(TEAC)测定中,该化合物在5至20 µM的浓度范围内清除自由基。
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2-Chloroadenosine 5-triphosphate sodium2-chloro ATP
T84928301334-89-4
2-Chloroadenosine 5-triphosphate (2-chloro ATP), an analog of ATP and adenine nucleotide, functions as an antagonist of the purinergic P2Y1 receptor, inhibiting ADP-induced intracellular calcium mobilization in Jurkat cells with a Ki value of 2.3 µM. Additionally, 2-chloro ATP acts as an agonist of purinergic P2X receptors, demonstrated by inducing inward currents in HEK293 cells expressing either human bladder smooth muscle or rat PC12 receptor forms, with EC50 values of 0.5 and 2.5 µM, respectively. It also triggers relaxation in precontracted isolated guinea pig taenia caeci strips in a concentration-dependent fashion. Furthermore, 2-chloro ATP has been employed in research to investigate the substrate specificity of cyclic nucleotide-dependent protein kinases, including protein kinase A (PKA) and PKG.
  • 询价
8-10周
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