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TMPH-00845
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HSD17B13 Protein, Human, Recombinant (His & Myc)
Hepatic retinol/retinal dehydrogenase,Short cha...
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Human
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P. pastoris (Yeast)
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HSD17B13 Protein, Human, Recombinant (His & Myc) is expressed in yeast with N-6xHis and C-Myc tag. The predicted molecular weight is 34.8 kDa and the accession number is Q7Z5P4. |
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TMPH-02716
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HADH Protein, Mouse, Recombinant (His & SUMO)
Short-chain 3-hydroxyacyl-CoA dehydrogenas...
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Mouse
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E. coli
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Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10). Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion. HADH Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted... |
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TMPH-00405
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Acyl-CoA dehydrogenase Protein, Clostridium acetobutylicum, Recombinant (His & Myc)
Acyl-CoA dehydrogenase, short-chain specif...
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Clostridium acetobutylicum
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E. coli
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Acyl-CoA dehydrogenase Protein, Clostridium acetobutylicum, Recombinant (His & Myc) is expressed in E. coli. |
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TMPH-03232
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HSD17B13 Protein, Rat, Recombinant (His)
Hsd17b13,17-beta-hydroxysteroid dehydrogenase 13,Hepatic ret...
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Rat
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Baculovirus Insect Cells
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N/A. HSD17B13 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with N-6xHis tag. The predicted molecular weight is 32.4 kDa and the accession number is Q5M875. |
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TMPH-03233
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HSD17B13 Protein, Rat, Recombinant (E. coli, His)
Short-chain dehydrogenase/reductase 9,Hsd1...
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Rat
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E. coli
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N/A. HSD17B13 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 37.4 kDa and the accession number is Q5M875. |
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TMPJ-00754
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CRYAA Protein, Human, Recombinant (His)
Heat Shock Protein Beta-4,CRYA1,α-Crystallin A Chain
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Human
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E. coli
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Alpha-Crystallin A Chain (CRYAA) belongs to the small heat shock protein (HSP20) family and can be induced by heat shock. The expression of CRYAA is preferentially restricted to the lens cell. CRYAA may contribute to the transparency and refractive index of the lens. CRYAA has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Two additional functions of CRYAA are an autokinase activity and participation in the intracellular architecture. |
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TMPH-01303
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HSD17B11 Protein, Human, Recombinant (His & Myc)
Estradiol 17-beta-dehydrogenase 11,HSD17B11,Retinal shor...
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Human
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E. coli
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Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. HSD17B11 Prot... |
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TMPH-00843
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HSD11B1 Protein, Human, Recombinant (His & SUMO)
7-oxosteroid reductase,11-beta-hydroxysteroid dehydrogenase ...
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Human
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E. coli
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Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol. HSD11B1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 45.5 kDa and the accession number is P28845. |
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TMPH-00876
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ACSS1 Protein, Human, Recombinant (E. coli, His)
Acetate--CoA ligase 2,Acetyl-coenzyme A synthetase 2-like, m...
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Human
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E. coli
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Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions. Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient. ACSS1 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted... |
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TMPH-01302
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HSD17B1 Protein, Human, Recombinant (His & Myc)
Placental 17-beta-hydroxysteroid dehydrogenase,Short
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Human
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E. coli
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Favors the reduction of estrogens and androgens. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2). Also has 20-alpha-HSD activity. Uses preferentially NADH. HSD17B1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 42.3 kDa and the accession number is P14061. |
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TMPH-00844
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HSD11B2 Protein, Human, Recombinant (His)
HSD11B2,11-beta-hydroxysteroid dehydrogenase type 2,Shor...
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Human
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P. pastoris (Yeast)
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Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids. HSD11B2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 46.1 kDa and the accession number is P80365. |
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TMPH-02488
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ACSS2 Protein, Mouse, Recombinant (His)
Propionate--CoA ligase,AceCS1,Acyl-activating enzyme,Acetyl-...
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Mouse
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E. coli
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Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate but can also utilize propionate with a much lower affinity. ACSS2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 82.9 kDa and the accession number is Q9QXG4. |
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TMPH-00877
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ACSS1 Protein, Human, Recombinant (His)
Acetate--CoA ligase 2,KIAA1846,Acetyl-coenzyme A synthetase ...
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Human
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P. pastoris (Yeast)
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Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Acetate is the preferred substrate. Can also utilize propionate with a much lower affinity. Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions. Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient. ACSS1 Protein, Human, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 73.6 kD... |
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TMPJ-01111
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TSTA3 Protein, Human, Recombinant (His)
GDP-L-Fucose Synthase,Short-Chain Dehydrog...
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Human
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E. coli
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GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II. |
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TMPH-01410
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GPR84 Protein, Human, Recombinant (hFc)
G-protein coupled receptor 84,GPR84,Inflammation-related G-p...
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Human
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P. pastoris (Yeast)
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Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system. GPR84 Protein, Human, Recom... |
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TMPH-02464
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AIIM Protein, Microbacterium testaceum, Recombinant (His & SUMO)
AHL-lactonase,N-acyl homoserine lactonase
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Microbacterium testaceum
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E. coli
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Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3. Has slight activity towards L-homoserine lactone, and no activity towards gamma-butyrolactone. AIIM Protein, Microbacterium testaceum, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.3 kDa and the accession number is C6L862. |
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TMPH-00178
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AiiA Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc)
N-acyl homoserine lactonase AiiA,AHL-lactonase AiiA
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Bacillus thuringiensis subsp. kurstaki
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E. coli
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Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long-chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL. AiiA Protein, Bacillus thuringiensis subsp., Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 35.7 kDa and the accession number is P0CJ63. |
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TMPH-00711
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BioH Protein, E. coli, Recombinant (His & Myc)
bioB,Carboxylesterase BioH,Biotin synthesis protein BioH,Pim...
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E. coli
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E. coli
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The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. E.coli employs a methylation and demethylation strategy to allow elongation of a temporarily disguised malonate moiety to a pimelate moiety by the fatty acid synthetic enzymes. BioH shows a preference for short chain fatty acid esters (acyl c... |
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TMPJ-00921
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COL8A1 Protein, Human, Recombinant (His)
Vastatin,Endothelial Collagen,Collagen Alpha-1(VIII) Cha...
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Human
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HEK293 Cells
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Collagen alpha-1(VIII) chain, also known as endothelial collagen, C3orf7 and COL8A1, can be cleaved into vastatin chain. COL8A1 is a short chain collagen and a major component of the basement membrane of the corneal endothelium. COL8A1 forms homotrimers, or heterotrimers in association with alpha 2(VIII) type collagens. Four homotrimers can form a tetrhedron stabilized by central interacting C-terminal NC1 trimers. COL8A1 contains one C1q domain and is primarily expressed in the subendothelium o... |
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TMPJ-01075
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BDH1 Protein, Human, Recombinant (His)
D-β-Hydroxybutyrate Dehydrogenase Mitochondrial,D-Beta-Hydro...
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Human
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E. coli
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D-Beta-Hydroxybutyrate Dehydrogenase Mitochondrial (BDH) is a member of the short-chain dehydrogenases/reductases (SDR) family. BDH is localized in the mitochondrion matrix. BDH forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific necessity for phosphatidylcholine for optimal enzymatic activity. BDH catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the 2 main ketone bodies formed during fatty acid catabolism. |
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TMPJ-00463
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BDH2 Protein, Human, Recombinant (His)
Oxidoreductase UCPA,Dehydrogenase/Reductase SDR Family Membe...
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Human
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E. coli
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3-Hydroxybutyrate Dehydrogenase Type 2 belongs to the short-chain dehydrogenases/reductases (SDR) family. 3-Hydroxybutyrate Dehydrogenase Type 2 may play an important role in the peripheral utilization of 3-hydroxybutyrate. The cytoplasmic localization with its high ratio of oxidized NAD+, the NAD+ dependence and the kinetic parameters of 3-Hydroxybutyrate Dehydrogenase Type 2 make it suitable to conbert high levels of circulating 3-hydroxybutyrate into acetoacetate. |
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TMPH-00534
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Gelatinase Protein, Enterococcus faecalis, Recombinant (His & SUMO)
Gelatinase,gelE,Coccolysin
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Enterococcus faecalis
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E. coli
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Metalloprotease capable of the hydrolysis of insoluble hydrophobic substrates. Hydrolyzes azocoll and gelatin and, at a lower rate, soluble and insoluble collagens. Does not cleave short synthetic peptides. Preferentially hydrolyzes the 24-Phe-|-Phe-25 bond in the insulin B-chain, followed by the 5-His-|-Leu-6 bond. Inactivates endothelin-1, primarily by cleavage of the 5-Ser-|-Leu-6 and 16-His-|-Leu-17 bonds. Hydrolyzes the alpha chain of C3 to generate a C3b-like protein. Inhibits complement-m... |
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TMPJ-00475
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Kallikrein 1/KLK1 Protein, Human, Recombinant (aa 19-262, His)
Tissue Kallikrein,Kidney/Pancreas/Salivary Gland Kallikrein,...
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Human
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HEK293 Cells
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Kallikrein-1 (KLK1) is a member of human tissue Kallikrein family. Human KLK1 precursor contains a singal peptide (residues 1 to 18), a short pro peptide (residues 19 to 24) and a mature chain (residues 25 to 262). The function of KLK1 is to cleave Kininogen in order to release the vasoactive Kinin peptide (Lysyl-Bradykinin or Bradykinin). The Kinin peptide controls blood pressure reduction, vasodilation, smooth muscle relaxation and contraction, pain induction and inflammation. KLK1 also plays ... |
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TMPY-03867
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CBR3 Protein, Human, Recombinant (His)
SDR21C2,carbonyl reductase 3,hCBR3,HEL-S-25
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Human
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E. coli
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CBR3, also known as hCBR3, belongs to the short-chain dehydrogenases/reductases (SDR) family. CBR3 is expressed in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis. It is a monomeric NADPH-dependent oxidoreductase and is closely linked to another carbonyl reductase gene – CBR1. CBR3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It has lo... |
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TMPJ-00797
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LDHB Protein, Human, Recombinant (His)
LDH-B,Renal Carcinoma Antigen NY-REN-46,LDH-H,LDH Heart Subu...
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Human
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E. coli
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L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family that consists of three members, LDH-A, LDH-B and LDH-C; members of this family function as powerful markers for germ cell tumors. LDH-B is an oxidoreductase that catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. It converts pyruvate to lactate when oxygen is absent or in short supply and it performs the reverse reaction during the Cori cycle in the liver.... |
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TMPY-03460
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DCXR Protein, Human, Recombinant (His)
XR,P34H,HCR2,HCRII,PNTSU,SDR20C1,DCR,dicarbonyl/L-xylulose r...
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Human
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E. coli
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DCXR, also known as HCR2, belongs to the short-chain dehydrogenases/reductases (SDR) family. It is highly expressed in kidney, liver and epididymis. In the epididymis, DCXR is mainly expressed in the proximal and distal sections of the corpus region. HCR2 is weakly or not expressed in brain, lung, heart, spleen and testis. DCXR catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. DCXR participates in the uronate cycle of... |
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TMPJ-00813
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QDPR Protein, Human, Recombinant (His)
Dihydropteridine Reductase,QDPR,DHPR,HDHPR,Quinoid Dihydropt...
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Human
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HEK293 Cells
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Dihydropteridine reductase, also known as HDHPR and Quinoid dihydropteridine reductase, QDPR and DHPR, belongs to the short-chain dehydrogenases/reductases (SDR) family. QDPR exists as a homodimer. QDPR is part of the pathway that recycles a substance called tetrahydrobiopterin, also known as BH4 and tryptophan hydroxylases. The regeneration of this substance is critical for the proper processing of several other amino acids in the body. Tetrahydrobiopterin also helps produce certain chemicals i... |
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TMPH-01624
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GBA Protein, Human, Recombinant
Lysosomal glycosylceramidase,Acid beta-glucosidase,Alglucera...
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Human
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E. coli
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Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction tha... |
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TMPH-01623
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GBA Protein, Human, Recombinant (His & Myc & SUMO)
Lysosomal acid glucosylceramidase,GBA1,Lysosomal galactosylc...
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Human
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E. coli
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Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction tha... |
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TMPJ-00812
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HBQ1 Protein, Human, Recombinant (His)
Hemoglobin subunit θ-1,Hemoglobin subunit theta-1,Hemoglobin...
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Human
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E. coli
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Hemoglobin subunit theta-1 is a protein that in humans is encoded by the HBQ1 gene. Theta-globin mRNA is originally found in human fetal erythroid tissue but not in adult erythroid or other nonerythroid tissue. Theta-1 is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. Research supports a transcriptionally active role for the gene and a functional role for the peptide in specific cells, possibly those of early erythroid tissue. Hemoglobin ... |
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