Atorvastatin acetonide tert-butyl ester, a valuable pharmaceutical intermediate, is used in preparing Atorvastatin salts, an HMG-CoA reductase inhibitor.
Triptorelin, a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2), is a gonadotropin-releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts. By causing constant stimulation of the pituitary, it decreases pituitary secretion of gonadotropins luteinizing hormone (LH) and follicle stimulating hormone (FSH). Like other GnRH agonists, triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer, precocious puberty, estrogen-dependent conditions (such as endometriosis or uterine fibroids), and in assisted reproduction. It is also used as therapy for gender identity disorder.
Decamethyltetrasiloxane, a non-cyclic silicone oligomer, is used in the methylation of mercury(II) salts. It is transformed by a specific microflora. In the natural environment, it is degraded by mechanisms similar to other organic compounds.
Δ2-cisEicosenoic acid, an α,β-unsaturated fatty acid extracted and purified from fresh water clams, alongside its related compound 2-octadecenoic acid, which improves liver function and decreases blood sugar in streptozocin-induced diabetic rats, and its salts, holds potential medicinal value for treating diabetes and enhancing lipid metabolism.
Dequalinium is a quaternary ammonium cation and bolaamphiphile commonly available as the dichloride salt. The bromide, iodide, acetate, and undecenoate salts are known as well.
Benzylpenicillin is a penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci.
Δ2-transEicosenoic acid, an α,β-unsaturated fatty acid, emerges as a by-product during the synthesis of Δ2-ciseicosenoic acid, which along with its salts, shows promise in diabetes treatment and lipid metabolism enhancement. Additionally, the compound 2-octadecenoic acid is recognized for its ability to enhance liver function and reduce blood sugar levels in streptozocin-induced diabetic rats.