首页工具

登录

搜索结果

Search Results for " renal diseases "

Targets Recommended: Tyrosinase

10

抑制剂 & 化合物

2

天然产物

1

化合物库

3

重组蛋白

1

同位素标记化合物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L8700	铁死亡化合物库		779 compounds
	779 种与铁死亡通路相关的化合物，可用于高通量和高内涵筛选；

化合物库

铁死亡化合物库

Cat.No: L8700

Compounds: 779

Cat. No.	Product Name	Target	Signaling Pathways
T7714	Temocapil	Tyrosinase	Proteases/Proteasome
	Temocapil 是一种酪氨酸激酶抑制剂。
T6698	Temocapril hydrochloride CS-622 HCl,Acecol,Temocapril HCl,CS-622,盐酸替莫普利	RAAS	Endocrinology/Hormones
	Temocapril hydrochloride (CS-622 HCl) 是血管紧张素转化酶 (ACE) 抑制剂。Temocapril HCl 能够用于充血性心力衰竭、急性心肌梗死、高血压、胰岛素抵抗和肾脏疾病的研究。
T50000	2-Iodohippuric Acid	Others	Others
	2-Iodohippuric Acid 可以用来测量肾脏的清除率用于肾功能研究，也用于某些疾病的诊断，如肝病和肾病。此外，它还用于某些药物的合成。
T1182	Levocarnitine propionate hydrochloride Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,丙酰左旋肉碱盐酸盐,ST-261,丙酰肉碱盐酸盐	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Levocarnitine propionate hydrochloride (ST-261) 可用于肾功能恶化，充血性心脏衰竭，间歇性跛行等疾病的研究。
T8366	Mitochonic acid 5 MA-5	Mitochondrial Metabolism	Metabolism
	Mitochonic acid 5 (MA-5) 能够调节线粒体 ATP 合成，可与线粒体结合，并改善肾小管和心肌细胞损伤。
T16808	Runcaciguat	Others; Guanylate cyclase	GPCR/G Protein; Others
	Runcaciguat 是一种可溶性鸟苷酸环化酶刺激剂。 Runcaciguat 与特异性部分腺苷 A1 受体激动剂相结合，可用于心血管和肾脏疾病的研究。
T11412	IPN60090 GLS1-IN-1	Others; transporter	Metabolism; Others
	IPN60090是一种新型、强效、口服生物利用度高的肾型谷氨酰胺酶（GLS1）特异性抑制剂，对GLS1的IC50值为31 nM。IPN60090 具有潜在的抗癌和免疫刺激/免疫调节活性，可选择性地靶向、结合并抑制人谷氨酰胺酶，可用于研究 GLS1 介导的疾病。
T39611	Enuvaptan Enuvaptan,BAY-2327949	Others	Others
	Enuvaptan is a vasopressin receptor antagonist and has the potential for research into renal and cardiovascular diseases.
T71450	Ilacirnon sodium	Others	Others
	Ilacirnon sodium is a potent CCR2 antagonist that may be useful in the treatment of renal diseases including Focal Segmental Glomerulosclerosis and Diabetic Nephropathy.
T76762	Tabalumab
	Tabalumab (LY2127399) 是一种人源化的抗BAFF(B 细胞激活因子) 单克隆抗体 (IgG4 型)，对膜结合和可溶性BAFF 具有中和活性。Tabalumab 可用于自身免疫性疾病，如类风湿性关节炎、肾衰竭和系统性红斑狼疮的研究。

化合物

Cat.No: T7714

Target: Tyrosinase

Temocapril hydrochloride

Cat.No: T6698

Synonym: CS-622 HCl,Acecol,Temocapril HCl,CS-622,盐酸替莫普利

Target: RAAS

2-Iodohippuric Acid

Cat.No: T50000

Target: Others

Levocarnitine propionate hydrochloride

Cat.No: T1182

Synonym: Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,丙酰左旋肉碱盐酸盐,ST-261,丙酰肉碱盐酸盐

Target: Histamine Receptor

Mitochonic acid 5

Cat.No: T8366

Synonym: MA-5

Target: Mitochondrial Metabolism

Cat.No: T16808

Target: Others, Guanylate cyclase

Cat.No: T11412

Synonym: GLS1-IN-1

Target: Others, transporter

Cat.No: T39611

Synonym: Enuvaptan,BAY-2327949

Target: Others

Ilacirnon sodium

Cat.No: T71450

Target: Others

Cat.No: T76762

Cat. No.	Product Name	Target	Signaling Pathways
T8053	N-Acetyl-L-arginine N-Α-乙酰-L-精氨酸,Ac-Arg-OH	Endogenous Metabolite	Metabolism
	N-Acetyl-L-arginine (Ac-Arg-OH) 是一种胍基诺化合物，被发现存在于血液渗析性肾不足儿童患者血清中的。
TN3753	Dalbergioidin	Tyrosinase; ROS; Akt; PI3K; TGF-beta/Smad	Cytoskeletal Signaling; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
	Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator organism. Dalbergioidin protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway, suggests that it may be useful in bone metabolism diseases, particularly osteoporosis. Dalbergioidin also ameliorates doxorubicin-induced ...

天然产物

N-Acetyl-L-arginine

Cat.No: T8053

Synonym: N-Α-乙酰-L-精氨酸,Ac-Arg-OH

Target: Endogenous Metabolite

Cat.No: TN3753

Target: Tyrosinase, ROS, Akt, PI3K, TGF-beta/Smad

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04483	IRAK4 Protein, Human, Recombinant (His) IPD1,NY-REN-64,REN64,interleukin-1 receptor-associated kinas...	Human	Baculovirus Insect Cells
	Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ...
TMPY-00261	Meprin beta Protein, Human, Recombinant (His) meprin A, β,Meprin β,meprin A, beta	Human	HEK293 Cells
	MEP1B (Meprin A Subunit Beta) is a Protein Coding gene. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in the kidney and intestine. Meprins are cell membrane, oligomeric metalloendopeptidases composed of two distinct but evolutionarily related subunits, alpha, and beta. MEP1A is mapped to the short arm of chromosome 6 by the use of radiation and som...
TMPJ-00332	tPA Protein, Human, Recombinant (His) TPA,T-PA,t-plasminogen activator,Tissue plasminogen activato...	Human	HEK293 Cells
	Tissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space. PLAT contains five domains: EGF-like domain, fibronectin type-I domain, 2 kringle domains and peptidase S1 domain. It belongs to the peptidase S1 family. The main function of this protein is to convert plasminogen into biologically active plasmin. As a protease, PLAT plays a crucial role in regulating blood fibrinolysis, maintaining the homeostasis of extracellular matrix and in modulating the post-tra...

重组蛋白

IRAK4 Protein, Human, Recombinant (His)

Cat.No: TMPY-04483

Species: Human

Expression System: Baculovirus Insect Cells

Meprin beta Protein, Human, Recombinant (His)

Cat.No: TMPY-00261

Species: Human

Expression System: HEK293 Cells

tPA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00332

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T70990	ADMA-d6
	NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA levels are increased concomitant with an increase in blood pressure in Da...

同位素标记化合物

Cat.No: T70990

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼