Propargyl-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable triethylene glycol linker with propargyl and N-hydroxysuccinimide functional groups. It is utilized in the synthesis of antibody-drug conjugates (ADCs)[1].
Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable linker consisting of a 1-unit polyethylene glycol (PEG) backbone, designed for use in the synthesis of antibody-drug conjugates (ADCs)[1].
N-(Azido-PEG3)-N-Biotin-PEG4-methylester is a polyethylene glycol (PEG) derivative used as a PROTAC linker for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].
Benzyl-PEG3-methylester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker commonly employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
Propargyl-PEG3-methylester is a propargyl polyethylene glycol (PEG) derivative that serves as a linker in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
Tris[[2-(tert-butoxycarbonyl)ethoxy]methyl]methylamine, a cleavable PEG ADC linker, is employed in the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker, specifically Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane, widely used in the synthesis of PROTACs[1].
DBCO-NHS ester 2 is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs). It is a Dibenzylcyclooctyne (DBCO) derivative specifically designed for application in copper-free click chemistry [1].
m-PEG4-CH2-methylester is a polyethylene glycol (PEG)- and Alkyl ester-based linker utilized in the fabrication of proteolysis targeting chimeras (PROTACs) [1].
Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate compound that combines a Thalidomide-based cereblon ligand and a linker, which is commonly utilized in PROTAC technology. This compound acts as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.
Propargyl-PEG5-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG2-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker. This specific linker is utilized in the synthesis of PROTACs, or proteolysis targeting chimeras [1].
Hydroxy-PEG2-C2-methylester is a polyethylene glycol (PEG)-based linker commonly employed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy3 is a polyethylene glycol (PEG)-based linker used for the synthesis of proteolysis targeting chimeras (PROTACs) [1].
(2-Pyridyldithio)-PEG4-propargyl is a polyethylene glycol (PEG)-based linker specifically designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].
N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methylester) is a polyethylene glycol (PEG) based linker, employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].