proinsulin c peptide (human)

Proinsulin C-peptide (human) is a 31-amino acid peptide that links the Proinsulin A and B chains, ensuring their proper folding, biological activity, and regulation of cellular functions.

Proinsulin C-peptide human acetate (Proinsulin C-peptide human acetate (33017-11-7 Free base)) 是一种由31个氨基酸残基组成的多肽，它连接胰岛素原的 A 链和 B 链以确保正确折叠，具有生物活性并调节细胞功能。

Human proinsulin, the single-chain peptide precursor of insulin, consists of the insulin A and B chains connected by the 31 amino acid C-peptide. Cleavage of proinsulin by proteolytic enzymes produces insulin and free C-peptide.

MOTS-c(Human) Acetate（1627580-64-6 free）是一种线粒体衍生肽。 它诱导 AMP 类似物 AICAR 的积累，增加 AMPK 的激活和其下游 GLUT4 的表达。它可诱导葡萄糖摄取并提高胰岛素敏感性。 它对调节肥胖、糖尿病、运动和长寿有重要意义。

C-Type Natriuretic Peptide (CNP) (1-22), human acetate 是一种利钠肽受体 B (NPR-B) 的激动剂，一种内皮衍生的松弛剂和生长抑制因子。 C-Type Natriuretic Peptide (CNP) (1-22), human acetate 抑制由组胺和 5-HT 或直接由毛喉素刺激的 cAMP 合成。

Protein Kinase C Peptide Substrate acetate(120253-69-2 free base) 以依赖于第二信使和特定衔接蛋白的方式靶向特定细胞间隔物，以响应激活 g 蛋白偶联受体、酪氨酸激酶受体或酪氨酸激酶偶联受体的细胞外信号。

Activated Protein C (390-404), human acetate (Activated Protein C ) 抑制 APC 抗凝活性。

c-Myc Peptide Trifluoroacetate (145646-22-6 free base) 是一种合成肽，对应于人类 c-myc 蛋白的 C 末端氨基酸 (410-419)，参与调控生长相关基因的转录。

Amyloid β Peptide (42-1)(human) acetate 是淀粉样蛋白 β 肽 (1-42) 的无活性形式。Amyloid β Peptide (42-1)(human) acetate 是由 42 个氨基酸组成的肽，其在阿尔茨海默病的发病机制中起关键作用。

GnRH Associated Peptide (GAP) (1-13), human Acetate 被发现是催乳素分泌的有效抑制剂并刺激促性腺激素的释放。用对应于 GAP 序列的肽进行主动免疫导致催乳素分泌大大增加。

C-MYC PEPTIDE EPITOPE TFA 是 c-myc 原癌基因的产物，是一种螺旋-环-螺旋亮氨酸拉链磷蛋白，可调节细胞增殖、细胞分化和凋亡中的基因转录。该肽是人类 c-myc 表位。

Gastrin-Releasing Peptide, human(TFA） (93755-85-2 free base) 是一种调节性人类肽，可引发胃泌素释放并调节胃酸分泌和肠道运动功能。支配胃G 细胞的迷走神经节后纤维释放GRP，刺激G 细胞释放胃泌素。

Peptide YY (PYY) (3-36), human (Peptide YY (3-36)) 是一种肠胃激素肽，可以激动Y2受体，具有降低食欲的功效。

C-Type Natriuretic Peptide (CNP) (1-22), human 是一种利钠肽受体 B (NPR-B) 激动剂，是一种 CNP 的 1-22 片段。它对生理激动剂组胺和 5-HT 刺激或直接由 Forskolin 刺激的 cAMP 合成具有抑制作用。其中CNP 是一种有效的、内皮衍生的松弛剂和生长抑制因子。

Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 是颗粒鸟苷酸环化酶的刺激剂，已被发现通过增加环鸟苷单磷酸的合成来保护分离的心肌细胞免受复氧诱导的高收缩。Atrial Natriuretic Peptide (ANP) (1-28), human, porcine Acetate 也有助于在反复运动期间刺激脂解，并在运动期间控制脂解。

Pegylated synthetic human c-peptide 保留与天然（即非聚乙二醇化）C 肽相当的生物活性，且延长了在血浆中的循环停留时间，适用于糖尿病性周围神经病变的研究。

Myelin Oligodendrocyte Glycoprotein (MOG) peptide 是 MOG 的一种内源性肽段截取，存在于髓鞘的细胞外表面。当与抗原血清型HLA-DR2结合时，MOG peptide 在通过中脑动脉阻塞（MCAO）诱导的缺血性中风模型中，能减少皮层和纹状体梗死体积，降低管-角转测试中的感觉运动障碍，增加对新奇气味的探索时间，以及增加雌性（但不是雄性）小鼠对笼伴侣发出的呼叫持续时间。

胃抑制肽1(GIP-1) (3-42)是肠促胰岛素激素GIP的一个肽段，同时也是GIP受体的拮抗剂。它通过血清二肽基肽酶4(DDP-4)从GIP中形成。GIP-1 (3-42) (100 nM)在减少BRIN-BD11胰腺细胞的胰岛素分泌方面起作用。在以25 nmol/kg剂量给药的ob/ob糖尿病小鼠模型中，它能增加血浆葡萄糖水平并降低血浆胰岛素水平。

(Leu31,Pro34)-Peptide YY (human) 是一种 Peptide YY 的衍生物，是一种有效的、选择性的 Y1激动剂，KD 为 1.0 nM。

Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM. In vivo, intracerebral injection of Aβ (25-35) (20 nmol) in rats induces lesions of neuronal and tissue loss. Aggregated Aβ (25-35) administered intracerebroventricularly to rats induces learning and memory impairments in the Y-maze, novel object recognition, and contextual fear conditioning tests.

Atrial natriuretic peptide (3-28) (human) 是由心房心肌细胞合成并分泌的肽类激素，主要在调节血压、体液平衡及电解质稳态方面发挥作用。

'(Leu31,Pro34)-Peptide YY (human)(TFA)' 为 '(Leu31,Pro34)-Peptide YY (human)' 的 TFA 盐形式，该化合物为 Peptide YY 的衍生物，兼具高效和选择性的 Y1 受体激动剂特性，其 KD 值为 1.0 nM。

Glucagon-like peptide 1 (1-37), human (TFA), is a highly potent agonist of the GLP-1 receptor and is a pancreatic hormone synthesized through post-translational processing of proglucagon.

Glucagon-like peptide 1 (1-37), human, is a highly potent agonist of the GLP-1 receptor and a pancreatic hormone synthesized through post-translational processing of proglucagon. Unlike truncated forms of GLP-1, it has no effect on food intake in rats.

CNP, a member of the natriuretic peptide family, was first identified in porcine brain and later found in other mammals as well as non-mammals. Processing of the CNP precursor gives rise to CNP-22 and its N-terminally elongated form, CNP-53. The CNPs shar

Prolactin Releasing Peptide (1-31), human is a high affinity GPR10 ligand that cause the release of the prolactin

c-Myc Peptide is a useful displacement of c-Myc-tagged fusion proteins bound to anti-c-Myc antibodies in immunoassays. The successful inhibition of antibody binding by c-Myc peptide demonstrates binding is specific. c-Myc peptide participates in the regul

Protein Kinase C Peptide Substrate targets specific cell spacers ina manner that is dependent on second messengers and specific adaptor proteins in response to extracellular signals that activate g protein-coupled receptors, tyrosine Kinase receptors, or

Relaxin C-peptide, as a synthetic 14-amino acid peptide found in human decidua & placenta, can represent a partial sequence of human relaxin connecting peptide.

MOTS-c(human) acetate 是一种线粒体衍生的肽，可诱导 AMP 类似物AICAR 的积累，增加AMPK 的激活及其下游GLUT4的表达。MOTS-c(human) acetate 可诱导葡萄糖摄取并改善胰岛素敏感性，对肥胖，糖尿病，运动和长寿的调节具有影响。

AcetylGastric Inhibitory Peptide(human) TFA 是一种葡萄糖依赖性胰岛素释放多肽的改性脂肪酸衍生物，具有增强的抗高血糖和促胰岛素作用。它主要用于糖尿病、胰岛素抵抗和肥胖的科研领域。

Klotho衍生肽1（KP1）(56-87)是从人类Klotho蛋白质中衍生的肽，具有扰乱TGF-β信号传导的作用。它与TGF-β受体类型1（TGFBR2）和TGF-β受体类型2（TGFBR2；Kds分别为1.41和14.6µM）结合。KP1（10 µg/ml）的预孵育抑制TGF-β在NRK-49F大鼠成纤维细胞中诱导的纤维连接蛋白和α-平滑肌肌动蛋白（α-SMA）水平的增加。在体内，KP1（每天1 mg/kg）选择性地定位于受损的肾脏，并减少血清肌酐和血尿素氮水平，这些是肾功能的标志物，同时也减少了小鼠单侧输尿管阻塞（UUO）和单侧缺血-再灌注损伤诱导的肾脏纤维化模型中的肾纤维化。

Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human 是一种被 C 端标记的生物素化 GLP-1(7-36) 酰胺。

Protein Kinase C γ Peptide，Protein Kinase Cγ 的肽片段，为显性共济失调的致病蛋白，能够负向调节隐性共济失调相关失联蛋白的核输入。

Atrial Natriuretic Peptide (1-28), human, porcine, Biotin-labeled, is one of three mammalian natriuretic peptides (NPs) that exerts endocrine effects on fluid homeostasis and blood pressure. Atrial Natriuretic Peptide holds promise for cardiovascular diseases research.

Galanin-Like Peptide (human) 是由60个氨基酸组成的神经肽，在调节摄食、体重和能量代谢方面具有重要功能。

This human neuropeptide of the RFamide peptide family with orexigenic activity may be also involved in the control of feeding behavior. The 26RFa gene is exclusively expressed in the ventromedial hypothalamic nucleus and in the lateral hypothalamic area.

Glucagon-like peptide 2 (GLP-2) is a recently identified intestinal epithelium-specific growth factor that has been shown to reduce the severity of inflammatory disorders of the intestine in rodent models. Currently Glucagon-Like Peptide 2 is used as a po

Peptide YY (PYY) (3-36), human trifluoroacetate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64716。

胃抑制肽(GIP) (22-51) 是一种具有30个氨基酸的前动脉硬化肽，对应于GIP前体蛋白proGIP的第22至51个氨基酸残基，已在人类血浆中发现。在1 µM的浓度下使用，该肽能引起在巨峰细胞分化的THP-1细胞和分离的人类主动脉内皮细胞中IκB-α的降解和NF-κB的核转移。在体内，GIP (22-51) 增加了ApoE-/-小鼠的动脉粥样硬化病变面积和斑块形成。

C-Peptide 2, rat, a 31-amino-acid peptide, serves as a constituent in proinsulin. It possesses the ability to hinder glucose-triggered insulin secretion.

Proinsulin C-Peptide (31-63), porcine, is a peptide derived from the cleavage of porcine proinsulin, specifically spanning the 31st to 63rd amino acid residues.

Protein Kinase C (19-35) Peptide 是PKC 假底物抑制剂 区域。Protein Kinase C (19-35) Peptide 阻断PKC 激酶结构域的底物结合位点，使PKC 的细胞质形式失活。

Protein kinase C α peptide (TFA) 为PKC-α的脂质依赖性丝氨酸/苏氨酸蛋白激酶多肽片段，关键调节细胞生存、增殖、分化、迁移及粘附等过程。

Peptide YY (PYY) is a 36-amino acid peptide and anorectic gut hormone agonist for the neuropeptide Y receptors Y1, Y2, Y5, and Y6 with EC50 values of 0.7, 0.58, 1, and 0.8 nM, respectively, for supression of forskolin-induced cAMP accumulation. PYY is cleaved in vivo to PYY (3-36) . Release of PYY occurs postprandially in proportion to calorie intake from intestinal enteroendocrine L cells, indicating it may be a satiety signal. In humans, PYY inhibits food intake and gastrointestinal transit in both lean and obese subjects.

C-Peptide 1 (rat) 为肽类化合物，作为β-catenin GSK-3β激活剂，具有调节Wnt β-catenin信号通路的功能，常用于癌症研究领域。

C-Peptide 2, rat acetate 是一种可抑制葡萄糖诱导的胰岛素分泌胰岛素原组分，由31个氨基酸残基构成的多肽和醋酸盐组成。

Amyloid precursor c-terminal peptide has the amino acid sequence Gly-Tyr-Glu-Asn-Pro-Thr-Tyr-Lys-Phe-Phe-Glu-Gln-Met-Gln-Asn. APP is best known as the precursor molecule whose proteolysis generates beta-amyloid (Aβ), a 37 to 49 amino acid peptide whose am