phenytoin sodium

Phenytoin sodium (Diphantoine) 是一种有效的电压门控钠离子通道阻滞剂，可减少小鼠乳腺肿瘤的生长和转移，具有抗癫痫活性。

Phenytoin (5,5-Diphenylhydantoin) 是一种有效的电压门控钠离子通道阻滞剂，可减少小鼠乳腺肿瘤的生长和转移，具有抗癫痫活性。

Fosphenytoin disodium (ACC-9653) 是 phenytoin 的前体药物，具有抗惊厥等活性。它是电压门控钠通道阻滞剂。

Phenytoin-d10 is intended for use as an internal standard for the quantification of phenytoin by GC- or LC-MS. Phenytoin is an anticonvulsant agent and active metabolite of fosphenytoin. Phenytoin is formed from fosphenytoin by tissue phosphatases. It inhibits neuronal voltage-gated sodium channels in a voltage-dependent manner. Phenytoin reduces the neuronal firing frequency and decreases the amplitude of excitatory post-synaptic potentials (EPSPs) in electrically stimulated rat corticostriatal slices. It protects against seizures induced by maximal electroshock (MES) in mice. Formulations containing phenytoin have been used in the treatment of tonic-clonic seizures and status epilepticus.

Fosphenytoin Sodium-d10 是 Fosphenytoin Sodium 的氘代化合物。Fosphenytoin Sodium 的 CAS 号为 92134-98-0。Fosphenytoin sodium 是 phenytoin 的前体药物，具有抗惊厥等活性。它是电压门控钠通道阻滞剂。