pde9in(s)c33

PDE9-IN-(S)-C33 ((S)-C33) 是一种有效的选择性 PDE9 抑制剂 (IC50 = 11 nM)。 PDE9-IN-(S)-C33 可用于中枢神经系统疾病和糖尿病的相关研究。

Conopressin S acetate(111317-90-9 free base) (Con-S acetate) 是从 Conus striatus 中分离出来的天然产物，与加压素 V1b 受体 (AVPR1B) 具有高亲和力，Ki 为 8.3 nM。

3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide抑制多药耐药蛋白（MRP1）。

(S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65266，CAS号为 86069-86-5。

(S)-2,3-Bis((((9H-fluoren-9-yl)methoxy)carbonyl)amino)propanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66729，CAS号为 201473-90-7。

c-Fms-IN-9 is a c-FMS inhibitor. It inhibits unphosphorylated c-FMS kinase (uFMS) and uKIT (IC50s: <0.01 μM and 0.1-1 μM).

N2-Isobutyryl-(S)-9-(2,3-dihydroxypropyl)-guanine is a Nucleoside Derivative - Acyclic nucleoside.

6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purine is a 2'-C-Methyl nucleoside; Halo-nucleoside.

CypD inhibitor C-9 is a CypD inhibitor, it attenuates mitochondrial and cellular perturbation insulted by Aß and calcium stress.

2-Amino-6-chloro-9-(2-C-methyl-β-D-ribofuranosyl)-9H-purine is a 2'-C-Methyl nucleoside; Halo-nucleoside.

2’-C-Methyl nucleoside; 2/6/8-modified nucleoside

(S)-9-(2,3-Dihydroxypropyl)-guanine is a Nucleoside Derivative - Acyclic nucleoside.

(S)-DMT-glycidol-C(Bz) is a Nucleoside Derivative - Acyclic nucleoside.

Dexamethasone exhibits anti-inflammatory activity.

2’-C-Methyl nucleoside; 2/6/8- modified nucleoside

9(S)-HETE is an enantiomer which makes up 50% of (±)9-HETE . There are no reports of 9(S)-HETE occurring as an enzymatic lipoxygenation product. Whereas 12(S)-HETE promotes adhesion of several cell lines to endothelial cell monolayes, 9(S)-HETE and other positional HETEs are without effect. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.

9(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. It can be further metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in the formation of 9,16-dihydroperoxy acid. The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to occur via formation of an unstable epoxide.

(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(naphthalen-2-yl)butanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T65848。

6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-benzyl-L-cysteine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67626，CAS号为 53298-33-2。

2-Amino-9-[(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)]-9H-purine is a 2'-C-Methyl nucleoside; 6-De-aminopurine nucleoside.

9-(2-C-methyl-β-D-ribofuranosyl)purine is a 2'-C-Methyl nucleoside; 6-De-aminopurine nucleoside.

9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME (1 g animal) enhances the antiviral IgA and IgG antibody responses induced by a nasal influenza hemagglutinin (HA) vaccine by 5.2- and 2-fold, respectively, in mice.4 1.Hamberg, M., and Hamberg, G.Peroxygenase-catalyzed fatty acid epoxidation in cereal seeds: Sequential oxidation of linoleic acid into 9(S),12(S),13(S)-trihydroxy-10(E)-octadecenoic acidPlant Physiol.110(3)807-815(1996) 2.Hong, S.S., and Oh, J.S.Inhibitors of antigen-induced degranulation of RBL-2H3 cells isolated from wheat branJ. Korean Soc. Appl. Biol. Chem.5569-74(2012) 3.Kim, C.S., Kwon, O.W., Kim, S.Y., et al.Five new oxylipins from Chaenomeles sinensisLipids49(11)1151-1159(2014) 4.Shirahata, T., Sunazuka, T., Yoshida, K., et al.Total synthesis, elucidation of absolute stereochemistry, and adjuvant activity of trihydroxy fatty acidsTetrahedron62(40)9483-9496(2006) 5.Fuchs, D., Tang, X., Johnsson, A.-K., et al.Eosinophils synthesize trihydroxyoctadecenoic acids (TriHOMEs) via a 15-lipoxygenase dependent processBiochim. Biophys. Acta Mol. Cell Biol. Lipids1865(4)158611(2020)

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pentanedioic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64724，CAS号为 121343-82-6。

9(S)-HpODE is produced by the action of arachidonate 5-LO on linoleic acid. It can be further metabolized by potato hydroperoxide dehydratase to colneleic acid.

NH2-c[X-R-L-S-X]-K-G-P-(D-2Nal) (化合物40) 作为 Ape13 的大环类似物，是一种 APJ 强效激动剂，具有较低的亲和力 (Ki=5.7 nM)。该化合物在 Gα12 路线上显示出优先的信号传递特性，并且在体内具有延长的半衰期。

(S)-9-((tert-Butyldimethylsilyl)oxy)-4,11-diethyl-4-hydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64821。

2-Amino-6-chloro-9-[(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)]-9H-purine is a 2'-C-Methyl nucleoside; Halo-nucleoside.

9-(2-C-methyl-2,3,5-tri-O-benzoyl -β-D-ribofuranosyl) purine is a 2'-C-Methyl nucleoside; 6-De-aminopurine nucleoside.

9(S)-HEPE is a monohydroxy fatty acid derived from EPA. The biological activity of 9(S)-HEPE has not been documented.

8(S),9(R)-EET是由细胞色素P450从花生四烯酸 (AA) 转化得到的二十烷酸产物。此化合物能以浓度依赖的方式扩张犬心外膜小动脉，其EC50为121 nM。

8(R),9(S)-EET，一种Epoxyeicosatrienoic acid的异构体，通过胞质环氧水解酶 (CEH) 的催化作用生成，其亲和力Km值为41μM。

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylacetic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65650，CAS号为 102410-65-1。

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-azidohexanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66683，CAS号为 159610-89-6。

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid hydrate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66731，CAS号为 204251-24-1。

(S)-9-[3-(4,4'-Dime thoxytrityloxy)-2-hydroxypropyl]-N2-isobutyrylguanine is a Nucleoside Derivative - Acyclic nucleoside.

9(S)-HODE is produced by the lipoxygenation of linoleic acid in both plants and animals.[1],[2] It has been detected in atherosclerotic plaques, as an esterified component of membrane phospholipids and in oxidized LDL particles.[3]

c-Myc inhibitor9 是一种c-Myc 抑制剂，logEC50值 ≥6。c-Myc inhibitor9 抑制异种移植裸鼠模型中肿瘤的生长。c-Myc inhibitor9 可用于癌症研究。

(S)-9-(2,3-Dihydroxypropyl)-2-amino-6-chloropurine is a Nucleoside Derivative - Acyclic nucleoside.

6-Methoxypurine-9-β-D-5’(R)-C-methylriboside 是一种嘌呤碱基，属于次黄嘌呤似物，主要在肌肉组织中发现。作为黄嘌呤在嘌呤氧化酶作用下的代谢产物，次黄嘌呤具备显著的抗炎性质，并可作为内源性 poly(ADP-ribose) polymerase (PARP) 的抑制剂。其通过抑制 PARP 活性，防止过氧亚硝酸盐引起的线粒体去极化及次级超氧化物的产生，展现出细胞保护作用。同时，次黄嘌呤也被用作缺氧的生物标志物。

9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-6-chloropurine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU0992。

c-Met-IN-9 是一种 4-苯氧基吡啶衍生物，是一种 c-Met 激酶抑制剂 (IC50: 12 nM)。c-Met-IN-9 能够诱导细胞凋亡，并显示出抗肿瘤作用。

9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid peroxidation. 9(S)-HODE cholesteryl ester can be used as a standard for analysis of chiral HODE cholesteryl esters.

(S)-GNA-C(Bz)-phosphoramidite is a Nucleoside Derivative - Acyclic nucleoside;Nucleoside Phosphoramidite.

(S)-6-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(((benzyloxy)carbonyl)amino)hexanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T65356。

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-(tert-butylthio)-L-cysteine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66172，CAS号为 73724-43-3。

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65199，CAS号为 146987-10-2。

6-Ethoxy-9-beta-D-(2-C-methyl-ribofuranosyl)purine is a Nucleoside Derivative - 6-Modified purine nucleoside, 2'-Modified nucleoside.