PC DBCO-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
PC Methyltetrazine-PEG4-NHS carbonateester is a polyethylene glycol (PEG) derived linker specifically designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].
PC Mal-NHS carbonateester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. This chemical compound plays a crucial role in facilitating the conjugation of drugs to antibodies, enabling targeted delivery and enhanced efficacy of therapeutic agents. Its unique carbonateester structure allows for efficient cleavage in the targeted environment, ensuring the controlled release of the drug payload. Its application in ADC synthesis highlights its importance in the development of innovative and targeted cancer therapies.
PC Biotin-PEG3-NHS ester is a cleavable ADC linker comprising three PEG units. This linker is specifically designed for use in the synthesis of antibody-drug conjugates (ADCs)[1].