pc mal nhs carbonate ester

PC Mal-NHS carbonate ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. This chemical compound plays a crucial role in facilitating the conjugation of drugs to antibodies, enabling targeted delivery and enhanced efficacy of therapeutic agents. Its unique carbonate ester structure allows for efficient cleavage in the targeted environment, ensuring the controlled release of the drug payload. Its application in ADC synthesis highlights its importance in the development of innovative and targeted cancer therapies.

m-PEG8-NHS ester 是一种含 8 个单元 PEG 的 ADC linker，可用于合成抗体偶联活性分子 (ADC)，可用于修饰蛋白质和多肽。

N3-PEG4-C2-NHS ester 是一种不可降解的 ADC linker，含 4 个单元 PEG 可用于合成抗体偶联活性分子 (ADC)。

N3-C4-NHS ester 是一种不可切割的 ADC 接头，用于合成抗体-药物偶联物。

Azido-PEG12-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

DBCO-PEG3-NHS ester是一种可降解的 ADC linker，可用于合成抗体偶联活性分子 。

Mal-PEG1-NHS ester 是一种可裂解的基于 PEG 的 ADC 接头，用于合成抗体-药物偶联物。它也是基于 PEG 的 PROTAC 接头，可用于 PROTAC 的合成。

Fmoc-NH-PEG8-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Fmoc-PEG12-NHS ester 是 PEG 类 PROTAC linker。可用于合成 PROTAC 分子。

Boc-NH-PEG3-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Biotin-PEG12-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Mal-amido-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Ald-Ph-NHS ester 是用于抗体-药物偶联的不可切割接头。

Boc-NH-O-C1-NHS ester 是一种属于 alkyl ether 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Tetrazine-Ph-NHCO-C3-NHS ester是一种源于PEG的PROTACs合成连接剂。

Propargyl-C1-NHS ester (4-Pentynoic Acid Succinimidyl Ester) 是一种不可切割的 ADC 接头，可用于合成抗体偶联药物。

DBCO-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

N3-Ph-NHS ester 是一种不可切割的 ADC 接头，用于合成抗体-药物偶联物。

Mal-amido-PEG8-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

(E)-TCO-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DOTA-NHS-ester 是 affibody 分子的接头，应用于小动物 PET、SPECT 和 CT。 它可用于标记放射治疗剂或成像探针以检测肿瘤。

Propargyl-PEG2-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DBCO-NHCO-PEG4-NHS ester ester is a MMP-2- and cathepsin B- (CatB) cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Mal-amido-PEG2-NHS ester is a noncleavable linker for antibody-drug conjugates (ADCs) that consists of a maleimide group and an NHS ester. The NHS ester allows for the labeling of protein primary amines (-NH2), amine-modified oligonucleotides, and other amine-containing molecules[1][2].

Bis-PEG7-NHS ester is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

NHPI-PEG2-C2-NHS ester is a noncleavable two-unit polyethylene glycol (PEG) linker commonly employed in antibody-drug conjugate (ADC) synthesis.

Azido-PEG8-NHS ester is an 8 unit PEG linker with cleavable properties, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1]. This compound also serves as a PEG- and Alkyl ether-based PROTAC linker, enabling its utilization in the synthesis of PROTACs[2].

Mal-PEG2-NHS ester is a noncleavable antibody-drug conjugate linker comprising a Maleimide moiety, a 2-unit PEG spacer, and an N-hydroxysuccinimide (NHS) ester functionality.

Propargyl-C2-NHS ester is a noncleavable linker used in antibody-drug conjugation (ADC).

m-PEG11-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Methyltetrazine-Sulfo-NHS ester (sodium) is an alkyl ether-based PROTAC linker utilized for PROTAC synthesis[1].

Bis-PEG2-NHS ester, utilized in antibody-drug conjugation (ADC), functions as a non-cleavable linker with two polyethylene glycol (PEG) units.

Biotin-PEG6-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bis-PEG5-NHS ester, a cleavable ADC linker, is used in the synthesis of antibody-drug conjugates (ADCs) [1].

m-PEG15-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG8-TFP ester is a polyethylene glycol (PEG) derivative serving as a PEG-based PROTAC linker, specifically utilized in PROTAC synthesis[1].

N-DBCO-N-bis(PEG2-C2-NHS ester) is a Polyethylene Glycol (PEG) derived linker that finds utility in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Mal-PEG4-PFP ester is a non-cleavable antibody-drug conjugate (ADC) linker that incorporates a Maleimide moiety, a 4-unit Polyethylene Glycol (PEG) backbone, and a Pentafluorophenyl (PFP) ester.

DBCO-PEG8-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azidoethyl-SS-propionic NHS ester is a cleavable linker frequently employed in the synthesis of antibody-drug conjugates (ADCs) [1].

m-PEG3-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG1-C2-NHS ester is a non-cleavable 1-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.

m-C-tri(CH2-PEG1-NHS ester) is a non-cleavable one-unit polyethylene glycol (PEG) linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].

Azido-PEG9-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG10-C2-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker that consists of a maleimide group and an N-hydroxysuccinimide (NHS) ester. The NHS ester enables efficient labeling of primary amines (-NH2) in proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

Biotin-PEG8-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

PC Alkyne-PEG4-NHS ester is a cleavable 4-unit PEG linker employed for the synthesis of antibody-drug conjugates (ADCs)[1].

Propargyl-PEG3-NHS ester, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs)[1].