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Search Results for " ovaries "

Targets Recommended: Others

7

抑制剂 & 化合物

3

天然产物

1

化合物库

4

重组蛋白

2

同位素标记化合物

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Cat. No.	Product Name
L2196	抗卵巢癌化合物库		1867 compounds
	1867 种与卵巢癌相关的化合物，可以用于抗卵巢癌药物研发和药理研究

化合物库

抗卵巢癌化合物库

Cat.No: L2196

Compounds: 1867

Cat. No.	Product Name	Target	Signaling Pathways
T4384	Halofenozide	Others	Others
	Halofenozide 是一种新的昆虫生长调节剂 (IGR)，具有苯甲酰肼结构，也是一种蜕皮激素 (ecdysteroid) 激动剂。可模拟天然昆虫蜕皮激素 20-羟基蜕皮激素的作用，
T7556	Fadrozole hydrochloride CGS 16949A,盐酸法倔唑	Aromatase	Endocrinology/Hormones
	Fadrozole hydrochloride (CGS 16949A) 是一种选择性的、有效，和非甾体类的芳香化酶抑制剂(IC50:6.4 nM)。
T5700	PDD00017273	Others	Others
	PDD00017273 是一种有效的放射增敏作用(二磷酸腺苷核糖)的水解酶 (PARG) 抑制剂，具有抗肿瘤或活性。PDD00017273 具有放射增敏作用，可用于研究上皮性卵巢。
T5317L	Cridanimod sodium XBIO-101,XBIO 101,Cycloferon,Sodium Cridanimod,Cridanimod Na,XBIO101	Others	Others
	Cridanimod can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Cridanimod is able to induce the expression of PR in endometrial cancer. In combination with a progestin, cancer cells could be eradicated thro
T76566	Fsh receptor-binding inhibitor fragment(bi-10)
	FSHreceptor-binding inhibitor fragment(bi-10) 是一种有效的 FSH 拮抗剂。FSHreceptor-binding inhibitor fragment(bi-10) 阻断 FSH 与 FSHR 的结合，并在受体水平上改变 FSH 的作用。FSHreceptor-binding inhibitor fragment(bi-10) 导致小鼠排卵抑制和卵泡闭锁。FSHreceptor-binding inhibitor fragment(bi-10) 通过下调卵巢中 FSHR 和 ERβ的过度表达来抑制卵巢癌发生。
T83666	Kisspeptin-10 (zebrafish) TFA Tyr-Asn-Leu-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2,Kp-10
	Kisspeptin-10是一种在斑马鱼的大脑、卵巢和睾丸中表达的神经肽，参与性腺发育和类固醇表达。在10 ng/ml的浓度下使用时，能提高孤立的斑马鱼卵巢滤泡中编码黄体生成素(luteinizing hormone, Lh)受体，以及孕酮受体a (Progestin receptor a, Pra)和Prb的mRNA水平。在0.1和1 µg/g的剂量下给予时，Kisspeptin-10能在雌性金鱼中增加黄体生成素的血清水平，但在雄性金鱼中则不会。
T36701	Phosphoramide mustard (cyclohexanamine)	Others	Others
	Phosphoramide mustard cyclohexanamine is the major metabolite for Cyclophosphamide , with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA adduct formation in ovarian granulosa cells, induces DNA damage and elicits the ovarian DNA repair response[1][2]. Phosphoramide mustard cyclohexanamine causes cytotoxicity through forming cross-linked DNA adducts which inhibit DNA strand separation during replication[1].Phosphoramide mustard cyclohexanamine destroys rapidly dividing ce...

化合物

Cat.No: T4384

Target: Others

Fadrozole hydrochloride

Cat.No: T7556

Synonym: CGS 16949A,盐酸法倔唑

Target: Aromatase

Cat.No: T5700

Target: Others

Cridanimod sodium

Cat.No: T5317L

Synonym: XBIO-101,XBIO 101,Cycloferon,Sodium Cridanimod,Cridanimod Na,XBIO101

Target: Others

Fsh receptor-binding inhibitor fragment(bi-10)

Cat.No: T76566

Kisspeptin-10 (zebrafish) TFA

Cat.No: T83666

Synonym: Tyr-Asn-Leu-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2,Kp-10

Phosphoramide mustard (cyclohexanamine)

Cat.No: T36701

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T20597	Alginic acid Protanal LF,褐藻酸,Snow acid algin G,Kelacid,Sazzio,Norgine	Apoptosis; Autophagy; Histamine Receptor	Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Alginic acid (Snow acid algin G) 是一种从褐海藻中提取的天然多糖，具有抗过敏和抗炎活性。 Alginic acid 抑制组胺释放，可用于食品工业。
T3405	[6]-Gingerol 6-Gingerol,gingerol,(S)-(+)-[6]Gingerol,6-姜酚	Apoptosis; AMPK	Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	[6]-Gingerol ((S)-(+)-[6]Gingerol) 是一种从生姜中分离的活性物质，具有抗癌，抗炎和抗氧化活性。
T1009	Estrone Oestrone,雌酮,Fluoroethyl,Aquacrine	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Estrone (Aquacrine) 是内源性雌激素的主要代表，由多种组织产生，尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。

天然产物

Cat.No: T20597

Synonym: Protanal LF,褐藻酸,Snow acid algin G,Kelacid,Sazzio,Norgine

Target: Apoptosis, Autophagy, Histamine Receptor

Cat.No: T3405

Synonym: 6-Gingerol,gingerol,(S)-(+)-[6]Gingerol,6-姜酚

Target: Apoptosis, AMPK

Cat.No: T1009

Synonym: Oestrone,雌酮,Fluoroethyl,Aquacrine

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00283	Lutropin subunit beta Protein, Bovine, Recombinant (His) LHB,Lutropin subunit beta,Lutropin beta chain,Luteinizing ho...	Bovine	E. coli
	Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. Lutropin subunit beta Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.0 kDa and the accession number is P04651.
TMPJ-00049	CGB Protein, Human, Recombinant (His) Chorionic gonadotrophin chain β,CG-β,Chorionic gonadotrophin...	Human	HEK293 Cells
	Choriogonadotropin subunit beta is also known as CG-beta, Chorionic gonadotrophin chain beta. It is a protein that in humans is encoded by the CGB gene. It belongs to the glycoprotein hormones subunit beta family. Choriogonadotropin subunit beta can stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
TMPK-00303	ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi) angiopoietin 2,angiopoietin-2a,angiopoitin 2,ANG-2,Tie2-liga...	Human	HEK293 Cells
	Angiopoietin-2 (Ang-2; also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Mature Ang-2 is 478 amino acids in length.Ang2 is widely expressed during development, but it is restricted postnatally to highly angiogenic tissues such as the placenta, ovaries, and uterus. It is particularly abundant in vascular endothelial cells (EC) where it is stored in intracellular Weibel Palade bodies..
TMPY-02800	CGB7 Protein, Human, Recombinant (His) chorionic gonadotropin beta subunit 7,chorionic gonadotropin...	Human	Baculovirus Insect Cells
	CGB7 (chorionic gonadotropin, beta polypeptide 7) belongs to the glycoprotein hormones subunit beta family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CGB7 gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are...

重组蛋白

Lutropin subunit beta Protein, Bovine, Recombinant (His)

Cat.No: TMPH-00283

Species: Bovine

Expression System: E. coli

CGB Protein, Human, Recombinant (His)

Cat.No: TMPJ-00049

Species: Human

Expression System: HEK293 Cells

ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00303

Species: Human

Expression System: HEK293 Cells

CGB7 Protein, Human, Recombinant (His)

Cat.No: TMPY-02800

Species: Human

Expression System: Baculovirus Insect Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0313	Estrone-d2
	Estrone-d2 是 Estrone 的氘代化合物。Estrone 的 CAS 号为 53-16-7。Aquacrine是内源性雌激素的主要代表，由多种组织产生，尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。
TMIJ-0255	Estrone-d4 Estriol EP Impurity B-d4
	Estrone-d4 是 Estrone 的氘代化合物。Estrone 的 CAS 号为 53-16-7。Aquacrine是内源性雌激素的主要代表，由多种组织产生，尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。

同位素标记化合物

Cat.No: TMIJ-0313

Cat.No: TMIJ-0255

Synonym: Estriol EP Impurity B-d4

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