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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1111 |
Pralidoxime Chloride
2-PAM chloride,吡啶醛肟甲氯,2-Pyridinealdoxime methochloride,2-PAM (chloride) |
AChE | Neuroscience |
Pralidoxime Chloride (2-PAM chloride) 是一种肟类化合物,对中毒乙酰胆碱酯酶具有恢复作用,可用于有机磷中毒的研究。 | |||
T20539 |
Pirimiphos-methyl
R 33986,甲基嘧啶磷,AI3-27699,Caswell No. 334B,PP511,Actelic |
AChE; Parasite | Microbiology/Virology; Neuroscience |
Pirimiphos-methyl (AI3-27699) 是一种速效有机磷杀虫剂和杀螨剂,对目标生物的乙酰胆碱酯酶有抑制作用。甲基嘧啶磷常用于农粮贮藏过程中甲虫、鼻甲虫、飞蛾和蝽蛄的防治。 | |||
T1250 |
Thio-TEPA
Tiofosyl,Triethylenethiophosphoramide,三亚乙基硫代磷酰胺,Tiofosfamid |
DNA Alkylator/Crosslinker; DNA Alkylation; Antibacterial; Antibiotic | DNA Damage/DNA Repair; Microbiology/Virology |
Thio-TEPA (Tiofosyl) 是一种具有抗肿瘤作用的 DNA 烷化剂。 | |||
T5844 |
Tolclofos-methyl
|
Antibacterial | Microbiology/Virology |
Tolclofos-methyl 是一种有机磷杀菌剂,广泛用于防治土传病害。 | |||
T19084 |
1-Naphthyl acetate
|
AChE | Neuroscience |
1-Naphthyl acetate 是一种有吸引力的生色底物,用于检测红细胞乙酰胆碱酯酶的活性。它具有检测有机磷农药中毒的潜力。 | |||
T40226 |
FP-Biotin
|
Others | Others |
FP-biotin is a potent organophosphorus toxicant, ideal for identifying novel biomarkers of organophosphorus toxicant exposure. It measures FAAH, ABHD6, and MAG-lipase activity, specifically in plasma studies, due to the efficient purification of biotinylated peptides through binding to immobilized avidin beads. | |||
T32074 |
Hgg 12
Hgg-12,Hgg12 |
Others | Others |
Hgg 12 is used to treat organophosphorus poisoning. | |||
T20729 |
Vamidothion
RP9895,Kilval,Trucidor,RP-9895,RP 10465,RP 9895 |
Others | Others |
Vamidothion is a polar organophosphorus insecticide and acaricide | |||
T25539 |
Iprobenfos
Ricid P,Kitazin P,Kitazin L,异稻瘟净,Ricid II |
Others | Others |
Iprobenfos (IBP) is used as an organophosphorus pesticide. | |||
T25964 |
Pirimiphos-ethyl
Primicid,Fernex,PP 211,PP-211,PP211 |
Others | Others |
Pirimiphos-ethyl is used as an organophosphorus pesticide. | |||
T38288 |
Profenofos
|
Others | Others |
Profenofos is an acetylcholinesterase-inhibiting organophosphorus pesticide on field crops, vegetables, and fruit crops [1]. [1]. Madhulika Kushwaha, et al. Kushwaha, M., et al.. Profenofos, an Acetylcholinesterase-Inhibiting Organophosphorus Pesticide: A Short Review of Its Usage, Toxicity, and Biodegradation. J Environ Qual.2016 Sep;45(5):1478-1489. | |||
T20831 |
Etrimfos
Ekamet,San197,San 197,Satisfar,San-197 |
Others | Others |
Etrimfos is an organophosphorus insecticide with high efficiency and low toxicity. | |||
T24664 |
Propaphos
Kayaphos,丙虫磷,Kayphosnac |
Others | Others |
Propaphos (Kayaphos) 是一种有机磷类杀虫剂。 | |||
T26051 |
RE 11775
RE-11775,RE11775 |
Others | Others |
RE 11775 is used as a carbamate insecticide with promising activity against organophosphorus-resistant mosquitoes. | |||
T15462 |
Haloxon
|
Others | Others |
Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants. | |||
T20674 |
Kitazine
Ritacin-P,Ricide,EBP,Ritacin P |
Others | Others |
Kitazine is an organophosphorus chemical fungicide. It is mainly used to control rice blast and has a certain effect on rice Sclerotinia sclerotiorum, sheath blight, corn leaf spot, and spot disease. | |||
T62857 |
K203
|
Others | Others |
K203 是一种有效的 tabun 抑制的 AChE 再激活剂,是一种重要的有机磷中毒解毒剂。 | |||
T69556 |
Cyanophos
|
Others | Others |
Cyanophos is a cholinesterase inhibitor used as an insecticide and avicide; for example, against rice stem borers and house flies. It is part of the chemical class of organophosphorus compounds, and is a yellow to reddish-yellow transparent liquid. | |||
T36058 |
Dibutyl-3-Hydroxybutyl Phosphate
|
Others | Others |
Dibutyl 3-hydroxybutyl phosphate is a compound produced from the metabolism of the organophosphorus solvent, tributyl phosphate (TBP). Incubation of goldfish liver microsomes in the presence of NADPH has been shown to convert TBP into dibutyl-3-hydroxybutyl phosphate and dibutyl phosphate. Dibutyl-3-hydroxybutyl phosphate has also been produced during radiolysis of TBP. | |||
T78674 |
Isopropyl dodec-11-enylfluorophosphonate
IDEFP |
FAAH | Metabolism; Neuroscience |
Isopropyl dodec-11-enylfluorophosphonate (IDEFP) 为有机磷酯类化合物,能抑制中枢大麻素受体 (cannabinoid receptor) (CB1) 并具有相似的效力抑制FAAH(IC50s = 2 nM)。 | |||
T37629 |
IDFP
|
Others | Others |
The endocannabinoids, 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA), are biologically active lipids that regulate diverse neurological and metabolic functions by activating the cannabinoid receptors, central cannabinoid (CB1) and peripheral cannabinoid (CB2). Monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH) hydrolyze 2-AG and AEA, respectively, thus terminating their biological function. IDFP is an organophosphorus compound that dually inhibits MAGL and F... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7192 |
Diethyl phosphate
Diethyl phosphoric acid,磷酸二乙酯 |
Others; Endogenous Metabolite | Metabolism; Others |
Diethyl phosphate (Diethyl phosphoric acid) 是一种常用杀虫剂Chlorpyrifos 的代谢或天然降解产物。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02903 |
PON1 Protein, Mouse, Recombinant
Pon1,Aromatic esterase 1,Serum aryldialkylphosphatase 1,Seru... |
Mouse | E. coli |
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification. PON1 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 39.4 kDa and the accession number is P52430. | |||
TMPH-02102 |
PON1 Protein, Human, Recombinant (GST)
Serum paraoxonase/arylesterase 1,K-45,Aromatic esterase 1,PO... |
Human | E. coli |
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. |