3
1
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3478 |
Ro 67-7476
|
GluR | Neuroscience |
Ro 67-7476 是mGluR1的正变位调节剂,能增强表达 rat mGluR1a 的 HEK293 细胞中谷氨酸诱导的钙释放,EC50为 60.1 nM。它是 P-ERK1/2 激动剂,可以在外源添加谷氨酸的情况下激活 ERK1/2 磷酸化 (EC50=163.3 nM)。 | |||
T31790 |
FFN200 dihydrochloride
FFN200 HCl,FFN200,FFN 200,FFN-200 |
Others | Others |
FFN200 is a vesicular monoamine transporter 2 (VMAT2) substrate that selectively traces monoamine exocytosis in both neuronal cell culture and brain tissue. | |||
TP2078 |
AC 253
|
||
Amylin (AMY3) receptor antagonist. Inhibits andrenomedulin-stimulated cAMP production in vitro. Protects against oligomeric Aβ-induced increase in intracellular Ca2+, activation of PKA, MAPK, Akt and cFOS and cell death in neuronal cell culture. Blocks el |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01172 |
CDH12 Protein, Human, Recombinant (His)
CDHB,cadherin 12, type 2 (N-cadherin 2) |
Human | HEK293 Cells |
Classic Cadherins represent a family of calcium-dependent homophilic cell-cell adhesion molecules. They confer strong adhesiveness to animal cells when they are anchored to the actin cytoskeleton via their cytoplasmic binding partners, catenins. The cadherin/catenin adhesion system plays key roles in the morphogenesis and function of the vertebrate and invertebrate nervous systems. Furthermore, this system is involved in synaptic plasticity. Recent studies on the role of individual cadherin subt... |