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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T61270 |
MDH1-IN-1
|
Others | Others |
MDH1-IN-1 (5i) 是一种有效的 MDH1 抑制剂,对 MDH1 的 IC50 为 6.79 μM,对 MDH2 的 IC50 为 >40 μM。MDH1-IN-1 具有潜在的抗癌活性,可用于研究与免疫系统相关的疾病。 | |||
T62335 |
MDH1-IN-2
|
Others | Others |
MDH1-IN-2 (7c) 是一种有效的 MDH1 抑制剂,对 MDH1 的 IC50 为 2.27 μM,对 MDH2 的 IC50 为 27.47 μM。MDH1-IN-2 具有潜在的抗癌活性,可用于研究与免疫系统相关的疾病。 | |||
T8765 |
iGOT1-01
|
Others | Others |
iGOT1-01 是一种天冬氨酸转氨酶 1 (谷氨酸草酰乙酸转氨酶 1;GOT1) 抑制剂,在 GOT1/GLOX/HRP 测定中IC50为 11.3 μM,在 MDH 偶联 GOT1 酶法测定中IC50为 85 μM。它显示出抗癌活性。 | |||
T64662 |
MDH1/2 inhibitor compound 16c
|
Others | Others |
MDH1/2 inhibitor compound 16c 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64662。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00161 |
MDH Protein, Bacillus methanolicus, Recombinant (His)
Type 3 alcohol dehydrogenase,mdh,NAD-dependent meth... |
Bacillus methanolicus | P. pastoris (Yeast) |
Catalyzes the oxidation of methanol to yield formaldehyde. It possesses a NADH-dependent formaldehyde reductase activity and cannot use NADP. MDH Protein, Bacillus methanolicus, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 42.4 kDa and the accession number is P31005. | |||
TMPH-00162 |
MDH Protein, Bacillus methanolicus, Recombinant (His & Myc & SUMO)
NAD-dependent methanol dehydrogenase,Type 3 alcohol dehydrog... |
Bacillus methanolicus | E. coli |
Catalyzes the oxidation of methanol to yield formaldehyde. It possesses a NADH-dependent formaldehyde reductase activity and cannot use NADP. MDH Protein, Bacillus methanolicus, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 59.9 kDa and the accession number is P31005. | |||
TMPH-00312 |
Malate dehydrogenase Protein, Brucella abortus, Recombinant (His & Myc & SUMO)
mdh,Malate dehydrogenase |
Brucella abortus | E. coli |
Catalyzes the reversible oxidation of malate to oxaloacetate. Malate dehydrogenase Protein, Brucella abortus, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 53.7 kDa and the accession number is B2S881. | |||
TMPJ-00956 |
MDH2 Protein, Human, Recombinant (His)
MDH2,Malate dehydrogenase,mitochondrial |
Human | HEK293 Cells |
Malate dehydrogenase, mitochondrial is a 338 amino acids protein that belongs to the LDH/MDH superfamily. MDH type 1 family. MDH2 catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and takes part in the malate-aspartate shuttle that functions in the metabolic coordination between cytosol and mitochondria. MDH2 is highly expressed in the adrenal system, small intestine, heart and panc... | |||
TMPJ-00955 |
MDH1 Protein, Human, Recombinant (His)
Cytosolic Malate Dehydrogenase,MDH1,MDHA,D... |
Human | E. coli |
Malate Dehydrogenase, Cytoplasmic (MDH1) is an enzyme which belongs to the MDH Type 2 sub-family of LDH/MDH superfamily. MDH1 is involved in the Citric Acid Cycle that catalyzes the conversion of Malate into Oxaloacetate (using NAD+) and vice versa. MDH1 should not be confused with Malic Enzyme, which catalyzes the conversion of Malate to Pyruvate, producing NADPH. MDH1 also participates in Gluconeogenesis, the synthesis of Glucose from smaller molecules. Pyruvate in the mitochondria is acted up... | |||
TMPY-02599 |
MDH1 Protein, Rat, Recombinant (His)
malate dehydrogenase 1, NAD (soluble) |
Rat | E. coli |
Malate dehydrogenases 1(MDH1 / MDHA) is a soluble form of malate dehydrogenases. Malate dehydrogenases (MDH) is a group of multimeric enzymes consisting of identical subunits usually organized as either dimer or tetramers with subunit molecular weights of 30-35 kDa. MDH has been isolated from different sources including archaea, eubacteria, fungi, plants, and mammals. MDH catalyzes the NAD/NADH-dependent interconversion of the substrates malate and oxaloacetate. This reaction plays a key part in... |