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Search Results for " intestine "

Targets Recommended: AChR

57

抑制剂 & 化合物

19

天然产物

101

重组蛋白

2

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T0786	Clidinium bromide 克利溴铵,Ro 2-3773	AChR	Neuroscience
	Clidinium bromide (Ro 2-3773) 是季胺抗毒蕈碱剂，可通过减少胃酸和减慢肠道速度，缓解痉挛和腹部疼痛的症状。
TP1086	Men 10376 TFA(135306-85-3,free) Men 10376 TFA,Neurokinin-2 receptor antagonist TFA	Neurokinin receptor	GPCR/G Protein; Neuroscience
	Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) 是一种有效的选择性速激肽 nk-2 受体拮抗剂，对大鼠小肠 nk-2 受体的 K I 值为 4.4 M。
TP2017L	GIP (1-39) acetate GIP (1-39) acetate(725474-97-5 Free base)	Others	Others
	GIP (1-39) acetate 是一种从猪肠道中纯化的胃抑制肽 (GIP)，可刺激胰岛素分泌。
T3433	TUG-891 TUG 891,TUG891	GPR	Endocrinology/Hormones; GPCR/G Protein
	TUG-891 是一种选择性的长链游离脂肪酸受体 4 (FFA4/GPR120) 的激动剂。
T38648L	Cecropin P1, porcine acetate	Endogenous Metabolite	Metabolism
	Cecropin P1, porcine acetate 是一种在 Hyalophora cecropia 和猪肠道中发现的抗菌肽。
TP1835L	Enterostatin, human, mouse, rat acetate	Endogenous Metabolite	Metabolism
	Enterostatin, human, mouse, rat acetate 是一种五肽，主要由分泌的胰腺前脂肪酶在肠道中形成。
T21867	BI-6015 2-甲基-1-(2-甲基-5-硝基苯基磺酰基)-1H-苯并[D]咪唑	Others	Others
	BI 6015 是肝细胞核因子 4α (HNF4α) 拮抗剂，可抑制已知 HNF4α 靶基因的表达。它利用 HNF4α 拮抗作用，降低胰岛素启动子活性，可用于研究癌症和糖尿病。
T1291	Cisapride 西沙必利,西沙比利,Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase	Potassium Channel; 5-HT Receptor; HER	Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Membrane transporter/Ion channel; Neuroscience; Tyrosine Kinase/Adaptors
	Cisapride (R 51619) 是一种5-HT4受体激动剂，还是 hERG 抑制剂。它可作用于肠道中的血清素受体，促进肠道蠕动，增加胃排空并减少食管反流。
TP2419	V-9-M Cholecystokinin nonapeptide V 9 M,Prepro CCK Fragment V-9-M,Val-pro-val-glu-ala-val-asp-pro-met,Cholecystokinin Precursor (24-32),V9M,V-9-M	Beta Amyloid	Neuroscience
	V-9-M Cholecystokinin nonapeptide (Prepro CCK Fragment V-9-M) 是胆囊收缩素(CCK)的前体化合物。胆囊收缩素(CCK)是一种刺激胆囊收缩和胰腺外分泌的脑肠肽，可从狗和猫的小肠中提取的，可以引起胆囊收缩。
T3625	Bempedoic acid ETC1002,ESP-55016,ETC 1002,ETC-1002	ATP Citrate Lyase; AMPK	Chromatin/Epigenetic; Metabolism; PI3K/Akt/mTOR signaling
	Bempedoic acid (ETC1002) 是一种 ATP-柠檬酸裂解酶抑制剂，可激活AMPK。它是脂质和碳水化合物代谢的调节剂。
T36503	Sodium Hydrogen Sulfide (hydrate)	Others	Others
	Sodium Hydrogen Sulfide (hydrate) 与一氧化氮一样，是一种重要的气体介质，对哺乳动物的免疫、神经、心血管和肺系统有重要影响。Sodium Hydrogen Sulfide (hydrate)是一种H2S 供体，常用于细胞和整个动物实验系统。例如，它被用来证明H2S 促进中性粒细胞迁移，减少气道炎症，保护神经轴突、心脏和肠道免受化学或缺血再灌注损伤。
T5943	4,4'-DIMETHOXYBENZIL p-Anisil,4,4'-二甲氧基苯酚酯	Others	Others
	4,4'-Dimethoxybenzil (trans-4-Sphingenine) 是人肠胃羧基酯酶抑制剂(Ki:70 nM)。
T67956L	Litoxetine HCl litoxetine HCL(86811-09-8 Free base)	5-HT Receptor	GPCR/G Protein; Neuroscience
	Litoxetine HCl 是一种选择性5-羟色胺（5-HT）再摄取抑制剂（SSRI）和混合5-羟色胺拮抗剂，可用于治疗尿失禁。Litoxetine HCl 在没有抗毒蕈碱特性的浓度下（10 nM-1 microM）引起大鼠离体食道肌肉粘膜的浓度依赖性松弛，使卡巴胆碱张力降低达37%,更高浓度的Litoxetine HCl（3微摩-300微摩）与明显的松弛有关，直至取消卡巴胆碱张力。以前在离体豚鼠肠道中证明的利托西汀的抗心律失常活性，在浓度大于1 microM 时在大鼠离体食道肌肉粘膜中发挥了作用。 Litoxetine HCl 的5-HT 释放作用可以解释利托西汀对未处理的大鼠组织中的5-HT 诱导的松弛的效力，这种效力被pCPA 处理所逆转。
T16038	Men 10376 Neurokinin-2 receptor antagonist	CDK	Cell Cycle/Checkpoint
	Men 10376 is a selective antagonist of tachykinin NK-2 receptor. It has a Ki of 4.4 μM for rat small intestine NK-2 receptor.
T70048	Sch 58053	Others	Others
	Sch 58053 is an analog of Ezetimibe and a selective inhibitor of lymphatic cholesterol transport in the intestine.
T31522	Dipropyl sulfone	Others	Others
	Dipropyl sulfone may function as an enhancer of heparin absorption in the intestine.
T71161	Thiorphan disulfide	Others	Others
	Thiorphan disulfide is an impurity of Racecadotril -- an antidiarrheal and enkephalinase inhibitor that reduces the amount of water and electrolytes absorbed into the intestine.
T15462	Haloxon	Others	Others
	Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants.
T37204	CCK (26-31) (non-sulfated)
	CCK (26-31) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety.
T38648	Cecropin P1, porcine
	Cecropin P1, porcine is an antibacterial peptide originally identified in moths (Hyalophora cecropia) and later in pig intestine.
T69033	Magnesium Oxaloacetate	Others	Others
	Magnesium Oxaloacetate is an inhibitor of the amebicidal activity of activated murine macrophages, helping the parasite to survive within the mouse large intestine and increasing the survival of C. elegans exposed to H2O2.
T84957	4-Aminobenzylphosphonic Acid 4-ABPA	Others	Others
	4-Aminobenzylphosphonic acid, an inhibitor of alkaline phosphatase (Ki= 1.1 mM for the bovine intestine enzyme), is utilized in affinity chromatography for alkaline phosphatase purification and in the electrochemical modification of glassy carbon electrodes.
T39187	Gliadin p31-43 Gliadin p31-43
	Gliadin p31-43, an undigested peptide derived from gliadin, prompts an innate immune response in the intestine and disrupts endocytic trafficking. Moreover, its utilization in celiac disease research has proven beneficial.
T82308	GLP-2 (1-34) (human)
	GLP-2 (1-34) (human) 是一种肠道多肽，其在进食后数分钟内释放，并可用于研究骨重塑过程。
T80881	Valosin (porcine)
	Valosin (porcine)是一种含有25个氨基酸的生物活性肽，最近从猪肠中分离得到，主要用于消化系统研究。
T41028	α-Glucosidase α-D-Glucosidase,α-葡萄糖苷酶	Others	Others
	α-Glucosidase (α-D-Glucosidase) is a carbohydrate hydrolyzing enzyme that catalyzes the release of α-glucose from the non-reducing end of the substrate. It plays a vital role in facilitating glucose absorption by the small intestine. Inhibiting α-Glucosidase effectively manages non-insulin-dependent diabetes mellitus (NIDDM).
T26237	Sulisatin DAN 603,Laxitex,DAN603,Sulisatinum,DAN-603	Others	Others
	Sulisatin 是一种泻药。它在大肠中被肠道菌群水解为其二苯衍生物BHMI，BHMI 负责药物的通便活性。
T75786	Enterostatin(human,mouse,rat) TFA
	Enterostatin (human,mouse,rat) TFA, 作为一种五肽，主由胰前脂酶在肠道中裂解生成。它能选择性降低脂肪摄取、体重及体脂。
T37203	CCK (26-30) (sulfated)
	CCK (26-30) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-30) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 10% when used at a concentration of 0.1 mM.
T82311	Gliadin p31-43 TFA
	Gliadin p31-43 TFA 是一种未消化gliadin peptide，可诱导肠道先天性免疫反应并干扰内吞运输，用于乳糜泻研究。
T70605	NaPi2b Inhibitor 15	Others	Others
	NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. The inhibition of NaPi2b, responsible for intestinal phosphate absorption, is considered to reduce serum phosphate levels, making it a promising therapeutic approach for hyperphosphatemia
T69066	Forphenicine	Others	Others
	Forphenicine is a bacterial metabolite that has been found in S. fulvoviridis and an inhibitor of alkaline phosphatase (IC50 = 0.036 µg/ml for the chicken intestine enzyme). It inhibits the growth of HL-60 leukemia cells when used at a concentration of 10 µM. Forphenicine (50 and 500 µg/animal) increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE).
TP1487	Glucagon-Like Peptide (GLP) II, human
	Glucagon-like peptide 2 (GLP-2) is a recently identified intestinal epithelium-specific growth factor that has been shown to reduce the severity of inflammatory disorders of the intestine in rodent models. Currently Glucagon-Like Peptide 2 is used as a po
T71340	Mizagliflozin sebacate	Others	Others
	Mizagliflozin sebacate is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine with a novel mechanism of action different from that of conventional alpha-glucosidase inhibitors. Mizagliflozin blocks intestinal glucose absorption and reduce GIP secretion in rats and humans, suggesting SGLT1 glucose transport is critical for GIP release.
T60641	Vanin-1-IN-2	Others	Others
	Vanin-1-IN-2 是vanin-1的有效抑制剂(IC 50 = 162 nM)。Vanin-1 是在肾脏、肝脏和小肠中高水平表达的细胞表面相关的糖基磷脂酰肌醇 (GPI) 锚定蛋白。
T37205	CCK (26-31) (sulfated)
	CCK (26-31) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-31) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 21% when used at a concentration of 0.1 mM.
T75879	Men 10376 TFA
	Men 10376 TFA 是一种有效的选择性的 tachykinin NK-2受体拮抗剂，对大鼠小肠 NK-2 受体的Ki 值为 4.4 μM。
T75823	GLP-2(rat) TFA
	GLP-2(rat) TFA为肠道生长因子，能刺激细胞增殖、抑制凋亡，且在大肠小肠切除术(MSBR)后，可提升残留小肠粘膜的品质与功能。
T63819	Domperidone monomaleate	Others	Others
	Domperidone (R33812) monomaleate 是选择性的、口服具有活力的多巴胺-2 受体 (dopamine-2 receptor) 拮抗剂。Domperidone monomaleate 能够影响胃和小肠的化学感受器触发区和运动功能，具有止吐和促动力剂作用。
T76001	Apraglutide TFA
	Apraglutide TFA (FE 203799 TFA) 是一种合成的、含33个氨基酸的肽类药物，为长效GLP-2类似物。它能在全回肠切除后导致的新生短肠综合征小猪中增强适应性和线性肠生长。
T0366L	Cefadroxil (hydrate)	Others	Others
	Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug's uptake across the apical membrane of small intestine.
T37021	Enteropeptidase Fluorogenic Substrate	Others	Others
	Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase is a serine protease expressed in the proximal small intestine of higher animals that converts inactive trypsinogen to active trypsin by endoproteolytic cleavage. Enteropeptidase recognizes the highly specific amino acid sequence DDDDK on the fluorogenic substrate and cleaves after the lysine residue, releasing the AFC moiety. Enteropeptidase ac...
T81539	PAT1inh-B01	Others	Others
	PAT1inh-B01为选择性SLC26A6抑制剂，抑制PAT1（Cl-/HCO3-交换器）介导的阴离子交换（IC50: 350 nM），并阻断小肠液体吸收，适用于小肠分泌不足相关疾病研究。
T37022	Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt)	Others	Others
	Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase is a serine protease expressed in the proximal small intestine of higher animals that converts inactive trypsinogen to active trypsin by endoproteolytic cleavage.1,2Enteropeptidase recognizes the highly specific amino acid sequence DDDDK on the fluorogenic substrate and cleaves after the lysine residue, releasing the AFC moiety. Enteropeptidase ...
T37519	Diquat (bromide)	Others	Others
	Diquat is a bipyridylium herbicide that, as a stable radical, acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen, producing reactive oxygen species (ROS).1Diquat administration has been used to induce oxidative stressin vitroand in animal models.2,3,4It increases the production of ROS and decreases the mitochondrial membrane potential in mitochondria isolated from porcine intestine leading to mitophagy when administered at a dose of 100 mg/kg.2Form...
T64553	GLP-1(7-37) TFA salt	Others	Others
	The truncated glucagon-like peptides GLP-1(7-37) is naturally occurring peptide product of the preproglucagon gene that are synthesized primarily in the intestine and acts as incretin that are released from the intestine into the bloodstream in response to food and stimulate insulin secretion. GLP-1(7-37) produced a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in Sprague-Dawley Rats at a dosing rang of 0.5, ...
T37757	Tyvelose	Others	Others
	Tyvelose is an unusual 3,6-dideoxyhexose terminal sugar and the immunodominant component of glycoprotein antigens in the parasitic helminth T. spiralis, which is responsible for trichinosis in humans. It is produced in high amounts by the infective larva and is immunodominant during the muscle stage of infection. Mice immunized with tyvelose-BSA produce IgG1 antibodies to tyvelose but are not resistant to infection by T. spiralis. Tyvelose-specific antibodies (2.5 mg/20 g) administered to rat pu...
T37206	CCK (27-33) (non-sulfated)
	CCK (27-33) is a C-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes (IC50 = 4 uM) and inhibits electrically-stimulated contraction of isolated guinea pig ileum (IC50 = 17 uM), an effect that can be reversed by naloxone. Unlike sulfated CCK (27-33), the non-sulfated form does not reduce exploratory behavior in m...
T38291	C24 Phytosphingosine (t18:0/24:0)	Others	Others
	C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t18:0/24:0) is composed of a phytosphingosine backbone amine-linked to a C24 fatty acid chain. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro. In a stratum corneum model of healthy skin, the inco...
T38180	C16 Phytoceramide (t18:0/16:0)	Others	Others
	C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C16 Phytoceramide (t18:0/16:0) is composed of a phytosphingosine backbone amine-linked to a C16 fatty acid chain. The levels of C16 phytoceramide (t18:0/16:0) increase following heat stress in S. cerevisiae. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous ...

化合物

Clidinium bromide

Cat.No: T0786

Synonym: 克利溴铵,Ro 2-3773

Target: AChR

Men 10376 TFA(135306-85-3,free)

Cat.No: TP1086

Synonym: Men 10376 TFA,Neurokinin-2 receptor antagonist TFA

Target: Neurokinin receptor

GIP (1-39) acetate

Cat.No: TP2017L

Synonym: GIP (1-39) acetate(725474-97-5 Free base)

Target: Others

Cat.No: T3433

Synonym: TUG 891,TUG891

Target: GPR

Cecropin P1, porcine acetate

Cat.No: T38648L

Target: Endogenous Metabolite

Enterostatin, human, mouse, rat acetate

Cat.No: TP1835L

Target: Endogenous Metabolite

Cat.No: T21867

Synonym: 2-甲基-1-(2-甲基-5-硝基苯基磺酰基)-1H-苯并[D]咪唑

Target: Others

Cat.No: T1291

Synonym: 西沙必利,西沙比利,Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase

Target: Potassium Channel, 5-HT Receptor, HER

V-9-M Cholecystokinin nonapeptide

Cat.No: TP2419

Synonym: V 9 M,Prepro CCK Fragment V-9-M,Val-pro-val-glu-ala-val-asp-pro-met,Cholecystokinin Precursor (24-32),V9M,V-9-M

Target: Beta Amyloid

Cat.No: T3625

Synonym: ETC1002,ESP-55016,ETC 1002,ETC-1002

Target: ATP Citrate Lyase, AMPK

Sodium Hydrogen Sulfide (hydrate)

Cat.No: T36503

Target: Others

4,4'-DIMETHOXYBENZIL

Cat.No: T5943

Synonym: p-Anisil,4,4'-二甲氧基苯酚酯

Target: Others

Cat.No: T67956L

Synonym: litoxetine HCL(86811-09-8 Free base)

Target: 5-HT Receptor

Cat.No: T16038

Synonym: Neurokinin-2 receptor antagonist

Target: CDK

Cat.No: T70048

Target: Others

Dipropyl sulfone

Cat.No: T31522

Target: Others

Thiorphan disulfide

Cat.No: T71161

Target: Others

Cat.No: T15462

Target: Others

CCK (26-31) (non-sulfated)

Cat.No: T37204

Cecropin P1, porcine

Cat.No: T38648

Magnesium Oxaloacetate

Cat.No: T69033

Target: Others

4-Aminobenzylphosphonic Acid

Cat.No: T84957

Synonym: 4-ABPA

Target: Others

Cat.No: T39187

Synonym: Gliadin p31-43

GLP-2 (1-34) (human)

Cat.No: T82308

Valosin (porcine)

Cat.No: T80881

Cat.No: T41028

Synonym: α-D-Glucosidase,α-葡萄糖苷酶

Target: Others

Cat.No: T26237

Synonym: DAN 603,Laxitex,DAN603,Sulisatinum,DAN-603

Target: Others

Enterostatin(human,mouse,rat) TFA

Cat.No: T75786

CCK (26-30) (sulfated)

Cat.No: T37203

Gliadin p31-43 TFA

Cat.No: T82311

NaPi2b Inhibitor 15

Cat.No: T70605

Target: Others

Cat.No: T69066

Target: Others

Glucagon-Like Peptide (GLP) II, human

Cat.No: TP1487

Mizagliflozin sebacate

Cat.No: T71340

Target: Others

Cat.No: T60641

Target: Others

CCK (26-31) (sulfated)

Cat.No: T37205

Cat.No: T75879

Cat.No: T75823

Domperidone monomaleate

Cat.No: T63819

Target: Others

Apraglutide TFA

Cat.No: T76001

Cefadroxil (hydrate)

Cat.No: T0366L

Target: Others

Enteropeptidase Fluorogenic Substrate

Cat.No: T37021

Target: Others

Cat.No: T81539

Target: Others

Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt)

Cat.No: T37022

Target: Others

Diquat (bromide)

Cat.No: T37519

Target: Others

GLP-1(7-37) TFA salt

Cat.No: T64553

Target: Others

Cat.No: T37757

Target: Others

CCK (27-33) (non-sulfated)

Cat.No: T37206

C24 Phytosphingosine (t18:0/24:0)

Cat.No: T38291

Target: Others

C16 Phytoceramide (t18:0/16:0)

Cat.No: T38180

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TJS0928	Calenduloside E 去葡萄糖竹节参皂苷,Silphioside F	Others	Others
	Calenduloside E (Silphioside F) 是从辽东楤木中提取的一种五环三萜皂苷。它靶向热休克蛋白90 (Hsp90) ，具有抗凋亡作用。
TN1528	Cotoin	AChE	Neuroscience
	Cotoin 是从 Garcinia virgate 茎皮中分离出的一种天然产物。Cotoin 具有解痉活性，可降低孤立的兔肠的音调和收缩。它部分抑制乙酰胆碱、毛果芸香碱和 BaCl 对分离肠的影响。
T1016	D-α-Tocopherol acetate 乙酸维生素E,Vitamin E Acetate,Tocopherol acetate	Endogenous Metabolite	Metabolism
	D-α-Tocopherol acetate (Vitamin E Acetate) 能够水解为 d-α-生育酚 (VE) 并被小肠吸收。
T2S1840	Rebaudioside D 莱苞迪苷D,瑞鲍迪甙D	Others	Others
	Rebaudioside D 是一种苷类化合物，存在于甜菊叶中，可用作甜味剂。
T0966	Sennoside A 番泻苷A,NSC 112929,番泻苷 A	MAO; HIV Protease	Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Sennoside A (NSC-112929) 是在番泻叶的叶子和豆荚中大量发现的蒽醌苷，抑制 HIV-1 复制。
T74293	Allolithocholic acid	Others	Others
	Allolithocholic acid 是一种类固醇酸，在正常血清和粪便中可发现。该化合物促进脂肪与甾醇在肠道及肝脏的排泄、吸收与运输。
T2215	Ferulic Acid Coniferic acid,Fumalic Acid,阿魏酸	FGFR; Endogenous Metabolite	Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors
	Ferulic Acid (Coniferic acid) 是新型的成纤维细胞生长因子受体 1 (FGFR1)抑制剂, 在FGFR1和FGFR2的IC50分别为 3.78 和 12.5 μM。
TN6393	fulvotomentoside A	Others	Others
	fulvotomentoside A 可降低肠道中 IL-6 和 IL-17A 的过表达，并显着增加调节性 T 细胞特异性转录因子 Foxp3 的表达。这可能是Ful 改善肠道炎症的机制之一。
T3S0509	Gaultherin	COX	Immunology/Inflammation; Neuroscience
	Gaultherin 是一种分离自 Gaultheria yunnanensis 中的天然水杨酸酯衍生物。它是一种非甾体类抗炎药，具有止痛和抗炎作用，与 Aspirin 相比没有胃溃疡作用。
T13506	3β-Ursodeoxycholic acid Isoursodeoxycholic acid
	3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) 是一种胆汁酸。3β-Ursodeoxycholic acid 经口服给药表现出良好的耐受性和良好的肠道吸收能力。3β-Ursodeoxycholic acid 可以在肠道和肝脏经历酶异构化，并生成UDCA。
T15824	Lysergol	Antibacterial	Microbiology/Virology
	Lysergol 已被用作一种降血压、精神镇痛药以及刺激子宫和肠道的药物。 Lysergol 是从 Ipomoea muricata 的种子中分离出来的一种棒状生物碱，是药物和营养物质的生物增强剂，具有抗菌活性。
T19124	3-Oxocholic acid 3-Ketocholic acid	Endogenous Metabolite	Metabolism
	3-Oxocholic acid(3-Ketocholic acid) 是胆汁酸的代谢产物，也是产气荚膜梭菌在肠道中由胆汁降解的主要产物。33-Oxocholic acid 是一种主要存在于哺乳动物的胆汁中类固醇酸。
T0847	Chenodeoxycholic acid CDCA,鹅去氧胆酸,Chenodiol	Potassium Channel; FXR; Endogenous Metabolite; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Chenodeoxycholic acid (CDCA) 是一种胆汁酸，通常与甘氨酸或牛磺酸结合。它作为清洁剂溶解脂肪以供肠道吸收，并被小肠重新吸收。它被用作利胆剂、利胆泻药，以及预防或溶解胆结石。
T3S1967	(S)-Indoximod N-ME-Tryptophan,Abrine,相思豆碱,L-Abrine	Others; Indoleamine 2,3-Dioxygenase (IDO)	Metabolism; Others
	(S)-Indoximod (L-Abrine) 是一种吲哚胺-2,3-双加氧酶 (IDO) 抑制剂，可用于研究癌症。
T5S1988	Isorhamnetin-3-O-glucoside Isorhamnetin-3-O-beta-D-Glucoside,异鼠李素-3-O-葡萄糖苷	Others	Others
	Isorhamnetin-3-O-glucoside (Isorhamnetin-3-O-beta-D-Glucoside) 是一种天然化合物，广泛存在于蔬菜和水稻中，经消化后可在肠道菌群中代谢。
T1040	Vitamin B12 Cyanocobalamin,Cobalamin,维生素B12	Endogenous Metabolite	Metabolism
	Vitamin B12 (Cobalamin) 是一种维生素，在维持血流形成和脑、神经系统正常功能等方面发挥关键作用。
TJS0387	Desoxyrhaponticin 去氧土大黄苷,Deoxyrhapontin,脱氧土大黄苷,Deoxyrhaponticin	Apoptosis; Fatty Acid Synthase	Apoptosis; Metabolism
	Desoxyrhaponticin (Deoxyrhaponticin) 是来自西藏营养食品唐古特大黄中的一种二苯乙烯苷。它是脂肪酸合成酶抑制剂，抑制细胞内 FAS 活性，下调人乳腺癌 MCF-7细胞中 FAS 的表达。它是控制糖尿病餐后高血糖的潜在药物。
T82032	Isoglobotriaose Gala-3Galb-4Glc
	Isoglobotriaose (Gala-3Galb-4Glc)是哺乳动物组织中的一种糖鞘脂，属于球状三脂糖的类似物。其神经节苷脂衍生物isoglobotriaosylceramide特定分布于小肠非上皮细胞的残基中，而globotriaosylceramide则在两种细胞隔室中都有分布。
T37810	6',7'-Epoxybergamottin	Others	Others
	6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, and 0.22 μM in S9 human intestine cells. It has been studied in the context of drug interactions with grapefruit constituents. It is found in grapefruit juice at concentrations of 0.1-7.4 μM and inhibits the transport of talinolol , a permeability glycoprotein (P-gp/ABCB1) transpo...

天然产物

Calenduloside E

Cat.No: TJS0928

Synonym: 去葡萄糖竹节参皂苷,Silphioside F

Target: Others

Cat.No: TN1528

Target: AChE

D-α-Tocopherol acetate

Cat.No: T1016

Synonym: 乙酸维生素E,Vitamin E Acetate,Tocopherol acetate

Target: Endogenous Metabolite

Cat.No: T2S1840

Synonym: 莱苞迪苷D,瑞鲍迪甙D

Target: Others

Cat.No: T0966

Synonym: 番泻苷A,NSC 112929,番泻苷 A

Target: MAO, HIV Protease

Allolithocholic acid

Cat.No: T74293

Target: Others

Cat.No: T2215

Synonym: Coniferic acid,Fumalic Acid,阿魏酸

Target: FGFR, Endogenous Metabolite

fulvotomentoside A

Cat.No: TN6393

Target: Others

Cat.No: T3S0509

Target: COX

3β-Ursodeoxycholic acid

Cat.No: T13506

Synonym: Isoursodeoxycholic acid

Cat.No: T15824

Target: Antibacterial

3-Oxocholic acid

Cat.No: T19124

Synonym: 3-Ketocholic acid

Target: Endogenous Metabolite

Chenodeoxycholic acid

Cat.No: T0847

Synonym: CDCA,鹅去氧胆酸,Chenodiol

Target: Potassium Channel, FXR, Endogenous Metabolite, Autophagy

Cat.No: T3S1967

Synonym: N-ME-Tryptophan,Abrine,相思豆碱,L-Abrine

Target: Others, Indoleamine 2,3-Dioxygenase (IDO)

Isorhamnetin-3-O-glucoside

Cat.No: T5S1988

Synonym: Isorhamnetin-3-O-beta-D-Glucoside,异鼠李素-3-O-葡萄糖苷

Target: Others

Cat.No: T1040

Synonym: Cyanocobalamin,Cobalamin,维生素B12

Target: Endogenous Metabolite

Desoxyrhaponticin

Cat.No: TJS0387

Synonym: 去氧土大黄苷,Deoxyrhapontin,脱氧土大黄苷,Deoxyrhaponticin

Target: Apoptosis, Fatty Acid Synthase

Isoglobotriaose

Cat.No: T82032

Synonym: Gala-3Galb-4Glc

6',7'-Epoxybergamottin

Cat.No: T37810

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05352	Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (hFc) cadherin 17, LI cadherin (liver-intestine)	Cynomolgus	HEK293 Cells
	Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 111.8 kDa and the accession number is XP_005563762.1.
TMPY-02919	Cadherin 17/CDH17 Protein, Rat, Recombinant (His) cadherin 17, LI cadherin (liver-intestine)	Rat	HEK293 Cells
	Cadherin 17/CDH17 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is P55281.
TMPY-01912	Cadherin 17/CDH17 Protein, Human, Recombinant (His) HPT-1,cadherin 17, LI cadherin (liver-intestine),CD...	Human	HEK293 Cells
	Cadherin 17/CDH17 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87 kDa and the accession number is Q12864-1.
TMPY-06645	Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (His) cadherin 17, LI cadherin (liver-intestine)	Cynomolgus	HEK293 Cells
	Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.94 kDa and the accession number is XP_005563762.2.
TMPY-06324	Cadherin 17/CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated cadherin 17, LI cadherin (liver-intestine),HPT1,CDH...	Human	HEK293 Cells
	Cadherin 17/CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 88.24 kDa and the accession number is Q12864-1.
TMPJ-00590	ANXA13 Protein, Human, Recombinant Intestine-Specific Annexin,Annexin A13,ISA,Annexin-...	Human	E. coli
	Annexin A13 (ANXA13) belongs to the annexin family which plays a role in phospholipase inhibition, cytoskeletal interactions, intracellular signal transduction pathways and regulation of cellular growth. ANXA13 contains four annexin repeats and a pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA13 is highly expressed in intestinal and kidney epithelial cells. The specific function of ANXA13 has not yet been determined; however it is associated with the plasma m...
TMPH-00481	ANXA13 Protein, Canine, Recombinant (His) Annexin-13,Annexin XIII,Annexin A13,Intestine-speci...	Canine	P. pastoris (Yeast)
	ANXA13 Protein, Canine, Recombinant (His) is expressed in Yeast.
TMPJ-00583	CDH17 Protein, Human, Recombinant (His) Intestinal Peptide-Associated Transporter HPT-1,Liver-In...	Human	HEK293 Cells
	Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks the conserved cytoplasmic domain. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells. Cadherin-17 may have a role...
TMPH-02027	RETNLB Protein, Human, Recombinant (His) Colon carcinoma-related gene protein,Colon and small int...	Human	E. coli
	Probable hormone. RETNLB Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 13.4 kDa and the accession number is Q9BQ08.
TMPY-03221	Intrinsic Factor Protein, Human, Recombinant (His) IF,IFMH,gastric intrinsic factor (vitamin B synthesis),INF,T...	Human	HEK293 Cells
	Gastric intrinsic factor, also known as GIF, belongs to the of the cobalamin transport protein family. It is a glycoprotein produced by the parietal cells of the stomach. Gastric intrinsic factor plays a key role in the absorption of vitamin B12 on in the small intestine. Vitamin B12 bounds to haptocorrin after entry into the stomach. The resulting complex enters the duodenum, where pancreatic enzymes digest haptocorrin. In the less acidic environment of the small intestine, B12 can then bind to...
TMPY-03274	CXCL11 Protein, Human, Recombinant SCYB9B,I-TAC,chemokine (C-X-C motif) ligand 11,H174,SCYB11,I...	Human	E. coli
	I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC ...
TMPJ-00662	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli) Receptor activator of nuclear factor kappa-B ligand,Receptor...	Human	E. coli
	CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). When RANKL binds to RANK, it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6). This results in the activation of several downstream signaling cascades, including the NFκB, mitog...
TMPH-02667	Galactosylceramidase Protein, Mouse, Recombinant Galactocerebroside beta-galactosidase,Galactocerebrosidase,G...	Mouse	E. coli
	Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.
TMPH-03703	Zot Protein, Vibrio cholerae serotype O1, Recombinant (His) Zona occludens toxin,Zonular occludens toxin,zot	Vibrio cholerae	E. coli
	Increases the permeability of the small intestine mucosa by affecting the structure of intercellular tight junctions (zonula occludens). Zot Protein, Vibrio cholerae serotype O1, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 48.4 kDa and the accession number is P38442.
TMPY-01579	GBA3 Protein, Human, Recombinant (His) glucosidase, beta, acid 3 (gene/pseudogene),GBA3,MGC126878,K...	Human	Baculovirus Insect Cells
	Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in r...
TMPJ-00529	FABP6 Protein, Human, Recombinant (His) Ileal Lipid-Binding Protein,I-BABP,Intestinal Bile Acid-Bind...	Human	E. coli
	Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine to the ileum where it is involved in the enterohepatic circulation of bile acids. FABP6 forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level)...
TMPJ-01248	Cytoglobin/CYGB Protein, Human, Recombinant (His) Stellate Cell Activation-Associated Protein,Cytoglobin,CYGB,...	Human	E. coli
	Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be involved in intracellular oxygen storage or transfer, modulates oxygen and nitric oxide metabolism or scavenging free radicals within a cell.
TMPJ-00686	B4GALT3 Protein, Human, Recombinant (His) β-1,4-galactosyltransferase 3,Beta-1,B4GALT3	Human	HEK293 Cells
	Beta-1,4-galactosyltransferase 3 (B4GALT3) belongs to the glycosyltransferase 7 family. It is responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. It is highest expression in placenta, prostate, testis, ovary, intestine and muscle, and in fetal brain.
TMPJ-00057	REG3G Protein, Human, Recombinant (hFc) PAP-1B,REG3G,Regenerating islet-derived protein III-γ,Regene...	Human	HEK293 Cells
	Pancreatitis-associated protein IB, Regenerating islet-derived protein III-gamma, is a secreted protein which contains 1 C-type lectin domain. It is expressed almost exclusively in the pancreas and also expressed in testis, but not found in small intestine. This protein might be a stress protein involved in the control of bacterial proliferation.
TMPH-03329	Mcpt2 Protein, Rat, Recombinant (His & Myc) Mast cell protease 2,Mcpt2,Mast cell protease II,Group-speci...	Rat	E. coli
	This enzyme, isolated from small intestine, specifically inactivates the apo forms of a certain group of intracellular pyridoxal phosphate-requiring enzymes. It has chymotrypsin-like specificity towards small substrates. Mcpt2 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is P00770.
TMPJ-00665	ADAMDEC1 Protein, Human, Recombinant (His) a disintegrin and metalloproteinase domain-like protein decy...	Human	HEK293 Cells
	ADAM DEC1 protein is expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. ADAM DEC1 is induced during DC maturation and up-regulated in response to T-cell signals. It may play an important role in the control of the immune response and during pregnancy.
TMPJ-00440	BTNL4 Protein, Mouse, Recombinant (His) EG632126,BTNL4,NG11,BTN3A3	Mouse	HEK293 Cells
	Butyrophilin-like 4, also known as BTLN4, BTN3A3 (human) and BTN3A2 (rat) is an approximately 65 kDa member of the butyrophilin family that may play a role in immune regulation. BTNL4 shows striking sequence similarity to Skint1, is also largely restricted to an epithelial tissue (the small intestine) replete with T cells, plays a role in T-cell responses in the adaptive immune response.
TMPJ-00956	MDH2 Protein, Human, Recombinant (His) MDH2,Malate dehydrogenase,mitochondrial	Human	HEK293 Cells
	Malate dehydrogenase, mitochondrial is a 338 amino acids protein that belongs to the LDH/MDH superfamily. MDH type 1 family. MDH2 catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and takes part in the malate-aspartate shuttle that functions in the metabolic coordination between cytosol and mitochondria. MDH2 is highly expressed in the adrenal system, small intestine, heart and panc...
TMPK-00952	CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc) BILL-cadherin,Cadherin-17,LI-cadherin,CDH16,cadherin-16,Cdh1...	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc) is exp...
TMPK-00947	CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated CDH16,Cdh17,P130,cadherin-16,HPT-1,LI-cadherin,Cadherin-17,B...	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated...
TMPK-00950	CDH17 Domain 6-7 Protein, Human, Recombinant (hFc) HPT-1,P130,MGC138218,LI-cadherin,FLJ26931,cadherin-16,Cdh17,...	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 6-7 Protein, Human, Recombinant (hFc) is expre...
TMPK-01223	CDH17 Protein, Mouse, Recombinant (His) CDH16,LI-cadherin,Cdh17,MGC138218,HPT-1,MGC142024,FLJ26931,B...	Mouse	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Mouse, Recombinant (His) is expressed in HEK...
TMPK-00473	CDH17 Protein, Rhesus macaque, Recombinant (His) CDH16,Cdh17,MGC142024,Cadherin-17,cadherin-16,P130,MGC138218...	Rhesus	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Rhesus macaque, Recombinant (His) is express...
TMPJ-00974	XCL1 Protein, Human, Recombinant (hFc & His) Cytokine SCM-1,Lymphotaxin,LTN,XC chemokine ligand 1,Small-i...	Human	HEK293 Cells
	Lymphotactin is a secreted protein which belongs to the intercrine gamma family. It is also a member of the XC chemokine family. XCL1 is found in spleen with highest level, lower in peripheral leukocytes and very low levels in lung, colon and small intestine. XCL1 plays a role in inflammatory and immunological responses, inducing leukocyte migration and activation. XCL1 induces chemotactic function by binding to a chemokine receptor called XCR1. XCL1 is closely related to another chemokine calle...
TMPK-00555	CDH17 Protein, Cynomolgus, Recombinant (His) Cdh17,HPT-1,FLJ26931,LI-cadherin,BILL-cadherin,P130,Cadherin...	Cynomolgus	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Cynomolgus, Recombinant (His) is expressed i...
TMPK-00948	CDH17 Protein, Human, Recombinant (hFc) Cdh17,cadherin-16,FLJ26931,Cadherin-17,HPT-1,P130,CDH16,LI-c...	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (hFc) is expressed in HEK...
TMPK-01224	CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated P130,BILL-cadherin,LI-cadherin,MGC138218,FLJ26931,CDH16,Cadh...	Mouse	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant ...
TMPK-00949	CDH17 Domain 7 Protein, Human, Recombinant (hFc) CDH16,P130,MGC142024,Cdh17,FLJ26931,Cadherin-17,MGC138218,ca...	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is express...
TMPY-04058	RGS5 Protein, Human, Recombinant (His) MST106,MSTP032,MST092,regulator of G-protein signaling 5,MST...	Human	E. coli
	RGS5 is a member of the RGS superfamily and acts as a negative regulator of heterotrimeric G protein-mediated signalling through G protein-coupled receptors (GPCRs). The regulator of G-protein signaling (RGS) proteins have recently been identified as signal transduction molecules which have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. The messenger RNA of hRGS5 was abundantly expressed in heart, lung, skeletal muscle, and small intestine, and at l...
TMPY-03867	CBR3 Protein, Human, Recombinant (His) SDR21C2,carbonyl reductase 3,hCBR3,HEL-S-25	Human	E. coli
	CBR3, also known as hCBR3, belongs to the short-chain dehydrogenases/reductases (SDR) family. CBR3 is expressed in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis. It is a monomeric NADPH-dependent oxidoreductase and is closely linked to another carbonyl reductase gene – CBR1. CBR3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It has lo...
TMPJ-00114	EFNA3 Protein, Mouse, Recombinant (hFc) EFL2,LERK-3,EFNA3,Ephrin-A3,EHK1-L,EPLG3,EFL-2,EHK1 Ligand,L...	Mouse	HEK293 Cells
	Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. Ephrin-A3 has a GPI anchor following the extracellular sequence and a signal sequence of 22 amino acids. Ephrin-A3 can bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8 and EphB1. Futhe...
TMPK-01087	Apolipoprotein A-V/APOA5 Protein, Mouse, Recombinant (His) ApoA-V,Apolipoprotein A-V,Rap3,Apoa5,Apo-AV,Apolipoprotein A...	Mouse	E. coli
	APOA5 is probably the gene with the strongest effect on triglyceride (TG) metabolism. APOA5 is almost exclusively expressed in the liver, and its product apoAV has a very low circulating concentration. New physiological roles of apoAV have been recently elucidated, such as control of chylomicron production in the intestine and TG accumulation in adipose tissue.The key role of APOA5 in TG metabolism has been largely shown through genetic studies in association with either severe or moderate hyper...
TMPJ-00962	AKR1C3 Protein, Human, Recombinant (His) 3-Alpha-HSD Type 2,17-β-Hydroxysteroid Dehydrogenase Type 5,...	Human	HEK293 Cells
	AKR1C3, is an enzyme which belongs to the aldo/keto reductase family. It is expressed in many tissues including adrenal gland, brain, kidney, liver, lung, mammary gland, placenta, small intestine, colon, spleen, prostate and testis. AKR1C3 catalyzes the conversion of aldehydes and ketones to alcohols. It catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2,which functions as a bi-directional 3-alpha-, 17-beta- and ...
TMPJ-00302	Serpin F2 Protein, Mouse, Recombinant (hFc) Alpha-2-PI,α-2-antiplasmin,Alpha-2-AP,α-2-AP,Serpinf2,Alpha-...	Mouse	HEK293 Cells
	Alpha-2-antiplasmin, also called Serpin F2, is a serine protease inhibitor (serpin) responsible for inactivating plasmin, and an important enzyme participates in fibrinolysis and degradation of other proteins. In liver cirrhosis, there is decreased production of alpha 2-antiplasmin, leading to decreased inactivation of plasmin and an increase in fibrinolysis. Serpin F2 is major expressed on liver and kidney. Some other tissues such as muscle, intestine, central nervous system, and placenta also ...
TMPK-00951	CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated FLJ26931,CDH16,LI-cadherin,MGC138218,cadherin-16,Cadherin-17...	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, R...
TMPH-02126	SORBS2 Protein, Human, Recombinant (His) Sorbin and SH3 domain-containing protein 2,Arg-binding prote...	Human	E. coli
	Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder. SORBS2 Pro...
TMPY-03461	GABARAPL2 Protein, Human, Recombinant (His) GATE16,ATG8,ATG8C,GEF-2,GATE-16,GEF2,GABA(A) receptor-associ...	Human	E. coli
	GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and small intestine. GATE-16 is involved in intra-Golgi traffic. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.
TMPJ-00439	BTNL6 Protein, Mouse, Recombinant (His) EG624681,BTNL6,NG13,Butyrophilin-like 6,Gm6519	Mouse	HEK293 Cells
	Butyrophilin-like 6 (BTNL6) is a member of the BTN/MOG Ig-superfamily and functions with BTNL1 as a regulator of immune cell proliferation. The Btnl6 gene is found only in mice. BTNL6 expression is coordinated as a heteromeric protein with BTNL1, and the presence of this complex is correlated with expansion of gamma δ T cells, especially those containing V gamma 7Vδ4 TCR. Btnl6 shows striking sequence similarity to Skint1; is also largely restricted to an epithelial tissue (the small intestine) ...
TMPK-00953	CDH17 Domain 6-7 Protein, Human, Recombinant (mFc) Cdh17,CDH16,MGC138218,BILL-cadherin,HPT-1,cadherin-16,MGC142...	Human	HEK293 Cells
	Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 6-7 Protein, Human, Recombinant (mFc) is expre...
TMPJ-01224	FGFRL1 Protein, Human, Recombinant (His) FGFR5,FGFR-5,FGFRL1,FGFR-Like Protein,FHFR,FGF Homologous Fa...	Human	HEK293 Cells
	Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly exp...
TMPH-00780	CACNA1C Protein, Guinea Pig, Recombinant (His) CACNA1C,CACNL1A1,CACH2,CACN2,Voltage-dependent L-type calciu...	Guinea pig	E. coli
	Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressur...
TMPY-03330	BPHL Protein, Human, Recombinant (His) biphenyl hydrolase-like (serine hydrolase),VACVASE,MCNAA,BPH...	Human	E. coli
	BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir ...
TMPJ-01293	SEMA3C Protein, Human, Recombinant (His) Semaphorin-E,SEMA3C,SEMAE,Semaphorin-3C,Sema E	Human	HEK293 Cells
	Semaphorin 3C is one of six Class 3 secreted semaphorins, which are potent chemorepellents, that play a role in axon and/or vascular guidance during development can be up-regulated in the process of tumor progression. Semaphorin 3C consists of a 20 amino acids signal sequence, a N-terminal Sema domain, a cysteine knot, a furine-type cleavage site, an Ig-like domain, and a C-terminal basic domain. Semaphorin 3C expressed highly in the heart, colon, skeletal muscle, small intestine, testis, ovary ...
TMPJ-00349	RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His) CD265 antigen,FEO,TRANCER,ODFR,ODFROSTS,TRANCE R,TNFRSF11A,O...	Human	HEK293 Cells
	Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutive...
TMPJ-00481	CELA3A Protein, Human, Recombinant (His) Elastase-3A,ELA3A,Elastase IIIA,CELA3A,Chymotrypsin-Like Ela...	Human	HEK293 Cells
	Chymotrypsin-Like Elastase Family Member 3A (CELA3A) is an enzyme that contains one peptidase S1 domain. ELA3A belongs to the peptidase S1 family of the Elastase subfamily. ELA3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. ELA3A may also function in the intestinal transport and metabolism of cholesterol. ELA3A is efficient protease with alanine specificity but only little e...
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重组蛋白

Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPY-05352

Species: Cynomolgus

Expression System: HEK293 Cells

Cadherin 17/CDH17 Protein, Rat, Recombinant (His)

Cat.No: TMPY-02919

Species: Rat

Expression System: HEK293 Cells

Cadherin 17/CDH17 Protein, Human, Recombinant (His)

Cat.No: TMPY-01912

Species: Human

Expression System: HEK293 Cells

Cadherin 17/CDH17 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-06645

Species: Cynomolgus

Expression System: HEK293 Cells

Cadherin 17/CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06324

Species: Human

Expression System: HEK293 Cells

ANXA13 Protein, Human, Recombinant

Cat.No: TMPJ-00590

Species: Human

Expression System: E. coli

ANXA13 Protein, Canine, Recombinant (His)

Cat.No: TMPH-00481

Species: Canine

Expression System: P. pastoris (Yeast)

CDH17 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00583

Species: Human

Expression System: HEK293 Cells

RETNLB Protein, Human, Recombinant (His)

Cat.No: TMPH-02027

Species: Human

Expression System: E. coli

Intrinsic Factor Protein, Human, Recombinant (His)

Cat.No: TMPY-03221

Species: Human

Expression System: HEK293 Cells

CXCL11 Protein, Human, Recombinant

Cat.No: TMPY-03274

Species: Human

Expression System: E. coli

RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)

Cat.No: TMPJ-00662

Species: Human

Expression System: E. coli

Galactosylceramidase Protein, Mouse, Recombinant

Cat.No: TMPH-02667

Species: Mouse

Expression System: E. coli

Zot Protein, Vibrio cholerae serotype O1, Recombinant (His)

Cat.No: TMPH-03703

Species: Vibrio cholerae

Expression System: E. coli

GBA3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01579

Species: Human

Expression System: Baculovirus Insect Cells

FABP6 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00529

Species: Human

Expression System: E. coli

Cytoglobin/CYGB Protein, Human, Recombinant (His)

Cat.No: TMPJ-01248

Species: Human

Expression System: E. coli

B4GALT3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00686

Species: Human

Expression System: HEK293 Cells

REG3G Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00057

Species: Human

Expression System: HEK293 Cells

Mcpt2 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03329

Species: Rat

Expression System: E. coli

ADAMDEC1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00665

Species: Human

Expression System: HEK293 Cells

BTNL4 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00440

Species: Mouse

Expression System: HEK293 Cells

MDH2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00956

Species: Human

Expression System: HEK293 Cells

CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)

Cat.No: TMPK-00952

Species: Human

Expression System: HEK293 Cells

CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00947

Species: Human

Expression System: HEK293 Cells

CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00950

Species: Human

Expression System: HEK293 Cells

CDH17 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01223

Species: Mouse

Expression System: HEK293 Cells

CDH17 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPK-00473

Species: Rhesus

Expression System: HEK293 Cells

XCL1 Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00974

Species: Human

Expression System: HEK293 Cells

CDH17 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00555

Species: Cynomolgus

Expression System: HEK293 Cells

CDH17 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00948

Species: Human

Expression System: HEK293 Cells

CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated

Cat.No: TMPK-01224

Species: Mouse

Expression System: HEK293 Cells

CDH17 Domain 7 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00949

Species: Human

Expression System: HEK293 Cells

RGS5 Protein, Human, Recombinant (His)

Cat.No: TMPY-04058

Species: Human

Expression System: E. coli

CBR3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03867

Species: Human

Expression System: E. coli

EFNA3 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00114

Species: Mouse

Expression System: HEK293 Cells

Apolipoprotein A-V/APOA5 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01087

Species: Mouse

Expression System: E. coli

AKR1C3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00962

Species: Human

Expression System: HEK293 Cells

Serpin F2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00302

Species: Mouse

Expression System: HEK293 Cells

CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

Cat.No: TMPK-00951

Species: Human

Expression System: HEK293 Cells

SORBS2 Protein, Human, Recombinant (His)

Cat.No: TMPH-02126

Species: Human

Expression System: E. coli

GABARAPL2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03461

Species: Human

Expression System: E. coli

BTNL6 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00439

Species: Mouse

Expression System: HEK293 Cells

CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)

Cat.No: TMPK-00953

Species: Human

Expression System: HEK293 Cells

FGFRL1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01224

Species: Human

Expression System: HEK293 Cells

CACNA1C Protein, Guinea Pig, Recombinant (His)

Cat.No: TMPH-00780

Species: Guinea pig

Expression System: E. coli

BPHL Protein, Human, Recombinant (His)

Cat.No: TMPY-03330

Species: Human

Expression System: E. coli

SEMA3C Protein, Human, Recombinant (His)

Cat.No: TMPJ-01293

Species: Human

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)

Cat.No: TMPJ-00349

Species: Human

Expression System: HEK293 Cells

CELA3A Protein, Human, Recombinant (His)

Cat.No: TMPJ-00481

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0109	Bempedoic acid-d4
	Bempedoic acid-d4 是 Bempedoic acid 的氘代化合物。Bempedoic acid 的 CAS 号为 738606-46-7。ETC-1002 是一种 ATP-柠檬酸裂解酶抑制剂，可激活AMPK。它是脂质和碳水化合物代谢的调节剂。
T71055	Albendazole-d7
	Albendazole-d7 is intended for use as an internal standard for the quantification of albendazole by GC- or LC-MS. Albendazole is an orally bioavailable benzimidazole anthelmintic that is active against a variety of helminths, including liver flukes, tapeworms, and roundworms. It eliminates Trichostrongylus in the fourth stomach of cattle and sheep when orally administered at doses ranging from 2.5 to 10 mg/kg as well as other species in the fourth stomach and the small and large intestine. Alben...

同位素标记化合物

Bempedoic acid-d4

Cat.No: TMIH-0109

Cat.No: T71055

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