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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name
L2170 肿瘤免疫治疗小分子化合物库

449 compounds
449 种靶向肿瘤免疫治疗靶点的小分子,可用于高通量和高内涵筛选,是研究肿瘤免疫治疗的有力工具;

化合物库

肿瘤免疫治疗小分子化合物库
Cat.No: L2170
Compounds: 449
Cat. No. Product Name Target Signaling Pathways
T76912 Atorolimumab

Atorolimumab (P3x22914G4) 是一种单克隆抗体,用于靶向程序性死亡-1 (PD-1) 的免疫疗法。
T74508 SS47

Others Others
SS47 是一种基于PROTAC 的HPK1降解剂,可发挥蛋白酶体介导的 HPK1 降解。SS47 降解 HPK1 也显着增强了 BCMA CAR-T 细胞研究的体内抗肿瘤功效。HPK1 是一种免疫抑制调节激酶,是肿瘤免疫疗法的有潜力靶点。

化合物

Atorolimumab
Cat.No: T76912
Synonym:
Target:
SS47
Cat.No: T74508
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T6559 Rhamnose monohydrate

L-鼠李糖,L-(+)-Rhamnose Monohydrate

Others Others
Rhamnose monohydrate (L-(+)-Rhamnose Monohydrate) 是一种存在植物和细菌中的单糖。它能通过胞外途径穿过上皮细胞,可以作为肠吸收的标志。Rhamnose monohydrate 免疫原连接物能被用于免疫疗法。
T5120 Rhamnose

6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose

Calcium Channel; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism
alpha-L-Rhamnose (6-Deoxy-L-mannose) 是存在植物和细菌中的一种单糖。Rhamnose- 免疫原连接物能被用于免疫疗法。Rhamnose 能通过胞外途径穿过上皮细胞,能够作为肠吸收的标志。

天然产物

Rhamnose monohydrate
Cat.No: T6559
Synonym: L-鼠李糖,L-(+)-Rhamnose Monohydrate
Target: Others
Rhamnose
Cat.No: T5120
Synonym: 6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose
Target: Calcium Channel, Endogenous Metabolite
Cat. No. Product Name Species Expression System
TMPK-00492 IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

Igifbp,Interleukin-18-binding protein,IL-18BP

Cynomolgus HEK293 Cells
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice. IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombi...
TMPK-00082 IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated

Igifbp,IL-18BP,IL-18BPA

Human HEK293 Cells
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice. IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated...
TMPK-00491 IL-18BP Protein, Cynomolgus, Recombinant (His)

Igifbp,Interleukin-18-binding protein,IL-18BP

Cynomolgus HEK293 Cells
Cytokines were the first modern immunotherapies to produce durable responses in patients with advanced cancer,components of the interleukin-18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy could enhance anti-tumour immunity. IL-18BP, a high-affinity IL-18 decoy receptor, is frequently upregulated in diverse human and mouse tumours and limits the anti-tumour activity of IL-18 in mice. IL-18BP Protein, Cynomolgus, Recombinant (His) is expressed i...
TMPK-00809 CD37 Protein, Human, Recombinant (His)

Tspan-26,GP52-40,Tetraspanin-26,MGC120234,CD37 molecule,CD37

Human HEK293 Cells
CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and ta...

重组蛋白

IL-18BP Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
Cat.No: TMPK-00492
Species: Cynomolgus
Expression System: HEK293 Cells
IL-18BP Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00082
Species: Human
Expression System: HEK293 Cells
IL-18BP Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00491
Species: Cynomolgus
Expression System: HEK293 Cells
CD37 Protein, Human, Recombinant (His)
Cat.No: TMPK-00809
Species: Human
Expression System: HEK293 Cells
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