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Search Results for " immune-stimulatory "

Targets Recommended: Others Drug-Linker Conjugates for ADC

2

抑制剂 & 化合物

3

天然产物

16

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T82954	ATAC21	Others; Drug-Linker Conjugates for ADC	Antibody-drug Conjugate/ADC Related; Others
	ATAC21是一种连接子免疫刺激化合物，它通过含琥珀酰亚胺基团的稳定型马来酰亚胺-PEG4连接子与免疫刺激化合物结合而成。ATAC21能够与SBT-040（抗CD40抗体）结合，形成具有免疫激活作用的偶联物。
T74870	TMX-201	Others	Others
	TMX-201，一种TLR7配体-磷脂共轭物，表现出显著的免疫刺激活性，适用于乳腺癌与黑色素瘤的研究。

化合物

Cat.No: T82954

Target: Others, Drug-Linker Conjugates for ADC

Cat.No: T74870

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN1686	Ginsenoside Rg4 人参皂苷 RG4	Antibacterial	Microbiology/Virology
	Ginsenoside Rg4 是分离自Panax ginsengC. A. Meyer 叶子中的一种人参三醇型人参皂苷。人参三醇型人参皂苷具有多种生物活性，包括防腐，抗糖尿病，伤口愈合，免疫刺激和抗氧化活性等。
TN2232	Soyasaponin Ab	NOS; NF-κB; COX	Immunology/Inflammation; Neuroscience; NF-κB
	Soyasaponin Ab 是一种大豆皂苷。Soyasaponin Ab 在 3T3-L1 脂肪细胞中通过下调 PPARγ 产生抗肥胖的作用。
T2961	Notoginsenoside R1 Sanqi glucoside R1,Sanchinoside R1,三七皂苷R1	Apoptosis; ERK; Beta Amyloid	Apoptosis; MAPK; Neuroscience
	Notoginsenoside R1 (Sanchinoside R1) 属于皂苷类天然产物，是三七的主要活性单体。Notoginsenoside R1 具有心血管保护、神经保护、肝脏保护、抗肿瘤、免疫调节等活性。

天然产物

Ginsenoside Rg4

Cat.No: TN1686

Synonym: 人参皂苷 RG4

Target: Antibacterial

Cat.No: TN2232

Target: NOS, NF-κB, COX

Notoginsenoside R1

Cat.No: T2961

Synonym: Sanqi glucoside R1,Sanchinoside R1,三七皂苷R1

Target: Apoptosis, ERK, Beta Amyloid

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00280	B7-H6 Protein, Human, Recombinant (His & Avi), Biotinylated NCR3LG1,B7H6,DKFZp686O24166,B7-H6,DKFZp686I21167,B7 Homolog ...	Human	HEK293 Cells
	B7-H6 is a glycosylated member of the B7 family of immune co‑stimulatory proteins. which is a ligand for the NK cell activating receptor NKp30, was targeted to create a CAR that targets multiple tumor types. B7H6 is expressed on various primary human tumors, including leukemia, lymphoma and gastrointestinal stromal tumors, but it is not constitutively expressed on normal tissues.
TMPK-00167	OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi) OX40 homologue,Ly-70,OX40, TXGP1L,OX40L receptor,IMD16,CD134...	Human	HEK293 Cells
	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 23.2 kDa and the acces...
TMPK-00062	CD160 Protein, Human, Recombinant (His & Avi) BY55FLJ46513,NK28,NK1, BY55,CD160	Human	HEK293 Cells
	CD160 (also Natural killer cell receptor BY55) is a 27 ‑ 30 kDa member of the Ig superfamily. In human, it is expressed principally on nonmyeloid hematopoietic cells. CD160 antigenis a receptor on immune cells capable to deliver stimulatory or inhibitory signals that regulate cell activation and differentiation. Exists as a GPI-anchored and as a transmembrane form, each likely initiating distinct signaling pathways via phosphoinositol 3-kinase in activated NK cells and via LCK and CD247/CD3 zeta...
TMPK-00169	OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated IMD16,ACT-135,OX40 homologue,Ly-70, TXGP1L,TNFRSF4,OX40,OX40...	Human	HEK293 Cells
	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular wei...
TMPK-00464	OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi), Biotinylated CD134,TXGP1L,ACT-135,Ly-70,OX40,Txgp1,OX40L receptor,TNFRSF4	Mouse	HEK293 Cells
	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.2 kDa...
TMPJ-00189	TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His) HAVCR2,Tim-3,TIM3,T cell immunoglobulin and mucin domain3	Cynomolgus	HEK293 Cells
	T cell immunoglobulin and mucin domain 3 is a member of the TIM family of immune regulating molecules. Mature cynomolgus TIM3 consists of a 182 amino acid (aa)extracellular domain (ECD), a 21 aa transmembrane segment, and a 78 aa cytoplasmic tail. TIM3 is up-regulated on several populations of activated myeloid cells (macrophage, monocyte, dendritic cell, microglia, mast cell) and T cells (Th1, CD8+, NK, Treg). Its binding to Galectin9 induces a range of immunosuppressive functions which enhance...
TMPK-00596	SECTM1 Protein, Human, Recombinant (hFc) SECTM1,K-12	Human	HEK293 Cells
	SECTM1 is a T/NK cell "co-stimulatory" molecule that is expressed in the peripheral blood by neutrophils and monocytes.Human monocytic cells also displayed a pronounced negative regulation of SECTM1 mRNA expression by LPS, while at the protein level SECTM1 expression was also shown to be regulated by IFN and LPS. This tight regulation of SECTM1 gene expression and rapid upregulation highlights its relevance in the innate immune response.
TMPK-00463	OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi) CD134,OX40 homologue,OX40,IMD16,OX40L receptor, TXGP1L,TNFRS...	Mouse	HEK293 Cells
	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.2 kDa and the acces...
TMPK-00053	GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag) AITRL,TNFSF18,TL6,GITR Ligand,GITRL	Human	HEK293 Cells
	Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecula...
TMPK-01064	GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc) GITRL,GITR Ligand,TL6,TNFSF18,AITRL	Mouse	HEK293 Cells
	Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is ...
TMPK-00054	GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated TL6,GITR Ligand,TNFSF18,AITRL,GITRL	Human	HEK293 Cells
	Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept. GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated is expressed in HEK293 mammalian cells with...
TMPK-00168	OX40/TNFRSF4 Protein, Human, Recombinant (aa 29-216, His & Avi), Biotinylated IMD16,TNFRSF4,CD134,ACT-135, TXGP1L,OX40 homologue,OX40,OX40...	Human	HEK293 Cells
	Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. OX40/TNFRSF4 Protein, Human, Recombinant (aa 29-216, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight ...
TMPJ-00958	B7-1 Protein, Rabbit, Recombinant (His) Activation B7-1 antigen,T-lymphocyte activation antigen CD80...	Rabbit	HEK293 Cells
	Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can ...
TMPJ-00877	IL-2 Protein, Rat, Recombinant (His) 白介素,白细胞介素,IL2,Interleukin-2,TCGF,IL-2,T-cell growth factor,A...	Rat	HEK293 Cells
	Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine...
TMPY-00004	CD28 Protein, Rat, Recombinant (hFc) CD28 molecule	Rat	HEK293 Cells
	CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell r...
TMPJ-00630	B7-1 Protein, Cynomolgus, Recombinant (hFc) B7,CD80,T-lymphocyte activation antigen CD80,Activation B7-1...	Cynomolgus	HEK293 Cells
	Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.CD80 plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the ...

重组蛋白

B7-H6 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00280

Species: Human

Expression System: HEK293 Cells

OX40/TNFRSF4 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00167

Species: Human

Expression System: HEK293 Cells

CD160 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00062

Species: Human

Expression System: HEK293 Cells

OX40/TNFRSF4 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00169

Species: Human

Expression System: HEK293 Cells

OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00464

Species: Mouse

Expression System: HEK293 Cells

TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-00189

Species: Cynomolgus

Expression System: HEK293 Cells

SECTM1 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00596

Species: Human

Expression System: HEK293 Cells

OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi)

Cat.No: TMPK-00463

Species: Mouse

Expression System: HEK293 Cells

GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)

Cat.No: TMPK-00053

Species: Human

Expression System: HEK293 Cells

GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-01064

Species: Mouse

Expression System: HEK293 Cells

GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated

Cat.No: TMPK-00054

Species: Human

Expression System: HEK293 Cells

OX40/TNFRSF4 Protein, Human, Recombinant (aa 29-216, His & Avi), Biotinylated

Cat.No: TMPK-00168

Species: Human

Expression System: HEK293 Cells

B7-1 Protein, Rabbit, Recombinant (His)

Cat.No: TMPJ-00958

Species: Rabbit

Expression System: HEK293 Cells

IL-2 Protein, Rat, Recombinant (His)

Cat.No: TMPJ-00877

Species: Rat

Expression System: HEK293 Cells

CD28 Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-00004

Species: Rat

Expression System: HEK293 Cells

B7-1 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPJ-00630

Species: Cynomolgus

Expression System: HEK293 Cells

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