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Search Results for " hypogonadism "

Targets Recommended: Estrogen Receptor/ERR

抑制剂 & 化合物

天然产物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T7313	Enclomiphene citrate 恩氯米芬柠檬酸盐,Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate	Estrogen Receptor/ERR	Endocrinology/Hormones
	Enclomiphene citrate (trans-Clomiphene citrate) 是口服具有活力的 oestrogen receptor 拮抗剂，具有抗雌激素活性。
T38572	Testosterone buciclate	Others	Others
	Testosterone buciclate, a long-acting androgen ester, shows promise as a research agent for male hypogonadism.
T27826	LGD-2941 LGD 2941,LGD2941	Others	Others
	LGD-2941 is an androgen receptor modulator. LGD-2941 is used for the treatment of hypogonadism, female sexual dysfunction and menopausal syndrome.
TP1094	TAK-448 MVT-602
	TAK-448 (MVT-602) is a potent and full KISS1R agonist with an IC50 of 460 pM and an EC50 of 632 pM.TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.
T74284	SH379	Others	Others
	SH379为2-甲基嘧啶-稠合三环二萜衍生物，是具有口服活性的有效抗迟发性性腺机能减退剂。它显著促进StAR与3β-HSD等关键睾酮合成相关酶的表达，并通过调节AMPK/mTOR信号通路刺激自噬。
T62572	Enclomiphene hydrochloride	Others	Others
	Enclomiphene ((E)-Clomiphene) hydrochloride 是一种口服具有活力的、有效的非甾体雌激素受体 (estrogen receptor) 拮抗剂，具有抗雌激素作用。Enclomiphene hydrochloride 能够用于研究卵巢功能障碍、睾酮缺乏、男性性腺功能减退症和 type 2 型糖尿病。

化合物

Enclomiphene citrate

Cat.No: T7313

Synonym: 恩氯米芬柠檬酸盐,Enclomifene citrate,(E)-Clomiphene citrate,trans-Clomiphene citrate

Target: Estrogen Receptor/ERR

Testosterone buciclate

Synonym: LGD 2941,LGD2941

Enclomiphene hydrochloride

Cat.No: T62572

Synonym:

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TC0025	Testosterone acetate NSC523836,NSC-523836,NSC 523836,醋酸睾酮	Others	Others
	Testosterone acetate (NSC-523836) 是一种 Testosterone 前药，是一种天然存在的雄激素睾酮酯。它可用于阳痿、虚弱、疲劳和性腺机能减退的研究。

天然产物

Testosterone acetate

Cat.No: TC0025

Synonym: NSC523836,NSC-523836,NSC 523836,醋酸睾酮

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01379	TAC3 Protein, Human, Recombinant (His) Neurokinin-B,Tachykinin-3,UNQ585/PRO1155,NKNB,ZNEUROK1,TAC3,...	Human	E. coli
	Tachykinin 3 (TAC3) is a secreted protein that belongs to the Tachykinin family. Tachykinins are active peptides that excite neurons and evoke behavioral responses; they are potent vasodilators and secretagogues, and contract many smooth muscles in pregnancy. TAC3 is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. It is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension ...
TMPY-01635	PCSK1 Protein, Human, Recombinant (His) proprotein convertase subtilisin/kexin type 1,SPC3,PC1,BMIQ1...	Human	HEK293 Cells
	Neuroendocrine convertase 1, also known as Prohormone convertase 1, Proprotein convertase 1, PCSK1 and NEC1, is an enzyme which belongs to the peptidase S8 family and Furin subfamily. PCSK1 is an enzyme that performs the proteolytic cleavage of prohormones to their intermediate (or sometimes completely cleaved) forms. It is present only in neuroendocrine cells such as brain, pituitary and adrenal, and most often cleaves after a pair of basic residues within prohormones but can occasionally cleav...