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Cat. No. | Product Name | ||
---|---|---|---|
L5300 | 线粒体靶向库 | 812 compounds | |
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T25080 |
Amiprilose
SM1213,SM 1213,SM-1213 |
Antibacterial | Microbiology/Virology |
Amiprilose (SM 1213) 具有抗炎活性,抑制多种过度增殖细胞类型的增殖。Amiprilose 诱导淋巴因子诱导的巨噬细胞激活,可用于研究类风湿性关节炎和银屑病。 | |||
T10912 |
S1PR1-MO-1
|
Others | Others |
S1PR-MO-1 is a modulator of sphingosine-1-phosphate receptor and is used to study hyperproliferative inflammatory diseases. | |||
T39390 |
KDM2B-IN-1
KDM2B-IN-1 |
Others | Others |
KDM2B-IN-1 is a potent inhibitor designed specifically to target and inhibit the activity of histone demethylase KDM2B. This compound is ideal for conducting research related to hyperproliferative diseases. | |||
T10687L |
Casein Kinase II Inhibitor IV Hydrochloride
Casein Kinase II Inhibitor IV Hydrochloride (863598-09-8 free base) |
Others | Others |
Casein Kinase II Inhibitor IV Hydrochloride 是一种表皮角质形成细胞分化的小分子诱导剂,可用于机制研究,并具有治疗皮肤过度增生性疾病的研究潜力。 | |||
T72922 |
TNKS1/2-IN-1
|
Others | Others |
TNKS1/2-IN-1是一种针对tankyrase TNKS1/2的高效抑制剂,其pIC50值介于7.1至8.2之间。该化合物主要用于癌症、纤维化及其他高增殖性疾病的研究领域。 | |||
T83457 |
12R-LOX-IN-1
|
Others | Others |
12R-LOX-IN-1(Compound 4a)是一种效能为IC50: 28.25 μM的12R-LOX抑制剂。该化合物能够有效抑制Imiquimod诱导的银屑病角质形成细胞的异常增殖和集落形成能力,同时减少活性氧、Ki67、IL-17A、TNF-α和IL-6的生成,适用于抗银屑病研究。 | |||
T64052 |
PI3K-IN-27
|
Others | Others |
PI3K-IN-27 是 PI3K 的有效抑制剂。PI3K 是脂质信号激酶大家族,在细胞生长、分化、迁移和细胞凋亡等细胞过程中发挥着关键作用。PI3K-IN-27 对癌症和炎症等过度增殖性疾病或免疫和自身免疫性疾病表现出研究潜力。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4558 |
Trioxsalen
三甲沙林,Trimethylpsoralen,Trioxysalen,Trisoralen |
DNA Alkylator/Crosslinker; DHFR | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism |
Trioxsalen (Trioxysalen) 是一种呋喃香豆素和补骨脂素衍生物,与 UV-A 一起用于光疗治疗白癜风和手部湿疹。它是一种光化学 DNA 交联剂,可用于激光激活定位的基因组链间交联可视化。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02117 |
Marapsin Protein, Human, Recombinant (His)
UNQ1884/PRO4327,protease, serine 27,CAPH2,MPN |
Human | HEK293 Cells |
The name "Pancreasin" because it is transcribed strongly in the pancreas. This secreted, tryptic serine protease, also known as Marapsin or PRSS27 (Protease, serine, 27), is a member of the peptidase S1 family. Pancreasin is inhibited by benzamidine and leupeptin but resists several classic inhibitors of trypsin. Marapsin was constitutively expressed in nonkeratinizing stratified squamous epithelia of human esophagus, tonsil, cervix, larynx, and cornea. In fact, marapsin was the second most stro... |