ht-22 cells

Mirodenafil 是一种磷酸二酯酶5（PDE-5）抑制剂，可用于勃起功能紊乱的研究。

Mirodenafil dihydrochloride 是一种磷酸二酯酶5（PDE-5）抑制剂，可作用于勃起功能紊乱的研究。

PDCD4-IN-1是一种 PDCD4抑制剂（Kd ：350 nM），可促进海马神经元细胞 HT-22 中 BDNF 表达。

5-hydroxy-Nω-methyl Tryptamine is a metabolite of serotonin in humans that has also been found in plants. It is an agonist of the 5-HT receptor subtype 5-HT7 (IC50 = 23 pM in a radioligand binding assay). 5-hydroxy-Nω-methyl Tryptamine increases intracellular cyclic AMP production in HEK293 cells expressing 5-HT7 (EC50 = 22 nM). It inhibits serotonin uptake in HEK293 cells expressing human serotonin transporters (IC50 = 490 nM). Elevated levels of urinary 5-hydroxy-Nω-methyl tryptamine have been found in patients with schizophrenia, depression, and epilepsy.

JGB-1-155是一种正变构调节剂 (N-PAMs)，可增强烟酰胺磷酸核糖基转移酶NAMPT的活性，EC50为3.29 μM。JGB-1-155通过上调人单核细胞THP-1中的NAD+水平缓解氧化应激伤害，并减弱HT-22细胞中TNFα诱导的ROS。