11
4
1
3
Cat. No. | Product Name | ||
---|---|---|---|
L7500 | 凝血与抗凝化合物库 | 144 compounds | |
144 个化合物的独特集合,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4502 |
BISMUTH SUBGALLATE
次没食子酸铋,Dermatol Puder,Bismuth Gallate |
Others | Others |
Bismuth subgallate (Dermatol Puder) 是一种止血剂,可作用于凝血因子 XII ,促使凝血级联的激活,改善纤维蛋白凝块的早期形成。 | |||
T19786 |
Hematin
Ferrihemate,Ferriheme hydroxide,Ferriheme,Ferrihemic acid,羟高铁血红素 |
Others | Others |
Hematin (Ferrihemic acid) 是含铁卟啉,可以结合止血蛋白诱导其失活,降低凝血因子的活性以及阻碍纤维蛋白凝块的溶解。它可用于研究急性卟啉症和癌症。 | |||
T9992 |
SphK1&2-IN-1
|
S1P Receptor | GPCR/G Protein |
SphK1&2-IN-1 是一种鞘氨醇激酶抑制剂,具有抗炎、抗肿瘤和止血作用。 | |||
TP1049L |
Ornipressin Acetate(3397-23-7,free)
鸟氨酸加压素,Orpressin,POR-8 |
Others | Others |
Ornipressin Acetate (POR-8) 是一种有效的血管收缩剂、止血剂和肾脏剂。 | |||
T0312 |
Toluidine Blue
氯托洛宁,Blutene chloride |
Others | Others |
Toluidine Blue (Blutene chloride) 是碱性噻嗪异染染料,能够高度亲和酸性组织成分,广泛应用于活体组织的重要染色及特殊染色。 | |||
T0002 |
Ethamsylate
Cyclonamine,Etamsylate,酚磺乙胺,Dicynene,Aglumin |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
Ethamsylate (Dicynene) 通常用作止血药,增加毛细血管内皮阻力和血小板粘附,抑制前列腺素的生物合成和作用。 | |||
T0948 |
Adrenalone hydrochloride
Adrenalone HCl,肾上腺酮盐酸盐,盐酸肾上腺酮 |
Adrenergic Receptor | GPCR/G Protein; Neuroscience |
Adrenalone hydrochloride (Adrenalone HCl) 是一种多巴胺β氧化酶 (dopamine β oxidase) 抑制剂,结构与去甲肾上腺素转运蛋白 (NET) 配体相似,IC50=36.9 μM。它是一种肾上腺素能 (adrenergic) 激动剂,用作局部血管收缩剂和止血剂。 | |||
T3616 |
Carbazochrome
AC-17,Adrenostazin,Cromadrenal,Adona,Adchnon,卡巴克络,Adedolon |
Others; Phospholipase | Metabolism; Others |
Carbazochrome (Adchnon) 是毛细管稳定剂,是抗出血剂,用于研究出血。 | |||
T28128 |
Naftazone
Etioven,C05CX02 |
Others | Others |
Naftazone is a vasoprotectant drug used for hemostasis. Naftazone is shown to accelerate human saphenous vein endothelial cell proliferation in vitro at concentrations which did not alter the hemostatic balance. | |||
T24442 |
Mecrylate
|
Others | Others |
Mecrylate polymerizes in contact with moisture. It is used as a tissue adhesive. It also has higher homologs have hemostatic and antibacterial properties. | |||
T37964 |
Dicresulene diammonium
|
Others | Others |
Dicresulene diammonium is an impurity found in Policresulen, which is an organic acid possessing hemostatic, antimicrobial, and antiviral properties[1][2]. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7106 |
Menaquinone-4
四烯甲萘醌,Vitamin K2,Menaquinone K4 |
Others; Endogenous Metabolite | Metabolism; Others |
Menaquinone-4 (Vitamin K2) 是维生素 K 的一种,用作止血剂,有潜力用于骨质疏松的研究。 | |||
TL0001 |
dencichine
L-Dencichin,ODAP,Dencichin,三七素 |
Others; HIF/HIF Prolyl-Hydroxylase | Chromatin/Epigenetic; Metabolism; Others |
Dencichine (ODAP) 是抑制从三七中分到的非蛋白氨基酸,可抑制 HIF-prolyl hydroxylase-2 的活性。 | |||
T40758 |
Hydrastinine
|
Others | Others |
Hydrastinine, a key alkaloid component found in Hydrastis canadensis (goldenseal), serves as an effective hemostatic agent. | |||
TN7271 |
Lagochiline
|
Others | Others |
Lagochiline,一种二萜类化合物,具备潜在的止血作用。其可从Lagochilus类植物中提取。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00612 |
PSGL-1/CD162 Protein, Mouse, Recombinant (aa 42-307, hFc)
CLA,PSGL1,CD162,PSGL-1 |
Mouse | HEK293 Cells |
P-selectin glycoprotein ligand 1 is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. As such, it plays a critical role in the tethering of these cells to activated platelets or endothelia expressing P-selectin. As cell adhesion molecules, multiple studies have shown that PSGL-1/ P-selectin interaction is required for the normal recruitment of leukocytes during inflammatory reactions, and also participates in hemostatic responses. PSGL-1 ... | |||
TMPH-02832 |
Serpin A5 Protein, Mouse, Recombinant (His)
Protein C inhibitor,Plasminogen activator inhibitor 3,Serpin... |
Mouse | Baculovirus Insect Cells |
Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin comple... | |||
TMPY-02014 |
Coagulation factor VII/F7 Protein, Human, Recombinant (His)
coagulation factor VII (serum prothrombin conversion acceler... |
Human | HEK293 Cells |
Coagulation factor VII, also known as Serum prothrombin conversion accelerator, Factor VII, F7 and FVII, is a member of the peptidase S1 family. Factor VII is one of the central proteins in the coagulation cascade. It is an enzyme of the serine protease class, and Factor VII (FVII) deficiency is the most frequent among rare congenital bleeding disorders. Factor VII contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one peptidase S1 domain. The main role of factor VII is ... |