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Cat. No. | Product Name | Target | Signaling Pathways |
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T36701 |
Phosphoramide mustard (cyclohexanamine)
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Others | Others |
Phosphoramide mustard cyclohexanamine is the major metabolite for Cyclophosphamide , with anticancer activitiy. Phosphoramide mustard cyclohexanamine induces DNA adduct formation in ovarian granulosa cells, induces DNA damage and elicits the ovarian DNA repair response[1][2]. Phosphoramide mustard cyclohexanamine causes cytotoxicity through forming cross-linked DNA adducts which inhibit DNA strand separation during replication[1].Phosphoramide mustard cyclohexanamine destroys rapidly dividing ce... | |||
T84520 |
Palmitic acid calcium
Calcium palmitate |
Others | Others |
Palmitic acid calcium,一种长链饱和脂肪酸,广泛存在于动物和植物中。它能在小鼠颗粒细胞诱导葡萄糖调节蛋白78 (GRP78) 和CCAAT/增强子结合蛋白同源蛋白 (CHOP) 的表达,可用于建立细胞脂肪变性模型。 | |||
T85207 |
1,2-Dipalmitoyl-3-Octanoyl-rac-glycerol
1,2-Palmitin-3-caprylin |
Others | Others |
1,2-Dipalmitoyl-3-Octanoyl-rac-glycerol 是一种三酰基甘油,其结构特征在于 sn-1 和 sn-2 位置上连接有棕榈酸,在 sn-3 位置上连接有辛酸。棕榈酸,一种广泛存在于动植物体中的长链饱和脂肪酸,已知能够在小鼠颗粒细胞中诱导葡萄糖调节蛋白 78 (GRP78) 与 CCAAT/增强子结合蛋白同源蛋白 (CHOP) 的表达。辛酸,作为一种具有微弱腐臭味的油性液体,不仅应用于酯类香料与染料的制备中,还被认为是一种有效的震颤抑制剂。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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T20597 |
Alginic acid
Protanal LF,褐藻酸,Snow acid algin G,Kelacid,Sazzio,Norgine |
Apoptosis; Autophagy; Histamine Receptor | Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Alginic acid (Snow acid algin G) 是一种从褐海藻中提取的天然多糖,具有抗过敏和抗炎活性。 Alginic acid 抑制组胺释放,可用于食品工业。 |
Cat. No. | Product Name | Species | Expression System |
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TMPY-05176 |
AMH Protein, Human, Recombinant (His)
MIS,anti-Mullerian hormone,MIF |
Human | HEK293 Cells |
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and thi... | |||
TMPY-01762 |
IGF2BP-2 Protein, Human, Recombinant (His & GST)
insulin-like growth factor 2 mRNA binding protein 2,IMP-2,VI... |
Human | Baculovirus Insect Cells |
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is a member of the IGF-II mRNA-binding protein (IMP) family. IGF2BP2 is a member of a family of mRNA binding proteins that, collectively, have been shown to bind to several different mRNAs in mammalian cells, including one of the mRNAs encoding insulin-like growth factor-2. Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) is involved in the stimulation of insulin action. IGF2BP2 / IMP2 is expressed in oocytes, granulosa c... | |||
TMPY-00819 |
HAPLN1 Protein, Human, Recombinant (His)
CRTL1,hyaluronan and proteoglycan link protein 1 |
Human | HEK293 Cells |
Hyaluronan (HA) is a high MW glycosaminoglycan significantly involved in the formation and stability of extracellular matrix via its association with specific HA-binding proteins. HAPLN1, also known as CRTL1 (Cartilage Link Protein 1, CLP) and link protein, is a member of the HA-binding protein (hyaladherins) family, and contains a common structural domain of about 100 amino acids that is termed a Link module with two α-helices and two antiparallel β-sheets. HAPLN1/CRTL1 stabilizes the interacti... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T39423 |
Palmitic acid-13C sodium
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Sodium palmitate-13C is the 13C-labeled variant of palmitic acid, a long-chain saturated fatty acid prevalent in animals and plants. This compound has been shown to induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in mouse granulosa cells. | |||
T40980 |
Palmitic acid-13C2
Palmitic acid-13C2 |
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Palmitic acid-13C2 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. | |||
T40141 |
Palmitic acid-13C16 sodium
Palmitic acid-13C16 sodium |
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Palmitic acid-13C16 sodium, a 13C-labeled form of the naturally occurring saturated fatty acid Palmitic acid sodium, is prevalent in animals and plants. This compound can trigger the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in mouse granulosa cells. |