ganoderic

Ganoderic acid D 是高度氧化的四环三萜，是灵芝的主要活性成分，可诱导 HeLa 人宫颈癌细胞凋亡。它上调 SIRT3的蛋白质表达并通过 SIRT3 诱导脱乙酰化的亲环蛋白 D 。它抑制结肠癌细胞的能量重编程，包括结肠癌细胞中的葡萄糖摄取，乳酸、丙酮酸和乙酰辅酶的产生。

Ganoderic acid GS-1 是一种高度氧化的羊毛甾烷型三萜类化合物，具有抗 HIV-1蛋白酶活性，IC50为 58 μM。

Ganoderic acid C6 是醛糖还原酶活性的抑制剂。

Ganoderic acid B 是从灵芝中分离的一种三萜类天然产物。它是端粒酶抑制剂，抑制 Epstein-Barr 病毒抗原的活化。它是 HIV-1 蛋白酶抑制剂。

Deacetyl ganoderic acid F (DeGA F) 是从灵芝 Ganoderma lucidum 中提取的三萜类化合物，在体外和体内对脂多糖（LPS）诱导的炎症有抑制作用。

Ganoderic acid Me是来源于ganoderma lucidum的三萜类化合物。

Ganoderic acid T为ganoderma lucidum中的一种天然化合物。

Ganoderic acid Mk (GA-Mk)为来源于灵芝菌丝的三萜酸类化合物，能有效抑制细胞增殖，并通过线粒体途径诱导HeLa细胞的细胞凋亡(apoptosis)，在宫颈癌研究中具有应用价值。

Ganoderic acid M 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126539。

Ganoderic acid SZ是一种天然产物，其产品编号为 TN4104，CAS号为 865543-37-9。Ganoderic acid SZ可用作对照参考。

Ganoderic acid AM1 treatment for 48 h inhibited the proliferation of HeLa human cervical carcinoma cells with IC(50) values of 19.8+ -0.7 microM.

Ganoderic acid ε, a naturally occurring terpenoid, is extracted from the Fungus Ganoderma lucidum. This compound possesses an ED 50 value of 12.2 μg mL, as demonstrated in its impact on Meth-A tumor cells.

Ganoderic acid I is a natural product from Ganoderma lucidum .

Ganoderic acid H 是一种羊毛脂烷型三萜，提取自灵芝中。它能够抑制转录因子AP-1 和 NF-kappaB 信号，并抑制乳腺癌细胞细胞的生长和入侵。

Ganoderic acid G 分离自灵芝菌管层表面。

Ganoderic acid A 能够抑制 JAK-STAT3信号通路，也能抑制细胞增殖，存活率和 ROS。 它对人骨肉瘤 HOS 和MG-63细胞具有增殖抑制、凋亡和侵袭抑制作用。

Ganoderic acid C1 是分离自 G. lucidum 中的天然产物，能够抑制小鼠巨噬细胞TNF-α 的生成。

The binding affinities of ganoderic acid DM andGanoderic acid ζ (ΔGbind, -16.83 and-10.99 kcal mol-1) are comparable to that of current commercial drug oseltamivir (-23.62 kcal mol-1);Ganoderic acid DM is a potential source of anti-influenza ingredient, with novel binding pattern and advantage over oseltamivir, it has steric hindrance on the 150 cavity of N1 protein, and exerts activities across the H274Y and N294S mutations, is the attractive candidates of novel neuraminidase (NA) inhibitors.Ganoderic acid zeta has cytotoxicity in vitro against Meth-A and LLC cell lines.

Ganoderic acid F 是一种灵芝酸。它具有抗肿瘤和抗转移的活性，与抑制血管生成和涉及细胞增殖和细胞死亡，致癌作用，氧化应激，钙信号传导和内质网应激的蛋白质改变等机制相关。

Ganoderic acid S, a positional isomer of ganoderic acids, can be isolated from the fermented mycelia of Ganoderma lucidum. It can induce apoptosis in HeLa cells through the mitochondria pathway [1].

Ganoderic acid Df 是一种羊毛甾烷型三萜类化合物，可从灵芝的子实体中分离得到。Ganoderic acid Df 有效抑制醛糖还原酶 (aldose reductase)，其 IC50为 22.8 ± 0.6 μM。

Ganoderic acid T1是Ganoderic acid T的去乙酰化衍生物，具有促进癌细胞凋亡(apoptosis)的功能。它通过降低线粒体膜电位以及激活caspase-9和caspase-3来引发细胞凋亡，并增加细胞内ROS的产生，从而表现出促氧化活性和细胞性毒作用，同时减弱抗氧化防御系统。

Ganoderic acid K is an angiotensin-converting enzyme inhibitor. It has anti-tumor, and anti-inflammatory activities.

23-Dihydroganoderic Acid N has anticancer effects.

Ganoderic acid T-Q and TR are two inhibitors of H5N1 and H1N1 NAs.

A novel combination of triterpenoids includes at least ganoderic acid S (GAS), ganoderic acid T (GAT), ganoderic acid Me (GAMe), ganoderic acid R (GAR), and ganodermic acid S (GMAS), the composition is suitable for the treatment or prophylaxis of colon ca

Ganoderic acid GS-2 inhibits the activity of the human immunodeficiency virus-1 (HIV-1) protease.

Methyl Ganoderic acid B, 一种从灵芝中分离得到的三萜类化合物，具有类似神经生长因子的神经元存活促进作用。

23S-hydroxy-11,15-dioxo-ganoderic acid DM is a natural product

Ganoderic acid LM2 exhibits potent enhancement of ConA-induced mice splenocytes proliferation in vitro.

Ganoderic acid L is a natural product from the fruiting body of the fungus Ganoderma lucidum (Reishi).

Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71 replication through blocking EV71 uncoating.

Ganoderic acid TR 是一种从药用灵芝中分离出口来的三萜化合物，是 H5N1 和 H1N1 NAs 抑制剂，具有广谱的抗病毒活性。

Ganoderic acid J, a natural terpenoid extracted from Ganoderma lucidum fungus, exhibits anti-inflammatory properties.

Ganoderic acid D2 is a natural product

Ganoderic acid Z 是一种羊毛甾烷三萜类化合物，可以从灵芝属的蘑菇中分离得到。

Ganoderic acid R为一种高效的抗癌化合物，通过促进肿瘤细胞系的凋亡(apoptosis)机制来抑制其生长。它对多药耐药(MDR)肿瘤细胞系(KB-A-1/Dox)及敏感肿瘤细胞系(KB-A-1)展现出显著的细胞毒性效应。

Ganoderic acid Mf为具有抗肿瘤活性的三萜类化合物，能导致细胞周期在G1期停滞，并在正常细胞与癌细胞中显示高度选择性，通过线粒体介导途径促进细胞凋亡(apoptosis)。

Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendritic cell-specific transmembrane pr

Ganoderic acid F has anti-hepatitis B, anti-inflammatory, and anti-tumor-promoting activities.

Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). It is a potential anticancer drug, inhibits topoisomerases and induces apoptosis of cancer cells.

Ganoderic acid TN是一种天然产物，其产品编号为 TN4106，CAS号为 112430-64-5。Ganoderic acid TN可用作对照参考。

Ganoderic acid C2 是分离自灵芝的一种三萜化合物， 具有潜在的抗肿瘤生物活性，以及抗组胺、抗衰老和细胞毒性作用。它对rat lens aldose reductase 具有很高的抑制活性，IC50为 3.8 µM。

Ganodermic acid S, as a membrane acting agent isolated from the fungus Ganoderma lucidum, exerts multiple effects on human platelet function.

12-Hydroxyganoderic acid D is a natural product