fmoc peg3 c2 nhs ester

Fmoc-PEG3-CH2CH2-NHS ester is a PEG-based linker derived from fluorenylmethoxycarbonyl (Fmoc), which is used as a moiety for the efficient synthesis of PROTACs (proteolysis-targeting chimeras)[1]. This compound offers a practical solution for connecting desired molecules and targeting specific proteins for degradation.

N3-PEG4-C2-NHS ester 是一种不可降解的 ADC linker，含 4 个单元 PEG 可用于合成抗体偶联活性分子 (ADC)。

m-PEG8-NHS ester 是一种含 8 个单元 PEG 的 ADC linker，可用于合成抗体偶联活性分子 (ADC)，可用于修饰蛋白质和多肽。

N3-C4-NHS ester 是一种不可切割的 ADC 接头，用于合成抗体-药物偶联物。

Azido-PEG12-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker，是 E3 连接酶配体-linker 偶联物，可用于合成 PROTAC BCL-XL 降解剂 XZ739。

DBCO-PEG3-NHS ester是一种可降解的 ADC linker，可用于合成抗体偶联活性分子 。

Fmoc-NH-PEG8-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物。它可用于 PROTAC 的合成分子。

Biotin-PEG12-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Mal-amido-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Ald-Ph-NHS ester 是用于抗体-药物偶联的不可切割接头。

Boc-NH-O-C1-NHS ester 是一种属于 alkyl ether 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Tetrazine-Ph-NHCO-C3-NHS ester是一种源于PEG的PROTACs合成连接剂。

Propargyl-C1-NHS ester (4-Pentynoic Acid Succinimidyl Ester) 是一种不可切割的 ADC 接头，可用于合成抗体偶联药物。

Mal-PEG1-NHS ester 是一种可裂解的基于 PEG 的 ADC 接头，用于合成抗体-药物偶联物。它也是基于 PEG 的 PROTAC 接头，可用于 PROTAC 的合成。

Bromo-PEG3-C2-acid 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

DBCO-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) 包含基于 Thalidomide 的 cereblon 配体和 3 个单元的 PEG linker，是一种合成的 E3 连接酶配体-linker 偶联物。

N3-Ph-NHS ester 是一种不可切割的 ADC 接头，用于合成抗体-药物偶联物。

Fmoc-PEG12-NHS ester 是 PEG 类 PROTAC linker。可用于合成 PROTAC 分子。

Boc-NH-PEG3-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Benzyl-PEG3-methyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG3-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Pomalidomide-PEG3-C2-NH2 hydrochloride, also known as Cereblon Ligand-Linker Conjugate 5, is a chemically synthesized E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand based on Pomalidomide and a linker commonly employed in PROTAC technology.

Bis-PEG3-NHS ester 是用于抗体-药物偶联的不可切割的 3 单元 PEG 接头。

Biotin-PEG3-NHS ester 是基于 PEG 结构且可以用来制备 PROTAC 的 PROTAC linker。

Bis-PEG9-NHS ester, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker employed in the synthesis of PROTACs[1].

Phthalimide-PEG3-C2-OTs (Compound 5) is a PROTAC linker composed of PEGs. It is utilized in the synthesis of various PROTACs, which involve the connection of two distinct ligands through a linker. One ligand is specific for an E3 ubiquitin ligase, while the other ligand is designed for targeting the specific protein of interest. Through leveraging the intracellular ubiquitin-proteasome system, PROTACs are capable of selectively degrading target proteins [1].

Cbz-NH-PEG3-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker featuring a terminal azide group. It is commonly employed in the synthesis of PROTACs[1].

Bis-PEG25-NHS ester is a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs) [1].

Ald-Ph-amido-PEG3-C2-Pfp ester is a noncleavable antibody-drug conjugate (ADC) linker that falls under the category of polyethylene glycol (PEG) linkers.

Azido-PEG4-(CH2)3-methyl ester is a polyethylene glycol (PEG) based linker utilized in the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Azido-PEG3-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG3-C2-NH2 is a PEG-based PROTAC linker employed in PROTACs synthesis[1].

Fmoc-PEG5-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-NH-PEG10-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bis-PEG10-NHS ester, a cleavable ADC linker, is utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

PC Mal-NHS carbonate ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. This chemical compound plays a crucial role in facilitating the conjugation of drugs to antibodies, enabling targeted delivery and enhanced efficacy of therapeutic agents. Its unique carbonate ester structure allows for efficient cleavage in the targeted environment, ensuring the controlled release of the drug payload. Its application in ADC synthesis highlights its importance in the development of innovative and targeted cancer therapies.

t-Boc-Aminooxy-PEG4-NHS ester is a polyethylene glycol (PEG) derivative, functioning as a linker for PROTAC synthesis[1].

Acid-PEG3-C2-Boc is a compound used as a linker in the synthesis of PROTACs to facilitate the degradation of EGFR and the inhibition of mTOR[1][2]. It is classified as a PEG- and alkyl ether-based PROTAC linker.

Fmoc-aminooxy-PEG12-NHS ester is a polyethylene glycol (PEG) derivative commonly employed as a PROTAC linker for the synthesis of PROTACs[1].

m-PEG8-CH2CH2-NHS ester is a PEG--based PROTAC linker can be used in the synthesis of PROTACs.

DBCO-NHS ester 2 is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs). It is a Dibenzylcyclooctyne (DBCO) derivative specifically designed for application in copper-free click chemistry [1].

m-PEG25-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-amido-PEG2-C2-NHS ester is a non-cleavable 2-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.