fmoc nh peg5 ch2cooh

Fmoc-NH-PEG5-CH2COOH is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

5-Ethynyl-2'-deoxyuridine 是一种属于 alkyl chain 类的 PROTAC linker，可用于 PROTAC 的合成分子。它是一种胸腺嘧啶核苷类似物，在细胞增殖时能够插入正在复制的 DNA 分子中， EdU 与染料的共轭反应可以进行高效快速的细胞增殖检测分析。

Boc-NH-PEG4-CH2COOH 是一种可切割的 ADC 接头，用作抗体-药物偶联物的接头。它也是基于 PEG 的 PROTAC 接头，可用于 PROTAC 的合成。

Cbz-NH-PEG5-CH2COOH 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Boc-NH-PEG6-CH2COOH 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Boc-NH-PEG3-CH2COOH 是基于 PEG 的 PROTAC linker，用于合成 PROTAC。

Cbz-NH-PEG3-CH2COOH 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Thalidomide-5-NH2-CH2-COOH (compound 114) 是原肌球蛋白受体激酶的选择性抑制剂。它是 E3 连接酶的配体，具有研究一种或多种疾病的潜力。

Cbz-NH-PEG1-CH2COOH 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Cbz-NH-PEG2-CH2COOH 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) 是一种基于 Thalidomide 的 Cereblon 配体，可用于募集 CRBN 蛋白。它能够利用 linker 与靶蛋白配体连接，得到 PROTAC 分子。

Fmoc-NH-PEG8-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Fmoc-NH-PEG12-CH2CH2COOH 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Amine-PEG-CH2COOH (MW 2000) 是一种基于 PEG 的 PROTAC 接头，可用于合成 PROTAC。

Fmoc-NH-PEG10-acid 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Thalidomide-NH-(CH2)2-NH2 TFA 是一种烷基修饰的 Thalidomide，用作 Cereblon 配体以招募 CRBN 蛋白。它是在以 CRBN 为基础设计的 PROTAC 分子合成中的关键中间体，并用于合成针对 SHP2 蛋白的 PROTAC 小分子。

Fmoc-NH-PEG5-C2-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thiol-PEG-CH2COOH (MW 5000) is a Polyethylene glycol (PEG) derived link molecule, commonly utilized in the construction of PROTACs, which are bifunctional compounds designed for targeted protein degradation [1].

NH-bis-PEG5 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

Thalidomide-NH-C10-COOH (compound 6b) is a synthetic E3 ligase ligand-linker conjugate. This compound combines the Thalidomide-based von Hippel-Lindau (VHL) ligand with a linker commonly employed in PROTAC technology. [1]

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized compound, designed as an E3 ligase ligand-linker conjugate, integrating the cereblon ligand derived from Pomalidomide and a linker employed in PROTAC technology. This compound serves to facilitate targeted protein degradation through the modulation of E3 ligase activity, enabling the selective elimination of specific proteins of interest.

Boc-NH-PEG5-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Fmoc-NH-PEG1-CH2COOH is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

Cbz-NH-PEG10-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-NH-PEG5-CH2CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].

Amine-PEG-CH2COOH (MW 3400) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Biotin-PEG5-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amino-PEG5-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker, suitable for synthesizing PROTACs[1].

Fmoc-NH-PEG9-CH2CH2COOH is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

Fmoc-NH-PEG30-CH2CH2COOH is a PEGylation-based PROTAC linker employed for the synthesis of PROTACs[1].

Thalidomide-5-NH-PEG1-NH2 hydrochloride 是基于Thalidomide 的 cereblon 配体，能够募集 CRBN 蛋白。通过 linker 连接靶蛋白配体，可形成 PROTAC 分子，如 THAL-SNS-032。

Boc-NH-PEG1-Ph-O-CH2COOH is a PROTAC linker used for the EED-targeted PROTAC [1].

Fmoc-amino-PEG3-CH2COOH is a polyethylene glycol (PEG)-based linker, primarily employed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Fmoc-NH-ethyl-SS-propionic acid is a cleavable linker compound utilized for the synthesis of antibody-drug conjugates (ADCs)[1].

Boc-NH-PEG-amine (MW 3400) serves as a PEG-based PROTAC linker and finds application in PROTAC synthesis[1].

Fmoc-NH-PEG6-CH2CH2COOH is a cleavable linker commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].

Fmoc-N-bis-PEG3-NH-Boc is a cleavable ADC linker compound consisting of three PEG units, employed in the synthesis of antibody-drug conjugates (ADCs)[1].

Fmoc-N-amido-PEG-CH2COOH (MW 5000), a PEG-based PROTAC linker, is utilized in PROTAC synthesis[1].

Fmoc-NH-PEG1-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for use in PROTAC technology. It consists of the (S,R,S)-AHPC based VHL ligand and a 5-unit PEG linker [1].

Fmoc-NH-pentanoic acid-NHS-SO3Na is a PROTAC linker molecule derived from an alkyl chain. It possesses the ability to facilitate the synthesis of PROTACs[1].

Fmoc-NH-PEG16-CH2CH2COOH is a polyethylene glycol (PEG)-based linker, specifically designed for use in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

m-PEG5-CH2COOH is a non-cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs).

Boc-NH-PEG-amine (MW 5000) is a PEG-based PROTAC linker enabling the synthesis of PROTACs [1].