(3S,5R)-Fluvastatin sodium is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM). Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-
Fluvastatin sodium is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin D6 sodium is deuterium labeled Fluvastatin sodium.
Fluvastatin-d6 Sodium Salt 是 Fluvastatin Sodium Salt 的氘代化合物。Fluvastatin Sodium Salt 的 CAS 号为 93957-55-2。Fluvastatin sodium salt 是羟甲基戊二酰辅酶 A 还原酶的竞争性抑制剂,IC50为 8 nM。它通过依赖 Nrf2 的抗氧化通路保护血管平滑肌细胞免受氧化应激,是一种常用的降胆固醇剂。
(3R,5S)-Fluvastatin, the 3R,5S-isomer of Fluvastatin (XU 62-320 free acid), stands as the inaugural fully synthetic, competitive inhibitor of HMG-CoA reductase, exhibiting an IC50 value of 8 nM. It safeguards vascular smooth muscle cells from oxidative stress by activating the Nrf2-dependent antioxidant pathway.
(3S,5R)-Fluvastatin D6 sodium is the deuterium-labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM).
Fluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct from the fungal derivatives of this therapeutic class.