|
TMPH-01340
|
Filaggrin Protein, Human, Recombinant (His)
Filaggrin,FLG
|
Human
|
P. pastoris (Yeast)
|
|
Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis. Filaggrin Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 26.8 kDa and the accession number is P20930. |
|
TMPH-01379
|
GSN Protein, Human, Recombinant (His)
GSN,Actin-depolymerizing factor,Brevin,AGEL,Gelsolin
|
Human
|
E. coli
|
|
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis. GSN Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.5 kDa and the accession number is P06396. |
|
TMPY-03863
|
CAPG Protein, Human, Recombinant
capping protein (actin filament), gelsolin-like,HEL-S-66,MCP...
|
Human
|
E. coli
|
|
CAPG, also known as actin Regulatory Protein CAPG, is a a member of the gelsolin/villin family. Members of this family are actin-regulatory proteins. CAPG reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, CAPG contributes to the control of actin-based motility in non-muscle cells. CAPG may also play an important role in macrophage function. |
|
TMPH-02251
|
TMOD1 Protein, Human, Recombinant (GST)
Tropomodulin-1,TMOD1,Erythrocyte tropomodulin
|
Human
|
E. coli
|
|
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus. |
|
TMPH-01217
|
DSG3 Protein, Human, Recombinant (E. coli, His)
130 kDa pemphigus vulgaris antigen (PVA),CDHF6,DSG3,Cadherin...
|
Human
|
E. coli
|
|
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
|
TMPH-00623
|
Flagellin Protein, E. coli, Recombinant (His & SUMO)
fliC,Flagellin
|
E. coli
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. |
|
TMPH-01256
|
Dystonin Protein, Human, Recombinant (His & SUMO)
DT,DST,BPAG1,BP240,BP230,KIAA0728,Dystonin,DMH
|
Human
|
E. coli
|
|
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transpo... |
|
TMPH-01257
|
Dystonin Protein, Human, Recombinant (His)
DT,BP230,Dystonin,BP240,DST,DMH,BPAG1,KIAA0728
|
Human
|
P. pastoris (Yeast)
|
|
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transpo... |
|
TMPH-00327
|
Flagellin A Protein, Campylobacter jejuni, Recombinant
flaA,Flagellin A
|
Campylobacter jejuni
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin A Protein, Campylobacter jejuni, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 59.5 kDa and the accession number is Q46113. |
|
TMPH-00624
|
Flagellin Protein, E. coli, Recombinant
fliC,Flagellin
|
E. coli
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin Protein, E. coli, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 51.2 kDa and the accession number is P04949. |
|
TMPY-03392
|
CKAP1/TBCB Protein, Human, Recombinant (His)
CKAPI,tubulin folding cofactor B,CG22,CKAP1
|
Human
|
E. coli
|
|
Tubulin-folding cofactor B, also known as TBCB, belongs to the TBCB family. It contains 1 CAP-Gly domain and can be detected in most tissues. TBCB binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway. The cytoskeleton is composed of 3 structural elements: actin filaments, microtubules, and intermediate filaments. TBCB is involved in regulation of tubulin heterodimer dissociation. It may function as a negative regulator of axonal growth. |
|
TMPH-01219
|
DSP Protein, Human, Recombinant (His)
DSP,Desmoplakin,DP,250/210 kDa paraneoplastic pemphigus anti...
|
Human
|
P. pastoris (Yeast)
|
|
Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. |
|
TMPH-02252
|
TPM3 Protein, Human, Recombinant (GST)
Gamma-tropomyosin,Tropomyosin alpha-3 chain,Tropomyosin-3,TP...
|
Human
|
E. coli
|
|
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. |
|
TMPH-01216
|
DSG1 Protein, Human, Recombinant (His & Myc)
Cadherin family member 4,DGI,Pemphigus foliaceus antigen,CDH...
|
Human
|
E. coli
|
|
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
|
TMPH-03504
|
Flagellin C Protein, Shigella flexneri, Recombinant (His)
fliC,Flagellin
|
Shigella flexneri
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin C Protein, Shigella flexneri, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 62.1 kDa and the accession number is Q08860. |
|
TMPH-03212
|
TPM1 Protein, Rabbit, Recombinant (His & Myc)
TPM1,Alpha-tropomyosin,Tropomyosin alpha-1 chain,Tropomyosin...
|
Rabbit
|
Baculovirus Insect Cells
|
|
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. TPM1 Protein, Rabbit, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 3... |
|
TMPH-01320
|
CAPZA2 Protein, Human, Recombinant (His & SUMO)
CAPZA2,CapZ alpha-2,F-actin-capping protein subunit alpha-2
|
Human
|
E. coli
|
|
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CAPZA2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 48.8 kDa and the accession number is P47755. |
|
TMPH-02253
|
TPM2 Protein, Human, Recombinant (His)
TPM2,Tropomyosin-2,Tropomyosin beta chain,Beta-tropomyosin
|
Human
|
E. coli
|
|
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization. |
|
TMPH-03213
|
TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc)
Tropomyosin alpha-1 chain,TPM1,Alpha-tropomyosin,Tropomyosin...
|
Rabbit
|
E. coli
|
|
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. TPM1 Protein, Rabbit, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular w... |
|
TMPH-00328
|
Flagellin B(flaB) Protein, Campylobacter jejuni, Recombinant (His)
flaB,Flagellin B
|
Campylobacter jejuni
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin B(flaB) Protein, Campylobacter jejuni, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 61.6 kDa and the accession number is Q46114. |
|
TMPY-02499
|
Cofilin 2 Protein, Human, Recombinant (His)
cofilin 2 (muscle),NEM7
|
Human
|
E. coli
|
|
Cofilin 2 (muscle), also known as CFL2, is a member of cofilin family of the actin-binding protein superfamily. Cofilin2 shows significant homology to the other two members: cofilin 1 and DSTN, through its entire sequence, and contains residues conserved among the cofilin family that are responsible for actin-binding. Cofilin 2 (CFL2) is an important regulator of striated myocyte function. Purified cofilin 2 depolymerized actin filaments in a dose- and pH-dependent manner and reduced the apparen... |
|
TMPH-00326
|
Flagellin A Protein, Campylobacter jejuni, Recombinant (His)
Flagellin A,flaA
|
Campylobacter jejuni
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin A Protein, Campylobacter jejuni, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 61.5 kDa and the accession number is Q46113. |
|
TMPH-01218
|
DSP Protein, Human, Recombinant (His & SUMO)
Desmoplakin,DSP,DP,250/210 kDa paraneoplastic pemphigus anti...
|
Human
|
E. coli
|
|
Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. DSP Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 42.1 kDa and the accession number is P15924. |
|
TMPH-02624
|
Dsg1a Protein, Mouse, Recombinant (His & Myc & SUMO)
Desmoglein-1,DGI,Dsg1a,Dsg1,Desmosomal glycoprotein I,Dsg1-a...
|
Mouse
|
E. coli
|
|
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Dsg1a Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 77.2 kDa and the accession number is Q61495. |
|
TMPH-01672
|
Human metapneumovirus (strain CAN97-83) Matrix protein (His & Myc)
M,Matrix protein,M protein
|
HMPV
|
E. coli
|
|
Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the action of host CRM1 to associate with inclusion bodies, the site of viral transcription and replication. During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer. |
|
TMPH-01730
|
MYBPC3 Protein, Human, Recombinant (His & SUMO)
C-protein, cardiac muscle isoform,Myosin-binding protein C, ...
|
Human
|
E. coli
|
|
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. MYBPC3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 50.8 kDa and the accession number is Q14896. |
|
TMPH-03477
|
Phase 2 flagellin Protein, Salmonella typhimurium, Recombinant (Avi & His & MBP), Biotinylated
fljB,Phase 2 flagellin
|
Salmonella typhimurium
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Phase 2 flagellin Protein, Salmonella typhimurium, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The predicted molecular weight is 79.8 kDa and the accession number is P52616. |
|
TMPJ-00495
|
ISG15 Protein, Human, Recombinant (His)
ISG15,Ubiquitin Cross-Reactive Protein,G1P2,Interferon-Induc...
|
Human
|
E. coli
|
|
Ubiquitin-Like Protein ISG15 (ISG15) is a ubiquitin-like protein that becomes conjugated to many cellular proteins upon activation by interferon-alpha and -beta. Several functions have been ascribed to the encoded protein, including chemotactic activity towards neutrophils, direction of ligated target proteins to intermediate filaments, cell-to-cell signaling, and antiviral activity during viral infections. While conjugates of this protein have been found to be noncovalently attached to intermed... |
|
TMPH-00643
|
K99 fimbrial Protein, E. coli, Recombinant
fanC,K99 fimbrial protein
|
E. coli
|
E. coli
|
|
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.; FanC is the main component of the K99 fimbriae. |
|
TMPH-00748
|
FimA Protein, E. coli, Recombinant (His & SUMO)
fimA,Type-1 fimbrial protein, A chain,Type-1A pilin
|
E. coli
|
E. coli
|
|
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs. FimA Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 31.8 kDa and the accession number is P04128. |
|
TMPH-02244
|
Trichohyalin Protein, Human, Recombinant (His & Myc)
TCHH,Trichohyalin
|
Human
|
E. coli
|
|
Intermediate filament-associated protein that associates in regular arrays with keratin intermediate filaments (KIF) of the inner root sheath cells of the hair follicle and the granular layer of the epidermis. It later becomes cross-linked to KIF by isodipeptide bonds. It may serve as scaffold protein, together with involucrin, in the organization of the cell envelope or even anchor the cell envelope to the KIF network. It may be involved in its own calcium-dependent postsynthetic processing dur... |
|
TMPH-00620
|
F41 fimbrial Protein, E. coli, Recombinant (His & Myc)
Adhesin F41,F41 fimbrial protein,FimF41a
|
E. coli
|
E. coli
|
|
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs. F41 fimbrial Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.4 kDa and the accession number is P11900. |
|
TMPH-01673
|
Human metapneumovirus (strain CAN97-83) Matrix protein (His)
M,Matrix protein,M protein
|
HMPV
|
P. pastoris (Yeast)
|
|
Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the action of host CRM1 to associate with inclusion bodies, the site of viral transcription and replication. During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer. |
|
TMPH-02313
|
RPGR Protein, Human, Recombinant (hFc)
RPGR,X-linked retinitis pigmentosa GTPase regulator
|
Human
|
HEK293 Cells
|
|
Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes. May be involved in microtubule organization and regulation of transport in primary cilia. |
|
TMPH-00619
|
F17 fimbrial Protein, E. coli, Recombinant (His & SUMO)
F17 fimbrial protein,F17a-A,F17 fimbrial adhesive antigen,F1...
|
E. coli
|
E. coli
|
|
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs. F17 fimbrial Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 32.4 kDa and the accession number is P11312. |
|
TMPH-02971
|
Vimentin Protein, Mouse, Recombinant (His & Myc)
Vim,Vimentin
|
Mouse
|
HEK293 Cells
|
|
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.; Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. Vimentin Protein, Mouse, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 58.6 kDa and the accession number i... |
|
TMPH-01752
|
Nestin/NES Protein, Human, Recombinant (His)
Nestin,NES
|
Human
|
P. pastoris (Yeast)
|
|
Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. Nestin/NES Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 2... |
|
TMPH-01731
|
MYBPC2 Protein, Human, Recombinant (His)
C-protein, skeletal muscle fast isoform,Myosin-binding prote...
|
Human
|
E. coli
|
|
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. MYBPC2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.5 kDa and the accession number is Q14324. |
|
TMPH-00642
|
K99 fimbrial Protein, E. coli, Recombinant (His & SUMO)
fanC,K99 fimbrial protein
|
E. coli
|
E. coli
|
|
Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs.; FanC is the main component of the K99 fimbriae. K99 fimbrial Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 32.5 kDa and the accession number is P18103. |
|
TMPH-03415
|
Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc)
Non-structural protein S,NSS
|
RVFV
|
E. coli
|
|
Plays a role in the escape of host innate immune response by promoting the degradation of host EIF2AK2/PKR and inhibiting host transcription. Cytoplasmic NSs interacts with host FBXW11 to degrade PKR whereas nuclear pool binds to host FBXO3 to target TFIIH subunit GTF2H1 for proteasomal degradation. Forms filaments in the nucleus that may sequester NSs binding partners, causing cell cycle arrest. Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc) is expressed... |
|
TMPH-02970
|
Vimentin Protein, Mouse, Recombinant (E. coli, His & Myc)
Vimentin,Vim
|
Mouse
|
E. coli
|
|
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.; Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. Vimentin Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 61.0 kDa and the access... |
|
TMPH-00286
|
Myotrophin Protein, Bovine, Recombinant (His)
MTPN,Myotrophin
|
Bovine
|
P. pastoris (Yeast)
|
|
Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Myotrophin Protein, Bovine, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is... |
|
TMPY-02551
|
CCDC134 Protein, Human, Recombinant (His)
coiled-coil domain containing 134
|
Human
|
HEK293 Cells
|
|
Coiled-coil domain containing 134 (CCDC134) is a 229 amino acids secretory protein. Coiled-coil domain is a motif in which alpha-helix are coiled together. It has been found in many types of proteins, including transcription factors, intermediate filaments and certain tRNA synthetases. Many proteins containing such motif CCDC134 are involved in important biological functions. CCDC134 is also considered as a novel human MAPK-regulating protein that can inhibit the MAPK pathway. This protein signi... |
|
TMPJ-00790
|
GSN Protein, Human, Recombinant (mFc)
ADF,Actin-depolymerizing factor,Brevin,Gelsolin,GSN,AGEL
|
Human
|
HEK293 Cells
|
|
Gelsolin is a calcium-activated actin filament severing and capping protein found in many cell types and as a secreted form in the plasma of vertebrates. Gelsolin is composed of six of these domains, termed G1-6. Some reaseraches show that gelsolin can act as a transcriptional cofactor in signal transduction and its own expression and function can be influenced by epigenetic changes. The difference in the expression levels of cytoplasmic and plasma gelsolin suggests that these two different form... |
|
TMPY-03600
|
TPM4 Protein, Human, Recombinant (His)
tropomyosin 4,HEL-S-108,TPM4
|
Human
|
HEK293 Cells
|
|
TPM4, also known as tropomyosin 4, is a member of the tropomyosin family. Members of this family are actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM4 is expressed in cardiac tissue and platelets. It is highly expressed in the platelets of hypertensive patients. TPM4 plays a central role, in association with the troponin complex, in the calcium-dependent regulation of vertebrate striated muscle contraction. Smo... |
|
TMPY-03984
|
TPM1 Protein, Human, Recombinant (His)
TMSA,tropomyosin 1 (alpha),LVNC9,CMH3,HTM-alpha,CMD1Y,C15orf...
|
Human
|
E. coli
|
|
TPM1, also known as tropomyosin-1, is a member of the tropomyosin family. Members of this family are highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. TPM1 is one type of alpha-helical chain that forms the predomin... |
|
TMPY-03607
|
Cofilin Protein, Human, Recombinant (His)
CFL,HEL-S-15,cofilin 1 (non-muscle)
|
Human
|
E. coli
|
|
CFL1, also known as n-cofilin, is a member of the ADF/Cofilin family. This family comprises three genes: CFL1, CFL2 and DSTN (destrin). ADF/Cofilin family members bind G-actin monomers and depolymerize actin filaments through two mechanisms: severing and increasing the off-rate for actin monomers from the pointed end. Cofilin also binds with other proteins such as myosin, tropomyosin, α-actinin, gelsolin and scruin. These proteins compete with cofilin for actin binding. Сofilin also plays a... |
|
TMPJ-00044
|
TNNC1 Protein, Human, Recombinant (His)
TNNC1,Troponin I,CMH7,TNNI3
|
Human
|
E. coli
|
|
Troponin I, also known as TNI, is a 24 kDa component of a protein complex on striated muscle thin filaments.Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. Troponin I inhibits the calcium-dependent muscle contraction mediated by Troponins... |
|
TMPY-02129
|
Transglutaminase 3/TGM3 Protein, Human, Recombinant (His)
transglutaminase 3,UHS2,TGE
|
Human
|
Baculovirus Insect Cells
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Transglutaminases (TGase) are a family of calcium-dependent acyl-transfer enzymes ubiquitously expressed in mammalian cells and responsible for catalyzing covalent cross-links between proteins or peptides. Transglutaminase 3 (TGM3) is a member of a family of Ca2+-dependent enzymes that catalyze covalent cross-linking reactions between proteins or peptides. TGM3 isoform is widely expressed and is important for epithelial barrier formation. It is a zymogen, requiring proteolysis for activity. Calc... |
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TMPJ-00684
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SNCA Protein, Mouse, Recombinant (His)
Snca,Non-A β component of AD amyloid,Non-A4 component of amy...
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Mouse
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E. coli
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Alpha-synuclein (Snca) belongs to a family of proteins including a-, b-, and g-synucleins. Alpha-synuclein has been found to be implicated in the pathophysiology of many neurodegenerative diseases, including Parkinson's disease (PD) and Alzheimer's disease. Manyneurodegenerative diseases has shown that alpha-synuclein accumulates in dystrophic neurites and in Lewy bodies. The function of alpha-synuclein is closely correlated with its three-dimensional structure, especially for proteins important... |
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