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12

抑制剂 & 化合物

27

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
TP1519 Amylin (IAPP), feline

Amylin (IAPP), feline is the peptide subunit of amyloid found in pancreatic islets of type 2 diabetic patients and in insulinomas.
T76028 Amylin (IAPP), feline TFA

Amylin (IAPP), feline TFA,一种来自猫科动物、含37个氨基酸的多肽,为胰岛β细胞的主要分泌物之一。作为调节肽,它能够抑制胰岛素和胰高血糖素的分泌。
T7222 GS-441524

GS 441524 triphosphate

Others; SARS-CoV; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
GS-441524 是 Remdesivir 的主要活性代谢物,活性更优于 Remdesivir ,治疗患有自然发生的猫传染性腹膜炎的猫。
T0863 Idoxuridine

IDU,碘苷,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid

Antifection; HSV Microbiology/Virology
Idoxuridine (Dendrid) 是一种抑制病毒 DNA 合成的脱氧尿苷类似物,用作抗病毒剂。
T9617 RdRP-IN-2

SARS-CoV Microbiology/Virology
RdRP-IN-2 是一种依赖于 RNA 的 RNA 聚合酶 (RdRp) 抑制剂。它显著抑制 SARS-CoV-2 RdRp,IC50 为 41.2 µM。它还抑制猫冠状病毒 (FIPV) 复制。
T69657 GS-441524 HCl

Others Others
GS-441524 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an EC50 of 0.78 μM.. GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. GS-441524 is a molecular precursor to a pharmacologically active nucleoside triphosphate molecule. These analogs act as an alternative substrate and RNA-chain terminator of viral RNA dependent RNA polymerase. GS-441524 was non-toxic in feline cells at concentrations ...
T61492 Idoxuridine hydrate

Others Others
Idoxuridine hydrate (5-Iodo-2′-deoxyuridine, 5-IUdR, IdUrd) is a competitive inhibitor of phosphorylases. As an iodinated thymidine analogue, it effectively inhibits DNA polymerase and hinders viral replication, making it useful in the treatment of viral eye infections such as herpes simplex keratitis. Against feline herpesvirus, Idoxuridine has been found to have an IC50 value of 4.3 μM [1].
T80602 Dovanvetmab

ZTS-00521505

Dovanvetmab (ZTS-00521505),一种IgG1-κ型抗体,专一性靶向Felcat IL31,由CHO(Chinese Hamster Ovary)细胞主要表达。
T35930 Ganglioside GM2 Mixture (sodium salt)

Others Others
Ganglioside GM2 is a glycosphingolipid component of cellular membranes, primarily the plasma membrane. Levels of ganglioside GM2 are elevated in the brain of patients with Sandhoff disease, as well as feline and mouse models of the disease. Ganglioside GM2 accumulates in the lysosomes of individuals with Tay-Sachs disease and GM2-activator deficiency, as well as in the CNS of patients with and animal models of mucopolysaccharide storage disorders and Niemann-Pick disease types A, C1, and C2. Gan...
T70070 Cisapride tartrate

Others Others
Cisapride tartrate is chemically related to metoclopramide, but unlike metoclopramide, it does not cross the blood-brain barrier or have antidopaminergic effects. Cisapride is a serotonin-4 (5-HT4) receptor agonist. Cisapride was indicated for the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease. The Food and Drug Administration (FDA) in America stopped the marketing of cisapride as of 14th July 2000. They had received at least 341 reports o...
T5539 GS-443902

瑞德西韦代谢物

Nucleoside Antimetabolite/Analog; HCV Protease; SARS-CoV; DNA/RNA Synthesis; RSV; Drug Metabolite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology; Proteases/Proteasome
Remdesivir triphosphate 是一种有效的病毒 RNA 依赖的 RNA 聚合酶抑制剂,对RSVRdRp 和 HCVRdRp 的IC50分别为 1.1 µM 和 5 µM。它是 Remdesivir 的活性三磷酸代谢物。
T60488 Ganciclovir hydrate

Others Others
Ganciclovir (BW 759) hydrate 是一种核苷类似物,是具有口服活性的抗病毒剂,显示出抗巨细胞病毒活性。Ganciclovir hydrate 对疱疹病毒和其他一些 DNA 病毒也具有体外抗病毒活性。Ganciclovir hydrate 在体外抑制人类疱疹病毒 (HSV 1 型和 2 型,CMV) 和腺病毒血清型1、2、4、6、8、10、19、22 和 28 的复制。Ganciclovir hydrate 对猫疱疹病毒 1 型 (FHV-1) 的 IC50为 5.2 μM,可扩散到大脑。

化合物

Amylin (IAPP), feline
Cat.No: TP1519
Synonym:
Target:
Amylin (IAPP), feline TFA
Cat.No: T76028
Synonym:
Target:
GS-441524
Cat.No: T7222
Synonym: GS 441524 triphosphate
Target: Others, SARS-CoV, DNA/RNA Synthesis
Idoxuridine
Cat.No: T0863
Synonym: IDU,碘苷,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid
Target: Antifection, HSV
RdRP-IN-2
Cat.No: T9617
Synonym:
Target: SARS-CoV
GS-441524 HCl
Cat.No: T69657
Synonym:
Target: Others
Idoxuridine hydrate
Cat.No: T61492
Synonym:
Target: Others
Dovanvetmab
Cat.No: T80602
Synonym: ZTS-00521505
Target:
Ganglioside GM2 Mixture (sodium salt)
Cat.No: T35930
Synonym:
Target: Others
Cisapride tartrate
Cat.No: T70070
Synonym:
Target: Others
GS-443902
Cat.No: T5539
Synonym: 瑞德西韦代谢物
Target: Nucleoside Antimetabolite/Analog, HCV Protease, SARS-CoV, DNA/RNA Synthesis, RSV, Drug Metabolite
Ganciclovir hydrate
Cat.No: T60488
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-05655 c-Kit Protein, Rhesus, Recombinant (hFc)

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncoge...

Rhesus HEK293 Cells
c-Kit Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.3 kDa and the accession number is A0A8J8YKB5.
TMPY-04051 c-Kit Protein, Human, Recombinant (hFc)

SCFR,v-kit Hardy-Zuckerman 4 feline sarcoma viral o...

Human HEK293 Cells
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is P10721-2.
TMPY-01935 c-Kit Protein, Human, Recombinant (His)

PBT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma vi...

Human HEK293 Cells
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
TMPH-00350 Adiponectin Protein, Feline, Recombinant

apM-1,30 kDa adipocyte complement-related protein,APM1,ACRP3...

Feline E. coli
Adiponectin Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 24.9 kDa and the accession number is A4PB30.
TMPH-00352 CKM Protein, Feline, Recombinant

M-CK,Creatine kinase M-type,Creatine phosphokinase M-type,CK...

Feline E. coli
CKM Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27.9 kDa and the accession number is M3VYX8.
TMPY-01802 c-Kit Protein, Mouse, Recombinant (His)

SCO5,SCO1,Bs,Gsfsco1,v-kit Hardy-Zuckerman 4 feline...

Mouse HEK293 Cells
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57 kDa and the accession number is P05532-1.
TMPY-06524 EGFR Protein, Feline, Recombinant (His)

epidermal growth factor receptor

Feline Baculovirus Insect Cells
EGFR Protein, Feline, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 70.18 kDa and the accession number is A0A337S424.
TMPH-00353 GDF8 Protein, Feline, Recombinant

Myostatin,MSTN,Growth/differentiation factor 8

Feline E. coli
GDF-8 Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 40.7 kDa and the accession number is M3WPT7.
TMPY-06493 EGF Protein, Feline, Recombinant (hFc)

表皮生长因子,epidermal growth factor

Feline HEK293 Cells
EGF Protein, Feline, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.63 kDa and the accession number is NP_001009381.1.
TMPY-00525 IL-10 Protein, Feline, Recombinant

interleukin 10

Feline E. coli
IL-10 Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.9 kDa and the accession number is P55029.2.
TMPH-00356 PAI-1 Protein, Feline, Recombinant

PAI-1,Endothelial plasminogen activator inhibitor,Serpin E1,...

Feline E. coli
PAI-1 Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 29.7 kDa and the accession number is A9NJ78.
TMPH-00354 CSF1R Protein, Feline, Recombinant (His & SUMO)

FMS,M-CSF-R,CSF-1-R,CSF1R,Proto-oncogene c-Fms,CSF-1R,CD115,...

Feline E. coli
CSF1R Protein, Feline, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 70.8 kDa and the accession number is P13369.
TMPH-00357 SAA1 Protein, Feline, Recombinant (His)

Serum amyloid A protein,SAA1

Feline P. pastoris (Yeast)
Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Feline, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 12.1 kDa and the accession number is P19707.
TMPY-03034 c-Kit Protein, Rat, Recombinant (hFc)

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncoge...

Rat HEK293 Cells
c-Kit Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.4 kDa and the accession number is Q63116.
TMPY-03136 c-Kit Protein, Rat, Recombinant (His)

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncoge...

Rat HEK293 Cells
c-Kit Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.9 kDa and the accession number is Q63116.
TMPY-06652 c-Kit Protein, Rhesus, Recombinant (His)

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncoge...

Rhesus HEK293 Cells
c-Kit Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57 kDa and the accession number is NP_001253024.1.
TMPH-00358 SAA1 Protein, Feline, Recombinant (B2M & His)

Serum amyloid A protein,SAA1

Feline E. coli
Major acute phase reactant. Apolipoprotein of the HDL complex. SAA1 Protein, Feline, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 24.1 kDa and the accession number is P19707.
TMPH-00351 Fel d 4 Protein, Feline, Recombinant (His & SUMO)

Allergen Fel d 4

Feline E. coli
May be a pheromone carrier. Acts as a kairomone, detected by the prey vomeronasal organ and inducing fear reactions in mice. Fel d 4 Protein, Feline, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.7 kDa and the accession number is Q5VFH6.
TMPY-02397 IL-1 beta/IL-1F2 Protein, Feline, Recombinant

interleukin 1, beta,白细胞介素,白介素,interleukin 1, β,IL-1 β

Feline E. coli
IL-1 beta/IL-1F2 Protein, Feline, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is P41687.
TMPY-03567 c-Kit Protein, Human, Recombinant (aa 50-190, His)

SCFR,PBT,C-Kit,CD117,v-kit Hardy-Zuckerman 4 feline...

Human E. coli
c-Kit Protein, Human, Recombinant (aa 50-190, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.9 kDa and the accession number is P10721-1.
TMPY-04564 c-Kit Protein, Human, Recombinant (aa 540-972, His & GST)

C-Kit,PBT,SCFR,CD117,v-kit Hardy-Zuckerman 4 feline...

Human Baculovirus Insect Cells
c-Kit Protein, Human, Recombinant (aa 540-972, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 76.8 kDa and the accession number is P10721-2.
TMPY-06656 c-Kit Protein, Human, Recombinant (His & Avi), Biotinylated

CD117,SCFR,C-Kit,v-kit Hardy-Zuckerman 4 feline sar...

Human HEK293 Cells
c-Kit Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 58.50 kDa and the accession number is P10721-2.
TMPH-00355 Major allergen I polypeptide chain 1 Protein, Feline, Recombinant (His & Myc)

Allergen Cat-1,Allergen Fel d I-A,AG4,Major allergen I polyp...

Feline E. coli
Major allergen I polypeptide chain 1 Protein, Feline, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 15.3 kDa and the accession number is P30438.
TMPY-01801 c-Kit Protein, Mouse, Recombinant (hFc)

SCO1,Gsfsco1,W,v-kit Hardy-Zuckerman 4 feline sarco...

Mouse HEK293 Cells
c-Kit Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.5 kDa and the accession number is P05532-1.
TMPJ-00402 CD117 Protein, Human, Recombinant (hFc)

KIT,CD117,v-kit Hardy-Zuckerman 4 feline sarcoma vi...

Human HEK293 Cells
C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily and CSF-1/PDGF receptor subfamily. SCF R expression on mast cells enables them to infiltrate SCF-secreting tumors where they promote tumor growth and induce local immune suppression. SCF R is up-regulated on dendritic cells by Th2-orTh17-biasing sti...
TMPJ-00038 IL-7 Protein, Mouse, Recombinant (His)

interleukin-7,白介素,IL-7,IL-7 interleukin-7,PBGF,Lymphopoietin...

Mouse HEK293 Cells
Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 and 58-60% with human, equine, bovine, ovine, porcine, feline and canine IL-7. It is widely expressed in primary and secondary lymphoid tissues cell and stromal epithelial cells of the thymus, bone marrow, and intestines. IL-7 activation of IL-7 R alpha is critical for both T cell...
TMPY-04421 FES Protein, Human, Recombinant (His & GST)

FPS,FES proto-oncogene, tyrosine kinase

Human Baculovirus Insect Cells
Proto-oncogene tyrosine-protein kinase Fes/Fps, also known as Proto-oncogene c-Fes, Proto-oncogene c-Fps, Feline sarcoma oncogene, FES and FPS, is a protein which contains oneFCH domain, oneprotein kinase domain and oneSH2 domain. FES is a non-receptor protein tyrosine kinase expressed in hematopoietic progenitors and differentiated myeloid cells. FES is observed in the nuclear, granular and plasma membrane fractions of primary human neutrophils and the myeloid leukemia cell line, HL-6. T...

重组蛋白

c-Kit Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-05655
Species: Rhesus
Expression System: HEK293 Cells
c-Kit Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04051
Species: Human
Expression System: HEK293 Cells
c-Kit Protein, Human, Recombinant (His)
Cat.No: TMPY-01935
Species: Human
Expression System: HEK293 Cells
Adiponectin Protein, Feline, Recombinant
Cat.No: TMPH-00350
Species: Feline
Expression System: E. coli
CKM Protein, Feline, Recombinant
Cat.No: TMPH-00352
Species: Feline
Expression System: E. coli
c-Kit Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01802
Species: Mouse
Expression System: HEK293 Cells
EGFR Protein, Feline, Recombinant (His)
Cat.No: TMPY-06524
Species: Feline
Expression System: Baculovirus Insect Cells
GDF8 Protein, Feline, Recombinant
Cat.No: TMPH-00353
Species: Feline
Expression System: E. coli
EGF Protein, Feline, Recombinant (hFc)
Cat.No: TMPY-06493
Species: Feline
Expression System: HEK293 Cells
IL-10 Protein, Feline, Recombinant
Cat.No: TMPY-00525
Species: Feline
Expression System: E. coli
PAI-1 Protein, Feline, Recombinant
Cat.No: TMPH-00356
Species: Feline
Expression System: E. coli
CSF1R Protein, Feline, Recombinant (His & SUMO)
Cat.No: TMPH-00354
Species: Feline
Expression System: E. coli
SAA1 Protein, Feline, Recombinant (His)
Cat.No: TMPH-00357
Species: Feline
Expression System: P. pastoris (Yeast)
c-Kit Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03034
Species: Rat
Expression System: HEK293 Cells
c-Kit Protein, Rat, Recombinant (His)
Cat.No: TMPY-03136
Species: Rat
Expression System: HEK293 Cells
c-Kit Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-06652
Species: Rhesus
Expression System: HEK293 Cells
SAA1 Protein, Feline, Recombinant (B2M & His)
Cat.No: TMPH-00358
Species: Feline
Expression System: E. coli
Fel d 4 Protein, Feline, Recombinant (His & SUMO)
Cat.No: TMPH-00351
Species: Feline
Expression System: E. coli
IL-1 beta/IL-1F2 Protein, Feline, Recombinant
Cat.No: TMPY-02397
Species: Feline
Expression System: E. coli
c-Kit Protein, Human, Recombinant (aa 50-190, His)
Cat.No: TMPY-03567
Species: Human
Expression System: E. coli
c-Kit Protein, Human, Recombinant (aa 540-972, His & GST)
Cat.No: TMPY-04564
Species: Human
Expression System: Baculovirus Insect Cells
c-Kit Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06656
Species: Human
Expression System: HEK293 Cells
Major allergen I polypeptide chain 1 Protein, Feline, Recombinant (His & Myc)
Cat.No: TMPH-00355
Species: Feline
Expression System: E. coli
c-Kit Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01801
Species: Mouse
Expression System: HEK293 Cells
CD117 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00402
Species: Human
Expression System: HEK293 Cells
IL-7 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00038
Species: Mouse
Expression System: HEK293 Cells
FES Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04421
Species: Human
Expression System: Baculovirus Insect Cells
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