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Search Results for " ergoline "

Targets Recommended: Others

19

抑制剂 & 化合物

1

天然产物

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T9793	Methyl Ergoline Acid	Others	Others
	Methyl Ergoline Acid 是一种麦角碱衍生物，可用作趋化因子受体配体。
T31663	Lysergamide, N-cycloheptyl-, maleate Ergoline-8-beta-carboxamide, N-cycloheptyl-9,10-didehydro-6-methyl-, maleate	Others	Others
	Lysergamide, N-cycloheptyl-, maleate 可用于生命科学领域的相关研究。其产品编号为 T31663，CAS号为 103070-86-6。
T31664	Lysergamide, N-cyclopropyl-, maleate Ergoline-8-beta-carboxamide, N-cyclopropyl-9,10-didehydro-6-methyl-, maleate	Others	Others
	Ergoline-8-beta-carboxamide, N-cyclopropyl-9,10-didehydro-6-methyl-, maleate is a bioactive chemical.
T2226	Pergolide mesylate 甲磺酸培高利特,Pergolide mesylate salt,LY127809,Pergolide methanesulfonate	Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Pergolide mesylate salt(LY127809) 是一种有效的，具有口服活性的多巴胺 D1和 D2受体激动剂，是一种 Ergoline 衍生物，可用于帕金森氏病和高泌乳素血症的研究。
T1132	Nicergoline 尼麦角林,Nicergolinum,Nimergoline	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Nicergoline (Nicergolinum) 是一种有效的，选择性的、具有口服活性的α1A-肾上腺素能受体拮抗剂，是一种溴烟碱酸的麦角林衍生物。它具有血管舒张作用，可以改善阿尔茨海默症小鼠的认知功能。
T4008	Metergoline 甲麦角林,Methergoline,Liserdol	Dopamine Receptor; 5-HT Receptor; Sodium Channel	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Metergoline (Methergoline) 是多巴胺激动剂和血清素拮抗剂。它是 h5-HT7受体的高亲和力配体，Ki 为 16 nM。它还是可逆神经 Na+通道抑制剂，用于研究季节性情绪障碍、催乳激素调节。
T71707L	Romergoline 2HCl Romergoline 2HCl(107052-56-2 Free base),FCE 23884 2HCl	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Romergoline 2HCl 是一种 D1 激动剂和 D2 拮抗剂，可用于研究帕金森病。
T71707	Romergoline	Others	Others
	Romergoline 是一种新合成的麦角碱衍生物，具有独特的药理作用，在正常动物中表现出完全的多巴胺(DA)拮抗作用，而在“去神经”动物模型中表现出完全的DA 拮抗作用。
T68551	Cabergoline diphosphate	Others	Others
	Cabergoline diphosphate is a dopamine D2 receptor agonist used for prolactinoma treatment. Cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels.
T25247	Cianergoline Cianergolinum	Others	Others
	Cianergoline is a dopaminergic agonist.
T1132L	Nicergoline tartrate Adavin	Others	Others
	Nicergoline tartrate is a bioactive chemical.
T11011	Dexpramipexole dihydrochloride 普拉克索杂质D,KNS-760704 dihydrochloride,R-(+)-Pramipexole dihydrochloride,右旋普拉克索二盐酸盐,(R)-Pramipexole dihydrochloride	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Dexpramipexole dihydrochloride (KNS-760704 dihydrochloride) 是一种神经保护剂，是一种弱的非麦角类多巴胺受体激动剂。
T25671L	Lergotrile mesylate LY83636,LY-83636,LY 83636	Others	Others
	Lergotrile mesylate, an ergoline derivative, suppresses prolactin in vivo and in vitro.
T25657	LEK 8841 LEK-8841,LEK8841	Others	Others
	LEK 8841 is an ergoline derivative that is a potential antipsychotic.
T34432	RU 28306 RU-28306,RU28306	Others	Others
	RU 28306 is a racemic partial ergoline.
T24003	Disulergine CM 29717,CH 29717,CH 29-717	Others	Others
	Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.
TQ0175	Dexpramipexole 右旋普拉克索,R-(+)-Pramipexole,(R)-Pramipexole,KNS-760704	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Dexpramipexole (KNS-760704, R-(+)-Pramipexole) is a neuroprotective agent and weak non-ergoline dopamine agonist.
T21340	Pergolide	Others	Others
	Pergolide, an ergoline-based dopamine receptor agonist, is used for the treatment of Parkinson's disease, which is associated with low levels of the neurotransmitter dopamine in the brain.
T68440	Epicriptine	Others	Others
	Epicriptine or beta-dihydroergocryptine is a dopamine agonist of the ergoline class. It constitutes one third of the mixture known as dihydroergocryptine, the other two thirds consisting of alpha-dihydroergocryptine. The alpha differs from the beta form only in the position of a single methyl group, which is a consequence of the biosynthesis in which the proteinogenic amino acid isoleucine is replaced by leucine.

化合物

Methyl Ergoline Acid

Cat.No: T9793

Target: Others

Lysergamide, N-cycloheptyl-, maleate

Cat.No: T31663

Synonym: Ergoline-8-beta-carboxamide, N-cycloheptyl-9,10-didehydro-6-methyl-, maleate

Target: Others

Lysergamide, N-cyclopropyl-, maleate

Cat.No: T31664

Synonym: Ergoline-8-beta-carboxamide, N-cyclopropyl-9,10-didehydro-6-methyl-, maleate

Target: Others

Pergolide mesylate

Cat.No: T2226

Synonym: 甲磺酸培高利特,Pergolide mesylate salt,LY127809,Pergolide methanesulfonate

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor

Cat.No: T1132

Synonym: 尼麦角林,Nicergolinum,Nimergoline

Target: Adrenergic Receptor

Cat.No: T4008

Synonym: 甲麦角林,Methergoline,Liserdol

Target: Dopamine Receptor, 5-HT Receptor, Sodium Channel

Romergoline 2HCl

Cat.No: T71707L

Synonym: Romergoline 2HCl(107052-56-2 Free base),FCE 23884 2HCl

Target: Dopamine Receptor

Cat.No: T71707

Target: Others

Cabergoline diphosphate

Cat.No: T68551

Target: Others

Cat.No: T25247

Synonym: Cianergolinum

Target: Others

Nicergoline tartrate

Cat.No: T1132L

Synonym: Adavin

Target: Others

Dexpramipexole dihydrochloride

Cat.No: T11011

Synonym: 普拉克索杂质D,KNS-760704 dihydrochloride,R-(+)-Pramipexole dihydrochloride,右旋普拉克索二盐酸盐,(R)-Pramipexole dihydrochloride

Target: Dopamine Receptor

Lergotrile mesylate

Cat.No: T25671L

Synonym: LY83636,LY-83636,LY 83636

Target: Others

Cat.No: T25657

Synonym: LEK-8841,LEK8841

Target: Others

Cat.No: T34432

Synonym: RU-28306,RU28306

Target: Others

Cat.No: T24003

Synonym: CM 29717,CH 29717,CH 29-717

Target: Others

Cat.No: TQ0175

Synonym: 右旋普拉克索,R-(+)-Pramipexole,(R)-Pramipexole,KNS-760704

Target: Dopamine Receptor

Cat.No: T21340

Target: Others

Cat.No: T68440

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T14853	Cabergoline FCE-21336,卡麦角林	Dopamine Receptor; 5-HT Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Cabergoline (FCE-21336) 是一种麦角衍生的多巴胺 D2亚类受体激动剂，高亲和力作用于D2、D3和5-HT2B 受体，Ki 分别为 0.7、1.5 和 1.2。

天然产物

Cat.No: T14853

Synonym: FCE-21336,卡麦角林

Target: Dopamine Receptor, 5-HT Receptor, Autophagy

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0251	Nicergoline-13C-d3
	Nicergoline-13C-d3 是 Nicergoline 的 13C 和氘代化合物。Nicergoline 的 CAS 号为 27848-84-6。Nicergoline 是一种有效的，选择性的、具有口服活性的α1A-肾上腺素能受体拮抗剂，是一种溴烟碱酸的麦角林衍生物。它具有血管舒张作用，可以改善阿尔茨海默症小鼠的认知功能。

同位素标记化合物

Nicergoline-13C-d3

Cat.No: TMIJ-0251

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