DOTA tert-butylester is a phenyl derivative of cycloteramide; it can be directly nitrated; it is more convenient to add nitro after deprotection of lithium aluminum hydride.
FmocNH-PEG4-t-butylester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Hydroxy-PEG12-t-butylester is a PEG derivative containing a hydroxyl group and a t-butylester. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Under acidic conditions, the t-butyl protected carbox