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Cat. No. | Product Name | ||
---|---|---|---|
L9600 | 多肽分子库 | 791 compounds | |
791 种多肽类分子,可用于多肽药物开发及信号转导通路和作用机制研究; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP2491 |
Palmitoyl Dipeptide-5 Acetate
Palmitoyl Dipeptide-5 Acetate(794590-34-4 Free base) |
Others | Others |
Palmitoyl Dipeptide-5 Acetate 是一种多肽,是一种化妆品原料,可改善皮肤质量,防止皮肤衰老。 | |||
T7895 |
Syn-Ake acetate
类蛇毒三肽,Dipeptide diaminobutyroyl benzylamide |
AChR | Neuroscience |
Syn-Ake acetate (Dipeptide diaminobutyroyl benzylamide) 是一种毒蕈碱乙酰胆碱受体拮抗剂。 | |||
TP2397 |
Ornithine glutamate dipeptide
Orn-glu |
||
Ornithine glutamate dipeptide is a amino acid. | |||
T5286 |
Glycylglycine
Glycyl-glycine,Glycine dipeptide,Diglycocoll,Diglycine,Gly-gly,双甘肽,N-Glycylglycine |
Others; Endogenous Metabolite | Metabolism; Others |
Glycylglycine (Diglycine) 是一种简单的多肽,能够作为谷氨酰胺 (gamma-glutamyl) 的受体。 | |||
TP1390 |
CEP dipeptide 1
|
||
CEP dipeptide 1, a potent angiogenic compound, exhibits robust activity in promoting angiogenesis. This compound is specifically implicated in the pathogenesis of age-related macular degeneration (AMD). | |||
T16159 |
Muramyl dipeptide
MDP |
NOD | Immunology/Inflammation; NF-κB |
Muramyl dipeptide (MDP) 是合成的免疫反应肽,由 N-乙酰壁酸与 L-Ala-D-isoGln 的短氨基酸链相连。它通过MAPK 途径上调 Runx2 基因表达,直接促进成骨细胞分化,通过降低 RANKL/OPG 比值间接抑制破骨细胞分化。它是通过Runx2诱导骨形成的诱导因子,也是NLRP1激动剂。 | |||
TP2398 |
Palmitoyl dipeptide-7
PAL-KT,Palmitoyl-lysine-threonine |
||
Palmitoyl dipeptide-7 is a peptide. | |||
T29823 |
Alanyl ornithine
Dipeptide ao-a |
Others | Others |
Alanyl ornithine is a dipeptide. | |||
T33083 |
Lysyl threonine
L-Threonine, l-lysyl-,Dipeptide-7,Dipeptide KT |
Others | Others |
Lysyl threonine is a dipeptide composed of lysine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. | |||
T83202 |
Acetyl dipeptide-3 aminohexanoate
|
||
Acetyl dipeptide-3 aminohexanoate为生物活性肽,具抗衰老(anti-aging)功能,广泛应用于化妆品成分。 | |||
T81567 |
Palmitoyl dipeptide-5 diaminohydroxybutyrate
|
||
Palmitoyl dipeptide-5 diaminohydroxybutyrate,一种生物活性肽,具有抗衰老 (anti-aging) 功能,常作为化妆品成分使用。 | |||
T81568 |
Palmitoyl dipeptide-5 diaminobutyroyl hydroxythreonine
|
||
Palmitoyl dipeptide-7, 一种化妆品成分,以其生物活性肽特性作用于抗衰老。 | |||
T83203 |
Acetyl dipeptide-1 cetyl ester
Calmosensine |
||
Acetyl dipeptide-1 cetyl ester(Calmosensine)为一种具抗衰老(anti-aging)功能的生物活性肽,常作为化妆品成分。 | |||
T40840 |
H-Tyr-Ala-OH
H-Tyr-Ala-OH,Tyrosylalanine |
Others | Others |
H-Tyr-Ala-OH (Tyrosylalanine) 是一种L-酪氨酸和L-丙氨酸组成的二肽。 | |||
T0697 |
Aspartame
阿斯巴甜,SC-18862 |
Others; Taste receptor | Metabolism; Others |
Aspartame (SC-18862) 是一种二肽的甲酯,由苯丙氨酸 (50%),天门冬氨酸 (40%) 和甲醇 (10%) 组成。它可用作合成的非营养性甜味剂。 | |||
T7511 |
Cyclo(his-pro)
|
NF-κB; Endogenous Metabolite | Metabolism; NF-κB |
Cyclo(his-pro) 是一种口服具有活力的,结构上与促甲状腺激素释放激素相关的环状二肽。它能够抑制NF-κB 核积累,也能够穿越脑血屏障并影响多种炎症和应激反应。 | |||
TP1088 |
N-Acetylcarnosine
N-Acetyl-L-carnosine,N-乙酰肌肽 |
Others | Others |
N-Acetylcarnosine (N-Acetyl-L-carnosine) 是一种含有组氨酸的天然二肽,是药理学上主要的 L-carnosine 的来源。它是一种眼科药物,对人类白内障具有潜在的应用价值。 | |||
T5593 |
L-Alanyl-L-glutamine
L-丙氨酰-L-谷氨酰胺,L-丙氨酸-L-谷氨酰胺,Ala-Gln |
Others; Endogenous Metabolite | Metabolism; Others |
L-Alanyl-L-glutamine (Ala-Gln) 是一种由丙氨酸和谷氨酰胺组成的二肽,对抗氧化系统有益,能够减轻炎症,并能够在分解代谢情况下调节热休克蛋白 (HSP) 的反应。 | |||
T19335 |
Danegaptide Hydrochloride
GAP-134 (Hydrochloride),ZP 1609 Hydrochloride,(4R)-甘氨酰基-4-(苯甲酰基氨基)-L-脯氨酸盐酸盐 |
Gap Junction Protein | Cytoskeletal Signaling |
Danegaptide Hydrochloride (GAP-134 (Hydrochloride)) 是一种具有口服活性的间隙连接蛋白选择性修饰剂,具有抗心律不齐的作用。 | |||
T19350 |
H-Val-Ala-OH
缬氨酰-丙氨酸,Valyl-alanine |
Endogenous Metabolite | Metabolism |
H-Val-Ala-OH (Valyl-alanine) 是由 L-缬氨酸和 L-丙氨酸残基形成的二肽,具有代谢作用。 | |||
T38485L |
Fmoc-Gly-Ser(psi(Me,Me)pro)-OH acetate
|
Others | Others |
Fmoc-Gly-Ser(psi(Me,Me)pro)-OH acetate 是一种二肽。 | |||
T25146 |
Bestim
|
Others | Others |
Bestim 是一种合成的免疫调节二肽。 | |||
T20163 |
Acetyltrialanine
|
||
Acetyltrialanine 是一种二肽化合物,在 Tb+3-胰腺弹性蛋白酶复合物上的两个位点结合,可做为氮源使用。 | |||
T20566L |
Valylvaline acetate
|
Others | Others |
Valylvaline acetate 是一种二肽和 PEPT1 激动剂,EC50 为 0.07mM。 | |||
T8054 |
L-Leucyl-L-alanine
Leucyl-alanine,L-Leucyl-L-alanine Hydrate,L-亮氨酸-L-丙氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
L-Leucyl-L-alanine 是由 L-亮氨酸和 L-丙氨酸组成的简单二肽。 | |||
T8104 |
Glycyl-L-valine
|
Others; Endogenous Metabolite | Metabolism; Others |
Glycyl-L-valine 是含有甘氨酸和缬氨酸的二肽。 | |||
TP1264 |
Prolylleucine
((Benzyloxy)carbonyl)-L-prolyl-D-leucine |
Others | Others |
Prolylleucine (((Benzyloxy)carbonyl)-L-prolyl-D-leucine) 是一种二肽,含有支链氨基酸,可以影响动物的昼夜节律和行为。 | |||
T5589 |
H-Gly-Pro-OH
Glycyl proline,甘油-L-脯氨酸,Glycyl-L-proline |
Endogenous Metabolite | Metabolism |
H-Gly-Pro-OH (Glycyl proline) 是胶原蛋白代谢的最终产物,能够被脯氨肽酶进一步裂解。 | |||
T80665 |
Leu-Val
L-leucyl-L-valine |
Parasite; Antifungal | Microbiology/Virology |
Leu-Val (L-leucyl-L-valine) 是一种新型有效的二肽,具有抗菌和抗疟活性。 | |||
T8915 |
Glycylsarcosine
GLYCYL-SARCOSINE,甘氨酰肌氨酸 |
Others | Others |
Glycylsarcosine (GLYCYL-SARCOSINE) 是由甘氨酸的羧基与肌氨酸的氨基缩合而成的二肽 | |||
T8037 |
H-Phe-Phe-OH
|
Endogenous Metabolite | Metabolism |
H-Phe-Phe-OH 是一种两分子苯丙氨酸组成的多肽,苯丙氨酸是必需氨基酸,酪氨酸的前体。 | |||
T7108 |
Omberacetam
SGS-111,Noopept,GVS-111 |
Others; iGluR | Membrane transporter/Ion channel; Neuroscience; Others |
Omberacetam (Noopept) 是一种可作为膳食补充剂的合成二肽,有促智和提高认知作用。 | |||
TP1156 |
H-Gly-Gly-Pro-OH
Glycyl-glycyl-L-proline |
Others | Others |
H-Gly-Gly-Pro-OH (Glycyl-glycyl-L-proline) 是由甘氨酸和脯氨酸组成的二肽,是胶原代谢的终产物,被脯氨酸酶进一步裂解。 | |||
T15079 |
DBPR108
|
Proteasome; DPP-4 | Proteases/Proteasome; Ubiquitination |
DBPR108是新型、具有口服活性、选择性的DPP4抑制剂,IC50=为15nM,对DPP8和DPP9基本无抑制。 | |||
T1532 |
Pidotimod
|
Others; Antibacterial | Microbiology/Virology; Others |
Pidotimod 是一种具有免疫调节特性的合成二肽。它增加巨噬细胞活性和体液免疫功能。它可研究慢性支气管炎、慢性阻塞性肺疾病 、支气管扩张、慢性特发性荨麻疹等。 | |||
T33639 |
Neotame
NC 00723,HSDB 7965,NC-00723,NC00723,纽甜 |
Others | Others |
Neotame (HSDB 7965) 是阿斯巴甜的衍生物,是低热量、高效的人造甜味剂,非营养性甜味剂和增味剂,其甜度是糖的 7000-13,000 倍,可用于多种食品。 | |||
T36879L |
H-Leu-Leu-OMe . HBr
H-Leu-Leu-OMe . HBr (16689-14-8 Free base) |
Others | Others |
H-Leu-Leu-OMe . HBr 是由人单核细胞或多形核白细胞产生的L-亮氨酸甲酯的二肽缩合产物。 H-Leu-Leu-OMe . HBr 诱导内溶酶体途径应激并选择性地消除具有细胞毒性潜力的淋巴细胞。 | |||
T32098L |
Homocarnosine acetate
|
GABA Receptor; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism; Neuroscience |
Homocarnosine acetate 是大脑特有的二肽,由 γ-氨基丁酸 (GABA) 和组氨酸组成。它具有抗氧化和抗炎作用、预防 DNA 损伤和抑制晚期糖基化终产物形成 | |||
T80640 |
EBOV-IN-1
|
Influenza Virus | Microbiology/Virology |
EBOV-IN-1 是一种针对埃博拉病毒(EBOV)的金刚烷二肽哌嗪抑制剂。它通过与Niemann-Pick C1 (NPC1)相互作用,阻断该蛋白与启动病毒穿透宿主细胞的EBOV糖蛋白(GP)的结合,进而抑制EBOV的感染。EBOV-IN-1对假型EBOV感染具有IC50为13 nM的抑制效力。 | |||
T50068 |
(2S,5S)-3,6-Dioxo-2,5-piperazinediacetamide
|
Others | Others |
2-[(2S,5S)-5-(carbamoylmethyl)-3,6-dioxopiperazin-2-yl]acetamide 是一种用作分子结构单元的化合物,为环状二肽。它可以诱导细胞凋亡、抑制细胞增殖和调节免疫反应,具有广泛的生物活性,包括抗肿瘤、抗真菌、抗细菌、抗病毒和免疫条件活性等。 | |||
TP1266 |
γ-Glu-Phe TFA(7432-24-8 free base)
γ-Glu-Phe TFA(7432-24-8,FREE) |
Endogenous Metabolite | Metabolism |
γ-Glu-Phe TFA(7432-24-8 free base) 是由γ-谷氨酸和苯丙氨酸组成的二肽,是较大蛋白质的蛋白水解分解产物。它可能是由谷胱甘肽与相应氨基酸之间的转肽作用形成的,由γ-谷氨酰转肽酶催化。 | |||
T22243 |
Anserine
L-鹅肌肽,L-Anserine |
Endogenous Metabolite | Metabolism |
Anserine (L-Anserine) 是 Carnosine 的甲基化形式,是口服具有活性的天然二肽,存在于脊椎动物的骨骼肌。它不会被血清肌肽酶裂解,能够作为生化缓冲液,螯合剂,抗糖化剂和抗氧化剂。它能够改善阿尔茨海默氏病模型小鼠的记忆功能。 | |||
T11449L |
Golotimod
Gamma-D-glutamyl-L-tryptophan,SCV 07 |
Antibiotic | Microbiology/Virology |
Golotimod (SCV 07) 是一种具有抗菌活性的二肽,具有免疫调节活性,能显著提高抗结核治疗的疗效,诱导胸腺和脾脏细胞增殖,调节巨噬细胞功能,抑制 STAT3 信号传导。Golotimod 可用于研究复发性生殖器单纯疱疹病毒 2 (HSV-2)感染和口腔黏膜炎。 | |||
T20554 |
N-Benzoyltyrosine
N-Benzoyl-L-tyrosine |
Others | Others |
N-benzoyl tyrosine is a dipeptide. | |||
T34768 |
Tabtoxin
|
Others | Others |
Tabtoxin is a dipeptide containing tabtoxinine-beta-lactam with threonine. | |||
T40175 |
Fmoc-Ala-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Ala-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T32214 |
Isoleucylvaline
Ile-val |
Others | Others |
Isoleucylvaline is a dipeptide. | |||
T20556 |
Tyrosyltyrosine
Tyr-tyr,Peptide tyrosine-tyrosine,Tyrosyl tyrosine |
Others | Others |
Tyrosyltyrosine is a dipeptide. | |||
T32788 |
LISA-4
H-Glu[Ser(CO-MU)]-OH,LISA 4 |
Others | Others |
LISA-4 is the first fluorescent dipeptide probe for γ-glutamyl cyclotransferase. | |||
T41118 |
Fmoc-Lys(Boc)-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Lys(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN6444 |
Cyclo(Tyr-Leu)
|
Antifungal | Microbiology/Virology |
Cyclo(Tyr-Leu) 是一种来自马齿苋 Portulaca oleracea Linn 的环状二肽,具有细胞毒性、抗真菌和抗凝血活性。 | |||
T40490 |
Phenylalanylalanine
H-Phe-Ala-OH,苯并氨酰丙氨酸 |
Others | Others |
Phenylalanylalanine(H-Phe-Ala-OH)是由苯丙氨酸和丙氨酸融合形成的二肽。它在蛋白质的不完全消化或分解过程中形成[1]。 | |||
T39359 |
γ-Glu-Gly
gamma-Glutamylglycine |
Amino Acids and Derivatives | Metabolism |
γ-Glu-Gly(gamma-Glutamylglycine),一种γ-谷氨酰基二肽,是具有与GABA(γ-氨基丁酸)相似结构的人体脂质代谢产物,可作为兴奋性氨基酸的拮抗剂。 | |||
T4704 |
L-Anserine nitrate
L-鹅肌肽硝酸盐,L-Anserine nitrate salt |
Others; Endogenous Metabolite | Metabolism; Others |
L-Anserine nitrate (L-Anserine nitrate salt) 是一种存在于大多数动物组织中的二肽。在模型系统中,它是一种有效的抗氧化剂和羟基自由基清除剂。该化合物抑制醛糖和酮糖还原糖诱导的非酶蛋白糖基化。 | |||
T1257 |
Bestatin
Ubenimex,乌苯美司 |
Others; Aminopeptidase; Antibacterial; Antibiotic; LTR | Immunology/Inflammation; Metabolism; Microbiology/Virology; Others |
Bestatin (Ubenimex) 是 CD13 (Aminopeptidase N)/APN 和 leukotriene A4 hydrolase 抑制剂,可用于癌症研究。 | |||
T37753 |
Aureusimine B
|
Cysteine Protease; Antibacterial | Microbiology/Virology; Proteases/Proteasome |
Aureusimine B 是一种钙蛋白酶抑制剂,由金黄色葡萄球菌生物膜产生,可能是金黄色葡萄球菌生物膜感染的潜在生物标志物。 | |||
TN6447 |
Cyclo(Leu-Val)
|
||
Cyclo(Leu-Val) is a cyclic dipeptide from the fermentation broth of F8712 strain. | |||
T20555 |
Glycyltyrosine
NSC 118362,Gly Tyr,NSC-118362,Gly-Tyr,NSC118362,N-Glycyl-L-tyrosine |
Others | Others |
Glycyltyrosine, a dipeptide composed of tyrosine and glycine, is an incomplete breakdown product of protein catabolism or protein digestion. | |||
T35401 |
γ-Glu-Gly TFA
|
Others | Others |
γ-Glu-Gly TFA, a γ-glutamyl dipeptide, is a human lipid metabolite with a structure resembling GABA (γ-aminobutyric acid). It serves as an excitatory amino acid antagonist [1][2][3]. | |||
T61171 |
Cyclo(his-pro) TFA
|
Others | Others |
Cyclo(his-pro) TFA, an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone, has shown inhibitory effects on NF-κB nuclear accumulation. Additionally, it possesses the ability to cross the blood-brain barrier and impact various inflammatory and stress responses [1, 2]. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00679 |
Peptide deformylase Protein, E. coli O157:H7, Recombinant (His)
Polypeptide deformylase,Peptide deformylase,def |
E. coli | P. pastoris (Yeast) |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | |||
TMPH-00702 |
Peptide deformylase Protein, E. coli, Recombinant (His & SUMO)
Polypeptide deformylase,def,Peptide deformylase |
E. coli | E. coli |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.2 kDa and the accession number is P0A6K3. | |||
TMPH-03567 |
Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO)
Peptide deformylase,def,Polypeptide deformylase |
Staphylococcus aureus | E. coli |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.6 kDa and the accession number is P68826. | |||
TMPH-00678 |
Peptide deformylase Protein, E. coli O157:H7, Recombinant (His & SUMO)
Peptide deformylase,def,Polypeptide deformylase |
E. coli | E. coli |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, E. coli O157:H7, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.2 kDa and the accession number is P0A6K5. | |||
TMPH-03566 |
Peptide deformylase Protein, S. aureus, Recombinant (His)
Polypeptide deformylase,def,Peptide deformylase |
Staphylococcus aureus | P. pastoris (Yeast) |
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 22.6 kDa and the accession number is P68826. | |||
TMPJ-01350 |
XPNPEP3 Protein, Human, Recombinant (His)
XPNPEP3,X-Pro Aminopeptidase 3,Aminopeptidase P3,APP3,Probab... |
Human | E. coli |
Probable Xaa-Pro Aminopeptidase 3 (XPNPEP3) is a member of the peptidase M24B family. XPNPEP3 has two isoforms and both are widely expressed. XPNPEP3 is localized in the Mitochondrion. XPNPEP3 catalyzes the release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. Defects in XPNPEP3 are the cause of nephronophthisis-like nephropathy type 1 which is a disorder with features of nephronophthisis, a cystic kidney disease leading to end-s... | |||
TMPJ-01358 |
DPP3 Protein, Human, Recombinant (His)
Dipeptidyl arylamidase III,Dipeptidyl aminopeptidase III,Dip... |
Human | E. coli |
Dipeptidyl peptidase 3(DPP3), is a member of the S9B family in clan SC of the serine proteases. DPP3 has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH). It releases an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity and also acts on dipeptidyl 2-naphthylamides.Increased activity of this protein has a relat... | |||
TMPY-01306 |
DNMT2 Protein, Human, Recombinant (GST)
PUMET,RNMT1,tRNA aspartic acid methyltransferase 1,MHSAIIP,D... |
Human | Baculovirus Insect Cells |
DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of enzymes. DNMT2 enzymes have been widely conserved during evolution and contain all of the signature motifs of DNA (cytosine-5)-methyltransferases. It contains all 10 sequence motifs that are conserved among m(5)C MTases, including the consensus S:-adenosyl-L-methionine-binding motifs and the active site ProCys dipeptide, and its structure... | |||
TMPY-01761 |
Carbonic Anhydrase 3 Protein, Human, Recombinant (His)
carbonic anhydrase III,CAIII,Car3 |
Human | E. coli |
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Carbonic anhydrases (CAs) form a family of enzymes that catalyze the rapid conversion of carbon dioxide and water to bicarbonate an... | |||
TMPH-02521 |
PYCARD Protein, Mouse, Recombinant (His & Myc)
Pycard,PYD and CARD domain-containing protein,Apoptosis-asso... |
Mouse | E. coli |
Functions as key mediator in apoptosis and inflammation. Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner. Involved in activation of the mitochondrial apoptotic pathway, promotes caspase-8-dependent proteolytic maturation of BID independently of FADD in certain cell types and also mediates mitochondrial translocation of BAX and activates BAX-dependent apoptosis coupled to activation of caspase-9, -2 and -3. Involved ... |