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Search Results for " community-acquired "

Targets Recommended: ribosome Antibacterial Antibiotic

16

抑制剂 & 化合物

1

天然产物

1

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T5189	Omadacycline PTK 0796,Amadacycline	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Omadacycline (Amadacycline) 是一种具有口服活性的氨基甲基环素抗菌剂，是四环素类抗生素。它与 30S 核糖体亚基结合，抑制细菌蛋白质合成。它可用于研究急性细菌性皮肤和皮肤结构感染，感染性肺炎和尿路感染。
T0331	Moxifloxacin hydrochloride 盐酸莫西沙星,莫西沙星盐酸盐,BAY-128039,Moxifloxacin HCl,BAY12-8039 HCl	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Moxifloxacin hydrochloride (BAY12-8039 HCl) 是一种口服有效的 8-甲氧基喹诺酮类抗菌药物，可研究感染性肺炎，急性细菌性鼻窦炎和慢性支气管炎的急性细菌性加重。
T10987	Decarboxy Moxifloxacin	Others	Others
	Decarboxy Moxifloxacin 是一种莫西沙星的脱羧化合物。Moxifloxacin 是一种能够口服的 8-甲氧基喹诺酮类抗菌药物，可用于急性细菌性鼻窦炎，慢性支气管炎的急性细菌性加重和感染性肺炎。
T74821	Nemonoxacin TG-873870	Antibacterial	Microbiology/Virology
	Nemonoxacin (TG-873870) 是一种可口服的非氟化喹诺酮类抗生素，具有广谱的抗菌活性，抑制葡萄球菌、链球菌和肠球菌、淋病奈瑟菌和流感嗜血杆菌均。Nemonoxacin 可用于研究细菌感染和社区获得性肺炎。
T11836	Lefamulin acetate BC-3781 acetate,醋酸来法莫林	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Lefamulin acetate (BC-3781 acetate) 是具有口服活性的抗生素。它是用于人体细菌感染的全身研究的半合成截短侧耳素。它与 50S 细菌核糖体的肽基转移酶peptidyl transferase 中心结合抑制蛋白质合成，并阻止了转移RNA 与肽转移的结合。
T38586	Grepafloxacin dl-Grepafloxacin,OPC-17116	Others	Others
	Grepafloxacin (OPC-17116) is a fluoroquinolone antibiotic that is administered orally. It possesses strong efficacy against community-acquired respiratory pathogens, notably Streptococcus pneumonia. Grepafloxacin exhibits excellent tissue penetration and demonstrates a promising pharmacodynamic profile.
T28997	TP-271 TP271	Others	Others
	TP-271, a tetracyclines antibiotic, is used potentially for the treatment of community-acquired bacterial pneumonia (CABP).
T75274	Cefetamet	Others	Others
	Cefetamet 是一种头孢类抗生素。Cefetamet 具有研究上、下社区获得性呼吸道感染的潜力。
T23622	Acorafloxacin HCl JNJ-32729463,JNJ-Q2 hydrochloride,Acorafloxacin hydrochloride,JNJ 32729463,JNJ-Q2 HCl	Others	Others
	Acorafloxacin is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and skin structure infections and community-acquired pneumonia.
T10420	Avarofloxacin JNJ-Q2	Others	Others
	Avarofloxacin (JNJ-Q2) is a broad-spectrum fluoroquinolone antibacterial drug being developed for the treatment of acute bacterial skin and community-acquired pneumonia and skin structure infections.
T70642	Lanopepden camsylate	Others	Others
	Lanopepden, also known as GSK-1322322 or GSK-322, is a potent and selective peptide deformylase inhibitor with good in vitro activity against bacteria associated with community-acquired pneumonia and skin infections. GSK1322322 had bactericidal activity against S. pneumoniae, H. influenzae, S. pyogenes, and S. aureus, demonstrating a ≥ 3-log(10) decrease in the number of CFU/ml at 4× MIC within 24 h in 29 of the 33 strains tested. GSK1322322 represents a valuable alternative therapy for the trea...
T71266	Omadacycline HCl	Others	Others
	Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant Staphylococcus aureus (MRSA), β-hemolytic streptococci, penicillin-resistant Streptococcus pneumoniae, Haemophilus influenzae, and Legionella. Omadacycline is active against strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection). The pri...
T4543	Telithromycin HMR3647,泰利霉素,Ketek,RU66647	Antibacterial; Antibiotic	Microbiology/Virology
	Telithromycin (HMR3647) 是一种社区获得性肺炎抗生素。
T74144	Zifanocycline	Others	Others
	Zifanocycline (KBP-7072) 为半合成第三代氨甲基环素类抗生素，通过抑制细菌核糖体功能而发挥作用。它对革兰氏阳性菌和革兰氏阴性菌[包括多重耐药病原体]显示出广泛的体外抗菌活性。适用于口服和注射形式，Zifanocycline 主要用于研究治疗急性细菌性皮肤及其结构感染、社区获得性细菌性肺炎以及复杂腹腔感染。
T74591	Ceftaroline fosamil (hydrate)(acetate)	Others	Others
	Ceftaroline fosamil hydrate acetate 是一种高效的头孢菌素类抗生素(antibiotic)，对多种病原体有广谱活性，特别是针对革兰氏阳性病原体，如耐甲氧西林金黄色葡萄球菌(MRSA)和耐多药肺炎链球菌，以及常见的革兰氏阴性微生物。此外，Ceftaroline fosamil hydrate acetate 在治疗复杂皮肤及皮肤结构感染(cSSSIs)和社区获得性肺炎(CABP)方面表现出显著的抗感染活性。
T80731	Zifanocycline TFA KBP-7072 TFA	Others	Others
	Zifanocycline TFA (KBP-7072) 是一种半合成的氨基糖苷类抗生素，具有口服活性并能抑制细菌核糖体功能。它对广泛的革兰氏阳性菌和阴性菌示出了体外抗菌活性，包括多种耐药病原体。Zifanocycline TFA 适用于急性细菌性皮肤及皮肤结构感染、社区获得性细菌性肺炎和复杂的腹腔感染的研究。

化合物

Cat.No: T5189

Synonym: PTK 0796,Amadacycline

Target: ribosome, Antibacterial, Antibiotic

Moxifloxacin hydrochloride

Cat.No: T0331

Synonym: 盐酸莫西沙星,莫西沙星盐酸盐,BAY-128039,Moxifloxacin HCl,BAY12-8039 HCl

Target: Topoisomerase, Antibacterial, Antibiotic

Decarboxy Moxifloxacin

Cat.No: T10987

Target: Others

Cat.No: T74821

Synonym: TG-873870

Target: Antibacterial

Lefamulin acetate

Cat.No: T11836

Synonym: BC-3781 acetate,醋酸来法莫林

Target: ribosome, Antibacterial, Antibiotic

Cat.No: T38586

Synonym: dl-Grepafloxacin,OPC-17116

Target: Others

Cat.No: T28997

Synonym: TP271

Target: Others

Cat.No: T75274

Target: Others

Acorafloxacin HCl

Cat.No: T23622

Synonym: JNJ-32729463,JNJ-Q2 hydrochloride,Acorafloxacin hydrochloride,JNJ 32729463,JNJ-Q2 HCl

Target: Others

Cat.No: T10420

Synonym: JNJ-Q2

Target: Others

Lanopepden camsylate

Cat.No: T70642

Target: Others

Omadacycline HCl

Cat.No: T71266

Target: Others

Cat.No: T4543

Synonym: HMR3647,泰利霉素,Ketek,RU66647

Target: Antibacterial, Antibiotic

Cat.No: T74144

Target: Others

Ceftaroline fosamil (hydrate)(acetate)

Cat.No: T74591

Target: Others

Zifanocycline TFA

Cat.No: T80731

Synonym: KBP-7072 TFA

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5041	Faropenem sodium 法罗培南,法罗培南钠	Antibacterial; Antibiotic	Microbiology/Virology
	Faropenem sodium 是一种口服生物可利用的青霉烯类抗生素，能有效杀灭结核分枝杆菌，治疗结核病和社区获得性肺炎。

天然产物

Faropenem sodium

Cat.No: T5041

Synonym: 法罗培南,法罗培南钠

Target: Antibacterial, Antibiotic

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03026	CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc) ADP-ribosylating toxin CARDS,CARDX TX,ADP-ribosyltransferase...	Mycoplasma pneumoniae	E. coli
	Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells.

重组蛋白

CARDS Protein, Mycoplasma pneumoniae, Recombinant (His & Myc)

Cat.No: TMPH-03026

Species: Mycoplasma pneumoniae

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0179	Faropenem-d7 Sodium Salt
	Faropenem-d7 Sodium Salt 是 Faropenem Sodium Salt 的氘代化合物。Faropenem Sodium Salt 的 CAS 号为 122547-49-3。Faropenem sodium 是一种口服生物可利用的青霉烯类抗生素，能有效杀灭结核分枝杆菌，治疗结核病和社区获得性肺炎。

同位素标记化合物

Faropenem-d7 Sodium Salt

Cat.No: TMIJ-0179

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