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Search Results for " cardiovascular hormone "
Targets Recommended: Others

7

抑制剂 & 化合物

1

天然产物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
TP1197 Sincalide

SQ19844,辛卡利特,CCK-8,Cholecystokinin octapeptide

Others Others
Sincalide (CCK-8) 是一种速效的胆囊收缩素的氨基酸多肽激素类似物,可在胆囊造影术中静脉使用。它的肝胆生理作用是增加胆汁的分泌,使胆囊收缩并使 Oddi 的括约肌松弛,从而使胆汁排入十二指肠。它是一种通过注射促进胆囊收缩并帮助诊断胆囊和胰腺疾病的药物。
TP1209 BNP (1-32), rat TFA (133448-20-1 free base)

Brain Natriuretic Peptide (BNP) (1-32), rat TFA,BNP (1-32), rat TFA

Acts as a cardiac hormone with a variety of biological actions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. Helps restore the body\'s sa
TP1342 GnRH-I

GnRH-I is a small 10 amino acid long peptide (decapeptide) from the hypothalamus,It is also known as luteinizing hormone releasing hormone (LHRH), is a key molecule in the regulation of reproduction in vertebrates. GnRH, a decapeptide, is produced by neur
T75970 Melanin Concentrating Hormone, salmon TFA

Melanin Concentrating Hormone, salmon TFA (MCH (salmon) TFA) 是在硬骨鱼的垂体中发现的 19 个氨基酸组成的神经肽,它调节食物摄入,能量平衡,睡眠状态和心血管系统。Melanin Concentrating Hormone, salmon TFA (MCH (salmon) TFA) 是 SLC-1/GPR24和 MCHR2的配体。
T76500 ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat)

ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) 是ACTH的3-24片段,适用于癌症、免疫疾病、心血管疾病等多种疾病的研究。
T75708 Argipressin diacetate

Argipressin (diacetate) (AVP (diacetate),又称antidiuretic hormone (ADH)) 是一种由垂体后叶分泌的含9个氨基酸的神经肽。通过作用于三种G蛋白偶联受体(GPCRs),Avpr1a (V1a)、Avpr1b (V1b) 及Avpr2 (V2),它调控体液平衡、渗透压及心血管系统的生理功能,并可能对中枢代谢过程产生重要影响。
T83905 Brain Natriuretic Peptide-32 (rat) acetate

BNP (14-45),B-type Natriuretic Peptide-32,Brain Natriuretic Polypeptide-32,BNP-32

BNP-32(Brain natriuretic peptide-32)是心血管激素前体proBNP的肽段,能够结合大鼠血管平滑肌上的利钠肽受体(IC50 = 7.3 nM),并在同样的细胞中促进cGMP积累(EC50 = 170 nM)。BNP-32还能使经去甲肾上腺素预收缩的孤立大鼠主动脉条带松弛(EC50 = 6.7 nM),当以3 µg/kg的剂量给药时,能增加大鼠的尿量和尿液电解质排泄,并诱导低血压。

化合物

Sincalide
Cat.No: TP1197
Synonym: SQ19844,辛卡利特,CCK-8,Cholecystokinin octapeptide
Target: Others
BNP (1-32), rat TFA (133448-20-1 free base)
Cat.No: TP1209
Synonym: Brain Natriuretic Peptide (BNP) (1-32), rat TFA,BNP (1-32), rat TFA
Target:
GnRH-I
Cat.No: TP1342
Synonym:
Target:
Melanin Concentrating Hormone, salmon TFA
Cat.No: T75970
Synonym:
Target:
ACTH (3-24) (human, bovine, mouse, ovine, porcine, rabbit, rat)
Cat.No: T76500
Synonym:
Target:
Argipressin diacetate
Cat.No: T75708
Synonym:
Target:
Brain Natriuretic Peptide-32 (rat) acetate
Cat.No: T83905
Synonym: BNP (14-45),B-type Natriuretic Peptide-32,Brain Natriuretic Polypeptide-32,BNP-32
Target:
Cat. No. Product Name Target Signaling Pathways
T3398 Icaritin

Anhydroicaritin,去水淫羊藿黄素,Cycloicaritin

Apoptosis; JAK; STAT; Autophagy Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
Icaritin (Anhydroicaritin) 是Epimedium Genusis 的异戊二烯类黄酮衍生物,有效抑制 K562 细胞和原代 CML 细胞的增殖。它可以调节MAPK/ERK/JNK 和JAK2/STAT3/AKT 信号传导,并具有增强成骨的作用。

天然产物

Icaritin
Cat.No: T3398
Synonym: Anhydroicaritin,去水淫羊藿黄素,Cycloicaritin
Target: Apoptosis, JAK, STAT, Autophagy
Cat. No. Product Name Species Expression System
TMPY-00319 GIP Protein, Human, Recombinant (hFc)

gastric inhibitory polypeptide,GIP

Human HEK293 Cells
Glucose-dependent insulinotropic polypeptide (GIP) is an incretin that plays an important role in fat accumulation. GIP is involved in fat accumulation and insulin resistance with aging. Glucose-dependent insulinotropic polypeptide (GIP) is an intestinal hormone with a broad range of physiological actions. Elevated concentrations of the incretin hormone GIP are found in patients with atherosclerotic cardiovascular disease, while GIP treatment attenuates atherosclerotic plaque inflammation in mi...

重组蛋白

GIP Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00319
Species: Human
Expression System: HEK293 Cells
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