搜索结果

Search Results for " cardiac diseases "

Targets Recommended: Others

抑制剂 & 化合物

天然产物

化合物库

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L7200	钙通道分子库	140 compounds
	140 种钙通道相关化合物的独特集合，可用于高通量筛选和高内涵筛选；
L7110	抗高血压化合物库	678 compounds
	678 种高血压相关的小分子，用于高通量和高内涵筛选；

化合物库

Cat. No.	Product Name	Target	Signaling Pathways
T22341	GSK-114	Others	Others
	GSK 114 是口服有活性的、高选择性的TNNI3K 抑制剂 (IC50= 25 nM)。其中TNNI3K (又称 CARK) 是酪氨酸样激酶家族的成员，选择性在心脏组织中表达。它对 TNNI3K 的选择性是 B-Raf 激酶的 40 倍 (IC50= 1 µM)。
T9245	TRPM4-IN-1 CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid	TRP/TRPV Channel	Membrane transporter/Ion channel
	TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) 是一种有效的阳离子通道TRPM4选择性抑制剂，IC50为 1.5 μM。TRPM4-IN-1 在心脏病和前列腺癌中具有研究价值。
T67748	ROCK-IN-5	ROCK; ERK	Cell Cycle/Checkpoint; Cytoskeletal Signaling; MAPK; Stem Cells
	ROCK-IN-5（化合物I-B-37）是一种有效的蛋白激酶抑制剂，包括ROCK、ERK、GSK 和AGC。ROCK-IN-5在心脏病、增殖性疾病和神经退行性疾病研究方面具有潜力。
T8366	Mitochonic acid 5 MA-5	Mitochondrial Metabolism	Metabolism
	Mitochonic acid 5 (MA-5) 能够调节线粒体 ATP 合成，可与线粒体结合，并改善肾小管和心肌细胞损伤。
T39442	AM-8123	Apelin receptor	GPCR/G Protein
	AM-8123 是一种可口服的非肽 APJ 激动剂。AM-8123 可减少胶原蛋白负荷并改善心脏功能。AM-8123 可改善大鼠心肌梗死，可用于研究心力衰竭等心血管疾病。
T65994	(6S)-N-Benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide	Others	Others
	Wnt signaling is required for direct multiple biological processes and also plays key roles in the pathogenesis of various diseases. Cyclic AMP response element-binding protein (CREB) is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation...

化合物

Synonym: CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid

Target: TRP/TRPV Channel

ROCK-IN-5

Cat.No: T67748

Synonym:

Target: ROCK, ERK

Mitochonic acid 5

Cat.No: T8366

Synonym: MA-5

Target: Mitochondrial Metabolism

AM-8123

Cat.No: T39442

Synonym:

Target: Apelin receptor

(6S)-N-Benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide

Cat.No: T65994

Synonym:

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T3212	Digoxigenin 地谷新配基,异羟基洋地黄毒苷元	Others	Others
	Digoxigenin, a therapeutic drug belonging to the group of cardiac glycosides, is widely used in the management of congestive heart failure and other cardiac diseases

天然产物

Digoxigenin

Cat.No: T3212

Synonym: 地谷新配基,异羟基洋地黄毒苷元

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01286	MMP-8 Protein, Cynomolgus, Recombinant (His) Collagenase 2,HNC,CLG1,MMP8,PMNL-CL	Cynomolgus	HEK293 Cells
	Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance of surrogate markers of extracellular matrix (ECM) remodeling. MMP-8 was identified only in myocardiocytes, while MMP-9 and TIMP-2 were present in both myocardiocytes and stroma, but with different intensity. The increasing intensity of MMP-8 and TIMP-2 immunoreactions was signifi...

重组蛋白

MMP-8 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01286

Species: Cynomolgus

Expression System: HEK293 Cells

* 搜索：		* 机关/企业：
* 邮箱：		* 电话：
备注：
验证码：

搜索结果

抑制剂 & 化合物

天然产物

化合物库

重组蛋白

提交您的定制咨询

化合物库

化合物

天然产物

重组蛋白