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Search Results for " beta-estradiol "

Targets Recommended: Estrogen Receptor/ERR

7

抑制剂 & 化合物

3

天然产物

4

重组蛋白

2

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T9604	beta-Estradiol 17-hemisuccinate	Estrogen Receptor/ERR	Endocrinology/Hormones
	beta-Estradiol 17-hemisuccinate 选择性染色富含雌激素受体 (ER) 的细胞。
T2231	Estradiol dipropionate 17-Beta-Estradiol-3,17-Dipropionate,3,17-二丙酸-17-BETA-雌二酯,二丙酸雌二醇	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Progesterone Receptor	Endocrinology/Hormones; Others
	Estradiol dipropionate (17-Beta-Estradiol-3,17-Dipropionate) 是雌激素-孕激素的组合物，可用作雌激素 (estrogen) 孕激素 (progesterone) 激动剂。
T72390	Estradiol hemihydrate 17β-Oestradiol hemihydrate,β-Estradiol hemihydrate ; 17β-Estradiol hemihydrate ; 17β-Oestradiol hemihydrate,17β-Estradiol hemihydrate,β-Estradiol hemihydrate	Others	Others
	Estradiol (β-Estradiol) hemihydrate 是主要女性性激素的类固醇激素。它能上调人类子宫内膜干细胞 (hEnSCs) 的神经标志物表达，促进神经分化，适用于癌症、神经退行性疾病和神经组织工程研究。
T36917	Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)	Others	Others
	Ethynyl estradiol 3-β-D-glucuronide is a metabolite of ethynyl estradiol that can be detected in urine.1,2It is used as a marker of estrogen contamination in fresh and saltwater.2 1.Hadd, H.E., Slikker, W., Jr., and Helton, E.D.The synthesis and characterization of the glucopyranosiduronic acids of 17a-ethynylestradiol-17bJ. Steroid Biochem.13(9)1107-1114(1980) 2.Griffith, D.R., Soule, M.C.K., Eglinton, T.I., et al.Steroidal estrogen sources in a sewage-impacted coastal oceanEnviron. Sci.: Proce...
T36807	Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)	Others	Others
	Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2 ...
T18876	β-Estradiol-6-CMO-PEG3-biotin	Others; ADC Linker	Antibody-drug Conjugate/ADC Related; Others
	β-Estradiol-6-CMO-PEG3-biotin serves as a cleavable 3-unit PEG ADC linker for the synthesis of antibody-drug conjugates (ADCs)[1].
T18877	β-Estradiol-6-one 6-(O-carboxymethyloxime)	Others	Others
	β-Estradiol-6-one 6-(O-carboxymethyloxime) is an alkyl chain-based PROTAC linker utilized for PROTAC synthesis[1].

化合物

beta-Estradiol 17-hemisuccinate

Cat.No: T9604

Target: Estrogen Receptor/ERR

Estradiol dipropionate

Cat.No: T2231

Synonym: 17-Beta-Estradiol-3,17-Dipropionate,3,17-二丙酸-17-BETA-雌二酯,二丙酸雌二醇

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Progesterone Receptor

Estradiol hemihydrate

Cat.No: T72390

Synonym: 17β-Oestradiol hemihydrate,β-Estradiol hemihydrate ; 17β-Estradiol hemihydrate ; 17β-Oestradiol hemihydrate,17β-Estradiol hemihydrate,β-Estradiol hemihydrate

Target: Others

Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)

Cat.No: T36917

Target: Others

Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)

Cat.No: T36807

Target: Others

β-Estradiol-6-CMO-PEG3-biotin

Cat.No: T18876

Target: Others, ADC Linker

β-Estradiol-6-one 6-(O-carboxymethyloxime)

Cat.No: T18877

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T1048	Estradiol 雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Estradiol (E2) 是一种天然的类固醇性激素，对于女性生育能力和第二性征的维持至关重要。Estradiol 通过雌激素受体 β (ERβ) 上调 IL-6 表达。
T7299	β-Estradiol 17-acetate β-雌二醇 17-乙酸酯,17-乙酸-17-BETA-雌二酯,beta-estradiol 17-acetate,1,3,5(10)-Estratriene-3,17β-diol 17-acetate	Estrogen Receptor/ERR; Others	Endocrinology/Hormones; Others
	β-Estradiol 17-acetate (1,3,5(10)-Estratriene-3,17β-diol 17-acetate) 是一种雌二醇代谢物。
T1571	Estriol NSC-12169,Oestriol,雌三醇	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; MRP; Endogenous Metabolite	Endocrinology/Hormones; Immunology/Inflammation; Metabolism
	Estriol (Oestriol) 是G 蛋白偶联雌激素受体拮抗剂，能够作用于雌激素受体阴性乳腺癌细胞。

天然产物

Cat.No: T1048

Synonym: 雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

β-Estradiol 17-acetate

Cat.No: T7299

Synonym: β-雌二醇 17-乙酸酯,17-乙酸-17-BETA-雌二酯,beta-estradiol 17-acetate,1,3,5(10)-Estratriene-3,17β-diol 17-acetate

Target: Estrogen Receptor/ERR, Others

Cat.No: T1571

Synonym: NSC-12169,Oestriol,雌三醇

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, MRP, Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01302	HSD17B1 Protein, Human, Recombinant (His & Myc) Placental 17-beta-hydroxysteroid dehydrogenase,Shor...	Human	E. coli
	Favors the reduction of estrogens and androgens. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2). Also has 20-alpha-HSD activity. Uses preferentially NADH. HSD17B1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 42.3 kDa and the accession number is P14061.
TMPH-01303	HSD17B11 Protein, Human, Recombinant (His & Myc) Estradiol 17-beta-dehydrogenase 11,HSD17B1...	Human	E. coli
	Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. HSD17B11 Prot...
TMPY-01660	SULT1E1 Protein, Human, Recombinant (His) ST1E1,EST,sulfotransferase family 1E member 1,EST-1,STE,MGC3...	Human	E. coli
	Estrogen sulfotransferase, also known as Sulfotransferase, estrogen-preferring, Sulfotransferase 1E1, SULT1E1 and ST1E1, is a cytoplasm enzyme that belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. SULT1E1 may control the level of the estrogen receptor by sulfurylating free estradio...
TMPJ-01382	HSPB8 Protein, Human, Recombinant (His) Small stress protein-like protein HSP22,CRYAC,E2IG1,Alpha-cr...	Human	E. coli
	Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity，appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have bee...

重组蛋白

HSD17B1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01302

Species: Human

Expression System: E. coli

HSD17B11 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01303

Species: Human

Expression System: E. coli

SULT1E1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01660

Species: Human

Expression System: E. coli

HSPB8 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01382

Species: Human

Expression System: E. coli

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0035	16α-Hydroxy-17β-estradiol-2,4-d2
	16α-Hydroxy-17β-estradiol-2,4-d2 是 Estriol 的氘代化合物。Estriol 的 CAS 号为 50-27-1。Estriol 是G蛋白偶联雌激素受体拮抗剂，能够作用于雌激素受体阴性乳腺癌细胞。
TMIJ-0280	Estriol-d3
	Estriol-d3 是 Estriol 的氘代化合物。Estriol 的 CAS 号为 50-27-1。Estriol 是G蛋白偶联雌激素受体拮抗剂，能够作用于雌激素受体阴性乳腺癌细胞。

同位素标记化合物

16α-Hydroxy-17β-estradiol-2,4-d2

Cat.No: TMIJ-0035

Cat.No: TMIJ-0280

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