Azidoethyl-SS-propionicacid is an ADC linker, specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. It possesses cleavable properties, allowing for the controlled release of drug payloads.
Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 4 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
Maleimido-tri(ethylene glycol)-propionicacid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Maleimido-tri(ethylene glycol)-propionicacid is used for the preparation of neolymphostin-based ADC precursors for site-spec
Propargyl-PEG1-SS-PEG1-acid is a two-unit polyethylene glycol (PEG) linker that is cleavable and commonly employed in the synthesis of antibody-drug conjugates (ADCs) [1].
Aminoethyl-SS-propionicacid is an ADC linker compound employed in ADC synthesis [1]. It functions as a cleavable linker in the conjugation of antibodies with drugs, allowing for targeted drug delivery.
Fmoc-NH-ethyl-SS-propionic NHS ester is a cleavable linker for antibody-drug conjugates (ADCs)[1]. It is employed in the synthesis of ADCs, facilitating the covalent attachment of drugs to antibodies through the formation of stable amide bonds.
Mal-NH-ethyl-SS-propionicacid, a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs)[1], plays a crucial role in the modulation of drug release from the conjugate.
Azidoethyl-SS-PEG2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Boc-amino-PEG3-SS-acid is a three-unit polyethylene glycol (PEG) linker with cleavable properties. It is commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].
Amino-PEG3-SS-acid is a three-unit polyethylene glycol (PEG) linker that is cleavable. It is commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].
Bis-(PEG6-acid)-SS is a cleavable linker composed of a six-unit PEG (polyethylene glycol) moiety. This linker is specifically employed in the synthesis of antibody-drug conjugates (ADCs)[1].