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Search Results for " anti-carcinogenic "

Targets Recommended: Others

5

抑制剂 & 化合物

8

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T22309	2,5-Dimethyl-3(2H)-furanone 2,5-二甲基-3(2H)-呋喃酮,2,5-Dimethyl-2,3-dihydrofuran-3-one	Others	Others
	2,5-Dimethyl-3(2H)-furanone (2,5-Dimethyl-2,3-dihydrofuran-3-one) 是一种调味物质，无遗传毒性。
T1765	Erastin	Ferroptosis; VDAC	Apoptosis; Membrane transporter/Ion channel
	Erastin 是一种作用于线粒体 VDAC 的铁死亡激活剂，具有 ROS 和铁依赖性。Erastin 具有抗肿瘤活性，选择性作用于 RAS 致癌突变的肿瘤细胞。该产品在溶液中不稳定，建议现配现用。
T23614	Achillin NSC 156236,NSC156236,NSC-156236	Others	Others
	Achillin is a compound isolated from herbs. It may have anti-inflammatory and anti-carcinogenic activities.
T23797	Bis(diazoacetyl)butane 1,4-Bis-diazoacetylbutane,Supermutagen,1,4-Bis(diazoacetyl)butane,DAB (mutagen)	Others	Others
	Bis(diazoacetyl)butane is a mutagen and traditionally related to radio-mimetic chemical mutagens due to the similarity of appearance of mutagenic action of this mutagen and physical mutagens. It also has anti-tumor and carcinogenic activity.
T73862	Almurtide	Others	Others
	Almurtide (nor-MDP)是一种来源于胞壁酰二肽的化合物，展现出抗炎及抗肿瘤的特性。此外，Almurtide可有效防护小鼠免受铜绿假单胞菌腹腔内感染和白色念珠菌静脉感染，亦对致癌性Friend白血病病毒表现出抑制力。

化合物

2,5-Dimethyl-3(2H)-furanone

Cat.No: T22309

Synonym: 2,5-二甲基-3(2H)-呋喃酮,2,5-Dimethyl-2,3-dihydrofuran-3-one

Target: Others

Cat.No: T1765

Target: Ferroptosis, VDAC

Cat.No: T23614

Synonym: NSC 156236,NSC156236,NSC-156236

Target: Others

Bis(diazoacetyl)butane

Cat.No: T23797

Synonym: 1,4-Bis-diazoacetylbutane,Supermutagen,1,4-Bis(diazoacetyl)butane,DAB (mutagen)

Target: Others

Cat.No: T73862

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2901	Daidzin NPI-031D,大豆苷,Daidzein 7-O-glucoside,Daidzoside,黄豆苷,Daidzein 7-glucoside	Dehydrogenase; Reverse Transcriptase; Mitochondrial Metabolism	Metabolism; Microbiology/Virology
	Daidzin (Daidzoside) 是从大豆中分离出来的一种异黄酮，具有抗氧化、抗癌和抗动脉粥样硬化的活性。
TN1097	β-Boswellic acid Beta-boswellic acid,β-乳香酸	Lipoxygenase; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	β-Boswellic acid (Beta-boswellic acid) 是从乳香的树胶脂中分离出来的一种天然产物。它是 5-脂氧合酶(5-LO) 产物形成的非还原型抑制剂，其直接与 5-LO 相互作用或阻断其易位。具有抗癌、抗肿瘤和抗高血脂活性。
T1035	Hesperidin 橙皮甙,Hesperetin 7-rutinoside,Cirantin,橙皮苷	Apoptosis; Reactive Oxygen Species; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Hesperidin (Cirantin) 属于黄烷酮糖苷类天然产物，广泛存在于柑橘类水果中。Hesperidin 具有抗氧化活性、抗肿瘤活性和抗过敏活性。
T4115	Auraptene 橙皮油内酯,7-geranyloxycoumarin,橙皮油素	MMP; BACE	Neuroscience; Proteases/Proteasome
	Auraptene 是一种丰富的天然香叶氧基香豆素。它能够抑制基质金属蛋白酶 2 以及关键炎症因子，包括 IL-6，IL-8 和趋化因子 (C-C 基序) 配体-5 (CCL5）的分泌。
TN2926	3-Epicabraleahydroxylactone	Others	Others
	3-Epicabraleahydroxylactone has anti-tumor promoting effect, it has anti-carcinogenic activity by the inhibitory effect on the induction of Epstein-Barr virus early antigen(EBV-EA) by the tumor promoter.
T77201	Rutin trihydrate	Others	Others
	Rutin (Rutoside) trihydrate 是多功能天然黄酮苷，展现出抗氧化、抗炎、抗糖尿病及抗癌效果。此外，该化合物还具有心脏保护和神经保护活性。
TN4695	Odorine	Others	Others
	Odorine has potent anti-carcinogenic effect by inhibiting both the initiation and promotion stages of two-stage skin carcinogenesis. It was found to inhibit the growth of the vinblastine-resistant KB cells by enhancing the anticancer activity of vinblastine.
TN3070	4beta-Hydroxywithanolide E	PARP; HSP; NF-κB; COX	Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	4beta-Hydroxywithanolide E(4bHWE) can inhibit the growth of colon cancer monolayer and spheroid cultures, it assert its anti-tumor activity in carcinogenic progression and develop into a dietary chemopreventive agent, it affects alternative splicing by mo

天然产物

Cat.No: T2901

Synonym: NPI-031D,大豆苷,Daidzein 7-O-glucoside,Daidzoside,黄豆苷,Daidzein 7-glucoside

Target: Dehydrogenase, Reverse Transcriptase, Mitochondrial Metabolism

β-Boswellic acid

Cat.No: TN1097

Synonym: Beta-boswellic acid,β-乳香酸

Target: Lipoxygenase, DNA/RNA Synthesis

Cat.No: T1035

Synonym: 橙皮甙,Hesperetin 7-rutinoside,Cirantin,橙皮苷

Target: Apoptosis, Reactive Oxygen Species, Endogenous Metabolite, Autophagy

Cat.No: T4115

Synonym: 橙皮油内酯,7-geranyloxycoumarin,橙皮油素

Target: MMP, BACE

3-Epicabraleahydroxylactone

Cat.No: TN2926

Target: Others

Rutin trihydrate

Cat.No: T77201

Target: Others

Cat.No: TN4695

Target: Others

4beta-Hydroxywithanolide E

Cat.No: TN3070

Target: PARP, HSP, NF-κB, COX

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