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Search Results for " anionic "

Targets Recommended: Others

22

抑制剂 & 化合物

12

天然产物

9

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T36587	APTS 8-Aminopyrene-1,3,6-trisulfonic acid trisodium	Others	Others
	8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt 是一种阴离子荧光染料，用作葡萄糖传感和检测其他糖类的报告分子。激发/发射光谱为 425/503 nm。它可以在溶液中使用，也可以通过还原胺化连接醛官能化单体来固定，而不会显著改变荧光强度。
T12950	Sodium laureth sulfate Sodium lauryl polyoxyethylene ether sulfate,月桂醇聚氧乙烯醚硫酸酯钠盐	Others	Others
	Sodium laureth sulfate (Sodium lauryl polyoxyethylene ether sulfate) 是一种阴离子活性剂，具有优良的去污，分散，乳化，润湿等性能。
TF0112	DPPS 12-Dipalmitoyl-sn-glycero-3-PS sodium salt,DPPS-Na	Others	Others
	DPPS (12-Dipalmitoyl-sn-glycero-3-PS sodium salt) 是一种阴离子二酰基磷脂，是磷脂酰丝氨酸(PS)的一种形式，是一种位于细胞膜内小叶的带负电荷的磷脂。DPPS 被用来制作阳离子囊泡和脂质体。
T72054	SLC26A3-IN-1	transporter	Metabolism
	SLC26A3-IN-1 是一种阴离子交换蛋白 SLC26A3 的抑制剂，IC50值为340 nM。SLC26A3 属于溶质载体 (SLC) 蛋白，是 SLC26 家族成员之一。SLC26 家族对氯化物、碳酸氢盐、硫酸盐和草酸盐具有广泛的阴离子特异性。SLC26A3 在腺瘤 (DRA) 中下调，参与氯化物和草酸盐的肠道吸收且与氯离子丢失性腹泻有关。
T83672	TTAPE-Me 1,1,2,2-tetrakis[4-(2-Trimethylammonioethoxy)-phenylethene
	TTAPE-Me是一种聚集诱导发光(AIE)荧光团。它被用于检测阴离子磷脂，包括心磷脂、磷脂酰甘油(PG)和磷脂酰丝氨酸(PS)、核酸，以及阴离子多糖肝素。
T70465	Mf 268	Others	Others
	Mf 268 is a pseudo-reversible carbamate-type inhibitor which interacts with the catalytic and regulatory anionic site of the enzyme.
TP1866	β-Amyloid (1-11) β-amyloid 1-11
	Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid of Alzheimer’s disease patients.
T39438	Lithium dodecyl sulfate	Others	Others
	Lithium dodecyl sulfate is an anionic detergent and surfactant, suitable as a substitute for sodium dodecyl sulfate (SDS) in electrophoresis applications performed under lower temperatures. Lithium dodecyl sulfate is also applicable in the synthesis of nanomaterials and chromatography processes.
T84677	Tetramyristoylcardiolipin TMCL	Others	Others
	Tetramyristoylcardiolipin (TMCL) 是一种阴离子脂质，主要用于研究细胞膜功能和药物传递。
T62541	AChE-IN-22	Others	Others
	AChE-IN-22 (compound 10q) 是一种乙酰胆碱酯酶 (AChE) 的选择性抑制剂，能够作用于 AChE (IC50: 0.88 μM) 和 BuChE (IC50: 10 μM)。AChE-IN-22 能够同时与 AChE 的 CAS (catalytic active site) 和 PAS (peripheral anionic site) 位点结合，可用于研究阿尔茨海默病。
T74991	Dual AChE-MAO B-IN-3	Others	Others
	Dual AChE-MAO B-IN-3 (compound C10) 是一种有效的双AChE/MAO-B 抑制剂，IC50值分别为 0.58 和 0.41 μM。Dual AChE-MAO B-IN-3 是一种双结合抑制剂，能与AChE 的催化阴离子位点和外周阴离子位点结合。Dual AChE-MAO B-IN-3 可以用于阿尔茨海默病 (AD) 的研究。
T73733	(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium	Others	Others
	(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) 为阴离子磷脂, 主要应用于药物递送及脂质体合成。
T78828	AChE/BChE-IN-15	Others	Others
	AChE/BChE-IN-15 (Compound 6d) 是一种抑制剂，针对AChE/BChE的IC50值为20 nM和220 nM。该化合物能够与AChE和BChE的活性位点中的催化阴离子位点(CAS)及外周阴离子位点(PAS)相结合，适用于阿尔茨海默病的研究。
T84863	Tridecafluorohexane-1-sulfonic acid potassium salt	Others	Others
	Tridecafluorohexane-1-sulfonic acid potassium salt是全氟阴离子表面活性剂，应用于电镀作为铬雾抑制剂、润湿剂，以及氟蛋白泡沫灭火剂的添加剂。
T75340	4-Methylumbelliferyl phosphate disodium
	4-Methylumbelliferyl phosphate disodium (4-MUP) 是一种阴离子有机磷酸酯，作为酸性和碱性磷酸酶（phosphatase）的荧光底物，同时也用作神经毒剂模拟剂。
T80045	Defensin HNP-3 human	Antibiotic	Microbiology/Virology
	Defensin HNP-3 human 是一种具有抑制金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌活性的细胞毒性抗生素肽。该肽原先以94个氨基酸的preproHNP(1-94)形式合成，随后水解为proHNP(20-94)，最终通过去除阴离子前体转化为成熟形式的HNP(65-94)。
TP2510	CAY10679 N,N'-bis(glycyl-glycine)-hexane-1,6-Dicarboxyamide	Others	Others
	CAY10679, an anionic oligopeptide-based bola-amphiphile, features a central hexane segment bordered by a glycylglycine group at each end, establishing pronounced hydrophilic and hydrophobic regions. This amphiphilic peptide's propensity for self-assembling into microtubes in aqueous acidic solutions has been explored. Such bola-amphiphiles hold significant potential in the development of nanotubes, nanovesicles, nanowires, and nanocarriers for drug delivery, among various bionanotechnology appli...
T75762	LAH4 TFA
	LAH4 TFA是一种两亲性肽抗生素，以α螺旋形式表现出显著的抗菌(antimicrobial)、核酸转染(nucleic acid transfection)及细胞穿透能力。它在传递质粒DNA方面显示出较高效能，并对细菌外膜中的阴离子脂质展现强烈亲和力。
T83406	2,3-Diphospho-D-glyceric acid pentasodium salt 2,3-DPG pentasodium salt	Others	Others
	2,3-Diphospho-D-glyceric acid pentasodium salt 是一种聚磷化合物，具有明显的阴离子性质。它在红细胞的凹中心起作用，通过结合血红蛋白降低氧亲和力。作为血管钙化 (VC) 的内源性选择性抑制剂，2,3-Diphospho-D-glyceric acid 能显著推迟结晶钙蛋白颗粒 (CPP) 的生成，并在小鼠血管平滑肌细胞系 (MOVAS) 中抑制钙化作用，同时不引起细胞毒性。
T83314	4-Methylumbelliferyl palmitate
	4-Methylumbelliferyl palmitate 是用于测量人白细胞中酸性脂肪酶的优良荧光探针。该化合物的荧光特性受pH值和溶剂类型的显著影响。在近中性水溶液中，4-Methylumbelliferyl palmitate 以中性形态存在，并在445 nm发射较强荧光；而在微弱碱性环境中，则以阴离子形态存在，同样在445 nm处展现较强的荧光。
T82243	hAChE-IN-5	GSK-3	PI3K/Akt/mTOR signaling; Stem Cells
	hAChE-IN-5（化合物49）是一种同时针对hAChE和hBuChE的有效抑制剂，其IC50值均为0.17 μM。此外，hAChE-IN-5对GSK3β同样展现出良好的抑制活性，IC50值为0.21 μM。作为tau蛋白聚集和Aβ1-42自聚集的抑制剂，hAChE-IN-5能够结合PAS，进而阻止Aβ依赖的神经毒性。其能穿透血脑屏障（BBB），显示出成为多靶点抗阿尔茨海默病药物研究的潜力。
T35578	Phosphatidylserines (sodium salt) Phosphatidylserines (sodium salt),L-α-Phosphatidylserine	Others	Others
	Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on the inner leaflet of the cell membrane. It is biosynthesized from phosphatidylcholine or phosphatidylethanolamine by phosphatidyl synthase 1 (PSS1) or PSS2, respectively, in the endoplasmic reticulum (ER) and can be reversibly converted back by the same enzymes. It can also be irre...

化合物

Cat.No: T36587

Synonym: 8-Aminopyrene-1,3,6-trisulfonic acid trisodium

Target: Others

Sodium laureth sulfate

Cat.No: T12950

Synonym: Sodium lauryl polyoxyethylene ether sulfate,月桂醇聚氧乙烯醚硫酸酯钠盐

Target: Others

Cat.No: TF0112

Synonym: 12-Dipalmitoyl-sn-glycero-3-PS sodium salt,DPPS-Na

Target: Others

Cat.No: T72054

Target: transporter

Cat.No: T83672

Synonym: 1,1,2,2-tetrakis[4-(2-Trimethylammonioethoxy)-phenylethene

Cat.No: T70465

Target: Others

β-Amyloid (1-11)

Cat.No: TP1866

Synonym: β-amyloid 1-11

Lithium dodecyl sulfate

Cat.No: T39438

Target: Others

Tetramyristoylcardiolipin

Cat.No: T84677

Synonym: TMCL

Target: Others

Cat.No: T62541

Target: Others

Dual AChE-MAO B-IN-3

Cat.No: T74991

Target: Others

(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium

Cat.No: T73733

Target: Others

AChE/BChE-IN-15

Cat.No: T78828

Target: Others

Tridecafluorohexane-1-sulfonic acid potassium salt

Cat.No: T84863

Target: Others

4-Methylumbelliferyl phosphate disodium

Cat.No: T75340

Defensin HNP-3 human

Cat.No: T80045

Target: Antibiotic

Cat.No: TP2510

Synonym: N,N'-bis(glycyl-glycine)-hexane-1,6-Dicarboxyamide

Target: Others

Cat.No: T75762

2,3-Diphospho-D-glyceric acid pentasodium salt

Cat.No: T83406

Synonym: 2,3-DPG pentasodium salt

Target: Others

4-Methylumbelliferyl palmitate

Cat.No: T83314

Cat.No: T82243

Target: GSK-3

Phosphatidylserines (sodium salt)

Cat.No: T35578

Synonym: Phosphatidylserines (sodium salt),L-α-Phosphatidylserine

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T5692	Pyrroloquinoline quinone	Others; Endogenous Metabolite	Metabolism; Others
	Pyrroloquinoline quinone 是氧化还原辅助因子，一种阴离子型氧化还原循环原醌。它是哺乳动物的必需营养素，对免疫功能很重要。它是从嗜甲基细菌的培养物中分离的，也存在于哺乳动物的组织。
T3603	Sodium lauryl sulfoacetate 月桂醇磺基乙酸酯钠,鱼腥草,新鱼腥草素钠,Sodium houttuyfonate	NF-κB; MAPK	MAPK; NF-κB
	Sodium lauryl sulfoacetate (Sodium houttuyfonate) 是一种植物来源的固体阴离子表面活性剂，也是一种具有抗免疫抑制作用的免疫佐剂。
T5693	Pyrroloquinoline quinone disodium salt 吡咯喹啉醌二钠盐,Methoxatin disodium salt	Others; Endogenous Metabolite	Metabolism; Others
	Pyrroloquinoline quinone disodium salt (Methoxatin disodium salt) 一种阴离子型氧化还原循环原醌，作为氧化还原辅助因子。它是从嗜甲基细菌的培养物中分离的，也存在于哺乳动物的组织。它是哺乳动物的必需营养素，对免疫功能很重要。
T5666	Dipotassium glycyrrhizinate	Virus Protease	Microbiology/Virology
	Dipotassium glycyrrhizinate 是一种具有抗过敏和抗炎活性的阴离子表面活性剂。
TN7244	Egg PG Phosphatidylglycerols(egg)
	Egg PG(Phosphatidylglycerols(egg)) 是一种食物和生物组织的主要磷脂酰甘油之一，常存在于细菌和动物细胞的膜中，可作为 sPMCA，反应中的阴离子磷脂底物。
TN2349	Taurodeoxycholate sodium salt Sodium taurodeoxylate,牛磺脱氧胆酸钠	Endogenous Metabolite	Metabolism
	Taurodeoxycholate sodium salt (Sodium taurodeoxylate) 是胆盐相关的阴离子洗涤剂，用于分离膜蛋白，包括线粒体内膜蛋白。它还可以抑制各种炎症反应。
T5004	Hyaluronic acid sodium 透明质酸钠,Sodium Hyaluronate	Others	Others
	Hyaluronic acid sodium (Sodium Hyaluronate) 是一种生物聚合物，由二糖的重复单元组成，应用领域广泛。
T38141	Glycerophospholipids, cephalins Phosphatidylethanolamines (egg)
	Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物，在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用，可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。
T4825	D-(+)-Xylose D(+)-Xylose,木糖,(+)-Xylose,Wood sugar	Endogenous Metabolite	Metabolism
	D-(+)-Xylose (Wood sugar) 是一种是一种戊醛糖，其化学式为C5H10O5，甜度为蔗糖的40%。木糖也存在于结缔组织的粘多糖中，有时也存在于尿液中。
T20854	Isethionic acid Hydroxyethylsulfonic acid,Ethanolsulfonic acid	Others	Others
	Isethionic acid, a major metabolite in F. cylindrus, is an organosulfur compound containing a short-chain alkane sulfonate linked to a hydroxyl group. It is a water-soluble liquid for the manufacture of mild, biodegradable, and high-foaming anionic surfac
T29607	Acid Red 88 11391 Red,Eniacid Fast Red A,Peony,Red No. 506
	Acid red 88 is an anionic dye with potentially useful photocatalytic research applications. Acid red 88 has been used to determine the effect of Au deposition on ZnO photocatalytic activity under visible light. Additionally, the photocatalyst Au-TiO2 was
T35577	Phosphatidylserines (bovine)	Others	Others
	Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on the inner leaflet of the cell membrane. It is biosynthesized from phosphatidylcholine or phosphatidylethanolamine by phosphatidyl synthase 1 (PSS1) or PSS2, respectively, in the endoplasmic reticulum and can be reversibly converted back by the same enzymes. It can also be irreversi...

天然产物

Pyrroloquinoline quinone

Cat.No: T5692

Target: Others, Endogenous Metabolite

Sodium lauryl sulfoacetate

Cat.No: T3603

Synonym: 月桂醇磺基乙酸酯钠,鱼腥草,新鱼腥草素钠,Sodium houttuyfonate

Target: NF-κB, MAPK

Pyrroloquinoline quinone disodium salt

Cat.No: T5693

Synonym: 吡咯喹啉醌二钠盐,Methoxatin disodium salt

Target: Others, Endogenous Metabolite

Dipotassium glycyrrhizinate

Cat.No: T5666

Target: Virus Protease

Cat.No: TN7244

Synonym: Phosphatidylglycerols(egg)

Taurodeoxycholate sodium salt

Cat.No: TN2349

Synonym: Sodium taurodeoxylate,牛磺脱氧胆酸钠

Target: Endogenous Metabolite

Hyaluronic acid sodium

Cat.No: T5004

Synonym: 透明质酸钠,Sodium Hyaluronate

Target: Others

Glycerophospholipids, cephalins

Cat.No: T38141

Synonym: Phosphatidylethanolamines (egg)

Cat.No: T4825

Synonym: D(+)-Xylose,木糖,(+)-Xylose,Wood sugar

Target: Endogenous Metabolite

Isethionic acid

Cat.No: T20854

Synonym: Hydroxyethylsulfonic acid,Ethanolsulfonic acid

Target: Others

Cat.No: T29607

Synonym: 11391 Red,Eniacid Fast Red A,Peony,Red No. 506

Phosphatidylserines (bovine)

Cat.No: T35577

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00480	Anionic trypsin Protein, Canine, Recombinant (His & SUMO) Anionic trypsin,EC:3.4.21.4	Canine	E. coli
	Anionic trypsin Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-03244	Anionic trypsin-2 Protein, Rat, Recombinant (His) Anionic trypsin II,Pretrypsinogen II,Prss2,Try2,	Rat	P. pastoris (Yeast)
	N/A. Anionic trypsin-2 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 25.3 kDa and the accession number is P00763.
TMPH-03242	Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His) Pretrypsinogen I,Cationic trypsinogen,Try1,Beta-trypsin,Seri...	Rat	E. coli
	N/A. Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 27.2 kDa and the accession number is P00762.
TMPH-03243	Anionic trypsin-1 Protein, Rat, Recombinant (His) Pretrypsinogen I,Anionic trypsin I,Try1,Trp1,Prss1,...	Rat	P. pastoris (Yeast)
	N/A. Anionic trypsin-1 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is P00762.
TMPH-00484	Cationic trypsin Protein, Canine, Recombinant (His & SUMO) TRP1,Serine protease 1,PRSS1,TRY1,Pretrypsinogen I,Anion...	Canine	E. coli
	Cationic trypsin Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02255	Trypsin-2 Protein, Human, Recombinant (K23Q & S167G, His) Anionic trypsinogen,PRSS2,Trypsin II,Trypsin-2,Seri...	Human	E. coli
	In the ileum, may be involved in defensin processing, including DEFA5.
TMPH-02254	Trypsin-1 Protein, Human, Recombinant (His & Myc) Trypsin-1,PRSS1,Serine protease 1,Beta-trypsin,Trypsin I,	Human	E. coli
	Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates.
TMPH-03750	SLC7A11 Protein, Human, Recombinant (His) SLC7A11,Calcium channel blocker resistance protein CCBR1,Sol...	Human	E. coli
	Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.
TMPY-01580	PRSS2 Protein, Mouse, Recombinant (His) Tesp4,protease, serine 2,Try2,Ta,TRY8,TRYP,Prss2	Mouse	HEK293 Cells
	Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein that belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists of a signal peptide (residues 1-15), a pro region (residues 16-23), and a proteolytically active mature chain (residues 24-247). PRSS2 contains one peptidase S1 domain. It is secreted into the duodenum, hydrolysing peptides into their smaller building blocks, which is necessary ...

重组蛋白

Anionic trypsin Protein, Canine, Recombinant (His & SUMO)

Cat.No: TMPH-00480

Species: Canine

Expression System: E. coli

Anionic trypsin-2 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03244

Species: Rat

Expression System: P. pastoris (Yeast)

Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPH-03242

Species: Rat

Expression System: E. coli

Anionic trypsin-1 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03243

Species: Rat

Expression System: P. pastoris (Yeast)

Cationic trypsin Protein, Canine, Recombinant (His & SUMO)

Cat.No: TMPH-00484

Species: Canine

Expression System: E. coli

Trypsin-2 Protein, Human, Recombinant (K23Q & S167G, His)

Cat.No: TMPH-02255

Species: Human

Expression System: E. coli

Trypsin-1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02254

Species: Human

Expression System: E. coli

SLC7A11 Protein, Human, Recombinant (His)

Cat.No: TMPH-03750

Species: Human

Expression System: E. coli

PRSS2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01580

Species: Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMID-0294	Taurodeoxycholic Acid-d4 Sodium Salt
	Taurodeoxycholic Acid-d4 Sodium Salt 是 Taurodeoxycholic Acid Sodium Salt 的氘代化合物。Taurodeoxycholic Acid Sodium Salt 的 CAS 号为 1180-95-6。Taurodeoxycholate sodium salt 是胆盐相关的阴离子洗涤剂，用于分离膜蛋白，包括线粒体内膜蛋白。它还可以抑制各种炎症反应。

同位素标记化合物

Taurodeoxycholic Acid-d4 Sodium Salt

Cat.No: TMID-0294

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上海市静安区江场三路238号8楼