alx 404c

Activated Protein C (390-404), human acetate (Activated Protein C ) 抑制 APC 抗凝活性。

ALX40-4C is a small peptide inhibitor of the chemokine receptor CXCR4 that can inhibit X4 strains of HIV-1.

Activated Protein C (390-404), human, a peptide derived from the vitamin K-dependent serine protease, effectively suppresses the anticoagulant activity of APC[1].

The peptide region containing residues 390-404 in Activated Protein C (APC) is essential for anticoagulant activity and is available for interaction with antibodies or with other proteins, such as the macromolecular substrates Factors Va or VIIIa. APC reg

ALX 40-4C acetate 是趋化因子受体 (Ki = 1 μM) 的 CXCR4 抑制剂，可抑制 HIV-1 X4 株的复制。 ALX 40-4C acetate 是 APJ 受体的拮抗剂 (IC50 = 2.9 μM)。

Alx40-4C trifluoroacetate is a chemokine receptor (CXCR4) inhibitor, which inhibits the binding of sdf-1 to CXCR4.Alx40-4ctrifluoroacetate was also an APJ receptor antagonist with an IC50 value of 2.9 M.