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Search Results for " alcohol-preferring "
Targets Recommended: Dehydrogenase

2

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T15022 CVT-10216

3-[[[3-[4-[(甲基磺酰基)氨基]苯基]-4-氧代-4H-苯并吡喃-7-基]氧基]甲基]苯甲酸

Dehydrogenase Metabolism
CVT-10216 是可逆的、选择性的醛脱氢酶 2(ALDH-2)抑制剂,IC50为 29 nM。对 ALDH-1的抑制作用较弱,IC50为 1.3 μM。 它可以减少偏爱酒精的大鼠过量饮酒,并表现出抗焦虑作用。
T38903 (S)-UFR2709

(S)-UFR2709

Others Others
(S)-UFR2709 is a competitive antagonist of the nicotinic acetylcholine receptor (nAChR), exhibiting a greater affinity for α4β2 nAChRs compared to α7 nAChRs. It effectively reduces anxiety and ethanol consumption, as well as ethanol preference, in alcohol-preferring rats. Additionally, (S)-UFR2709 functions as an anxiolytic agent and holds the potential for investigating nicotine addiction.

化合物

CVT-10216
Cat.No: T15022
Synonym: 3-[[[3-[4-[(甲基磺酰基)氨基]苯基]-4-氧代-4H-苯并吡喃-7-基]氧基]甲基]苯甲酸
Target: Dehydrogenase
(S)-UFR2709
Cat.No: T38903
Synonym: (S)-UFR2709
Target: Others
Cat. No. Product Name Species Expression System
TMPY-03330 BPHL Protein, Human, Recombinant (His)

biphenyl hydrolase-like (serine hydrolase),VACVASE,MCNAA,BPH...

Human E. coli
BPHL is a member of the serine protease family. BPHL is expressed large quantities in liver and kidney and in minor quantities in heart, intestine and skeletal muscle. BPHL is a specific alpha-amino acid ester hydrolase that prefers small, hydrophobic, and aromatic side chains and does not have a stringent requirement for the leaving group other than preferring a primary alcohol. It catalyzes the hydrolytic activation of amino acid ester prodrugs of nucleoside analogs such as valacyclovir ...

重组蛋白

BPHL Protein, Human, Recombinant (His)
Cat.No: TMPY-03330
Species: Human
Expression System: E. coli
TargetMol Loading
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