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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T34939 |
Triethyl aconitate
AI3 11238,AI311238,AI3-11238 |
Others | Others |
Triethyl aconitate is a biochemical. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5564 |
Tricarballylic acid
β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,三碳烯丙酸,Carballylic acid,Propane-1,2,3-tricarboxylic acid,丙三酸 |
aconitase; Mitochondrial Metabolism | Metabolism |
Tricarballylic acid (Carballylic acid) 是三碳烯丙酸酯的共轭酸,是一种乌头酸水合酶的竞争性抑制剂,其 Ki= 0.52 mM。 | |||
T4861 |
trans-Aconitic acid
|
ATPase; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism |
trans-Aconitic acid 是反式丙酮酸2-甲基转移酶的底物,存在于正常人尿液中,大量存在于 Reye 综合征和有机酸尿症。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02585 |
ACOD1 Protein, Mouse, Recombinant (His & Myc)
Cis-aconitate decarboxylase,Cis-aconitic acid decar... |
Mouse | Baculovirus Insect Cells |
Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the anti... | |||
TMPH-01098 |
ACOD1 Protein, Human, Recombinant (His)
Aconitate decarboxylase 1,IRG1,Cis-aconitate |
Human | E. coli |
ACOD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.6 kDa and the accession number is A6NK06. | |||
TMPY-02375 |
acnB Protein, E. coli, Recombinant
yacI,yacJ |
E. coli | E. coli |
Escherichia coli contains two major aconitases (Acns), AcnA and AcnB. They are distantly related monomeric Fe-S proteins that contain different arrangements of four structural domains. acnA is specifically subject to SoxRS-mediated activation, whereas acnB encodes the major aconitase that is synthesized earlier in the growth cycle than AcnA. It is concluded that AcnB is the major citric acid cycle enzyme. Aconitate hydratase 2 (acnB) catalyzes the isomerization of citrate to isocitrate via cis-a... |