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Search Results for " aconitate "
Targets Recommended: Others

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抑制剂 & 化合物

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天然产物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T34939 Triethyl aconitate

AI3 11238,AI311238,AI3-11238

Others Others
Triethyl aconitate is a biochemical.

化合物

Triethyl aconitate
Cat.No: T34939
Synonym: AI3 11238,AI311238,AI3-11238
Target: Others
Cat. No. Product Name Target Signaling Pathways
T5564 Tricarballylic acid

β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,三碳烯丙酸,Carballylic acid,Propane-1,2,3-tricarboxylic acid,丙三酸

aconitase; Mitochondrial Metabolism Metabolism
Tricarballylic acid (Carballylic acid) 是三碳烯丙酸酯的共轭酸,是一种乌头酸水合酶的竞争性抑制剂,其 Ki= 0.52 mM。
T4861 trans-Aconitic acid

ATPase; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism
trans-Aconitic acid 是反式丙酮酸2-甲基转移酶的底物,存在于正常人尿液中,大量存在于 Reye 综合征和有机酸尿症。

天然产物

Tricarballylic acid
Cat.No: T5564
Synonym: β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,三碳烯丙酸,Carballylic acid,Propane-1,2,3-tricarboxylic acid,丙三酸
Target: aconitase, Mitochondrial Metabolism
trans-Aconitic acid
Cat.No: T4861
Synonym:
Target: ATPase, Endogenous Metabolite
Cat. No. Product Name Species Expression System
TMPH-02585 ACOD1 Protein, Mouse, Recombinant (His & Myc)

Cis-aconitate decarboxylase,Cis-aconitic acid decar...

Mouse Baculovirus Insect Cells
Cis-aconitate decarboxylase that catalyzes production of itaconate and is involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the anti...
TMPH-01098 ACOD1 Protein, Human, Recombinant (His)

Aconitate decarboxylase 1,IRG1,Cis-aconitate

Human E. coli
ACOD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.6 kDa and the accession number is A6NK06.
TMPY-02375 acnB Protein, E. coli, Recombinant

yacI,yacJ

E. coli E. coli
Escherichia coli contains two major aconitases (Acns), AcnA and AcnB. They are distantly related monomeric Fe-S proteins that contain different arrangements of four structural domains. acnA is specifically subject to SoxRS-mediated activation, whereas acnB encodes the major aconitase that is synthesized earlier in the growth cycle than AcnA. It is concluded that AcnB is the major citric acid cycle enzyme. Aconitate hydratase 2 (acnB) catalyzes the isomerization of citrate to isocitrate via cis-a...

重组蛋白

ACOD1 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02585
Species: Mouse
Expression System: Baculovirus Insect Cells
ACOD1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01098
Species: Human
Expression System: E. coli
acnB Protein, E. coli, Recombinant
Cat.No: TMPY-02375
Species: E. coli
Expression System: E. coli
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