252
116
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Cat. No. | Product Name | ||
---|---|---|---|
L9420 | 外泌体相关化合物库 | 76 compounds | |
76 种外泌体相关的化合物,可以用于高通量和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8547 |
DCBA
|
Drug Metabolite | Metabolism |
DCBA 是驱虫剂 N-N-diethyl-meta-toluamide (DEET) 的代谢物。尿液中 DCBA 的浓度是评估 DEET 暴露程度的指标。 | |||
T8365 |
Methenamine Hippurate
|
Antibacterial | Microbiology/Virology |
Methenamine hippurate 是一种口服活性尿液广谱抗菌剂。它对大多数常见的尿路病原体有效。 | |||
T8802 |
2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-
2,4-Dioxaspiro[5.5]undec-8-ene, 3-(2-fur |
Serine Protease | Proteases/Proteasome |
2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) 是胰蛋白酶抑制剂(人尿 urinastatin protein moiety),作为尿胰蛋白酶抑制剂(UTI),是一种从健康人尿液中分离或合成产生的糖蛋白。 | |||
TP1158 |
Copper tripeptide
[N2-(N-甘氨酰-L-组氨酰)-L-赖氨酸]铜,GHK-Cu |
Others; Endogenous Metabolite | Metabolism; Others |
Copper tripeptide (GHK-Cu) 是天然存在的三肽,首先从人血浆中分离,但也能够在唾液和尿液中发现。它能够提高成纤维细胞中胶原蛋白,弹性蛋白,蛋白多糖和糖胺聚糖中信使 RNA 的产生。在伤口愈合期间,它能够通过蛋白水解从现有的细胞外蛋白质中除去,并且用作炎性和内皮细胞的化学引诱物。它是皮肤再生中多种细胞途径的天然调节剂。 | |||
T7826 |
6-Chloropurine riboside
|
Others | Others |
6-Chloropurine riboside (6-CPR)是一种嘌呤核苷类似物,已被发现具有广泛的生物活性。它可以抑制肿瘤细胞的生长并诱导其凋亡,还被证明具有抗炎、抗病毒和抗真菌的特性,也被发现具有神经保护作用,并已用于治疗神经疾病。 | |||
T9462 |
2-Amino-6-cyclopropylamino-9H-purine
|
Others | Others |
2-Amino-6-cyclopropylamino-9H-purine 是阿巴卡韦(abacavir) 的关键中间体,以氰基乙酸乙酯为原料,经亚硝化、盐酸胍在 EtONa 存在下环合、还原得到2,4,5-三氨基-6-羟基嘧啶 | |||
T37348 |
6-Chloro-7-deazapurine-β-D-riboside
|
Antifungal | Microbiology/Virology |
6-Chloro-7-deazapurine-β-D-riboside 是核苷的衍生物,显示出抗真菌活性。 | |||
TNU0758 |
2-Aminopurine-9-beta-D-(2’-deoxy)riboside
|
Others | Others |
2-Aminopurine-9-beta-D-(2’-deoxy)riboside 是2-Aminopurine 的衍生物。 | |||
T2201 |
6-Mercaptopurine hydrate
6-Mercaptopurine monohydrate,6-巯基嘌呤(一水合物),6-Mercaptopurine (6-MP) Monohydrate,6-巯基嘌呤 一水合物 |
Nucleoside Antimetabolite/Analog; Others; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others |
6-Mercaptopurine hydrate (6-Mercaptopurine monohydrate) 是一种核苷代谢抑制剂。它通过抑制嘌呤代谢来干扰核酸合成,通常与其他药物联合用于白血病的治疗或缓解维持计划。 | |||
T7470 |
6-Chloropurine
6-氯嘌呤,6-Chloro-9H-purine |
Others | Others |
6-Chloropurine (6-Chloro-9H-purine) 是一种制备9-烷基嘌呤和6-巯基嘌呤的中间体,是化学合成的砌块,具有抗肿瘤作用。 | |||
T0010 |
6-Mercaptopurine
6-巯基嘌呤,乐疾宁,6-MP,Mercaptopurine,6-巯基嘌呤 |
Nucleoside Antimetabolite/Analog; Others; Dehydrogenase; Endogenous Metabolite; Autophagy | Autophagy; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others |
6-Mercaptopurine (6-MP) 是一种具有免疫抑制特性的抗代谢物抗肿瘤剂。它通过抑制嘌呤代谢来干扰核酸合成,通常与其他药物联合用于白血病的治疗或缓解维持计划。 | |||
T26399 |
7-Methyl-6-mercaptopurine
7-Methyl-6-thiopurine,6-Mercapto-7-methylpurine |
Others | Others |
7-Methyl-6-mercaptopurine (7-Methyl-6-thiopurine) 是 PRPP 氨基转移酶的抑制剂,抑制 IMP 代谢并阻止嘌呤、DNA 和 RNA 合成。 | |||
T19836 |
2-Aminopurine
|
DNA/RNA Synthesis; PKA | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Tyrosine Kinase/Adaptors |
2-Aminopurine 是一种鸟苷和腺苷的荧光类似物,是基于荧光衰变的 DNA 结构探针。当它插入寡核苷酸后,其荧光会通过与天然碱基堆积而被高度淬灭。它可用于核酸的结构和动力学的探测。 | |||
T77200 |
2-Aminopurine dihydrochloride
|
||
2-Aminopurine dihydrochloride 是一种鸟苷的荧光类似物。2-Aminopurine dihydrochloride 可用作核酸结构和动力学的荧光探针。储存方式:避光。 | |||
T29902 |
Alphazurine A
|
||
Alphazurine A is a blue dye. | |||
TNU1368 |
2-Amino-8-hydroxypurine-9-beta-D-(2’,5’-di-O-acetyl-3’-deoxy)riboside
|
Others | Others |
2-Amino-8-hydroxypurine-9-beta-D-(2’,5’-di-O-acetyl-3’-deoxy)riboside 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 TNU1368,CAS号为 2389988-74-1。 | |||
TNU0733 |
9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-2,6-dichloropurine
|
Others | Others |
3’-O-Methyl nucleoside; Halo-nucleoside | |||
TNU0719 |
2-Amino-6-chloropurine-3’,5’-di-O-acetyl-2’-deoxyriboside
|
Others | Others |
Nucleoside - 2’-deoxy nucleoside; halo nucleoside | |||
T64613 |
2-Methoxy-1,7,9-trimethyl-7,9-dihydro-1H-purine-6,8-dione
|
Others | Others |
2-Methoxy-1,7,9-trimethyl-7,9-dihydro-1H-purine-6,8-dione 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64613。 | |||
T126442 |
N-Methyltaurine
|
Others | Others |
N-Methyltaurine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126442,CAS号为 107-68-6。 | |||
T76096 |
Purine nucleoside phosphorylase
|
Others | Others |
Purine nucleoside phosphorylase 是嘌呤代谢中的关键酶,参与嘌呤挽救途径。Purine nucleoside phosphorylase 缺乏导致 T 细胞功能受损。在无机正磷酸盐作为第二底物的存在下,Purine nucleoside phosphorylase 催化核糖和脱氧核糖核苷的糖苷键断裂,生成嘌呤碱和核糖(脱氧核糖)-1-磷酸。 | |||
TNU1411 |
2,6-Bis(4-morpholinyl)-9-b-D-ribofuranosyl-9H-purine
|
Others | Others |
Nucleoside Derivatives –6-Subtituted nucleosides;2-Substituted nucleosides | |||
TNU0757 |
2-Amino-6-chloropurine-9-beta-D-(2’-deoxy)riboside
|
Others | Others |
2-Amino-6-chloropurine-9-beta-D-(2'-deoxy)riboside is a 2'-Deoxy nucleoside; Halo-nucleoside. | |||
T75074 |
6-Methoxypurine-9-β-D-5’(R)-C-methylriboside
|
Others | Others |
6-Methoxypurine-9-β-D-5’(R)-C-methylriboside 是一种嘌呤碱基,属于次黄嘌呤似物,主要在肌肉组织中发现。作为黄嘌呤在嘌呤氧化酶作用下的代谢产物,次黄嘌呤具备显著的抗炎性质,并可作为内源性 poly(ADP-ribose) polymerase (PARP) 的抑制剂。其通过抑制 PARP 活性,防止过氧亚硝酸盐引起的线粒体去极化及次级超氧化物的产生,展现出细胞保护作用。同时,次黄嘌呤也被用作缺氧的生物标志物。 | |||
T83261 |
6-Methoxypurine arabinoside
Ara-m |
Others | Others |
6-Methoxypurine arabinoside (Ara-m) 是一种抗水痘-带状疱疹病毒(VZV)活性物质,具有对8株VZV 50%抑制浓度差异,在0.5 - 3 microM范围内。 | |||
TNU1353 |
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-2,5-di-O-acetyl-3-deoxy-3-fluoro-ribofuranosyl)purine
|
Others | Others |
2-Amino-7-propargyl-7,8-dihydro-8-oxo-9-(beta-D-2,5-di-O-acetyl-3-deoxy-3-fluoro-ribofuranosyl)purine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 TNU1353,CAS号为 2389986-90-5。 | |||
T71808 |
Tisopurine
|
Others | Others |
Tisopurine is a drug used in the treatment of gout in some countries. It reduces uric acid production through inhibiting an early stage in its production. | |||
TNU0914 |
6-Benzoylamino-9H-purine-9-acetic acid
|
Others | Others |
6-Benzoylamino-9H-purine-9-acetic acid is a PNA-related Derivative; PNA monomer. | |||
T69210 |
Chondrocurine
|
Others | Others |
Chondrocurine is a biochemical that Inhibits quick death of mice treated with bacillus Calmetta Guerin & elicited with lipopolysaccharide. | |||
T124470 |
N-Glyceryltaurine
|
Others | Others |
N-Glyceryltaurine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124470。 | |||
TNU0064 |
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine
|
Others | Others |
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-phenylpurine is a Nucleoside Derivative - Fluoro-modified nucleoside, 6-Modified purine nucleoside, 3'-Modified nucleoside. | |||
TNU0770 |
2-Amino-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)purine
|
Others | Others |
Fluoro-modified nucleoside; 6-De-aminopurine nucleoside | |||
TNU0086 |
Purine -9-beta-D-(2’-deoxy-2’-fluoro) arabinoriboside
|
Others | Others |
Purine -9-beta-D-(2'-deoxy-2'-fluoro) arabinoriboside is a Fluoro-modified nucleoside; 6-De-aminopurine nucleoside; Arabino-nucleoside. | |||
TNU0344 |
6-(1-Piperizinyl)-9-beta-D-ribofuranosyl)-9H-purine
|
Others | Others |
6-(1-Piperizinyl)-9-beta-D-ribofuranosyl)-9H-purine is a Nucleoside Derivative - 6-Modified purine nucleoside. | |||
TNU0068 |
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine
|
Others | Others |
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine is a Nucleoside Derivative - Fluoro-modified nucleoside, 6-Modified purine nucleoside, 3'-Modified nucleoside. | |||
TNU0754 |
Purine-9-beta-D-(3’,5’-di-O-benzoyl-2’-deoxy-2’-fluoro)arabinoriboside
|
Others | Others |
Fluoro-modified nucleoside; 6-De-aminopurine nucleoside; Arabino-nculeoside | |||
TNU1426 |
3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside
|
Others | Others |
3,5-O-Ditoluoyl 6-chloropurine-9-β-D-deoxyriboside is a Nucleoside Derivative - Other modified nucleoside. | |||
TNU0083 |
2,6-Diaminopurine -9-beta-D-(2’-deoxy-2’-fluoro)-arabinoriboside
|
Others | Others |
Fluoro-modified nucleoside; arabino-nucleoside | |||
T124918 |
Nerbobscurine
|
Others | Others |
Nerbobscurine 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124918,CAS号为 38734-63-3。 | |||
T65626 |
8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione
|
Others | Others |
8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65626,CAS号为 93703-24-3。 | |||
T125916 |
Cassipourine
|
Others | Others |
Cassipourine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125916。 | |||
TNU0992 |
9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-6-chloropurine
|
Others | Others |
9-(5(R)-C-Methyl-2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-6-chloropurine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 TNU0992。 | |||
TNU1436 |
(S)-9-(2,3-Dihydroxypropyl)-2-amino-6-chloropurine
|
Others | Others |
(S)-9-(2,3-Dihydroxypropyl)-2-amino-6-chloropurine is a Nucleoside Derivative - Acyclic nucleoside. | |||
T84546 |
N-Stearoyl Taurine
|
Others | Others |
N-Arachidonoyl dopamine (NADA) and N-Arachidonoyl serine (ARA-S), among various arachidonoyl amino acids, have been extracted from bovine brain, while a novel series of fatty acyl amides of taurine were unearthed in rat brain through mass spectral lipidomic analysis, indicating the discovery of a new class of compounds also located in the kidney. These compounds are known to activate members of the transient receptor potential (TRP) family of calcium channels. Notably, N-Stearoyl taurine emerges... | |||
T79921 |
Moloney murine leukemia virus RT
|
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Moloney murine leukemia virus RT为源自Moloney小鼠白血病病毒的逆转录酶,作为复制聚合酶在逆转录病毒生命周期中扮演关键角色。 | |||
T83815 |
6-Chloropurine riboside-5'-triphosphate sodium
6-chloro PuTP |
Others | Others |
6-Chloropurine riboside-5'-triphosphate是一种RNA三磷酸酶mRNA-帽化酶β亚单位(Cet1; IC50 = 2 µM,针对S. cerevisiae酶的GTPase活性)的抑制剂,同时也是6-chloropurine riboside的磷酸化形式。此外,它还能激活E. coli天冬氨酸氨甲酰转移酶(EC50 = 0.76 mM)。6-Chloropurine riboside-5'-triphosphate已在合成具有抗癌活性的细胞因子以及一种光点击形式的ATP中得到应用。 | |||
TNU0772 |
6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purine
|
Others | Others |
6-Chloro-9-(2,3,5-tri-O-benzoyl-2-C-methyl-β-D-ribofuranosyl)-9H-purine is a 2'-C-Methyl nucleoside; Halo-nucleoside. | |||
T37277 |
2-Amino-6-chloropurine
|
Others | Others |
2-Amino-6-chloropurine is a precursor in the synthesis of nucleoside analogs with antiviral activity against Epstein-Barr virus (EBV) and human herpes virus 6 (HHV-6).1 1.Qiu, Y.-L., Ksebati, M.B., Ptak, R.G., et al.(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activityJ. Med. Chem.41(1)10-23(1998) | |||
TNU0669 |
6-Chloro-9-(tetrahydro-2-pyranyl)purine
|
Others | Others |
Intermediate and building block-electrophile, heterocyclic compound-purine | |||
TNU0017 |
6-(Furan-2-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside
|
Others | Others |
Nucleoside Derivatives - Fluoro-modified nucleosides; 6-Modified purine nucleosides, 3’-Modified nucleosides |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0613 |
3-Hydroxyisovaleric acid
β-羟基异戊酸,Beta-Hydroxyisovaleric acid |
Others; Endogenous Metabolite | Metabolism; Others |
3-Hydroxyisovaleric acid (Beta-Hydroxyisovaleric acid) 是尿液中排泄的内源性代谢产物 ,可作为生物素缺乏的早期和敏感指标。 | |||
T1688 |
Pregnanediol
5Beta-Pregnane-3Alpha,20alpha-Diol,孕甾二醇,Pregnandiol,孕二醇 |
Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) 是一种黄体酮的主要代谢物 (metabolite),能够通过尿液排出。它提供了一种间接测定体内孕激素水平的方法。 | |||
T5225 |
Hypotaurine
2-Aminoethanesulfinic acid,亚牛磺酸,2-Aminoethylsulfinic acid |
Chloride channel; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism |
Hypotaurine (2-Aminoethanesulfinic acid) 是星形胶质细胞中半胱氨酸生物合成的牛磺酸中间体,是甘氨酸受体 (glycine receptor) 的内源性抑制性氨基酸。Hypotaurine 也是抗氧化剂。 | |||
T0022 |
Taurine
牛磺酸,2-Aminoethanesulfonic acid |
LDL; Endogenous Metabolite; Autophagy | Autophagy; Metabolism |
Taurine (2-Aminoethanesulfonic acid) 是一种含硫氨基酸的有机渗透剂,为胆汁盐的形成提供底物,并在调节细胞内游离钙浓度方面发挥作用,有激活脂肪细胞自噬的能力。 | |||
T5766 |
(+)-Coclaurine
Coclaurine,乌药碱 |
Others | Others |
(+)-Coclaurine 是从多种植物来源中分离出来的四氢异喹啉生物碱,具有抗衰老作用。 | |||
T5S2102 |
Leonurine
益母草碱,盐酸益母草碱,SCM-198 |
Autophagy | Autophagy |
Leonurine (SCM-198) 是一种在益母草中发现的生物碱,具有抗氧化和抗炎作用。 | |||
T5581 |
6-(γ,γ-Dimethylallylamino)purine
N6-(2-lsopentenyl)adenine,三刺皂荚碱,Triacanthine |
Others | Others |
6-(γ,γ-Dimethylallylamino)purine (Triacanthine) 是植物生长调节剂。 | |||
T4746 |
Purine
7H-Imidazo(4,5-d)pyrimidine,嘌呤 |
Others; Endogenous Metabolite | Metabolism; Others |
Purine (7H-Imidazo(4,5-d)pyrimidine) 是内源性代谢产物的一种。 | |||
T1004 |
6-Benzylaminopurine
6-苄氨基嘌呤,6-BAP,N6-Benzyladenine,BA,Benzyladenine |
Others | Others |
6-Benzylaminopurine (6-BAP) 是一种细胞分裂素,能够通过刺激细胞分裂引起植物生长和发育,抑制呼吸激酶,从而延长绿色蔬菜的保鲜。 | |||
T4080 |
Leonurine hydrochloride
盐酸益母草碱,SCM-198 hydrochloride,SCM-198 HCl |
TLR; Autophagy | Autophagy; Immunology/Inflammation |
Leonurine hydrochloride (SCM-198 hydrochloride) 是从益母草中分离的一种生物碱,具有抗氧化和抗炎活性。 | |||
TN1519L |
(-)-Coclaurine hydrochloride
(-)-Coclaurine hydrochloride (486-39-5 Free base) |
AChR | Neuroscience |
(-)-Coclaurine hydrochloride 是从 Sarcopetalum harveyanum 中分离出来的,是一种 nAChR 拮抗剂。 | |||
T7444 |
6-(Dimethylamino)purine
N,N-Dimethyladenine,6-二甲基氨基嘌呤 |
Serine/threonin kinase; CDK | Cell Cycle/Checkpoint; Metabolism |
6-(Dimethylamino)purine (N,N-Dimethyladenine) 是一种丝氨酸苏氨酸蛋白激酶和 CDK 抑制剂。 | |||
T83588 |
(±)-Coclaurine
|
||
(±)-Coclaurine,Roemeria refracta 中的天然产物,具备抗氧化活性及对心血管系统的效应。 | |||
TN4613 |
(-)-N-methylcoclaurine
N-Methylcoclaurine |
Others | Others |
N-Methylcoclaurine shows binding affinities for the ĸ opioid receptor with the equilibrium dissociation constant (Ki) value of 0.9 ± 0.1 uM. N-methylcoclaurine also shows promising butyrylcholinesterase inhibition activities, with the IC50 value of 1 | |||
T78539 |
(+)-Coclaurine hydrochloride
d-Coclaurine hydrochloride,(R)-Coclaurine hydrochloride,(+)-(R)-Coclaurine hydrochloride |
Others | Others |
(+)-Coclaurine ((+)-(R)-Coclaurine) hydrochloride 是从多种植物中分离得到的四氢异喹啉类生物碱,具有抗衰老活性。 | |||
TN6370 |
Nudaurine
|
||
Nudaurine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6370,CAS号为 402469-62-9。 | |||
TN3696 |
Conodurine
|
AChR | Neuroscience |
Conodurine shows leishmanicidal and antibacterial activities, it shows inhibition activity for acetyl (AChE) and butyrylcholinesterase (BuChE). | |||
TN6369 |
Amurine
C09334 |
Antifungal | Microbiology/Virology |
Amurine (C09334) 是一种从P. stylatum分离出来的生物碱,具有潜在的抗菌活性。 | |||
TN1000 |
Solasurine
|
Others | Others |
Solasurine is a natural product with dissipate blood stasis and detumescence, relieve pain and pull poison. | |||
TN3387 |
Alpha-Obscurine
|
Others | Others |
Alpha-Obscurine是一种天然产物,属于石松科石松属,其产品编号为 TN3387,CAS号为 596-55-4。Alpha-Obscurine可用作对照参考。 | |||
TN1519 |
(S)-Coclaurine
衡州乌药碱, 乌药碱,Coclaurine |
AChR | Neuroscience |
(S)-Coclaurine (Coclaurine) 是一种从 Sarcopetalum harveyanum 中分离出来的,是一种 nAChR 拮抗剂。 | |||
TN1156 |
(-)-Curine
|
p53 | Apoptosis |
(-)-Curine can inhibit viability of hepatocellular carcinoma cells in regardless of p53 status. | |||
T80689 |
β-Obscurine
|
||
β-Obscurine为石松碱类生物碱,源自木麻黄石蒜(Lycopodium casuarinoides)。 | |||
TN6060 |
N-Demethyl-α-obscurine
|
||
N-Demethyl-alpha-obscurine is a natural product from Lycopodium japonicum. | |||
TN6101 |
Nandazurine
|
||
Nandazurine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6101,CAS号为 49679-20-1。 | |||
TN7379 |
N-Methyldehydrococlaurine
|
Others | Others |
T7508 |
N-Acetylputrescine hydrochloride
|
Endogenous Metabolite | Metabolism |
N-Acetylputrescine hydrochloride 是腐胺衍生物。 | |||
T5305 |
3-Methylbut-2-enoic acid
异戊烯酸,3,3-Dimethylacrylic Acid,Senecioic acid,3-Methylcrotonic Acid |
Others; Endogenous Metabolite | Metabolism; Others |
3-Methylbut-2-enoic acid (Senecioic acid) 是内源性代谢产物的一种。 | |||
T5550 |
2-Hydroxy-2-methylbutanoic acid
|
Others; Endogenous Metabolite | Metabolism; Others |
2-Hydroxy-2-methylbutanoic acid 是非正常的代谢物,与羟基戊二酸尿症以及枫糖尿病有关。 | |||
TN7118 |
Methylhippuric acid
Methyl hippurate,N-苯甲酰基甘氨酸甲酯 |
||
Methylhippuric acid (Methyl hippurate) 是人体尿液中二甲苯暴露的生物标志物。 | |||
T7464 |
3,3-Dimethylglutaric acid
3,3-二甲基戊二酸,3,3-Dimethylpentanedioate |
Others; Endogenous Metabolite | Metabolism; Others |
3,3-Dimethylglutaric acid (3,3-Dimethylpentanedioate) 是一种甲基支化脂肪酸,是一种人尿中偶见的内源性代谢物。 | |||
T0925 |
Allantoin
Glyoxyldiureide,尿囊素,5-Ureidohydantoin |
Endogenous Metabolite; Imidazoline Receptor | Metabolism; Neuroscience |
Allantoin (Glyoxyldiureide) 是一种存在于尿液和植物中的尿素乙内酰脲,用于皮肤病制剂。 | |||
T13482 |
2'-O-Methyladenosine
|
Endogenous Metabolite | Metabolism |
2'-O-Methyladenosine 是甲基化腺嘌呤的残基,在正常人群和腺苷脱氨基酶缺乏病人的尿液中均可被检测到。它显示出独特的降血压活性。 | |||
T4815 |
Hippuric acid
马尿酸,2-Benzamidoacetic acid,Benzoylglycine |
Others; Endogenous Metabolite | Metabolism; Others |
Hippuric acid (2-Benzamidoacetic acid) 是一种正常的尿液成分,是苯酸和甘氨酸结合作用下产生的一种酰基甘氨酸,来自食物的芳香化合物的代谢。 | |||
T5309 |
Dimethylamine hydrochloride
N,N-Dimethylamine,二甲胺盐酸盐 |
Others | Others |
Dimethylamine hydrochloride (N,N-Dimethylamine) 大量存在于人类尿液中。 | |||
T4856 |
Acetyl-L-lysine
N-乙酰-L-赖氨酸,Nα-Acetyl-L-lysine,(2S)-2-Acetamido-6-aminohexanoic acid |
Endogenous Metabolite | Metabolism |
Acetyl-L-lysine (Nα-Acetyl-L-lysine) 是一种 N-乙酰化氨基酸。它是人类尿液中的一种正常成分,在正常样本中的浓度太小,无法进行常规检测;然而,在一名氨基酰化酶I缺乏症患者的尿液中发现其水平升高。 | |||
T5251 |
Phenylpyruvic acid
2-Oxo-3-phenylpropanoic acid,3-Phenylpyruvic acid,苯丙酮酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Phenylpyruvic acid (3-Phenylpyruvic acid) 可以通过乳酸脱氢酶合成3-苯基乳酸 (PLA)。 | |||
T5277 |
3-Furanoic acid
3-Furoic acid,3-糠酸,3-Carboxyfuran,3-Furancarboxylic acid |
Others; Endogenous Metabolite | Metabolism; Others |
3-Furanoic acid (3-Carboxyfuran) 是内源性代谢产物的一种。 | |||
T4945 |
Normetanephrine hydrochloride
DL-Normetanephrine hydrochloride,DL-去甲变肾上腺素盐酸盐 |
Endogenous Metabolite | Metabolism |
Normetanephrine hydrochloride (DL-Normetanephrine hydrochloride) 是肾上腺素的代谢物。它与肾上腺素一起存在于尿液和某些组织中。 | |||
T5261 |
(E)-Oct-2-enoic acid
trans-2-Octenoic acid,2-Octenoate,2-辛烯酸,2-Octenoic acid |
Others; Endogenous Metabolite | Metabolism; Others |
(E)-Oct-2-enoic acid (2-Octenoate) 是内源性代谢产物的一种。 | |||
T4744 |
5-HYDROXYINDOLE-3-ACETIC ACID
5-羟基吲哚-3-乙酸,5-HIAA |
Others; Endogenous Metabolite | Metabolism; Others |
5-Hydroxyindole-3-acetic acid (5-HIAA) 是 甲氧基肾上腺素或5-羟色胺的主要代谢产物,被用作神经内分泌肿瘤的生物标志物。它是血清素的分解产物,能够从尿液中排出。 | |||
T5298 |
4-hydroxy-3-methylbenzoic acid
4-羟基-3-甲基苯甲酸,4,3-Cresotic acid |
Others; Endogenous Metabolite | Metabolism; Others |
4-hydroxy-3-methylbenzoic acid (4,3-Cresotic acid) 是一种来自健康人群的尿样中鉴定的正常有机酸。 | |||
T10388 |
Asparagusic acid
1,2-二噻戊环-4-羧酸,芦笋酸 |
Parasite | Microbiology/Virology |
Asparagusic acid 是芦笋植物中的一种含硫气味成分,是植物生长抑制剂,具有抗寄生虫作用。 | |||
T13616 |
cis-9,10-Epoxystearic acid
cis-9,10-Epoxystearic acid,cis-9,10-Epoxyoctadecanoic acid |
Endogenous Metabolite | Metabolism |
cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) 是来自人血液和尿液的内源性成分。它可以通过油酸和非酶环氧化反应从油酸中制备。 | |||
T4831 |
α,α-Dimethylglycine
2-Aminoisobutyric acid,α-Aminoisobutanoic acid,2-甲基丙氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
NSC-16590 (2-Aminoisobutyric acid) 对苍耳子叶中内源性乙烯(ethylene)的产生具有抑制作用。 | |||
T7523 |
Guanidinosuccinic acid
2-胍基琥珀酸,胍基琥珀酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Guanidinosuccinic acid 是一种含氮代谢物,在尿毒症患者的血清和尿液中水平升高。 | |||
T37177 |
Norcholic Acid
|
Others | Others |
Norcholic acid is a bile acid and 23-carbon derivative of cholic acid .1Levels of norcholic acid are increased in the urine of patients with liver cirrhosis or cerebrotendinous xanthomatosis (CTX), an inborn error of metabolism characterized by a deficiency in the mitochondrial enzyme sterol 27-hydrolylase (CYP27A1) that leads to progressive neurological symptoms.2,3,4 | |||
T39836 |
Monoethyl phthalate
|
Drug Metabolite | Metabolism |
Monoethyl phthalate 是邻苯二甲酸二乙酯在尿液中的主要代谢产物,是检测甲状腺癌和良性结节的潜在指标。 | |||
T5272 |
3-(3-Methoxyphenyl)propionic acid
3-(3-甲氧基苯基)丙酸,3-Methoxyhydrocinnamic acid |
Others; Endogenous Metabolite | Metabolism; Others |
3-(3-Methoxyphenyl)propionic acid (3-Methoxyhydrocinnamic acid) 是人体自然代谢的有机酸,排泄于尿液中。 | |||
T4825 |
D-(+)-Xylose
D(+)-Xylose,木糖,(+)-Xylose,Wood sugar |
Endogenous Metabolite | Metabolism |
D-(+)-Xylose (Wood sugar) 是一种是一种戊醛糖,其化学式为C5H10O5,甜度为蔗糖的40%。木糖也存在于结缔组织的粘多糖中,有时也存在于尿液中。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00952 |
Aquaporin-1/AQP1 Protein, Human, Recombinant (His & SUMO)
AQP1,AQP-1,Urine water channel,Aquaporin-1,Aquapori... |
Human | E. coli |
Aquaporin-1/AQP1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPJ-00135 |
BDNF Protein, Human/Murine/Rat, Recombinant
BDNF,Abrineurin,Brain-Derived Neurotrophic Factor |
Human,Mouse,Rat | E. coli |
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. ... | |||
TMPH-02465 |
Moloney murine leukemia virus (MoMLV) (isolate Shinnick) Gag polyprotein (GST)
gag,Gag polyprotein,Core polyprotein |
MoMLV | E. coli |
Moloney murine leukemia virus (MoMLV) (isolate Shinnick) Gag polyprotein (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 57.6 kDa and the accession number is P03332. | |||
TMPH-02985 |
Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (E. coli, His)
Major structural protein VP1,Major capsid protein VP1 |
MPyV | E. coli |
Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (E. coli, His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 42.4 kDa and the accession number is P24595. | |||
TMPH-02986 |
Murine polyomavirus (MPyV) (strain Kilham) VP2 Protein (His)
Minor capsid protein VP2,Minor structural protein VP2 |
MPyV | E. coli |
Murine polyomavirus (MPyV) (strain Kilham) VP2 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.4 kDa and the accession number is P24596. | |||
TMPH-02984 |
Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (His)
Major structural protein VP1,Major capsid protein VP1 |
MPyV | Baculovirus Insect Cells |
Murine polyomavirus (MPyV) (strain Kilham) VP1 Protein (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 42.5 kDa and the accession number is P24595. | |||
TMPY-00828 |
Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)
MPS2,IDS,SIDS,iduronate 2-sulfatase |
Human | HEK293 Cells |
Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfatase/IDS consists of a signal peptide, a propeptide, and a mature chain that may be further processed into two chains. Among the identified 18 human sulfatases, Iduronate 2-Sulfatase/IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG), heparan sulfate, an... | |||
TMPH-02777 |
Mup6 Protein, Mouse, Recombinant (His & SUMO)
Major urinary protein 6,Mup6,Alpha-2U-globulin,Group 1, BS6 |
Mouse | E. coli |
Binds pheromones that are released from drying urine of males. These pheromones affect the sexual behavior of females. Mup6 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.6 kDa and the accession number is P02762. | |||
TMPJ-00234 |
AMBP Protein, Human, Recombinant (His)
α-1-Microglobulin,Uronic-Acid-Rich Protein,Inter-α-Trypsin I... |
Human | HEK293 Cells |
Protein AMBP belongs to the calycin superfamily and Lipocalin family. AMBP can be cleaved into three chains: α-1-microglobulin, inter-α-trypsin inhibitor light chain and trypstatin. AMBP is expressed by the liver and secreted in plasma. α-1-microglobulin occurs in many physiological fluids including the plasma, urine, and cerebrospinal fluid. Inter-α-trypsin inhibitor is present in the plasma and urine. α-1-microglobulin occurs as a monomer and also in complexes with IgA and albumin, Inter-α-try... | |||
TMPJ-00876 |
FAH Protein, Human, Recombinant (His)
Fumarylacetoacetate Hydrolase,β-Diketonase,FAH,FAA,Fumarylac... |
Human | HEK293 Cells |
Fumarylacetoacetase belongs to the FAH family. Fumarylacetoacetase is primary expressed in liver and kidney. It exists as a homodimer and catalyzes the hydrolysis of 4-fumarylacetoacetate into fumarate and acetoacetate. Defects in Fumarylacetoacetase cause tyrosinemia type 1, which is congenital metabolism defect characterized by elevated levels of tyrosine in the blood and urine, and hepatorenal manifestations. Typical features include renal tubular injury, self-mutilation, hepatic necrosis, ep... | |||
TMPJ-01043 |
PHS Protein, Human, Recombinant (His)
4-Alpha-Hydroxy-Tetrahydropterin Dehydratase,Pterin-4-α-Carb... |
Human | E. coli |
Pterin-4-α-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4-α-Carbinolamine Dehydratase Family. PCBD1 is involved in Tetrahydrobiopterin biosynthesis. It seems to prevent the formation of 7-Pterins and accelerate the formation of Quinonoid-BH2. Furthermore, PCBD1 regulates the homodimerization of the transcription factor Hepatocyte Nuclear Factor 1 (HNF1) and enhances its transcriptional activity. Defects in PCBD1 are the cause of BH4-Deficient Hyperphenylalaninemia Type ... | |||
TMPH-02832 |
Serpin A5 Protein, Mouse, Recombinant (His)
Protein C inhibitor,Plasminogen activator inhibitor 3,Serpin... |
Mouse | Baculovirus Insect Cells |
Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin comple... | |||
TMPJ-00759 |
VDB Protein, Human, Recombinant (His)
Group-Specific Component,DBP,VDB,GC,Gc-Globulin,Vitamin D-Bi... |
Human | HEK293 Cells |
Vitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. DBP acts as a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. DBP binds to vitamin D and its plasma metabolites and transports them to target tissues. DBP associates with membrane-bound immunoglobulin on... | |||
TMPY-03658 |
ETHE1 Protein, Human, Recombinant (His)
YF13H12,HSCO,ethylmalonic encephalopathy 1 |
Human | E. coli |
ETHE1, also known as HSCO, is a sulfur dioxygenase that localizes within the mitochondrial matrix. ETHE1 probably plays an important role in metabolic homeostasis in mitochondria. It may also function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytoplasm. ETHE1 can suppresses p53-induced apoptosis by preventing nuclear localization of RELA. Mutations in ETHE1 gene result in ethylmalonic encephalopathy. Ethylmalonic en... | |||
TMPJ-01089 |
TFF1 Protein, Mouse, Recombinant (His)
Bcei,Protein pS2,Ps2,Trefoil factor 1,Tff1 |
Mouse | HEK293 Cells |
Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing.It originates from musculus and highly expressed by goblet cells of the gastric and intestinal mucosa and by conjunctival goblet cells. TFF1 is a copper-binding protein that can form disulfide-linked homodimers, associate into disulfide-linked complexes with Gastrokine 2, and fo... | |||
TMPY-02070 |
Cystatin SN Protein, Human, Recombinant (His)
CST1,cystatin SN |
Human | HEK293 Cells |
Cystatin-SN, also known as Cystain-SA-I, Cystatin-1, Salivary cystatin-SA-1 and CST1, is a secreted protein which belongs to thecystatin family. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. Cystatin-SN / CST1 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Cy... | |||
TMPJ-01351 |
XPNPEP1 Protein, Human, Recombinant (His)
Xaa-Pro Aminopeptidase 1,X-Prolyl Aminopeptidase 1 Soluble,A... |
Human | E. coli |
X-Prolyl Aminopeptidase (XPNPEP1) is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Because of its specificity toward proline, it has been suggested that X-Prolyl Aminopeptidase is important in the maturation and degradation of peptide hormones, neuropeptides, and tachykinins, as well as in the digestion of otherwise resistant dietary protein fragments, thereby compleme... | |||
TMPY-01644 |
Cystatin S Protein, Human, Recombinant (His)
MGC71923,cystatin S,CST4 |
Human | HEK293 Cells |
Cystatin-S, also known as Cystatin-4, Salivary acidic protein 1, Cystatin-SA-III and CST4, is a secreted protein which belongs to thecystatin family. Cystatin-4 / CST4 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). It is also expressed in saliva, tears, urine and seminal fluid. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while oth... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TMID-0167 |
6-Hydroxypurine-d4
|
||
6-Hydroxypurine-d4 是 6-Hydroxypurine 的氘代化合物。6-Hydroxypurine 的 CAS 号为 68-94-0。Hypoxanthine,也被称为 purine-6-ol 或 Hyp,属于嘌呤类有机化合物。Hypoxanthine 是一种天然存在的嘌呤衍生物,是腺苷代谢和核苷酸补救途径形成核酸的反应中间体。在正常情况下,Hypoxanthine 很容易转化为尿酸。Hypoxanthine 首先被氧化为黄嘌呤,黄嘌呤再被黄嘌呤氧化酶氧化为尿酸。 | |||
TMID-0170 |
Homotaurine-d6
|
||
Homotaurine-d6 是 Homotaurine 的氘代化合物。Homotaurine 的 CAS 号为 3687-18-1。Homotaurine 是一种具有口服活性的、可透过血脑屏障的天然氨基酸,存在于各种红色海藻中,能够可溶性 Aβ 结合并以非原纤维形式维持 Aβ。它是一种 GABA 类似物,具有神经保护,抗惊厥和抗高血压的活性。 | |||
TMID-0169 |
Taurine-d4
|
||
Taurine-d4 是 Taurine 的氘代化合物。Taurine 的 CAS 号为 107-35-7。Taurine 是一种含硫氨基酸的有机渗透剂,为胆汁盐的形成提供底物,并在调节细胞内游离钙浓度方面发挥作用,有激活脂肪细胞自噬的能力。 | |||
TMID-0160 |
5-Hydroxyindole-3-acetic Acid-d6
|
||
5-Hydroxyindole-3-acetic Acid-d6 是 5-Hydroxyindole-3-acetic Acid 的氘代化合物。5-Hydroxyindole-3-acetic Acid 的 CAS 号为 54-16-0。5-Hydroxyindole-3-acetic acid 是 甲氧基肾上腺素或5-羟色胺的主要代谢产物,被用作神经内分泌肿瘤的生物标志物。它是血清素的分解产物,能够从尿液中排出。 | |||
TMIJ-0297 |
Acetylsulfamethoxazole-d4
|
||
Acetylsulfamethoxazole-d4 是 Acetylsulfamethoxazole 的氘代化合物。Acetylsulfamethoxazole 的 CAS 号为 21312-10-7。N4-Acetylsulfamethoxazole 是磺胺甲恶唑的一种代谢物。Sulfamethoxazole 属于磺胺类抗菌素,可用于细菌感染。 | |||
TMIJ-0041 |
Hippuric Acid-d5
|
||
Hippuric Acid-d5 是 Hippuric Acid 的氘代化合物。Hippuric Acid 的 CAS 号为 495-69-2。Hippuric Acid 是一种正常的尿液成分,是苯酸和甘氨酸结合作用下产生的一种酰基甘氨酸,来自食物的芳香化合物的代谢。 | |||
TMIJ-0142 |
Vildagliptin-d7
|
||
Vildagliptin-d7 是 Vildagliptin 的氘代化合物。Vildagliptin 的 CAS 号为 274901-16-5。Vildagliptin 是一种选择性二肽基肽酶IV (DPP-IV) 抑制剂,在人 Caco-2 细胞中抑制 DPP-IV 的IC50为 3.5 nM。它具有出色的口服生物利用度和降血糖活性。 | |||
TMID-0097 |
Ethyl-d5-malonic Acid
|
||
Ethyl-d5-malonic Acid 是 Ethyl-malonic Acid 的氘代化合物。Ethyl-malonic Acid 的 CAS 号为 601-75-2。Ethylmalonic acid 是潜在有毒物质,非致癌性,与神经性厌食和甲氧基脱羧酶缺乏症有关。 | |||
T36537 |
Nitrofurantoin-13C3
Nitrofurantoin-13C3 |
||
Nitrofurantoin-13C3is intended for use as an internal standard for the quantification of nitrofurantoin by GC- or LC-MS. Nitrofurantoin is a nitrofuran antibiotic.1In vivo, nitrofurantoin (25-100 mg/kg) reducesE. colireplication and abscess formation in the renal medulla of infected rats in a dose-dependent manner. It prevents kidney and bladder infection in rats following bladder inoculation with clinical isolates ofP. mirabilis. Nitrofurantoin also prevents alkalization of urine, as well as ca... | |||
TMID-0096 |
P-CRESOL-d3 (METHYL-d3)
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P-CRESOL-d3 (METHYL-d3) 是 P-CRESOL 的氘代化合物。P-CRESOL 的 CAS 号为 106-44-5。p-Cresol 是一种部分亲脂性部分,在正常条件下与血浆蛋白(接近 100%)强烈结合。对甲酚通过结合代谢,主要是硫酸化和葡萄糖醛酸化,但未结合的对甲酚至少部分通过尿液去除。 |