47
2
29
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16949 |
Sucrose octaacetate
|
Others | Others |
Sucrose octaacetate 是蔗糖的乙酰化衍生物,具有强烈的苦味,可用作苦味替代品。它可用作食品添加剂,还可用作粘合剂和增塑剂。它也可用作软模板,以合成聚苯胺纳米纤维。它还用于许多农药,杀虫剂和其他有毒产品中,以防止意外中毒。 | |||
T5286 |
Glycylglycine
Glycyl-glycine,Glycine dipeptide,Diglycocoll,Diglycine,Gly-gly,双甘肽,N-Glycylglycine |
Others; Endogenous Metabolite | Metabolism; Others |
Glycylglycine (Diglycine) 是一种简单的多肽,能够作为谷氨酰胺 (gamma-glutamyl) 的受体。 | |||
T16703 |
Quarfloxin
CX-3543 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Quarfloxin (CX-3543) 是一种氟喹诺酮衍生物,具有抗肿瘤活性,可靶向抑制RNA pol I 的活性,在神经母细胞瘤细胞中的 IC50 值在纳摩尔范围内。它破坏核糖体 DNA 模板中核仁蛋白和 G-四链体 DNA 结构之间的相互作用。 | |||
TNU1075 |
2-Iodo-2’-deoxyadenosine
|
Others | Others |
2-Iodo-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside; 2-Modified purine nucleoside; Scaffold and Template. | |||
TNU1278 |
2,6-Dichloro-2',3',5'-triacetyl-purine riboside
|
Others | Others |
2,6-Dichloro-2',3',5'-triacetyl-purine riboside is a Nucleoside Derivative - Halo-nucleoside; Scaffold and Template. | |||
TNU0275 |
8-Aza-7-bromo-7-deazaguanosine
|
Others | Others |
8-Aza-7-bromo-7-deazaguanosine is a Nucleoside Derivative - 7-Deaza-8-aza-purine nucleoside; Halo-nucleoside; Scaffold and Template. | |||
TNU1013 |
6-Chloro-7-fluoro-7-deazapurine
|
Others | Others |
6-Chloro-7-fluoro-7-deazapurine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template. | |||
TNU0879 |
6-Chloro-2-iodo-9-(2,3,5-tri-O-acetyl)-beta-D-ribofuranosyl-9H-purine
|
Others | Others |
6-Chloro-2-iodo-9-(2,3,5-tri-O-acetyl)-beta-D-ribofuranosyl-9H-purine is a Nucleoside Derivative - Halo-nucleoside; Scaffold and Template. | |||
TNU1016 |
6-Bromopyrazolo[3,4-d]pyrimidin-4(5H)-one
|
Others | Others |
6-Bromopyrazolo[3,4-d]pyrimidin-4(5H)-one bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template. | |||
TNU1015 |
4-Amino-6-bromo-5-cyano-7H-pyrrolo[2,3-d]pyrimidine
|
Others | Others |
4-Amino-6-bromo-5-cyano-7H-pyrrolo[2,3-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template. | |||
TNU0870 |
5-(2-Hydroxyethyl)uracil
|
Others | Others |
5-(2-Hydroxyethyl)uracil bolongs toIntermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocylic Compounds - Pyrimidine; Scaffold and Template. | |||
TNU0877 |
N-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl propanamide
|
Others | Others |
N-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl propanamide belongs to Heterocyclic Compounds - Purine; Intermediates and Building Blocks - Nucleoside base, Electrophile; Scaffold and Template. | |||
TNU0121 |
5-Pyrrolidinomethyluridine
|
Others | Others |
5-Pyrrolidinomethyluridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Scaffold and Template. | |||
TNU0872 |
5-(3-Hydroxypropyl)uracil
|
Others | Others |
5-(3-Hydroxypropyl)uracil bolongs toIntermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocylic Compounds - Pyrimidine; Scaffold and Template. | |||
TNU0760 |
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine
|
Others | Others |
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine is a Nucleoside Derivative - Fluoro-modified nucleoside, 6-Modified purine nucleoside, Halo-nucleoside, 3'-Modified nucleoside; Scaffold and Template. | |||
TNU1018 |
6-Amino-4-chloropyrazolo[3,4-d]pyrimidine
|
Others | Others |
6-Amino-4-chloropyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template. | |||
TNU0871 |
5-(2-Hydroxyethyl)-2-thiouracil
|
Others | Others |
5-(2-Hydroxyethyl)-2-thiouracil bolongs toIntermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocylic Compounds - Pyrimidine; Scaffold and Template. | |||
TNU1068 |
4-Chloro-7-[(5-O-t-butyldimethylsilyl)-2,3-O-isopropyli-dene-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine
|
Others | Others |
Nucleoside Derivatives - 7-Deaza-purine nucleoside; Halo-nucleoside; Scaffolds and Template | |||
TNU1017 |
3,6-Dibromopyrazolo[3,4-d]pyrimidin-4(5H)-one
|
Others | Others |
3,6-Dibromopyrazolo[3,4-d]pyrimidin-4(5H)-one bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template. | |||
TNU1279 |
5-(2-Hyroxyethyl)-2’,3’-di-O-toluoyl-2’-deoxyuridine
|
Others | Others |
5-(2-Hyroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Scaffold and Template. | |||
TNU1074 |
2-Bromo-2’-deoxyadenosine
|
Others | Others |
2-Bromo-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside; 2-Modified purine nucleoside; Scaffold and Template. | |||
TNU1019 |
6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine
|
Others | Others |
6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template. | |||
TNU1020 |
6-Amino-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine
|
Others | Others |
6-Amino-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template. | |||
TNU1069 |
4-Chloro-7-(2,3-O-isopropylidene-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
|
Others | Others |
Nucleoside Derivatives - 7-Deaza-purine nucleoside; Halo-nucleoside, Protected nucleosides with NH2/OH open; Scaffolds and Template | |||
TNU0632 |
5’-O-(p-Toluoyl)-2’-O-acetyl-3’-deoxy-3’-fluoro-6-chloroinosine
|
Others | Others |
5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluoro-6-chloroinosine is a Nucleoside Derivative - Fluoro-modified nucleoside, Halo-nucleoside, 3'-Modified nucleoside; Scaffold and Template. | |||
TNU1073 |
6-Chloro-2-bromo-9-(2,3,5-tri-O-acetyl)-beta-D-ribofuranosyl-9H-purine
|
Others | Others |
6-Chloro-2-bromo-9-(2,3,5-tri-O-acetyl)-beta-D-ribofuranosyl-9H-purine is a Nucleoside Derivative - Halo-nucleoside; Scaffold and Template. | |||
TNU1034 |
4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine
|
Others | Others |
4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside, 8-Modified-purine nucleoside, Halo-nucleoside; Scaffold and Template. | |||
TNU0090 |
2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine
|
Others | Others |
2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine is a Nucleoside Derivative - Fluoro-modified nucleoside, Halo-nucleoside, 3'-Modified nucleoside; Scaffold and Template. | |||
TNU0983 |
2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine
|
Others | Others |
2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine is a Nucleoside Derivative - 3'-Deoxy nucleoside, Halo-nucleoside; Scaffold and Template. | |||
TNU0981 |
9-(2’-O-Acetyl-5’-O-benzoyl-3’-deoxy-beta-D-ribofuranosyl)-6-chloropurine
|
Others | Others |
9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is a Nucleoside Derivative - 3'-Deoxy nucleoside, Halo-nucleoside; Scaffold and Template. | |||
TNU0103 |
4-Amino-5-iodo-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
|
Others | Others |
4-Amino-5-iodo-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside; Halo-nucleoside; Scaffold and Template. | |||
TNU0102 |
4-Chloro-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine
|
Others | Others |
4-Chloro-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside; Halo-nucleoside; Scaffold and Template. | |||
TNU0088 |
2-Chloro-6-(furan-2-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside
|
Others | Others |
2-Chloro-6-(furan-2-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside is a Nucleoside Derivative - Fluoro-modified nucleoside, 6-Modified purine nucleoside, Halo-nucleoside, 3'-Modified nucleoside; Scaffold and Template. | |||
T25287 |
Dansyllysine
Dns-lysine |
Others | Others |
Dansyllysine is utilized to study binding conformations of drugs to human serum albumin and is utilized as a template molecule to form molecularly imprinted monolayers (MIMs) useful to produce optical biosensor recognition elements. | |||
TNU0982 |
2-Amino-6-chloro-9-(3-deoxy-2-O-acetyl-5-O-benzoyl-beta-D-ribofuanosyl)-9H-purine
|
Others | Others |
2-Amino-6-chloro-9-(3-deoxy-2-O-acetyl-5-O-benzoyl-beta-D-ribofuanosyl)-9H-purine is a Nucleoside Derivative - 3'-Deoxy nucleoside, Halo-nucleoside; Scaffold and Template. | |||
TNU0878 |
N-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl propanamide
|
Others | Others |
N-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl propanamide belongs to Heterocyclic Compounds - Purine; Intermediates and Building Blocks - Nucleoside base, Electrophile; Scaffold and Template. | |||
TNU1035 |
3,6-Dibromo-1,5-dihydro-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one
|
Others | Others |
3,6-Dibromo-1,5-dihydro-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one is a Nucleoside Derivative - 7-Deaza-8-aza-purine nucleoside; Halo-nucleoside; Scaffold and Template. | |||
TNU1033 |
4-Amino-6-bromo-5-cyano-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine
|
Others | Others |
4-Amino-6-bromo-5-cyano-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside, 8-Modified-purine nucleoside, Halo-nucleoside; Scaffold and Template. | |||
T24919 |
UBP714
UBP 714,UBP-714 |
Others | Others |
UBP714 is a derivative of the NMDA receptor negative allosteric modulator UBP608. It also enhanced NMDAR mediated field EPSPs in the CA1 region of the hippocampus. UBP714 is a novel template for the development of potent and subunit selective NMDAR potent | |||
T78736 |
D3R ligand 1
|
Dopamine Receptor | GPCR/G Protein; Neuroscience |
D3R ligand 1 (compound 23b) 是针对多巴胺受体D3R具有高效选择性的配体,拥有66 nM的Ki值,且包含THPB模板。此外,D3R ligand 1 同时作为基于G蛋白及β-arrestin信号传导路径的拮抗剂。 | |||
T61886 |
HBV-IN-16
|
Others | Others |
HBV-IN-16 是一种有效的共价闭合环状 DNA (cccDNA) 抑制剂。cccDNA 作为病毒 RNA 转录和随后病毒 DNA 生成的模板。HBV-IN-16 是一种喹啉衍生物。HBV-IN-16 具有研究 HBV 感染的潜力 。 | |||
T81422 |
Pomalidomid-C6-PEG3-butyl-N3
|
PROTACs | PROTAC |
Pomalidomid-C6-PEG3-butyl-N3为具有叠氮基的点击化学试剂,同时作为交联剂-E3连接酶配体偶联物,它在PROTAC领域用于点击反应蛋白降解剂构建块,以及靶向蛋白降解剂合成的模板。 | |||
T82916 |
BChE-IN-20
|
Others | Others |
BChE-IN-20(compound 7c)作为一种BChE选择性抑制剂显示出高效性,其对eqBChE的IC50为105 nM,对hBChE的IC50为2.3 nM。同时,BChE-IN-20对P糖蛋白的IC50值为0.27 μM。此化合物为BChE选择性配体的设计与开发,包括抑制剂与荧光探针,提供了一个有潜力的模板。 | |||
T83123 |
Amyloid β-Protein (3-42)
|
||
Amyloid β-Protein (3-42) 为Pyr肽前体, 其焦谷氨酸修饰的形式 Aβ (pEAβ) (3-42) 构成阿尔茨海默病淀粉样斑块的关键。pEAβ (3-42) 能促进 Aβ(1-42) 聚集,并且 Aβ(1-42) 显著延缓pEAβ(3-42) 的初级及次级成核过程。 | |||
T35693 |
N-(2-Azidoethyl)betulonamide
|
Others | Others |
N-(2-Azidoethyl)betulonamide is a pentacyclic triterpenoid, a derivative of betulonic acid , and an intermediate in the synthesis of betulonic acid derivatives within vitrocancer cell cytotoxicity.1 1.Suman, P., Patel, A., Solano, L., et al.Synthesis and cytotoxicity of Baylis-Hillman template derived betulinic acid-triazole conjugatesTetrahedron73(29)4214-4226(2017) | |||
T35658 |
3'-Deoxyuridine-5'-triphosphate trisodium
|
Others | Others |
3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1]. 3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is synthesized starting from cordycepin in good yield. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA by the RNA polym... | |||
T35657 |
3'-Deoxyuridine-5'-triphosphate
|
Others | Others |
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1]. 3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is synthesized starting from cordycepin in good yield. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA by the RNA polymerases. 3'-Deoxyuridine-5'-tri... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TJS0311 |
Ethyl 3-coumarincarboxylate
3-Ethoxycarbonylcoumarin,香豆素-3-羧酸乙酯,香豆素-3-羧酸乙素,Ethyl 2-Oxo-2H-Chromene-3-Carboxylate,Ethyl coumarin-3-carboxylate,3-Carbethoxycoumarin |
Others | Others |
Ethyl coumarin-3-carboxylate 是香豆素衍生物。它可作为一种伪模板,制备能够特异性识别黄曲霉毒素的分子印迹聚合物 (MIP)。 | |||
T13592 |
Calf thymus DNA
DNA from calf thymus, Thymonucleic acid |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) 是一种从牛胸腺中提取出来的高质量双链模板DNA,可广泛应用于DNA 结合抗癌剂和调节DNA 结构和功能的DNA 结合剂的研究。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02543 |
PCNA Protein, Human, Recombinant (His)
ATLD2,proliferating cell nuclear antigen |
Human | Baculovirus Insect Cells |
Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. It is central to both DNA replication and repair. One of the well-established functions for PCNA is its role as the processivity factor for DNA polymerase delta and epsilon. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. Two forms of PCNA exist in cells: (i) a detergent-insoluble trimeric form stably associated with the replic... | |||
TMPH-01674 |
Human metapneumovirus (strain CAN97-83) Nucleoprotein/NP Protein (His & Myc)
Nucleoprotein,N,Nucleocapsid protein |
HMPV | E. coli |
Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases. RNA replication depends on the availability of soluble nucleoprotein. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. | |||
TMPH-03416 |
Rift valley fever virus (RVFV) (strain ZH-548 M12) Nucleoprotein/NP Protein (His & SUMO)
N,Nucleoprotein,Nucleocapsid protein |
RVFV | E. coli |
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles. Rift valley fever virus (RVFV) (strain ZH-548 M12) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.... | |||
TMPH-00360 |
DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant
Exodeoxyribonuclease large subunit,DNA polymerase II large s... |
Cenarchaeum symbiosum | E. coli |
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 59.0 kDa and the accession number is A0RYM0. | |||
TMPH-00316 |
Bunyavirus La Crosse Nucleoprotein/NP Protein (His)
Nucleoprotein,Protein N,Nucleocapsid protein,N |
Bunyavirus La Crosse | P. pastoris (Yeast) |
Encapsidates the genome protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication. Seems to participate in the nuclear relocalization of host PABP1, thereby inhibiting host cellular translation. Bunyavirus La Crosse Nucleoprotein/NP Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 28.5 kDa and the accession number is P04873. | |||
TMPH-03729 |
Zaire ebolavirus (strain Kikwit-95) VP30 Protein (His)
Transcriptional activator VP30,EbolaVP30,Minor nucleoprotein... |
ZEBOV | E. coli |
Multifunctional protein that acts as a viral transcriptional activator. Promotes read-through of an RNA hairpin in the NP open reading frame to enhance viral transcription. Mechanistically, nonphosphorylated VP30 hexamers form a ternary complex with the viral leader RNA. Clamps the RNA template and the complex VP35-polymerase L together, thereby increasing the polymerase affinity for the RNA template to increase transcription initiation despite the presence of RNA secondary structures. Assists a... | |||
TMPH-02711 |
H2B type 1-M Protein, Mouse, Recombinant (His)
Histone H2B type 1-M,H2bc14,H2B 291B |
Mouse | E. coli |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. HIST1H2BM Protein, Mouse, Recombinant (His) is expressed in E... | |||
TMPH-00741 |
Rho Protein, E. coli, Recombinant (His)
Transcription termination factor Rho,ATP-dependent helicase ... |
E. coli | E. coli |
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPase which utilizes all four ribonucleoside triphosphates as substrates. Rho Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 51.0 kDa and the accession number is P0AG30. | |||
TMPH-02186 |
TERT Protein, Human, Recombinant (His)
Telomerase reverse transcriptase,Telomerase catalytic subuni... |
Human | E. coli |
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-de... | |||
TMPH-03698 |
VSIV (strain Glasgow) Phosphoprotein Protein (His & Myc)
Phosphoprotein,P,Protein M1 |
VSIV | E. coli |
Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template. May act as a chaperone for newly synthesized free N protein, so-called N(0). Plays a role in virion assembly. VSIV (strain Glasgow) Phosphoprotein Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.9 kDa and the accession number is P04879. | |||
TMPH-01843 |
Human parainfluenza 4b virus (HPIV-4b) Nucleoprotein/NP Protein (His)
Nucleoprotein,Nucleocapsid protein,N |
HPIV-4b | E. coli |
Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. Human parainfluenza 4b virus (HPIV-4b) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 68.5 ... | |||
TMPH-01247 |
POLR3K Protein, Human, Recombinant (His)
RNA polymerase III subunit C11,POLR3K,RNA polymerase III 12.... |
Human | Baculovirus Insect Cells |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase I... | |||
TMPH-01246 |
POLR3A Protein, Human, Recombinant (His)
RNA polymerase III subunit C160,RNA polymerase III 155 kDa s... |
Human | E. coli |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft ... | |||
TMPH-03696 |
VSIV (strain San Juan) Nucleoprotein/NP Protein (His & Myc)
Nucleocapsid protein,N,Nucleoprotein |
VSIV | E. coli |
Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. Nucleocapsid assembly is concommitant with replication, therefore viral replication depends on the intracellular concentration of free N, termed N(0). All replicative products are resistant to nucleases. VSIV (strain San Juan) Nucleoprotein/NP Protein (His & Myc) is expressed in E. coli expressi... | |||
TMPH-02380 |
RPB5 Protein, Kluyveromyces marxianus, Recombinant (His)
RPB5,DNA-directed RNA polymerases I, II, and III subunit RPA... |
Kluyveromyces marxianus | E. coli |
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol... | |||
TMPH-01841 |
Human parainfluenza 1 virus (HPIV-1) Nucleoprotein/NP Protein (His)
Nucleoprotein,Nucleocapsid protein,N |
HPIV-1 | E. coli |
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. Human parainfluenza 1 virus (HPIV-1) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with N-10xHis tag. T... | |||
TMPH-00811 |
Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc)
Small delta antigen,p24 |
HDV | P. pastoris (Yeast) |
Promotes both transcription and replication of genomic RNA. Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. May interact with host RNA polymerase II thereby changing its template requirement from DNA to RNA. RNA pol II complex would then acts as an RNA-directed RNA polymerase, and transcribe and replicate HDV genome. Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc) is expressed in yeast with N-6xHi... | |||
TMPY-00323 |
Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)
NS3 |
HCV | E. coli |
HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B. HCV NS3 RNA helicase binds to RNA and unwinds dsRNA in the 3' to 5' direction, and likely RNA stable secondary structure in the template strand (By similarity). Cleaves and inhibits the host antiviral protein MAVS. NS3/NS4A complex also prevents phosphorylation of human IRF3, t... | |||
TMPH-02351 |
Influenza A H3N2 (strain A/Beijing/353/1989) Nucleoprotein/NP Protein (His & SUMO)
Nucleoprotein,NP,Nucleocapsid protein |
H3N2 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw... | |||
TMPH-02353 |
Influenza A H1N1 (strain A/Fort Warren/1/1950) Nucleoprotein/NP Protein (His & SUMO)
Nucleocapsid protein,Nucleoprotein,NP |
H1N1 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw... | |||
TMPH-02354 |
Influenza A H1N1 (strain A/New Jersey/8/1976) Nucleoprotein/NP Protein (His & SUMO)
NP,Nucleocapsid protein,Nucleoprotein |
H1N1 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw... | |||
TMPH-02355 |
Influenza A H3N2 (strain A/Port Chalmers/1/1973) Nucleoprotein/NP Protein (His & SUMO)
NP,Nucleoprotein,Nucleocapsid protein |
H3N2 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw... | |||
TMPH-02350 |
Influenza A H3N2 (strain A/Shanghai/16/1989) Nucleoprotein/NP Protein (His)
NP,Nucleocapsid protein,Nucleoprotein |
H3N2 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw... | |||
TMPY-01332 |
HIST1H3A Protein, Human, Mouse, Recombinant
Histone H3.1,histone cluster 1, H3a,Histone H3 |
Human,Mouse | E. coli |
Histone H3.1, also known as HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, is a member of the histone H3 family which is a core component of nucleosome. It is expressed during the S phase, then expression strongly decreases as cell division slows down during the process of differentiation. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machinery which requires DNA as a template. Histones thereby pla... | |||
TMPH-02352 |
Influenza A H3N2 (strain A/Kitakyushu/159/1993) Nucleoprotein/NP Protein (His)
Nucleocapsid protein,NP,Nucleoprotein |
H3N2 | E. coli |
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw... | |||
TMPH-01001 |
BCL10 Protein, Human, Recombinant (His & SUMO)
B-cell lymphoma/leukemia 10,cCARMEN,hCLAP,CIPER,CLAP,BCL10,B... |
Human | E. coli |
Plays a key role in both adaptive and innate immune signaling by bridging CARD domain-containing proteins to immune activation. Acts by channeling adaptive and innate immune signaling downstream of CARD domain-containing proteins CARD9, CARD11 and CARD14 to activate NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. Recruited by activated CARD domain-containing proteins: homooligome... | |||
TMPH-01238 |
POLQ Protein, Human, Recombinant (His)
DNA polymerase eta,POLQ,DNA polymerase theta |
Human | Baculovirus Insect Cells |
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions, some of them leading to cellular transformation. POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumul... | |||
TMPH-01288 |
Elongin-B Protein, Human, Recombinant (GST)
EloB,Elongin-B,TCEB2,ELOB,SIII p18 |
Human | E. coli |
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region ... | |||
TMPH-01237 |
POLQ Protein, Human, Recombinant (E. coli, His)
DNA polymerase eta,POLQ,DNA polymerase theta |
Human | E. coli |
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions, some of them leading to cellular transformation. POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumul... |