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Targets Recommended: Others

47

抑制剂 & 化合物

2

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29

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T16949 Sucrose octaacetate

Others Others
Sucrose octaacetate 是蔗糖的乙酰化衍生物,具有强烈的苦味,可用作苦味替代品。它可用作食品添加剂,还可用作粘合剂和增塑剂。它也可用作软模板,以合成聚苯胺纳米纤维。它还用于许多农药,杀虫剂和其他有毒产品中,以防止意外中毒。
T5286 Glycylglycine

Glycyl-glycine,Glycine dipeptide,Diglycocoll,Diglycine,Gly-gly,双甘肽,N-Glycylglycine

Others; Endogenous Metabolite Metabolism; Others
Glycylglycine (Diglycine) 是一种简单的多肽,能够作为谷氨酰胺 (gamma-glutamyl) 的受体。
T16703 Quarfloxin

CX-3543

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Quarfloxin (CX-3543) 是一种氟喹诺酮衍生物,具有抗肿瘤活性,可靶向抑制RNA pol I 的活性,在神经母细胞瘤细胞中的 IC50 值在纳摩尔范围内。它破坏核糖体 DNA 模板中核仁蛋白和 G-四链体 DNA 结构之间的相互作用。
TNU1075 2-Iodo-2’-deoxyadenosine

Others Others
2-Iodo-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside; 2-Modified purine nucleoside; Scaffold and Template.
TNU1278 2,6-Dichloro-2',3',5'-triacetyl-purine riboside

Others Others
2,6-Dichloro-2',3',5'-triacetyl-purine riboside is a Nucleoside Derivative - Halo-nucleoside; Scaffold and Template.
TNU0275 8-Aza-7-bromo-7-deazaguanosine

Others Others
8-Aza-7-bromo-7-deazaguanosine is a Nucleoside Derivative - 7-Deaza-8-aza-purine nucleoside; Halo-nucleoside; Scaffold and Template.
TNU1013 6-Chloro-7-fluoro-7-deazapurine

Others Others
6-Chloro-7-fluoro-7-deazapurine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU0879 6-Chloro-2-iodo-9-(2,3,5-tri-O-acetyl)-beta-D-ribofuranosyl-9H-purine

Others Others
6-Chloro-2-iodo-9-(2,3,5-tri-O-acetyl)-beta-D-ribofuranosyl-9H-purine is a Nucleoside Derivative - Halo-nucleoside; Scaffold and Template.
TNU1016 6-Bromopyrazolo[3,4-d]pyrimidin-4(5H)-one

Others Others
6-Bromopyrazolo[3,4-d]pyrimidin-4(5H)-one bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU1015 4-Amino-6-bromo-5-cyano-7H-pyrrolo[2,3-d]pyrimidine

Others Others
4-Amino-6-bromo-5-cyano-7H-pyrrolo[2,3-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU0870 5-(2-Hydroxyethyl)uracil

Others Others
5-(2-Hydroxyethyl)uracil bolongs toIntermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocylic Compounds - Pyrimidine; Scaffold and Template.
TNU0877 N-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl  propanamide

Others Others
N-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl propanamide belongs to Heterocyclic Compounds - Purine; Intermediates and Building Blocks - Nucleoside base, Electrophile; Scaffold and Template.
TNU0121 5-Pyrrolidinomethyluridine

Others Others
5-Pyrrolidinomethyluridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Scaffold and Template.
TNU0872 5-(3-Hydroxypropyl)uracil

Others Others
5-(3-Hydroxypropyl)uracil bolongs toIntermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocylic Compounds - Pyrimidine; Scaffold and Template.
TNU0760 9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine

Others Others
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine is a Nucleoside Derivative - Fluoro-modified nucleoside, 6-Modified purine nucleoside, Halo-nucleoside, 3'-Modified nucleoside; Scaffold and Template.
TNU1018 6-Amino-4-chloropyrazolo[3,4-d]pyrimidine

Others Others
6-Amino-4-chloropyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU0871 5-(2-Hydroxyethyl)-2-thiouracil

Others Others
5-(2-Hydroxyethyl)-2-thiouracil bolongs toIntermediates and Building Blocks - Nucleoside base, Nucleophile; Heterocylic Compounds - Pyrimidine; Scaffold and Template.
TNU1068 4-Chloro-7-[(5-O-t-butyldimethylsilyl)-2,3-O-isopropyli-dene-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine

Others Others
Nucleoside Derivatives - 7-Deaza-purine nucleoside; Halo-nucleoside; Scaffolds and Template
TNU1017 3,6-Dibromopyrazolo[3,4-d]pyrimidin-4(5H)-one

Others Others
3,6-Dibromopyrazolo[3,4-d]pyrimidin-4(5H)-one bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU1279 5-(2-Hyroxyethyl)-2’,3’-di-O-toluoyl-2’-deoxyuridine

Others Others
5-(2-Hyroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Scaffold and Template.
TNU1074 2-Bromo-2’-deoxyadenosine

Others Others
2-Bromo-2'-deoxyadenosine is a Nucleoside Derivative - Halo-nucleoside; 2-Modified purine nucleoside; Scaffold and Template.
TNU1019 6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine

Others Others
6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU1020 6-Amino-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine

Others Others
6-Amino-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU1069 4-Chloro-7-(2,3-O-isopropylidene-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

Others Others
Nucleoside Derivatives - 7-Deaza-purine nucleoside; Halo-nucleoside, Protected nucleosides with NH2/OH open; Scaffolds and Template
TNU0632 5’-O-(p-Toluoyl)-2’-O-acetyl-3’-deoxy-3’-fluoro-6-chloroinosine

Others Others
5'-O-(p-Toluoyl)-2'-O-acetyl-3'-deoxy-3'-fluoro-6-chloroinosine is a Nucleoside Derivative - Fluoro-modified nucleoside, Halo-nucleoside, 3'-Modified nucleoside; Scaffold and Template.
TNU1073 6-Chloro-2-bromo-9-(2,3,5-tri-O-acetyl)-beta-D-ribofuranosyl-9H-purine

Others Others
6-Chloro-2-bromo-9-(2,3,5-tri-O-acetyl)-beta-D-ribofuranosyl-9H-purine is a Nucleoside Derivative - Halo-nucleoside; Scaffold and Template.
TNU1034 4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine

Others Others
4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside, 8-Modified-purine nucleoside, Halo-nucleoside; Scaffold and Template.
TNU0090 2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine

Others Others
2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine is a Nucleoside Derivative - Fluoro-modified nucleoside, Halo-nucleoside, 3'-Modified nucleoside; Scaffold and Template.
TNU0983 2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine

Others Others
2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine is a Nucleoside Derivative - 3'-Deoxy nucleoside, Halo-nucleoside; Scaffold and Template.
TNU0981 9-(2’-O-Acetyl-5’-O-benzoyl-3’-deoxy-beta-D-ribofuranosyl)-6-chloropurine

Others Others
9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is a Nucleoside Derivative - 3'-Deoxy nucleoside, Halo-nucleoside; Scaffold and Template.
TNU0103 4-Amino-5-iodo-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

Others Others
4-Amino-5-iodo-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside; Halo-nucleoside; Scaffold and Template.
TNU0102 4-Chloro-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]   pyrimidine

Others Others
4-Chloro-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d] pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside; 2'-Modified nucleoside; Halo-nucleoside; Scaffold and Template.
TNU0088 2-Chloro-6-(furan-2-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside

Others Others
2-Chloro-6-(furan-2-yl)purine-beta-D-(3'-deoxy-3'-fluoro)riboside is a Nucleoside Derivative - Fluoro-modified nucleoside, 6-Modified purine nucleoside, Halo-nucleoside, 3'-Modified nucleoside; Scaffold and Template.
T25287 Dansyllysine

Dns-lysine

Others Others
Dansyllysine is utilized to study binding conformations of drugs to human serum albumin and is utilized as a template molecule to form molecularly imprinted monolayers (MIMs) useful to produce optical biosensor recognition elements.
TNU0982 2-Amino-6-chloro-9-(3-deoxy-2-O-acetyl-5-O-benzoyl-beta-D-ribofuanosyl)-9H-purine

Others Others
2-Amino-6-chloro-9-(3-deoxy-2-O-acetyl-5-O-benzoyl-beta-D-ribofuanosyl)-9H-purine is a Nucleoside Derivative - 3'-Deoxy nucleoside, Halo-nucleoside; Scaffold and Template.
TNU0878 N-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl  propanamide

Others Others
N-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl propanamide belongs to Heterocyclic Compounds - Purine; Intermediates and Building Blocks - Nucleoside base, Electrophile; Scaffold and Template.
TNU1035 3,6-Dibromo-1,5-dihydro-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one

Others Others
3,6-Dibromo-1,5-dihydro-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one is a Nucleoside Derivative - 7-Deaza-8-aza-purine nucleoside; Halo-nucleoside; Scaffold and Template.
TNU1033 4-Amino-6-bromo-5-cyano-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine

Others Others
4-Amino-6-bromo-5-cyano-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a Nucleoside Derivative - 7-Deaza-purine nucleoside, 8-Modified-purine nucleoside, Halo-nucleoside; Scaffold and Template.
T24919 UBP714

UBP 714,UBP-714

Others Others
UBP714 is a derivative of the NMDA receptor negative allosteric modulator UBP608. It also enhanced NMDAR mediated field EPSPs in the CA1 region of the hippocampus. UBP714 is a novel template for the development of potent and subunit selective NMDAR potent
T78736 D3R ligand 1

Dopamine Receptor GPCR/G Protein; Neuroscience
D3R ligand 1 (compound 23b) 是针对多巴胺受体D3R具有高效选择性的配体,拥有66 nM的Ki值,且包含THPB模板。此外,D3R ligand 1 同时作为基于G蛋白及β-arrestin信号传导路径的拮抗剂。
T61886 HBV-IN-16

Others Others
HBV-IN-16 是一种有效的共价闭合环状 DNA (cccDNA) 抑制剂。cccDNA 作为病毒 RNA 转录和随后病毒 DNA 生成的模板。HBV-IN-16 是一种喹啉衍生物。HBV-IN-16 具有研究 HBV 感染的潜力 。
T81422 Pomalidomid-C6-PEG3-butyl-N3

PROTACs PROTAC
Pomalidomid-C6-PEG3-butyl-N3为具有叠氮基的点击化学试剂,同时作为交联剂-E3连接酶配体偶联物,它在PROTAC领域用于点击反应蛋白降解剂构建块,以及靶向蛋白降解剂合成的模板。
T82916 BChE-IN-20

Others Others
BChE-IN-20(compound 7c)作为一种BChE选择性抑制剂显示出高效性,其对eqBChE的IC50为105 nM,对hBChE的IC50为2.3 nM。同时,BChE-IN-20对P糖蛋白的IC50值为0.27 μM。此化合物为BChE选择性配体的设计与开发,包括抑制剂与荧光探针,提供了一个有潜力的模板。
T83123 Amyloid β-Protein (3-42)

Amyloid β-Protein (3-42) 为Pyr肽前体, 其焦谷氨酸修饰的形式 Aβ (pEAβ) (3-42) 构成阿尔茨海默病淀粉样斑块的关键。pEAβ (3-42) 能促进 Aβ(1-42) 聚集,并且 Aβ(1-42) 显著延缓pEAβ(3-42) 的初级及次级成核过程。
T35693 N-(2-Azidoethyl)betulonamide

Others Others
N-(2-Azidoethyl)betulonamide is a pentacyclic triterpenoid, a derivative of betulonic acid , and an intermediate in the synthesis of betulonic acid derivatives within vitrocancer cell cytotoxicity.1 1.Suman, P., Patel, A., Solano, L., et al.Synthesis and cytotoxicity of Baylis-Hillman template derived betulinic acid-triazole conjugatesTetrahedron73(29)4214-4226(2017)
T35658 3'-Deoxyuridine-5'-triphosphate trisodium

Others Others
3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate trisodium strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1]. 3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is synthesized starting from cordycepin in good yield. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA by the RNA polym...
T35657 3'-Deoxyuridine-5'-triphosphate

Others Others
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA with a Ki value of 2.0 μM[1]. 3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is synthesized starting from cordycepin in good yield. 3'-Deoxyuridine-5'-triphosphate strongly and competitively inhibits the incorporations of UTP into RNA by the RNA polymerases. 3'-Deoxyuridine-5'-tri...

化合物

Sucrose octaacetate
Cat.No: T16949
Synonym:
Target: Others
Glycylglycine
Cat.No: T5286
Synonym: Glycyl-glycine,Glycine dipeptide,Diglycocoll,Diglycine,Gly-gly,双甘肽,N-Glycylglycine
Target: Others, Endogenous Metabolite
Quarfloxin
Cat.No: T16703
Synonym: CX-3543
Target: DNA/RNA Synthesis
2-Iodo-2’-deoxyadenosine
Cat.No: TNU1075
Synonym:
Target: Others
2,6-Dichloro-2',3',5'-triacetyl-purine riboside
Cat.No: TNU1278
Synonym:
Target: Others
8-Aza-7-bromo-7-deazaguanosine
Cat.No: TNU0275
Synonym:
Target: Others
6-Chloro-7-fluoro-7-deazapurine
Cat.No: TNU1013
Synonym:
Target: Others
6-Chloro-2-iodo-9-(2,3,5-tri-O-acetyl)-beta-D-ribofuranosyl-9H-purine
Cat.No: TNU0879
Synonym:
Target: Others
6-Bromopyrazolo[3,4-d]pyrimidin-4(5H)-one
Cat.No: TNU1016
Synonym:
Target: Others
4-Amino-6-bromo-5-cyano-7H-pyrrolo[2,3-d]pyrimidine
Cat.No: TNU1015
Synonym:
Target: Others
5-(2-Hydroxyethyl)uracil
Cat.No: TNU0870
Synonym:
Target: Others
N-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl  propanamide
Cat.No: TNU0877
Synonym:
Target: Others
5-Pyrrolidinomethyluridine
Cat.No: TNU0121
Synonym:
Target: Others
5-(3-Hydroxypropyl)uracil
Cat.No: TNU0872
Synonym:
Target: Others
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-2-chloro-6-(thiophen-3-yl)purine
Cat.No: TNU0760
Synonym:
Target: Others
6-Amino-4-chloropyrazolo[3,4-d]pyrimidine
Cat.No: TNU1018
Synonym:
Target: Others
5-(2-Hydroxyethyl)-2-thiouracil
Cat.No: TNU0871
Synonym:
Target: Others
4-Chloro-7-[(5-O-t-butyldimethylsilyl)-2,3-O-isopropyli-dene-β-D-ribofuranosyl]-7H-pyrrolo[2,3-d]pyrimidine
Cat.No: TNU1068
Synonym:
Target: Others
3,6-Dibromopyrazolo[3,4-d]pyrimidin-4(5H)-one
Cat.No: TNU1017
Synonym:
Target: Others
5-(2-Hyroxyethyl)-2’,3’-di-O-toluoyl-2’-deoxyuridine
Cat.No: TNU1279
Synonym:
Target: Others
2-Bromo-2’-deoxyadenosine
Cat.No: TNU1074
Synonym:
Target: Others
6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine
Cat.No: TNU1019
Synonym:
Target: Others
6-Amino-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine
Cat.No: TNU1020
Synonym:
Target: Others
4-Chloro-7-(2,3-O-isopropylidene-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
Cat.No: TNU1069
Synonym:
Target: Others
5’-O-(p-Toluoyl)-2’-O-acetyl-3’-deoxy-3’-fluoro-6-chloroinosine
Cat.No: TNU0632
Synonym:
Target: Others
6-Chloro-2-bromo-9-(2,3,5-tri-O-acetyl)-beta-D-ribofuranosyl-9H-purine
Cat.No: TNU1073
Synonym:
Target: Others
4-Amino-6-bromo-5-cyano-1-(beta-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine
Cat.No: TNU1034
Synonym:
Target: Others
2-Amino-6-chloro-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine
Cat.No: TNU0090
Synonym:
Target: Others
2-Amino-6-chloro-9-(3-deoxy-beta-D-ribofuanosyl)-9H-purine
Cat.No: TNU0983
Synonym:
Target: Others
9-(2’-O-Acetyl-5’-O-benzoyl-3’-deoxy-beta-D-ribofuranosyl)-6-chloropurine
Cat.No: TNU0981
Synonym:
Target: Others
4-Amino-5-iodo-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
Cat.No: TNU0103
Synonym:
Target: Others
4-Chloro-7-(2-b-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]   pyrimidine
Cat.No: TNU0102
Synonym:
Target: Others
2-Chloro-6-(furan-2-yl)purine-beta-D-(3’-deoxy-3’-fluoro)riboside
Cat.No: TNU0088
Synonym:
Target: Others
Dansyllysine
Cat.No: T25287
Synonym: Dns-lysine
Target: Others
2-Amino-6-chloro-9-(3-deoxy-2-O-acetyl-5-O-benzoyl-beta-D-ribofuanosyl)-9H-purine
Cat.No: TNU0982
Synonym:
Target: Others
N-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethyl  propanamide
Cat.No: TNU0878
Synonym:
Target: Others
3,6-Dibromo-1,5-dihydro-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one
Cat.No: TNU1035
Synonym:
Target: Others
4-Amino-6-bromo-5-cyano-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine
Cat.No: TNU1033
Synonym:
Target: Others
UBP714
Cat.No: T24919
Synonym: UBP 714,UBP-714
Target: Others
D3R ligand 1
Cat.No: T78736
Synonym:
Target: Dopamine Receptor
HBV-IN-16
Cat.No: T61886
Synonym:
Target: Others
Pomalidomid-C6-PEG3-butyl-N3
Cat.No: T81422
Synonym:
Target: PROTACs
BChE-IN-20
Cat.No: T82916
Synonym:
Target: Others
Amyloid β-Protein (3-42)
Cat.No: T83123
Synonym:
Target:
N-(2-Azidoethyl)betulonamide
Cat.No: T35693
Synonym:
Target: Others
3'-Deoxyuridine-5'-triphosphate trisodium
Cat.No: T35658
Synonym:
Target: Others
3'-Deoxyuridine-5'-triphosphate
Cat.No: T35657
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
TJS0311 Ethyl 3-coumarincarboxylate

3-Ethoxycarbonylcoumarin,香豆素-3-羧酸乙酯,香豆素-3-羧酸乙素,Ethyl 2-Oxo-2H-Chromene-3-Carboxylate,Ethyl coumarin-3-carboxylate,3-Carbethoxycoumarin

Others Others
Ethyl coumarin-3-carboxylate 是香豆素衍生物。它可作为一种伪模板,制备能够特异性识别黄曲霉毒素的分子印迹聚合物 (MIP)。
T13592 Calf thymus DNA

DNA from calf thymus, Thymonucleic acid

DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Calf thymus DNA (DNA from calf thymus, Thymonucleic acid) 是一种从牛胸腺中提取出来的高质量双链模板DNA,可广泛应用于DNA 结合抗癌剂和调节DNA 结构和功能的DNA 结合剂的研究。

天然产物

Ethyl 3-coumarincarboxylate
Cat.No: TJS0311
Synonym: 3-Ethoxycarbonylcoumarin,香豆素-3-羧酸乙酯,香豆素-3-羧酸乙素,Ethyl 2-Oxo-2H-Chromene-3-Carboxylate,Ethyl coumarin-3-carboxylate,3-Carbethoxycoumarin
Target: Others
Calf thymus DNA
Cat.No: T13592
Synonym: DNA from calf thymus, Thymonucleic acid
Target: DNA/RNA Synthesis
Cat. No. Product Name Species Expression System
TMPY-02543 PCNA Protein, Human, Recombinant (His)

ATLD2,proliferating cell nuclear antigen

Human Baculovirus Insect Cells
Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. It is central to both DNA replication and repair. One of the well-established functions for PCNA is its role as the processivity factor for DNA polymerase delta and epsilon. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. Two forms of PCNA exist in cells: (i) a detergent-insoluble trimeric form stably associated with the replic...
TMPH-01674 Human metapneumovirus (strain CAN97-83) Nucleoprotein/NP Protein (His & Myc)

Nucleoprotein,N,Nucleocapsid protein

HMPV E. coli
Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases. RNA replication depends on the availability of soluble nucleoprotein. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.
TMPH-03416 Rift valley fever virus (RVFV) (strain ZH-548 M12) Nucleoprotein/NP Protein (His & SUMO)

N,Nucleoprotein,Nucleocapsid protein

RVFV E. coli
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles. Rift valley fever virus (RVFV) (strain ZH-548 M12) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43....
TMPH-00360 DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant

Exodeoxyribonuclease large subunit,DNA polymerase II large s...

Cenarchaeum symbiosum E. coli
Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 59.0 kDa and the accession number is A0RYM0.
TMPH-00316 Bunyavirus La Crosse Nucleoprotein/NP Protein (His)

Nucleoprotein,Protein N,Nucleocapsid protein,N

Bunyavirus La Crosse P. pastoris (Yeast)
Encapsidates the genome protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication. Seems to participate in the nuclear relocalization of host PABP1, thereby inhibiting host cellular translation. Bunyavirus La Crosse Nucleoprotein/NP Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 28.5 kDa and the accession number is P04873.
TMPH-03729 Zaire ebolavirus (strain Kikwit-95) VP30 Protein (His)

Transcriptional activator VP30,EbolaVP30,Minor nucleoprotein...

ZEBOV E. coli
Multifunctional protein that acts as a viral transcriptional activator. Promotes read-through of an RNA hairpin in the NP open reading frame to enhance viral transcription. Mechanistically, nonphosphorylated VP30 hexamers form a ternary complex with the viral leader RNA. Clamps the RNA template and the complex VP35-polymerase L together, thereby increasing the polymerase affinity for the RNA template to increase transcription initiation despite the presence of RNA secondary structures. Assists a...
TMPH-02711 H2B type 1-M Protein, Mouse, Recombinant (His)

Histone H2B type 1-M,H2bc14,H2B 291B

Mouse E. coli
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. HIST1H2BM Protein, Mouse, Recombinant (His) is expressed in E...
TMPH-00741 Rho Protein, E. coli, Recombinant (His)

Transcription termination factor Rho,ATP-dependent helicase ...

E. coli E. coli
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPase which utilizes all four ribonucleoside triphosphates as substrates. Rho Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 51.0 kDa and the accession number is P0AG30.
TMPH-02186 TERT Protein, Human, Recombinant (His)

Telomerase reverse transcriptase,Telomerase catalytic subuni...

Human E. coli
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-de...
TMPH-03698 VSIV (strain Glasgow) Phosphoprotein Protein (His & Myc)

Phosphoprotein,P,Protein M1

VSIV E. coli
Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template. May act as a chaperone for newly synthesized free N protein, so-called N(0). Plays a role in virion assembly. VSIV (strain Glasgow) Phosphoprotein Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.9 kDa and the accession number is P04879.
TMPH-01843 Human parainfluenza 4b virus (HPIV-4b) Nucleoprotein/NP Protein (His)

Nucleoprotein,Nucleocapsid protein,N

HPIV-4b E. coli
Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. Human parainfluenza 4b virus (HPIV-4b) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 68.5 ...
TMPH-01247 POLR3K Protein, Human, Recombinant (His)

RNA polymerase III subunit C11,POLR3K,RNA polymerase III 12....

Human Baculovirus Insect Cells
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase I...
TMPH-01246 POLR3A Protein, Human, Recombinant (His)

RNA polymerase III subunit C160,RNA polymerase III 155 kDa s...

Human E. coli
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft ...
TMPH-03696 VSIV (strain San Juan) Nucleoprotein/NP Protein (His & Myc)

Nucleocapsid protein,N,Nucleoprotein

VSIV E. coli
Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. Nucleocapsid assembly is concommitant with replication, therefore viral replication depends on the intracellular concentration of free N, termed N(0). All replicative products are resistant to nucleases. VSIV (strain San Juan) Nucleoprotein/NP Protein (His & Myc) is expressed in E. coli expressi...
TMPH-02380 RPB5 Protein, Kluyveromyces marxianus, Recombinant (His)

RPB5,DNA-directed RNA polymerases I, II, and III subunit RPA...

Kluyveromyces marxianus E. coli
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol...
TMPH-01841 Human parainfluenza 1 virus (HPIV-1) Nucleoprotein/NP Protein (His)

Nucleoprotein,Nucleocapsid protein,N

HPIV-1 E. coli
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. Human parainfluenza 1 virus (HPIV-1) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with N-10xHis tag. T...
TMPH-00811 Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc)

Small delta antigen,p24

HDV P. pastoris (Yeast)
Promotes both transcription and replication of genomic RNA. Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal. May interact with host RNA polymerase II thereby changing its template requirement from DNA to RNA. RNA pol II complex would then acts as an RNA-directed RNA polymerase, and transcribe and replicate HDV genome. Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc) is expressed in yeast with N-6xHi...
TMPY-00323 Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)

NS3

HCV E. coli
HCV NS3 displays three enzymatic activities: serine protease, NTPase, and RNA helicase. HCV NS3 serine protease, in association with NS4A, is responsible for the cleavages of NS3-NS4A, NS4A-NS4B, NS4B-NS5A, and NS5A-NS5B. HCV NS3 RNA helicase binds to RNA and unwinds dsRNA in the 3' to 5' direction, and likely RNA stable secondary structure in the template strand (By similarity). Cleaves and inhibits the host antiviral protein MAVS. NS3/NS4A complex also prevents phosphorylation of human IRF3, t...
TMPH-02351 Influenza A H3N2 (strain A/Beijing/353/1989) Nucleoprotein/NP Protein (His & SUMO)

Nucleoprotein,NP,Nucleocapsid protein

H3N2 E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw...
TMPH-02353 Influenza A H1N1 (strain A/Fort Warren/1/1950) Nucleoprotein/NP Protein (His & SUMO)

Nucleocapsid protein,Nucleoprotein,NP

H1N1 E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw...
TMPH-02354 Influenza A H1N1 (strain A/New Jersey/8/1976) Nucleoprotein/NP Protein (His & SUMO)

NP,Nucleocapsid protein,Nucleoprotein

H1N1 E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw...
TMPH-02355 Influenza A H3N2 (strain A/Port Chalmers/1/1973) Nucleoprotein/NP Protein (His & SUMO)

NP,Nucleoprotein,Nucleocapsid protein

H3N2 E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw...
TMPH-02350 Influenza A H3N2 (strain A/Shanghai/16/1989) Nucleoprotein/NP Protein (His)

NP,Nucleocapsid protein,Nucleoprotein

H3N2 E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw...
TMPY-01332 HIST1H3A Protein, Human, Mouse, Recombinant

Histone H3.1,histone cluster 1, H3a,Histone H3

Human,Mouse E. coli
Histone H3.1, also known as HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, is a member of the histone H3 family which is a core component of nucleosome. It is expressed during the S phase, then expression strongly decreases as cell division slows down during the process of differentiation. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machinery which requires DNA as a template. Histones thereby pla...
TMPH-02352 Influenza A H3N2 (strain A/Kitakyushu/159/1993) Nucleoprotein/NP Protein (His)

Nucleocapsid protein,NP,Nucleoprotein

H3N2 E. coli
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathw...
TMPH-01001 BCL10 Protein, Human, Recombinant (His & SUMO)

B-cell lymphoma/leukemia 10,cCARMEN,hCLAP,CIPER,CLAP,BCL10,B...

Human E. coli
Plays a key role in both adaptive and innate immune signaling by bridging CARD domain-containing proteins to immune activation. Acts by channeling adaptive and innate immune signaling downstream of CARD domain-containing proteins CARD9, CARD11 and CARD14 to activate NF-kappa-B and MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) pathways which stimulate expression of genes encoding pro-inflammatory cytokines and chemokines. Recruited by activated CARD domain-containing proteins: homooligome...
TMPH-01238 POLQ Protein, Human, Recombinant (His)

DNA polymerase eta,POLQ,DNA polymerase theta

Human Baculovirus Insect Cells
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions, some of them leading to cellular transformation. POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumul...
TMPH-01288 Elongin-B Protein, Human, Recombinant (GST)

EloB,Elongin-B,TCEB2,ELOB,SIII p18

Human E. coli
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region ...
TMPH-01237 POLQ Protein, Human, Recombinant (E. coli, His)

DNA polymerase eta,POLQ,DNA polymerase theta

Human E. coli
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions, some of them leading to cellular transformation. POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumul...

重组蛋白

PCNA Protein, Human, Recombinant (His)
Cat.No: TMPY-02543
Species: Human
Expression System: Baculovirus Insect Cells
Human metapneumovirus (strain CAN97-83) Nucleoprotein/NP Protein (His & Myc)
Cat.No: TMPH-01674
Species: HMPV
Expression System: E. coli
Rift valley fever virus (RVFV) (strain ZH-548 M12) Nucleoprotein/NP Protein (His & SUMO)
Cat.No: TMPH-03416
Species: RVFV
Expression System: E. coli
DNA polymerase II large subunit Protein, Cenarchaeum symbiosum, Recombinant
Cat.No: TMPH-00360
Species: Cenarchaeum symbiosum
Expression System: E. coli
Bunyavirus La Crosse Nucleoprotein/NP Protein (His)
Cat.No: TMPH-00316
Species: Bunyavirus La Crosse
Expression System: P. pastoris (Yeast)
Zaire ebolavirus (strain Kikwit-95) VP30 Protein (His)
Cat.No: TMPH-03729
Species: ZEBOV
Expression System: E. coli
H2B type 1-M Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02711
Species: Mouse
Expression System: E. coli
Rho Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00741
Species: E. coli
Expression System: E. coli
TERT Protein, Human, Recombinant (His)
Cat.No: TMPH-02186
Species: Human
Expression System: E. coli
VSIV (strain Glasgow) Phosphoprotein Protein (His & Myc)
Cat.No: TMPH-03698
Species: VSIV
Expression System: E. coli
Human parainfluenza 4b virus (HPIV-4b) Nucleoprotein/NP Protein (His)
Cat.No: TMPH-01843
Species: HPIV-4b
Expression System: E. coli
POLR3K Protein, Human, Recombinant (His)
Cat.No: TMPH-01247
Species: Human
Expression System: Baculovirus Insect Cells
POLR3A Protein, Human, Recombinant (His)
Cat.No: TMPH-01246
Species: Human
Expression System: E. coli
VSIV (strain San Juan) Nucleoprotein/NP Protein (His & Myc)
Cat.No: TMPH-03696
Species: VSIV
Expression System: E. coli
RPB5 Protein, Kluyveromyces marxianus, Recombinant (His)
Cat.No: TMPH-02380
Species: Kluyveromyces marxianus
Expression System: E. coli
Human parainfluenza 1 virus (HPIV-1) Nucleoprotein/NP Protein (His)
Cat.No: TMPH-01841
Species: HPIV-1
Expression System: E. coli
Hepatitis delta virus genotype I (HDV) Small delta antigen Protein (His & Myc)
Cat.No: TMPH-00811
Species: HDV
Expression System: P. pastoris (Yeast)
Hepatitis C virus (HCV-1a) NS3 protease/helicase immunodominant region Protein (aa 1356-1459, GST)
Cat.No: TMPY-00323
Species: HCV
Expression System: E. coli
Influenza A H3N2 (strain A/Beijing/353/1989) Nucleoprotein/NP Protein (His & SUMO)
Cat.No: TMPH-02351
Species: H3N2
Expression System: E. coli
Influenza A H1N1 (strain A/Fort Warren/1/1950) Nucleoprotein/NP Protein (His & SUMO)
Cat.No: TMPH-02353
Species: H1N1
Expression System: E. coli
Influenza A H1N1 (strain A/New Jersey/8/1976) Nucleoprotein/NP Protein (His & SUMO)
Cat.No: TMPH-02354
Species: H1N1
Expression System: E. coli
Influenza A H3N2 (strain A/Port Chalmers/1/1973) Nucleoprotein/NP Protein (His & SUMO)
Cat.No: TMPH-02355
Species: H3N2
Expression System: E. coli
Influenza A H3N2 (strain A/Shanghai/16/1989) Nucleoprotein/NP Protein (His)
Cat.No: TMPH-02350
Species: H3N2
Expression System: E. coli
HIST1H3A Protein, Human, Mouse, Recombinant
Cat.No: TMPY-01332
Species: Human,Mouse
Expression System: E. coli
Influenza A H3N2 (strain A/Kitakyushu/159/1993) Nucleoprotein/NP Protein (His)
Cat.No: TMPH-02352
Species: H3N2
Expression System: E. coli
BCL10 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01001
Species: Human
Expression System: E. coli
POLQ Protein, Human, Recombinant (His)
Cat.No: TMPH-01238
Species: Human
Expression System: Baculovirus Insect Cells
Elongin-B Protein, Human, Recombinant (GST)
Cat.No: TMPH-01288
Species: Human
Expression System: E. coli
POLQ Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01237
Species: Human
Expression System: E. coli
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