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Search Results for " serotonin 3 receptor "
Targets Recommended: 5-HT Receptor AChR

24

抑制剂 & 化合物

2

天然产物

59

重组蛋白

3

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T28531 Facinicline hydrochloride

RG3487

5-HT Receptor; AChR GPCR/G Protein; Neuroscience
Facinicline hydrochloride (RG3487) 是一种口服有效的烟碱α7 receptor 部分激动剂,对人 nAChR 的 Ki 值为 6 nM。它可改善啮齿类动物的认知和感觉运动门控。它与5-HT3受体结合的 Ki 为 1.2 nM。
T8593 RU 24969 free base

5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

5-HT Receptor GPCR/G Protein; Neuroscience
RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) 是 5-HT1A 和 5-HT1B 受体的选择性激动剂,Ki 值分别为 0.38 和 2.5 nM。它可减少液体消耗并增加向前运动。
T7350 Nelotanserin

1-[3-(4-溴-1-甲基-1H-吡唑-5-基)-4-甲氧基苯基]-3-(2,4-二氟苯基)脲,APD125

5-HT Receptor GPCR/G Protein; Neuroscience
Nelotanserin (APD125) 是5-HT2A 强完全逆向激动剂,5-HT2C 中等强度的部分反向激动剂和5-HT2B 的弱反向激动剂,IC50s 值分别为 1.7、79 和 791 nM。
T4266 LY334370

4-氟-N-(3-(1-甲基哌啶-4-基)-1H-吲哚-5-基)苯甲酰胺盐酸盐,LY 334370

5-HT Receptor GPCR/G Protein; Neuroscience
LY334370 是一种选择性5-HT1F 受体激动剂,Ki 值为 1.6 nM。
T7277 SB 242084

6 - 氯-2,3 - 二氢- 5 -甲基- N - [6 - [(2 - 甲基-3 - 吡啶基)氧] -3 - 吡啶基] - 1H -吲哚- 1 - 酰胺盐酸盐,SB 242084 dihydrochloride hydrate

5-HT Receptor GPCR/G Protein; Neuroscience
SB 242084 是5-HT2C 选择性抑制剂,pKi 值9.0,是一种精神活性药物和研究化学品。
T1042 Granisetron hydrochloride

盐酸格拉司琼,BRL 43694A,Granisetron HCl

5-HT Receptor GPCR/G Protein; Neuroscience
Granisetron hydrochloride (Granisetron HCl) 是一种5-HT3受体拮抗剂,可作为化疗后止吐剂。
T8441 Lerisetron

5-HT Receptor GPCR/G Protein; Neuroscience
Lerisetron 是5-HT3拮抗剂,与 5-HT3受体具有高亲和力(pKi:9.2)。它对尿烷麻醉大鼠的 5-HT 引发的反射性心率过缓具有抑制作用。
T50011 CYP2A6-IN-1

Others Others
(2-methylpropyl)({[3-(trifluoromethyl)phenyl]methyl})amine 是一种选择性血清素受体激动剂,特异性靶向5-HT2A 和5-HT2C 受体,已被用于研究血清素在各种生理和病理条件下的作用。
T1173 Tropisetron hydrochloride

SDZ-ICS 930,Tropisetron HCl,ICS 205-930,盐酸托烷司琼

5-HT Receptor GPCR/G Protein; Neuroscience
Tropisetron hydrochloride (Tropisetron HCl) 是5-HT3受体拮抗剂和α7-烟碱受体激动剂,具有抗恶心和止吐活性,对5-HT3受体的 IC50为70.1 nM。
T1478 Ondansetron hydrochloride dihydrate

盐酸昂丹司琼,SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride

5-HT Receptor GPCR/G Protein; Neuroscience
Ondansetron hydrochloride dihydrate (GR 38032) 是5- HT3受体拮抗剂,可治疗化疗后的恶心和呕吐,有抗焦虑和抗精神病作用。
T50089 2-(5,7-dichloro-1H-indol-3-yl)ethan-1-amine

Others Others
2-(5,7-dichloro-1H-indol-3-yl)ethan-1-amine 是一种吲哚胺类化合物,在结构上与血清素相似。它是5-HT2A 受体的选择性激动剂,在神经科学领域具有潜在的应用。
T50039 3-(2-aminopropyl)phenol hydrochloride

Others Others
3-(2-aminopropyl)phenol hydrochloride 是一种用作分子结构单元的苯乙胺类化合物。它是一种精神活性药物,是5-HT1A、5-HT1B 和5-HT2C 等几种血清素受体的部分激动剂,也是5-HT2A 受体的拮抗剂。
T71046 FK-1052

Others Others
FK-1052 is a serotonin 3 & 4 dual receptor antagonist.
T71045 FK-1052 HCl

Others Others
FK-1052 HCl is a serotonin 3 & 4 dual receptor antagonist.
T22340 Granisetron

Sustol,Granisetronum,格拉司琼,Sancuso,Kevatril

5-HT Receptor GPCR/G Protein; Neuroscience
Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy.
T27675 JNJ-28583867

JNJ28583867

Others Others
JNJ-28583867 is an inhibitor of histamine H(3) receptor antagonist and serotonin reuptake.
T27607 Indisetron Dihydrochloride

N3389T,Sinseron,N-3389T,N 3389T

Others Others
Indisetron Dihydrochloride is a 5-HT(3) and 5-HT(4) receptor antagonist. Indisetron reduces 2-methyl-5-serotonin (HT)-induced bradycardia.
T70729 Indisetron

Others Others
Indisetron is a 5-HT(3) and 5-HT(4) receptor antagonist. Indisetron reduces 2-methyl-5-serotonin (HT)-induced bradycardia.
T61011 Izuforant

Others Others
Izuforant (JW1601) (Compound 24) 具有有效的抗炎和止痒活性。 Izuforant 对人血清素3受体 (h5-HT3R) 具有结合亲和力,IC50值为 9.1 μM。它也是组胺 H4 受体 (H4R) 的口服活性拮抗剂,对人 H4R 的IC50值为 36 nM。
T37246 Palonosetron N-oxide

Others Others
Palonosetron N-oxide is a metabolite of the serotonin (5-HT) receptor subtype 5-HT3antagonist palonosetron .1It is also a potential impurity in palonosetron preparations.2Palonosetron N-oxide is a degradation product formed by exposure to oxidative stress. 1.Stoltz, R.A., Cyong, J.-C., Shah, A., et al.Pharmacokinetic and safety evaluation of palonosetron, a 5-hydroxytryptamine-3 receptor antagonist, in U.S. and Japanese healthy subjectsJ. Clin. Pharmacol.44(5)520-531(2004) 2.Vishnu Murthy, M., S...
T10294 AM9405

5-HT Receptor GPCR/G Protein; Neuroscience
AM9405是一种新型的外周活性大麻素1型 (CB1)和5-羟色胺3型受体激动剂。 AM9405抑制回肠和结肠的抽搐收缩,IC50分别为45.71 和 0.076 nM。AM9405 在生理条件下显着减缓小鼠肠道蠕动.
T83776 Dopamine D3 Receptor Agonist 13a

Dopamine D3 受体激动剂13a是一种Dopamine D3 受体激动剂。该化合物选择性地与Dopamine D3 受体结合,相较于Dopamine D1、D2和D4受体(Kis = 0.14、4,600、2.85和756 nM,分别)具有更高的亲和力,并且还能与血清素(5-HT)受体亚型5-HT1A、5-HT2A、5-HT2B和5-HT2C(Kis = 6、54、1.47和252 nM,分别)结合;然而,它是Dopamine D2受体的部分激动剂(EC50 = 2.26 nM,在G蛋白招募分析中)并且作为Dopamine D3受体的拮抗剂(IC50 = 4.62 nM)。在大鼠身上,当剂量为3 mg/kg时,Dopamine D3 受体激动剂13a能减少可卡因自我给药。
T36639 Donecopride (fumarate hydrate)

Others Others
Donecopride is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT4E(Ki= 8.5 nM) and an inhibitor of acetylcholinesterase (AChE; IC50= 16 nM).1It is selective for AChE over butyrylcholinesterase (BChE; IC50= 3,530 nM) but does bind to 5-HT2Band sigma-2 (σ2) receptors (Ki= 1.6 nM for both) in a panel of 42 neurotransmitter receptors and transporters. Donecopride induces release of soluble amyloid precursor protein-α (sAPP-α) in COS-7 cells transiently expressing 5-HT4with an EC50value...
T38145 Eltoprazine

Others Others
Eltoprazine(DU28853) is a serenic or antiaggressive agent which as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor.IC50 value:Target: 5-HT1A/1B agonist; 5-HT2C antagonistin vitro: The binding of [3H]eltoprazine to whole tissue sections was saturable and revealed an apparent dissociation constant (Kd) of 11 nM. Specific [3H]eltoprazine binding was completely displaced by 5-HT; conversely, unlabelled eltoprazine reduced [3H]5-HT binding to the levels of no...

化合物

Facinicline hydrochloride
Cat.No: T28531
Synonym: RG3487
Target: 5-HT Receptor, AChR
RU 24969 free base
Cat.No: T8593
Synonym: 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Target: 5-HT Receptor
Nelotanserin
Cat.No: T7350
Synonym: 1-[3-(4-溴-1-甲基-1H-吡唑-5-基)-4-甲氧基苯基]-3-(2,4-二氟苯基)脲,APD125
Target: 5-HT Receptor
LY334370
Cat.No: T4266
Synonym: 4-氟-N-(3-(1-甲基哌啶-4-基)-1H-吲哚-5-基)苯甲酰胺盐酸盐,LY 334370
Target: 5-HT Receptor
SB 242084
Cat.No: T7277
Synonym: 6 - 氯-2,3 - 二氢- 5 -甲基- N - [6 - [(2 - 甲基-3 - 吡啶基)氧] -3 - 吡啶基] - 1H -吲哚- 1 - 酰胺盐酸盐,SB 242084 dihydrochloride hydrate
Target: 5-HT Receptor
Granisetron hydrochloride
Cat.No: T1042
Synonym: 盐酸格拉司琼,BRL 43694A,Granisetron HCl
Target: 5-HT Receptor
Lerisetron
Cat.No: T8441
Synonym:
Target: 5-HT Receptor
CYP2A6-IN-1
Cat.No: T50011
Synonym:
Target: Others
Tropisetron hydrochloride
Cat.No: T1173
Synonym: SDZ-ICS 930,Tropisetron HCl,ICS 205-930,盐酸托烷司琼
Target: 5-HT Receptor
Ondansetron hydrochloride dihydrate
Cat.No: T1478
Synonym: 盐酸昂丹司琼,SN 307,NSC 665799,GR 38032,Ondansetron hydrochloride
Target: 5-HT Receptor
2-(5,7-dichloro-1H-indol-3-yl)ethan-1-amine
Cat.No: T50089
Synonym:
Target: Others
3-(2-aminopropyl)phenol hydrochloride
Cat.No: T50039
Synonym:
Target: Others
FK-1052
Cat.No: T71046
Synonym:
Target: Others
FK-1052 HCl
Cat.No: T71045
Synonym:
Target: Others
Granisetron
Cat.No: T22340
Synonym: Sustol,Granisetronum,格拉司琼,Sancuso,Kevatril
Target: 5-HT Receptor
JNJ-28583867
Cat.No: T27675
Synonym: JNJ28583867
Target: Others
Indisetron Dihydrochloride
Cat.No: T27607
Synonym: N3389T,Sinseron,N-3389T,N 3389T
Target: Others
Indisetron
Cat.No: T70729
Synonym:
Target: Others
Izuforant
Cat.No: T61011
Synonym:
Target: Others
Palonosetron N-oxide
Cat.No: T37246
Synonym:
Target: Others
AM9405
Cat.No: T10294
Synonym:
Target: 5-HT Receptor
Dopamine D3 Receptor Agonist 13a
Cat.No: T83776
Synonym:
Target:
Donecopride (fumarate hydrate)
Cat.No: T36639
Synonym:
Target: Others
Eltoprazine
Cat.No: T38145
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T4429 Rauwolscine hydrochloride

Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride

Adrenergic Receptor GPCR/G Protein; Neuroscience
Rauwolscine hydrochloride (Isoyohimbine hydrochloride) 是一种高选择性的 α2 adrenergic 受体拮抗剂,Ki=12 nM。
T6S1684 8-Gingerol

Antioxidant; Antibacterial; TRP/TRPV Channel Membrane transporter/Ion channel; Microbiology/Virology; oxidation-reduction
8-Gingerol 分离自姜的根状茎,是口服有效的 TRPV1激活剂,EC50值为5.0 µM。8-Gingerol 抑制 COX-2,还能抑制体外 H. pylori 的生长。

天然产物

Rauwolscine hydrochloride
Cat.No: T4429
Synonym: Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride
Target: Adrenergic Receptor
8-Gingerol
Cat.No: T6S1684
Synonym:
Target: Antioxidant, Antibacterial, TRP/TRPV Channel
Cat. No. Product Name Species Expression System
TMPY-06986 FGF-8b Protein, Human, Recombinant

NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8...

Human E. coli
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac...
TMPY-00132 Mesothelin Protein, Human, Recombinant

MPF,SMRP,Mesothelin

Human HEK293 Cells
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3.
TMPY-04935 CD47 Protein, Human, Recombinant (aa 1-139, His)

MER6,CD47 molecule,IAP,OA3

Human HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3.
TMPY-03763 Neuropilin-2 Protein, Human, Recombinant (hFc)

Neuropilin-2,NPN2,neuropilin 2,PRO2714,VEGF165R2,NP2

Human HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3.
TMPY-05191 CD47 Protein, Human, Recombinant, Biotinylated

CD47 molecule,MER6,OA3,IAP

Human HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-00072 GITR/TNFRSF18 Protein, Human, Recombinant (His)

AITR,GITR-D,tumor necrosis factor receptor superfam...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3.
TMPY-04683 CD47 Protein, Human, Recombinant

MER6,CD47 molecule,OA3,IAP

Human HEK293 Cells
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.
TMPY-00892 Neuropilin-2 Protein, Human, Recombinant (His)

NP2,PRO2714,VEGF165R2,neuropilin 2,NPN2,Neuropilin-2

Human HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3.
TMPY-01897 PRSS3 Protein, Human, Recombinant (His)

PRSS4,TRY4,TRY3,RP11-176F3.3,T9,M...

Human HEK293 Cells
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPY-01020 Periostin/OSF-2 Protein, Human, Recombinant (His)

PN,OSF-2,OSF2,periostin,periostin, osteoblast specific facto...

Human HEK293 Cells
Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3.
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc)

OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis factor

Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3.
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His)

L-CA,T200,LCA,B220,protein tyrosine phosphatase, recepto...

Human HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3.
TMPY-01180 CD86 Protein, Human, Recombinant (His)

CD86 antigen,B70,B7.2,B7-2,CD28LG2,LAB72

Human HEK293 Cells
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3.
TMPJ-01099 IL-15RA Protein, Human, Recombinant (hFc, Human Cells)

interleukin-15 receptor subunit α,IL15RA,interleuki...

Human HEK293 Cells
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun...
TMPY-00357 HNT/NTM Protein, Human, Recombinant (His)

HNT,NTRI,IGLON2,neurotrimin

Human HEK293 Cells
HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3.
TMPY-04298 CDCP1 Protein, Human, Recombinant (His)

TRASK,CD318,CUB domain containing protein 1,SIMA1

Human HEK293 Cells
CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3.
TMPY-00480 NCAM1 Protein, Human, Recombinant (His)

neural cell adhesion molecule 1,CD56,MSK39,NCAM

Human HEK293 Cells
NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3.
TMPY-03621 EphB2 Protein, Mouse, Recombinant (hFc)

Tyro5,Erk,Qek5,ETECK,Hek5,Drt,EPH receptor B2,Nuk,P...

Mouse HEK293 Cells
EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3.
TMPY-01268 SMYD3 Protein, Human, Recombinant (GST)

SET and MYND domain containing 3,ZMYND1,KMT3

Human Baculovirus Insect Cells
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It is expressed in skeletal muscles and testis. It is overexpressed in a majority of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). SMYD3 plays an important role in transcriptional reg...
TMPY-03149 CDCP1 Protein, Human, Recombinant (mFc)

TRASK,SIMA135,CD318,CUB domain containing ...

Human HEK293 Cells
CDCP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 61.4 kDa and the accession number is Q9H5V8-3.
TMPY-04386 EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)

PCBC,CAPB,Hek5,EK5,EPHT3,EPH receptor B2,T...

Human Baculovirus Insect Cells
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3.
TMPK-00447 CD45 Protein, Human, Recombinant (aa 26-577, hFc)

CD45,CD45R,LCA,PTPRC,L-CA,T200,B220,GP180,LY5,EC 3....

Human HEK293 Cells
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (aa 26-577...
TMPJ-01288 KLF6 Protein, Human, Recombinant

CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige...

Human E. coli
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul...
TMPY-00276 PLGF/PGF Protein, Human, Recombinant (mFc)

placental growth factor,D12S1900,PLGF,SHGC-10760,PGFL,PlGF-2

Human HEK293 Cells
PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3.
TMPY-04015 COL9A1 Protein, Human, Recombinant (mFc)

DJ149L1.1.2,STL4,collagen, type IX, alpha 1,MED,EDM6,collage...

Human HEK293 Cells
COL9A1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 59.2 kDa and the accession number is P20849-3.
TMPY-06411 GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated

CD357,GITR-D,tumor necrosis factor receptor

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.79 kDa and the accession number is Q9Y5U5-3.
TMPY-05514 RANK/TNFRSF11A Protein, Human, Recombinant (mFc)

OFE,RANK,OPTB7,FEO,tumor necrosis factor receptor s...

Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9Y6Q6-3.
TMPY-03960 COL9A1 Protein, Human, Recombinant (His)

EDM6,collagen, type IX, α1,STL4,collagen, type IX, alpha 1,M...

Human HEK293 Cells
COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is P20849-3.
TMPK-00398 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)

Fibroblast growth factor receptor 2,CD3

Human HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPK-00401 FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD...

Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
TMPJ-00391 FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)

FGF R2b,KGFR,BFR-1,FGFR2 β,FGFR2b,FGFR2,FGFR2 beta,CD3

Human HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.
TMPY-04216 EphB2 Protein, Mouse, Recombinant (His)

Drt,Nuk,Qek5,Tyro5,Prkm5,Sek3,ETECK,Cek5,Hek5,EPH <...

Mouse HEK293 Cells
EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is P54763-3.
TMPY-00715 CD84 Protein, Human, Recombinant (His)

LY9B,mCD84,CD84 molecule,hCD84,SLAMF5

Human HEK293 Cells
CD84 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9UIB8-3.
TMPY-03883 CD47 Protein, Human, Recombinant (hFc)

OA3,CD47 molecule,IAP,MER6

Human HEK293 Cells
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is Q08722-3.
TMPY-02573 IL-17RC Protein, Human, Recombinant (aa 1-454, His)

IL17RL,interleukin 17 receptor C,IL17-RL,UNQ6118/PR...

Human Baculovirus Insect Cells
IL-17RC Protein, Human, Recombinant (aa 1-454, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.6 kDa and the accession number is Q8NAC3-3.
TMPY-01656 VEGF183 Protein, Human, Recombinant

血管内皮生长因子,VEGF165,VPF,VEGF,vascular endothelial growth factor...

Human Baculovirus Insect Cells
VEGF183 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 21 kDa and the accession number is P15692-3.
TMPY-03969 SUSD4 Protein, Human, Recombinant (mFc)

sushi domain containing 4,PRO222

Human HEK293 Cells
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and testis but not other tissues. In brains, SUSD4 is highly expressed in the white matter on oligodendrocytes/axons, and in eyes, it is exclusively expressed on the photoreceptor outer segments. In in vitro complement assays, SUSD4 augments the alternative but not the classical path...
TMPJ-00465 PTP1C Protein, Human, Recombinant (His)

HCP,Hematopoietic Cell Protein-Tyrosine Phosphatase,SH-PTP1,...

Human E. coli
Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against inter...
TMPY-01692 NETO1 Protein, Human, Recombinant (His)

neuropilin (NRP) and tolloid (TLL)-like 1,BCTL1,BTCL1

Human HEK293 Cells
Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDARs in the postsynaptic density. The N-methyl-D-aspartate receptor (NMDAR), a major excitatory ligand-gated ion channel in the central nervous system (CNS), is a principal mediator of synaptic plasticity. Both NETO1 and NETO2 share an identical and unique domain structure thus repr...
TMPY-03705 VEGF164 Protein, Canine, Recombinant

血管内皮生长因子,vascular endothelial growth factor A

Canine HEK293 Cells
VEGF164 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9MYV3-3.
TMPY-05590 NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated

NCAM,MSK39,CD56,neural cell adhesion molecule 1

Human HEK293 Cells
NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 67.9 kDa and the accession number is P13591-3.
TMPY-04157 RANK/TNFRSF11A Protein, Human, Recombinant (His)

ODFR,OFE,CD265,PDB2,RANK,tumor necrosis factor receptor<...

Human HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q9Y6Q6-3.
TMPK-00399 FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated

Keratinocyte growth factor receptor,K-sam,BEK,FGFR2...

Human HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
TMPK-00729 Siglec-6 Protein, Human, Recombinant (His & Avi)

SIGLEC6,OBBP1,CD327,CD33L1,CD...

Human HEK293 Cells
Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains.Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
TMPK-00400 FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated

Fibroblast growth factor receptor 2,KGFR,FGFR-2,KSA...

Human HEK293 Cells
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.3 kDa and the accession number is P21802-3.
TMPJ-00390 FGFR2IIIb Protein, Human, Recombinant (hFc)

FGFR2,FGFR2 beta,FGFR2 β,FGFR2IIIb,KGFR,FGF R2b,BFR-1,FGFR2b...

Human HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession number is P21802-3.
TMPY-05246 CD86 Protein, Human, Recombinant (His), Biotinylated

CD28LG2,B70,B7.2,LAB72,CD86 antigen,B7-2

Human HEK293 Cells
CD86 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P42081-3.
TMPY-05602 GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated

AITR,GITR,tumor necrosis factor receptor superfamil...

Human HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 43.1 kDa and the accession number is Q9Y5U5-3.
TMPY-03435 NCKIPSD Protein, Human, Recombinant (GST)

NCK interacting protein with SH3 domain,WASLBP,SPIN...

Human E. coli
NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. NCKIPSD also plays an important role in stress fiber formation. NCKIPSD gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding d...
TMPY-05383 NKp30/NCR3 Protein, Human, Recombinant (hFc)

DAAP-90L16.3,natural cytotoxicity triggering re...

Human HEK293 Cells
NKp30/NCR3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is O14931-3.
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重组蛋白

FGF-8b Protein, Human, Recombinant
Cat.No: TMPY-06986
Species: Human
Expression System: E. coli
Mesothelin Protein, Human, Recombinant
Cat.No: TMPY-00132
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant (aa 1-139, His)
Cat.No: TMPY-04935
Species: Human
Expression System: HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03763
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant, Biotinylated
Cat.No: TMPY-05191
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His)
Cat.No: TMPY-00072
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant
Cat.No: TMPY-04683
Species: Human
Expression System: HEK293 Cells
Neuropilin-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00892
Species: Human
Expression System: HEK293 Cells
PRSS3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01897
Species: Human
Expression System: HEK293 Cells
Periostin/OSF-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01020
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04142
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Human, Recombinant (aa 26-577, His)
Cat.No: TMPY-05748
Species: Human
Expression System: HEK293 Cells
CD86 Protein, Human, Recombinant (His)
Cat.No: TMPY-01180
Species: Human
Expression System: HEK293 Cells
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
Cat.No: TMPJ-01099
Species: Human
Expression System: HEK293 Cells
HNT/NTM Protein, Human, Recombinant (His)
Cat.No: TMPY-00357
Species: Human
Expression System: HEK293 Cells
CDCP1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04298
Species: Human
Expression System: HEK293 Cells
NCAM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00480
Species: Human
Expression System: HEK293 Cells
EphB2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03621
Species: Mouse
Expression System: HEK293 Cells
SMYD3 Protein, Human, Recombinant (GST)
Cat.No: TMPY-01268
Species: Human
Expression System: Baculovirus Insect Cells
CDCP1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03149
Species: Human
Expression System: HEK293 Cells
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)
Cat.No: TMPY-04386
Species: Human
Expression System: Baculovirus Insect Cells
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
Cat.No: TMPK-00447
Species: Human
Expression System: HEK293 Cells
KLF6 Protein, Human, Recombinant
Cat.No: TMPJ-01288
Species: Human
Expression System: E. coli
PLGF/PGF Protein, Human, Recombinant (mFc)
Cat.No: TMPY-00276
Species: Human
Expression System: HEK293 Cells
COL9A1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04015
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06411
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05514
Species: Human
Expression System: HEK293 Cells
COL9A1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03960
Species: Human
Expression System: HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
Cat.No: TMPK-00398
Species: Human
Expression System: HEK293 Cells
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00401
Species: Human
Expression System: HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
Cat.No: TMPJ-00391
Species: Human
Expression System: HEK293 Cells
EphB2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04216
Species: Mouse
Expression System: HEK293 Cells
CD84 Protein, Human, Recombinant (His)
Cat.No: TMPY-00715
Species: Human
Expression System: HEK293 Cells
CD47 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03883
Species: Human
Expression System: HEK293 Cells
IL-17RC Protein, Human, Recombinant (aa 1-454, His)
Cat.No: TMPY-02573
Species: Human
Expression System: Baculovirus Insect Cells
VEGF183 Protein, Human, Recombinant
Cat.No: TMPY-01656
Species: Human
Expression System: Baculovirus Insect Cells
SUSD4 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03969
Species: Human
Expression System: HEK293 Cells
PTP1C Protein, Human, Recombinant (His)
Cat.No: TMPJ-00465
Species: Human
Expression System: E. coli
NETO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01692
Species: Human
Expression System: HEK293 Cells
VEGF164 Protein, Canine, Recombinant
Cat.No: TMPY-03705
Species: Canine
Expression System: HEK293 Cells
NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05590
Species: Human
Expression System: HEK293 Cells
RANK/TNFRSF11A Protein, Human, Recombinant (His)
Cat.No: TMPY-04157
Species: Human
Expression System: HEK293 Cells
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
Cat.No: TMPK-00399
Species: Human
Expression System: HEK293 Cells
Siglec-6 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00729
Species: Human
Expression System: HEK293 Cells
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00400
Species: Human
Expression System: HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00390
Species: Human
Expression System: HEK293 Cells
CD86 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05246
Species: Human
Expression System: HEK293 Cells
GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05602
Species: Human
Expression System: HEK293 Cells
NCKIPSD Protein, Human, Recombinant (GST)
Cat.No: TMPY-03435
Species: Human
Expression System: E. coli
NKp30/NCR3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05383
Species: Human
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
TMIH-0314 Lurasidone-d8 HCl

Lurasidone-d8 HCl 是 Lurasidone HCl 的氘代化合物。Lurasidone HCl 的 CAS 号为 367514-88-3。Lurasidone hydrochloride 是多巴胺 D2和5-HT7的拮抗剂,IC50值分别为 1.68 和 0.495 nM,用于治疗精神分裂症和双相情感障碍。它也是5-HT1A受体的部分激动剂,IC50值为 6.75 nM。
TMIJ-0499 Granisetron-d3

Granisetron-d3 是 Granisetron 的氘代化合物。Granisetron 的 CAS 号为 109889-09-0。
T70960 Maprotiline-d3 hydrochloride

Maprotiline-d3 is intended for use as an internal standard for the quantification of maprotiline by GC- or LC-MS. Maprotiline is a tricyclic antidepressant. It binds to the norepinephrine transporter (NET) and is selective for NET over the serotonin and dopamine transporters. Maprotiline also binds to the serotonin (5-HT) receptor subtype 5-HT2A, as well as histamine H1, muscarinic acetylcholine, α1-adrenergic, and dopamine D2 receptors. In vivo, maprotiline inhibits norepinephrine reuptake in r...

同位素标记化合物

Lurasidone-d8 HCl
Cat.No: TMIH-0314
Synonym:
Target:
Granisetron-d3
Cat.No: TMIJ-0499
Synonym:
Target:
Maprotiline-d3 hydrochloride
Cat.No: T70960
Synonym:
Target:
TargetMol Loading
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