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Search Results for " pregnancy "
Targets Recommended: Others

30

抑制剂 & 化合物

10

天然产物

41

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3

同位素标记化合物

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Cat. No. Product Name Target Signaling Pathways
T0023 Valethamate bromide

Ediposin,Epidozin,戊沙溴铵,Epidosin,Resitan

Others Others
Valethamate bromide (Resitan) 是快速作用的抗胆碱能解痉和肌萎缩剂,是一种酯,能够改善宫颈扩张加速分娩。
T8132 Iron sucrose

Iron saccharate,蔗糖铁,Sucroferric oxyhydroxide

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
Iron sucrose (Sucroferric oxyhydroxide) 是一种静脉注射铁制剂,也是一种促氧化剂,可用于研究缺铁性贫血。
T20570 Labetalol

Apo-Labetalol,Albetol,Trandate,Dilevalol,拉贝洛尔,Normodyne

Adrenergic Receptor GPCR/G Protein; Neuroscience
Labetalol (Apo-Labetalol) 是一种抗高血压药物,可用于心血管疾病的研究,如妊娠期高血压。它是一种口服具有活性的选择性 α1- 和非选择性 β-肾上腺素能受体 (adrenergic receptor) 竞争性拮抗剂。
T22285 Carboprost

15(S)-15-Methyl Prostaglandin F2α,15-Methyl-PGF2α,卡前列素

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Carboprost (15(S)-15-Methyl Prostaglandin F2α) 是一种前列腺素 F2α 的代谢稳定的合成类似物。它能够刺激子宫收缩并引起流产,可用于子宫收缩乏力引起的产后出血,以及在妊娠中期终止妊娠。
T31213 Dazmegrel

UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485

PPAR DNA Damage/DNA Repair; Metabolism
Dazmegrel (UK 38,485) 是一种强效特异性血栓素 A2(TXA2)合成酶抑制剂,可用于预防正常妊娠中全血小板聚集增加。
T61864 Melengestrol acetate

Progesterone Receptor Others
Melengestrol acetate 是孕酮的衍生物,充当皮质类固醇激素。 Melengestrol acetate 可以促进月经活动和妊娠维持的子宫内膜增殖延迟。
T1110 Meclizine dihydrochloride

Meclozine dihydrochloride,NSC28728,Meclizine 2HCl,盐酸美克洛嗪

Apoptosis; Histamine Receptor Apoptosis; GPCR/G Protein; Immunology/Inflammation; Neuroscience
Meclizine dihydrochloride (NSC28728) 是一种组胺 H1 拮抗剂,用于治疗妊娠期间的晕动病、眩晕和恶心以及放射病。它是小鼠组成型雄甾烷受体激动剂,是人 CAR 的反向激动剂。它可透过血脑屏障,可用于多聚谷氨酰胺毒性障碍方面的研究。
T24415 Lotrifen

Privaprol,L-12717,DL 717-IT,L 12717,L12717,Canocenta

Others Others
Lotrifen (Privaprol) 是一种非激素抗生育药物,Lotrifen 引起妊娠停止和复旧。在胚泡着床后,它直接作用于受精卵,受精卵经历一个缓慢而逐渐的退化过程,并以受精卵的再吸收或排出而结束。
T4616 Metoclopramide

甲氧氯普胺,胃复安,5-Chloro-2-methoxyprocainamide

Dopamine Receptor; 5-HT Receptor GPCR/G Protein; Neuroscience
Metoclopramide (5-Chloro-2-methoxyprocainamide) 是5-HT3和多巴胺D2受体拮抗剂,IC50值分别为 308 和 483 nM,可用于恶心呕吐、胃食管反流和胃轻瘫的研究。
T34165 Prostalene

RS 9390,RS9390,RS-9390,Synchrocept

Others Others
Prostalene is a prostaglandin F(2)alpha analogue used in pregnancy.
T27108 Cymipristone

ZXH951,ZXH 951,ZXH-951

Others Others
Cymipristone, a progesterone receptor antagonist, is used potentially for termination of intrauterine pregnancy.
T31756 Fe-Cap folic

Others Others
Fe-Cap folic is an encapsulated dosage for use as an iron supplement in pregnancy.
T29486 7-Methotrexate

7-Mtx

Others Others
7-Methotrexate is used as a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and medical abortions.
T29391 3'-Chloromethotrexate

NSC 29631,NSC29631,SKI 23338,NSC-29631,AI3-50533

Others Others
3'-Chloromethotrexate is a chemotherapy agent and immune system suppressant. It can be used to treat cancer, autoimmune diseases, ectopic pregnancy, and medical abortions.
T33326 Methotrexate-alpha glutamate

Meapa-glu-glu

Others Others
Methotrexate-alpha glutamate is a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and medical abortions.
T34302 Retroprogesterone

Others Others
Retroprogesterone, a progestin, may be used for menstrual irregularities in adolescence, for the maintenance of threatened pregnancy, and possibly as an ovulation stimulant.
T31851 Formiminoglutamic acid

NSC-334078,NSC334078,NSC 334078

Others Others
Formiminoglutamic acid is used to indicate folic acid deficiency and megaloblastic anemia of pregnancy with the measurement in the urine after oral administration of histidine.
T20855 Gemeprost

SC-37681,SC 37681,Carprost,Gemeprostum,Cervagem,Preglandin

Others Others
Gemeprost, an analog of prostaglandin E1, is used for the treatment of obstetric bleeding. It is used to terminate pregnancy up to 24 weeks gestation together with mifepristone.
T36829 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2

Others Others
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This prostaglandin mixture is ineffective on monkeys in their third trimes...
T70570 Erlosiban

Others Others
Erlosiban, also known as OBE001, is a novel, orally active nonpeptide oxytocin receptor antagonist under development for the treatment of preterm labor and improvement in embryo implantation and pregnancy rate in assisted reproductive technology (ART).
T37327 Prostaglandin F2α 1,15-lactone

Prostaglandin F2α 1,15-lactone

Others Others
PGF2α 1,15-lactone is a lipid-soluble internal ester of PGF2α. Hydrolysis of the lactone readily produces free PGF2α in plasma. In rhesus monkeys, a total dose of 15 mg of PGF2α 1,15-lactone terminates early pregnancy, whereas PGF2α is ineffective.
T73761 Estriol 16α-(β-D-glucuronide)

Others Others
Estriol 16α-(β-D-glucuronide) 是存在于尿中的内源代谢物,可用于研究妊娠。
T84618 tetranor-PGFM

tetranor-Prostaglandin F Metabolite

Others Others
Tetranor-PGFM, the principal urinary metabolite of PGF2α, is excreted at rates of 7-13 µg per day in healthy females and 11-59 µg per 24 hours in healthy males. During pregnancy, female urinary levels of tetranor-PGFM increase 2 to 5-fold, returning to normal shortly after childbirth.
T74179 1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine

Others Others
1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine,一种血液中的内源性代谢物,主要用于妊娠和败血症的研究。
T37230 (+)-5-trans Cloprostenol

Others Others
Cloprostenol is a synthetic derivative of prostaglandin F2α that is used in veterinary medicine as a luteolytic agent for the induction of estrus and in the treatment of reproductive disorders in cattle, swine, and horses. (+)-5-trans Cloprostenol is a minor impurity produced in the synthesis of (+)-cloprostenol. The (+)-5-trans isomer is 20-fold less active than the 5-cis form in terminating pregnancy in the hamster.
T37122 1,2-Dilinoleoyl-sn-glycerol

Others Others
1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (18:2) side chains attached at both the sn-1 and sn-2 positions. It has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes. 1,2-Dilinoleoyl-sn-glycerol is upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy.
T28685 SB236057

SB-236057,SB 236057

Others Others
SB236057 is a potent and selective inverse agonist for the 5-HT receptor, acting especially at 5-HT autoreceptors on nerve terminals. It produces a rapid increase in 5-HT levels in the brain. SB236057 also acts as a potent teratogen, producing severe musc
T64294 Succinic acid sodium

Others Others
Succinic acid sodium 是一种口服具有活力的抗焦虑剂。Succinic acid sodium 能够下调 KCNMB1 (钾通道亚基 β1) 和TET1(10-11 易位 1) 的表达。Succinic acid sodium 可抑制体内的结肠上皮细胞的增殖。Succinic acid sodium 能够用于研究妊娠期高血压。
T37231 (+)-Cloprostenol methyl ester

Others Others
(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. It is 200 times and 100 times more potent than PGF2α in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with PGF2α. Cloprostenol is also used in veterinary medicine as a luteolytic agent for the induction of estrus and the treatment of reproductive disorders in cattle, swine, and horses. (+)-Cloprosteno...
T73734 Acetoacetic acid

Others Others
Acetoacetic acid是一种存在于脑脊液中的内源代谢物,主要应用于脑膜炎、妊娠、3-羟基-3-甲基戊二酰辅酶A裂解酶缺乏症、子痫前期/子痫、2型糖尿病、1型葡萄糖转运蛋白缺乏综合征及琥珀酰辅酶A:3-氧酸辅酶A转移酶缺乏症的研究中。

化合物

Valethamate bromide
Cat.No: T0023
Synonym: Ediposin,Epidozin,戊沙溴铵,Epidosin,Resitan
Target: Others
Iron sucrose
Cat.No: T8132
Synonym: Iron saccharate,蔗糖铁,Sucroferric oxyhydroxide
Target: Reactive Oxygen Species
Labetalol
Cat.No: T20570
Synonym: Apo-Labetalol,Albetol,Trandate,Dilevalol,拉贝洛尔,Normodyne
Target: Adrenergic Receptor
Carboprost
Cat.No: T22285
Synonym: 15(S)-15-Methyl Prostaglandin F2α,15-Methyl-PGF2α,卡前列素
Target: Prostaglandin Receptor
Dazmegrel
Cat.No: T31213
Synonym: UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485
Target: PPAR
Melengestrol acetate
Cat.No: T61864
Synonym:
Target: Progesterone Receptor
Meclizine dihydrochloride
Cat.No: T1110
Synonym: Meclozine dihydrochloride,NSC28728,Meclizine 2HCl,盐酸美克洛嗪
Target: Apoptosis, Histamine Receptor
Lotrifen
Cat.No: T24415
Synonym: Privaprol,L-12717,DL 717-IT,L 12717,L12717,Canocenta
Target: Others
Metoclopramide
Cat.No: T4616
Synonym: 甲氧氯普胺,胃复安,5-Chloro-2-methoxyprocainamide
Target: Dopamine Receptor, 5-HT Receptor
Prostalene
Cat.No: T34165
Synonym: RS 9390,RS9390,RS-9390,Synchrocept
Target: Others
Cymipristone
Cat.No: T27108
Synonym: ZXH951,ZXH 951,ZXH-951
Target: Others
Fe-Cap folic
Cat.No: T31756
Synonym:
Target: Others
7-Methotrexate
Cat.No: T29486
Synonym: 7-Mtx
Target: Others
3'-Chloromethotrexate
Cat.No: T29391
Synonym: NSC 29631,NSC29631,SKI 23338,NSC-29631,AI3-50533
Target: Others
Methotrexate-alpha glutamate
Cat.No: T33326
Synonym: Meapa-glu-glu
Target: Others
Retroprogesterone
Cat.No: T34302
Synonym:
Target: Others
Formiminoglutamic acid
Cat.No: T31851
Synonym: NSC-334078,NSC334078,NSC 334078
Target: Others
Gemeprost
Cat.No: T20855
Synonym: SC-37681,SC 37681,Carprost,Gemeprostum,Cervagem,Preglandin
Target: Others
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
Cat.No: T36829
Synonym: 9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
Target: Others
Erlosiban
Cat.No: T70570
Synonym:
Target: Others
Prostaglandin F2α 1,15-lactone
Cat.No: T37327
Synonym: Prostaglandin F2α 1,15-lactone
Target: Others
Estriol 16α-(β-D-glucuronide)
Cat.No: T73761
Synonym:
Target: Others
tetranor-PGFM
Cat.No: T84618
Synonym: tetranor-Prostaglandin F Metabolite
Target: Others
1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine
Cat.No: T74179
Synonym:
Target: Others
(+)-5-trans Cloprostenol
Cat.No: T37230
Synonym:
Target: Others
1,2-Dilinoleoyl-sn-glycerol
Cat.No: T37122
Synonym:
Target: Others
SB236057
Cat.No: T28685
Synonym: SB-236057,SB 236057
Target: Others
Succinic acid sodium
Cat.No: T64294
Synonym:
Target: Others
(+)-Cloprostenol methyl ester
Cat.No: T37231
Synonym:
Target: Others
Acetoacetic acid
Cat.No: T73734
Synonym:
Target: Others
Cat. No. Product Name Target Signaling Pathways
T3894 Polyphyllin II

重楼皂苷 II,Chonglou Saponin II

Apoptosis; Others Apoptosis; Others
Polyphyllin II (Chonglou Saponin II) 是重楼中重要的一种皂苷,具有止血、祛痰、抑菌、抗细胞毒和抗孕杀精作用。它通过 caspases 激活和细胞周期停滞诱导细胞凋亡。
T6S2315 Polyphyllin VI

Apoptosis; Antibacterial; Pyroptosis Apoptosis; Immunology/Inflammation; Microbiology/Virology
Polyphyllin VI 是一种活性皂甙,诱导 G2/M 细胞周期停滞并引发细胞凋亡,具有抗癌活性。它通过诱导非小细胞肺癌中的 ROS/NF-κB/NLRP3/GSDMD 信号轴来诱导 caspase-1 介导的细胞焦亡。
T3O2784 Vitamin B6

维生素B6

Others Others
Vitamin B6 是人体某些辅酶的成分,参与多种代谢反应,特别是与氨基酸代谢有关。维生素B6在防治妊娠和放射病呕吐中的临床应用。
T1571 Estriol

NSC-12169,Oestriol,雌三醇

Estrogen Receptor/ERR; Estrogen/progestogen Receptor; MRP; Endogenous Metabolite Endocrinology/Hormones; Immunology/Inflammation; Metabolism
Estriol (Oestriol) 是G 蛋白偶联雌激素受体拮抗剂,能够作用于雌激素受体阴性乳腺癌细胞。
T0478 Progesterone

孕酮,Pregn-4-ene-3,20-dione

Estrogen/progestogen Receptor; Progesterone Receptor; Opioid Receptor; Endogenous Metabolite Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience; Others
Progesterone (Pregn-4-ene-3,20-dione) 是类固醇激素,能够调节月经周期。
T1429 17α-Hydroxyprogesterone

Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮

Estrogen/progestogen Receptor; Progesterone Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism; Others
17α-Hydroxyprogesterone (17-OHP) 是一种内源性孕激素,其他类固醇激素(包括糖皮质激素,雌激素,和雄激素)生物合成的化学中间体。
T1688 Pregnanediol

5Beta-Pregnane-3Alpha,20alpha-Diol,孕甾二醇,Pregnandiol,孕二醇

Estrogen/progestogen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) 是一种黄体酮的主要代谢物 (metabolite),能够通过尿液排出。它提供了一种间接测定体内孕激素水平的方法。
T4723 D-Tagatose

塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos

Others; Endogenous Metabolite Metabolism; Others
D-Tagatose (D-(-)-Tagatose) 是自然界中发现的一种罕见的单糖,具有益生元特性。它是研究II 型糖尿病的潜在抗糖尿病药物,也是帮助提升结肠有益细菌、预防结肠癌和抑制胆固醇的益生元。它是蔗糖的替代品,也是口香糖、果汁和饮料等食品中的低热量甜味剂。
T37499 Estriol 3-glucuronide

Others Others
Estriol-3-glucuronide, a natural compound found in urine, is also present in amniotic fluid during normal pregnancy [1][2].
TN5961 Gardenolic acid B

Gardenolic acid B shows promising hepatoprotective effects on nitrofurantoin-induced cytotoxicity in human liver-derived Hep G2 cells. Gardenolic acid B shows significant effects on terminating early pregnancy in rats.

天然产物

Polyphyllin II
Cat.No: T3894
Synonym: 重楼皂苷 II,Chonglou Saponin II
Target: Apoptosis, Others
Polyphyllin VI
Cat.No: T6S2315
Synonym:
Target: Apoptosis, Antibacterial, Pyroptosis
Vitamin B6
Cat.No: T3O2784
Synonym: 维生素B6
Target: Others
Estriol
Cat.No: T1571
Synonym: NSC-12169,Oestriol,雌三醇
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, MRP, Endogenous Metabolite
Progesterone
Cat.No: T0478
Synonym: 孕酮,Pregn-4-ene-3,20-dione
Target: Estrogen/progestogen Receptor, Progesterone Receptor, Opioid Receptor, Endogenous Metabolite
17α-Hydroxyprogesterone
Cat.No: T1429
Synonym: Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮
Target: Estrogen/progestogen Receptor, Progesterone Receptor, Endogenous Metabolite
Pregnanediol
Cat.No: T1688
Synonym: 5Beta-Pregnane-3Alpha,20alpha-Diol,孕甾二醇,Pregnandiol,孕二醇
Target: Estrogen/progestogen Receptor, Endogenous Metabolite
D-Tagatose
Cat.No: T4723
Synonym: 塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos
Target: Others, Endogenous Metabolite
Estriol 3-glucuronide
Cat.No: T37499
Synonym:
Target: Others
Gardenolic acid B
Cat.No: TN5961
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPH-00296 Pregnancy-associated protein bPAP Protein, Bovine, Recombinant (His & Myc)

Pregnancy-associated protein bPAP

Bovine E. coli
Pregnancy-associated protein bPAP Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.3 kDa and the accession number is P84291.
TMPH-00294 PAG-1 Protein, Bovine, Recombinant (His & SUMOstar)

Pregnancy-associated glycoprotein 1,Pregnancy

Bovine P. pastoris (Yeast)
Appears to be proteolytically inactive. PAG-1 Protein, Bovine, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 49.8 kDa and the accession number is Q29432.
TMPH-00293 PAG-1 Protein, Bovine, Recombinant (His)

Pregnancy-specific protein B,Pregnancy-ass...

Bovine E. coli
Appears to be proteolytically inactive. PAG-1 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.7 kDa and the accession number is Q29432.
TMPJ-01375 HSPB7 Protein, Human, Recombinant (His)

Pregnancy specific β-1-glycoprotein 2,PSG2,PSBG2,

Human E. coli
HSPB7 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 20-25 KDa and the accession number is Q9UBY9.
TMPJ-00838 PSG2 Protein, Human, Recombinant (His)

pregnancy-specific β-1-glycoprotein 2,Pregnancy...

Human HEK293 Cells
PSG2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 43 KDa and the accession number is P11465.
TMPH-00295 PAG-2 Protein, Bovine, Recombinant (His)

PAG2,Pregnancy-associated glycoprotein 2

Bovine E. coli
PAG2 or a processed derivative of this molecule might represent a factor that binds the LH receptor. PAG-2 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 43.6 kDa and the accession number is Q28057.
TMPJ-00522 PSG9 Protein, Human, Recombinant (His)

PS-β-G-11,PS-β-G-9,PS-β-B,Pregnancy-specific β-1 gl...

Human HEK293 Cells
Pregnancy-specific beta-1-glycoprotein 9(PSG9) is a secreted protein and contains 3 Ig-like C2-type (immunoglobulin-like) domains, 1 Ig-like V-type (immunoglobulin-like) domain. It is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in ...
TMPH-01987 PSG7 Protein, Human, Recombinant (His)

PSG7,Pregnancy-specific beta-1-glycoprotein 7

Human E. coli
PSG7 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-01135 PSG3 Protein, Human, Recombinant (His)

PS-Beta-G-3,Pregnancy-specific β-1-glycoprotein 3,C...

Human HEK293 Cells
Pregnancy-specific beta-1-glycoprotein 3 is also known as Carcinoembryonic Antigen SG5,Pregnancy-Specific Glycoprotein 3 ,PS-Beta-G-3, PSBG-3.It belongs to the immunoglobulin superfamily. CEA family.It synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular Cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, Members of the CEA family consist o...
TMPH-01986 PSG7 Protein, Human, Recombinant (His & Myc)

Pregnancy-specific beta-1-glycoprotein 7,PSG7

Human HEK293 Cells
PSG7 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.
TMPJ-00506 PSG5 Protein, Human, Recombinant (His)

PSBG-5,FL-NCA-3,Pregnancy-specific β-1-glycoprotein...

Human HEK293 Cells
Pregnancy-specific beta-1-glycoprotein 5, is a secreted protein which belongs to the immunoglobulin superfamily, CEA family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain.
TMPY-02891 PSG6 Protein, Human, Recombinant (His)

PSG12,PSG6,PSBG-6,pregnancy specific β-1-glycoprote...

Human Baculovirus Insect Cells
PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived fr...
TMPJ-00476 BMPG Protein, Human, Recombinant (His)

Bone Marrow Proteoglycan,PRG2,Proteoglycan 2,Eosinophil Gran...

Human HEK293 Cells
Bone Marrow Proteoglycan (BMPG) is a secreted protein that contains one C-type lectin domain. BMPG is the predominant constituent of the crystalline core of the eosinophil granule. BMPG is highly expressed in placenta and pregnancy serum. BMPG may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin. BMPG induces non-cytolytic histamine release from human basophils. In addition, BMPG also participated in antiparasitic defense mechanisms and immune hypersensitivity re...
TMPH-01896 PZP Protein, Human, Recombinant (His)

Pregnancy zone protein,C3 and PZP-like alpha-2-macr...

Human E. coli
PZP Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 42.3 kDa and the accession number is P20742.
TMPY-00551 PSG1 Protein, Human, Recombinant (hFc)

PSGIIA,PS-β-C/D,FL-NCA-1/2,PSBG1,PSG95,PS-beta-G-1,pregn...

Human HEK293 Cells
PSG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa and the accession number is P11464-1.
TMPY-00552 PSG1 Protein, Human, Recombinant (His)

PS-β-G-1,PSBG-1,PS-beta-G-1,CD66f,pregnancy specifi...

Human HEK293 Cells
PSG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.9 kDa and the accession number is P11464-1.
TMPH-01402 Glycodelin Protein, Human, Recombinant (His & Myc)

Zona-binding inhibitory factor-1,Pregnancy-associat...

Human HEK293 Cells
Glycodelin Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 23.9 kDa and the accession number is P09466.
TMPH-01401 Glycodelin Protein, Human, Recombinant (His)

Placental protein 14,Progesterone-associated endometrial pro...

Human E. coli
Glycodelin Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 22.4 kDa and the accession number is P09466.
TMPY-00539 GSTA1 Protein, Human, Recombinant (His)

glutathione S-transferase alpha 1,GTH1,GST2,glutathione S-tr...

Human HEK293 Cells
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adeno...
TMPY-03962 AFM Protein, Human, Recombinant (His)

afamin,ALBA,ALB2,ALF

Human HEK293 Cells
Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determination. Afamin, a human plasma glycoprotein and putative transporter of hydrophobic molecules, has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. The 2.1-Å crystal structure of...
TMPK-00030 LAIR2 Protein, Human, Recombinant (Avi & His)

CD306,LAIR-2,LAIR2,MGC71634,XXbac-BCX535A19.6

Human HEK293 Cells
The leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) shows increased expression during pregnancy and its reduced expression is associated with pregnancy complications. Although LAIR2 was expressed in the human placenta villus and decidua in the first trimester of pregnancy, it was not expressed in mouse tissues. Knockdown of LAIR2 markedly improved cell viability and inhibited the invasive ability of HTR8/SVneo cells.
TMPJ-01379 TAC3 Protein, Human, Recombinant (His)

Neurokinin-B,Tachykinin-3,UNQ585/PRO1155,NKNB,ZNEUROK1,TAC3,...

Human E. coli
Tachykinin 3 (TAC3) is a secreted protein that belongs to the Tachykinin family. Tachykinins are active peptides that excite neurons and evoke behavioral responses; they are potent vasodilators and secretagogues, and contract many smooth muscles in pregnancy. TAC3 is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. It is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension ...
TMPH-02493 ADAMDEC1 Protein, Mouse, Recombinant (His)

A disintegrin and metalloproteinase domain-like protein decy...

Mouse E. coli
May play an important role in the control of the immune response and during pregnancy. ADAMDEC1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.9 kDa and the accession number is Q9R0X2.
TMPJ-00906 CRHBP Protein, Human, Recombinant (His)

CRF-BP,CRF-Binding Protein,Corticotropin-Releasing Factor-Bi...

Human HEK293 Cells
Corticotropin-Releasing Factor-Binding Protein (CRHBP) is a 37 kDa secreted glycoprotein that binds both CRH and urocortin in a 42 kDa extracellular complex. The molecule is approximately 300 amino acids in length and demonstrates five intrachain disulfide bonds. Difference between CRHBP from different species exist, human CRHBP is found in plasma while rodent and sheep CRHBP is limited to neuroendocrine tissues. CRHBP may inactivate CRH and may prevent inappropriate pituitary-adrenal stimulatio...
TMPH-01087 CSH2 Protein, Human, Recombinant (GST & His)

Chorionic somatomammotropin hormone 2,Lactogen,Choriomammotr...

Human E. coli
Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. CSH2 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 53.8 kDa and the accession number is P0DML3.
TMPJ-00049 CGB Protein, Human, Recombinant (His)

Chorionic gonadotrophin chain β,CG-β,Chorionic gonadotrophin...

Human HEK293 Cells
Choriogonadotropin subunit beta is also known as CG-beta, Chorionic gonadotrophin chain beta. It is a protein that in humans is encoded by the CGB gene. It belongs to the glycoprotein hormones subunit beta family. Choriogonadotropin subunit beta can stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy.
TMPY-02800 CGB7 Protein, Human, Recombinant (His)

chorionic gonadotropin beta subunit 7,chorionic gonadotropin...

Human Baculovirus Insect Cells
CGB7 (chorionic gonadotropin, beta polypeptide 7) belongs to the glycoprotein hormones subunit beta family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CGB7 gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are...
TMPJ-00665 ADAMDEC1 Protein, Human, Recombinant (His)

a disintegrin and metalloproteinase domain-like protein decy...

Human HEK293 Cells
ADAM DEC1 protein is expressed highly in the small intestine and appendix, moderately in lymph node, mucosal lining of the colon, thymus, spleen and very weakly in the bone marrow. ADAM DEC1 is induced during DC maturation and up-regulated in response to T-cell signals. It may play an important role in the control of the immune response and during pregnancy.
TMPK-00928 VLDLR Protein, Mouse, Recombinant (His)

CHRMQ1,VLDLR,FLJ35024,VLDLRCH,RP11-320E16.1,VLDL-R

Mouse HEK293 Cells
VLDLR cerebellar hypoplasia (VLDLR-CH) is characterized by non-progressive congenital ataxia that is predominantly truncal and results in delayed ambulation, moderate-to-profound intellectual disability, dysarthria, strabismus, and seizures.VLDLR-CH is inherited in an autosomal recessive manner. Carrier testing for at-risk relatives, prenatal testing for a pregnancy at increased risk and preimplantation genetic testing are possible when the pathogenic variants in a family are known.
TMPJ-00987 PLGF/PGF Protein, Mouse, Recombinant (His)

Plgf,PlGF-2,PGFL,PGF,SHGC-10760,D12S1900,Placenta growth fac...

Mouse HEK293 Cells
Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. The protein is a member of the VEGF (vascular endothelial growth factor) sub-family-a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast.
TMPK-00976 AMHRII Protein, Human, Recombinant

MRII,AMHR2,AMH type II receptor,MIS type II receptor,AMHR,AM...

Human HEK293 Cells
The aim of the current study was to explore whether anti-Müllerian hormone receptor II (AMHRII) genetic variants influence the hormonal profile and the ovarian response to standard gonadotropin stimulation of women undergoing medically assisted reproduction. Three hundred in vitro fertilization or intracytoplasmic sperm injection patients constituted the study population, while 300 women with at least one spontaneous pregnancy participated as controls. AMHRII Protein, Human, Recombinant is expre...
TMPK-00977 AMHRII Protein, Human, Recombinant (hFc)

MISR2,AMHR2,AMH type II receptor,AMHR,C14,MIS type II recept...

Human HEK293 Cells
The aim of the current study was to explore whether anti-Müllerian hormone receptor II (AMHRII) genetic variants influence the hormonal profile and the ovarian response to standard gonadotropin stimulation of women undergoing medically assisted reproduction. Three hundred in vitro fertilization or intracytoplasmic sperm injection patients constituted the study population, while 300 women with at least one spontaneous pregnancy participated as controls. AMHRII Protein, Human, Recombinant (hFc) is...
TMPJ-00832 Granzyme D/GZMD Protein, Mouse, Recombinant (His)

Granzyme D,Gzmd

Mouse HEK293 Cells
Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, but the function of granzyme D is unknown. Previous studies reported that granzyme D is developmentally regulated during pregnancy together with granzymes E, F, and G in granulated metrial gland cells and is upregulated by IL-2 and IL-15. Granzyme D was also suggested to have a ro...
TMPY-00540 ANXA5 Protein

annexin A5

The placental anticoagulant protein Annexin A5 (ANXA5) is a multifunctional protein that is highly expressed on the apical surfaces of syncytiotrophoblasts, and plays an important role in haemostatic regulations, maintaining blood fluidity of the placenta. Annexin A5 (ANXA5) is a protein abundantly expressed in normal placenta where it contributes to the healthy outcome of a pregnancy. Lower ANXA5 levels have been observed in M2/ANXA5 haplotype carrying chorion. The association found between the...
TMPY-01826 Relaxin 1/RLN1 Protein, Human, Recombinant (His)

RLXH1,H1RLX,relaxin 1,bA12D24.3.1,H1,RLN1,bA12D24.3.2

Human HEK293 Cells
Relaxin-1, also known as Prorelaxin H1 and RLN1, is a secreted protein that belongs to the insulin family. It is a peptide hormone that was first described in 1926 by Frederick Hisaw. Since its discovery as a reproductive hormone 8 years ago, relaxin has been implicated in a number of pregnancy-related functions involving extracellular matrix (ECM) turnover and collagen degradation. It is now becoming evident that relaxin's ability to reduce matrix synthesis and increase ECM degradation has impo...
TMPH-01297 DDR1 Protein, Human, Recombinant (aa 21-417, His)

EDDR1,MCK-10,Epithelial discoidin domain-containing receptor...

Human HEK293 Cells
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell...
TMPJ-01432 CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated

mucin 16, cell surface associated,CA-125,CA125 ovarian cance...

Human HEK293 Cells
MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. MUC16 is over-expressed by tumor cells including ovarian and mesothelial cancers. The transmembrane form can adhere to mesothelin in the peritoneum, facilitating metastasis of ovarian cancer to the peritoneal cavity. MUC16 also binds galectin-1 on immune cells and enhances its expression on tumor cells. MUC...
TMPJ-01418 CSF1R Protein, Cynomolgus, Recombinant (hFc)

M-CSF-R,CSF1R,CSF-1-R,CSF-1 receptor,CSF-1R,Macrophage colon...

Cynomolgus HEK293 Cells
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. CSF1R is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. CSF1 and its receptor (CSF1R, product of ...
TMPJ-01419 CSF1R Protein, Cynomolgus, Recombinant (His)

CSF-1-R,CSF-1 receptor,Proto-oncogene c-Fms,M-CSF-R,Macropha...

Cynomolgus HEK293 Cells
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. CSF1R is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. CSF1 and its receptor (CSF1R, product of ...
TMPJ-00054 PLGF-2 Protein, Human, Recombinant (His)

PlGF-2,PlGF2,PlGF,PGF,PGFL

Human HEK293 Cells
Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. Alternate splicing results in at least three human mature PlGF forms containing 131 (PlGF‑1), 152 (PlGF‑2), and 203 (PlGF‑3) amino acids (aa) respectively. PlGF is mainly found as a variably glycosylated, secreted, 55 ‑ 60 kDa disulfide linked homodimer.The protein is a member of the VEGF (vascular endothelial growth factor) sub-family-a key ...
TMPY-00585 Annexin A8 Protein, Human, Recombinant (His)

ANX8,annexin A8

Human E. coli
We have previously shown that Annexin A8 (ANXA8) is strongly associated with the basal-like subgroup of breast cancers, including BRCA1-associated breast cancers, and poor prognosis; while in the mouse mammary gland AnxA8 mRNA is expressed in low-proliferative isolated pubertal mouse mammary ductal epithelium and after enforced involution, but not in isolated highly proliferative terminal end buds (TEB) or during pregnancy. ANXA8 as a potential mediator of quiescence in the normal mouse mammary ...

重组蛋白

Pregnancy-associated protein bPAP Protein, Bovine, Recombinant (His & Myc)
Cat.No: TMPH-00296
Species: Bovine
Expression System: E. coli
PAG-1 Protein, Bovine, Recombinant (His & SUMOstar)
Cat.No: TMPH-00294
Species: Bovine
Expression System: P. pastoris (Yeast)
PAG-1 Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00293
Species: Bovine
Expression System: E. coli
HSPB7 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01375
Species: Human
Expression System: E. coli
PSG2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00838
Species: Human
Expression System: HEK293 Cells
PAG-2 Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00295
Species: Bovine
Expression System: E. coli
PSG9 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00522
Species: Human
Expression System: HEK293 Cells
PSG7 Protein, Human, Recombinant (His)
Cat.No: TMPH-01987
Species: Human
Expression System: E. coli
PSG3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01135
Species: Human
Expression System: HEK293 Cells
PSG7 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01986
Species: Human
Expression System: HEK293 Cells
PSG5 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00506
Species: Human
Expression System: HEK293 Cells
PSG6 Protein, Human, Recombinant (His)
Cat.No: TMPY-02891
Species: Human
Expression System: Baculovirus Insect Cells
BMPG Protein, Human, Recombinant (His)
Cat.No: TMPJ-00476
Species: Human
Expression System: HEK293 Cells
PZP Protein, Human, Recombinant (His)
Cat.No: TMPH-01896
Species: Human
Expression System: E. coli
PSG1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00551
Species: Human
Expression System: HEK293 Cells
PSG1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00552
Species: Human
Expression System: HEK293 Cells
Glycodelin Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01402
Species: Human
Expression System: HEK293 Cells
Glycodelin Protein, Human, Recombinant (His)
Cat.No: TMPH-01401
Species: Human
Expression System: E. coli
GSTA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00539
Species: Human
Expression System: HEK293 Cells
AFM Protein, Human, Recombinant (His)
Cat.No: TMPY-03962
Species: Human
Expression System: HEK293 Cells
LAIR2 Protein, Human, Recombinant (Avi & His)
Cat.No: TMPK-00030
Species: Human
Expression System: HEK293 Cells
TAC3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01379
Species: Human
Expression System: E. coli
ADAMDEC1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02493
Species: Mouse
Expression System: E. coli
CRHBP Protein, Human, Recombinant (His)
Cat.No: TMPJ-00906
Species: Human
Expression System: HEK293 Cells
CSH2 Protein, Human, Recombinant (GST & His)
Cat.No: TMPH-01087
Species: Human
Expression System: E. coli
CGB Protein, Human, Recombinant (His)
Cat.No: TMPJ-00049
Species: Human
Expression System: HEK293 Cells
CGB7 Protein, Human, Recombinant (His)
Cat.No: TMPY-02800
Species: Human
Expression System: Baculovirus Insect Cells
ADAMDEC1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00665
Species: Human
Expression System: HEK293 Cells
VLDLR Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00928
Species: Mouse
Expression System: HEK293 Cells
PLGF/PGF Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00987
Species: Mouse
Expression System: HEK293 Cells
AMHRII Protein, Human, Recombinant
Cat.No: TMPK-00976
Species: Human
Expression System: HEK293 Cells
AMHRII Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00977
Species: Human
Expression System: HEK293 Cells
Granzyme D/GZMD Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00832
Species: Mouse
Expression System: HEK293 Cells
ANXA5 Protein
Cat.No: TMPY-00540
Species:
Expression System:
Relaxin 1/RLN1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01826
Species: Human
Expression System: HEK293 Cells
DDR1 Protein, Human, Recombinant (aa 21-417, His)
Cat.No: TMPH-01297
Species: Human
Expression System: HEK293 Cells
CA125/MUC16 Protein, Human, Recombinant (hFc & AVI), Biotinylated
Cat.No: TMPJ-01432
Species: Human
Expression System: HEK293 Cells
CSF1R Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-01418
Species: Cynomolgus
Expression System: HEK293 Cells
CSF1R Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-01419
Species: Cynomolgus
Expression System: HEK293 Cells
PLGF-2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00054
Species: Human
Expression System: HEK293 Cells
Annexin A8 Protein, Human, Recombinant (His)
Cat.No: TMPY-00585
Species: Human
Expression System: E. coli
Cat. No. Product Name Target Signaling Pathways
TMID-0135 Melengestrol acetate-d3

Melengestrol acetate-d3 是 Melengestrol acetate 的氘代化合物。Melengestrol acetate 的 CAS 号为 2919-66-6。Melengestrol acetate 是孕酮的衍生物,充当皮质类固醇激素。 Melengestrol acetate 可以促进月经活动和妊娠维持的子宫内膜增殖延迟。
TMIJ-0280 Estriol-d3

Estriol-d3 是 Estriol 的氘代化合物。Estriol 的 CAS 号为 50-27-1。Estriol 是G蛋白偶联雌激素受体拮抗剂,能够作用于雌激素受体阴性乳腺癌细胞。
TMIJ-0035 16α-Hydroxy-17β-estradiol-2,4-d2

16α-Hydroxy-17β-estradiol-2,4-d2 是 Estriol 的氘代化合物。Estriol 的 CAS 号为 50-27-1。Estriol 是G蛋白偶联雌激素受体拮抗剂,能够作用于雌激素受体阴性乳腺癌细胞。

同位素标记化合物

Melengestrol acetate-d3
Cat.No: TMID-0135
Synonym:
Target:
Estriol-d3
Cat.No: TMIJ-0280
Synonym:
Target:
16α-Hydroxy-17β-estradiol-2,4-d2
Cat.No: TMIJ-0035
Synonym:
Target:
TargetMol Loading
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