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21
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Cat. No. | Product Name | ||
---|---|---|---|
L6140 | 糖类及苷类化合物库 | 595 compounds | |
595 种糖类或苷类的化合物,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T81424 |
Polysaccharidase
Tremella polysaccharide |
Others | Others |
Polysaccharidase (Tremella polysaccharide) 是一种提升免疫功能的真菌多糖。该化合物展现出治疗化疗和放疗导致的白细胞减少症的研究潜力。 | |||
TP2365L |
Acetyl tetrapeptide-9 Acetate
Acetyl tetrapeptide-9 Acetate(928006-50-2 Free base) |
Others | Others |
Acetyl tetrapeptide-9 Acetate 在刺激基底膜多糖(lumican)和胶原蛋白 I 的合成中发挥作用。 | |||
T10110 |
3-CPs
3-Carbethoxypsoralen,3-Ethoxycarbonylpsoralen |
Antibiotic | Microbiology/Virology |
3-CPs (3-Carbethoxypsoralen) 是一种博来霉素诱导的小鼠肺纤维化血清型荚膜多糖,属于补骨脂,可干扰抗体介导的细菌杀伤作用。3-CPs 可延缓博来霉素诱导的小鼠肺纤维化,可用于研究气道炎和哮喘。 | |||
T40626 |
Curdlan
|
Others | Others |
Curdlan 是一种多糖,由细菌产生。 | |||
T6531 |
Heparin sodium salt
肝素钠,Sodium heparinate,Heparin sodium |
Factor Xa; Thrombin; Autophagy | Autophagy; Metabolism; Proteases/Proteasome |
Heparin sodium salt (Sodium heparinate) 是一种抗凝血剂,可以干扰血凝过程中的多个环节。Heparin sodium salt 可以与抗凝血酶 III 可逆结合,加快凝血酶因子 IIa 和 Xa 的失活速度,从而发挥抗凝作用。 | |||
T71881 |
Bromophenol red
|
Others | Others |
Bromophenol red (BPR) is a chemical indicator. It has been shown to bind to lysozymes and inhibits their activity against bacterial cell walls, but not against the polysaccharide component of peptidoglycan. | |||
T38246 |
L-Triguluronic acid
|
Others | Others |
L-Triguluronic acid, a linear polysaccharide copolymer consisting of three L-guluronic acid (G) units, serves as a precursor for Alginate[1]. Alginate, an unbranched polyanionic polysaccharide, has applications in the development of delivery carriers for anti-fungal agents[2]. | |||
T39278 |
L-Pentaguluronic acid
|
Others | Others |
L-Pentaguluronic acid, a linear polysaccharide copolymer, consists predominantly of four units of L-guluronic acid (G). | |||
TP2365 |
Acetyl tetrapeptide-9
LS9745,N-Acetyl-gln-asp-val-his,Dermican,LS-9745,LS 9745 |
||
Acetyl tetrapeptide-9 is important for the stimulation of basement membrane polysaccharide (lumican) and the synthesis of collagen I. | |||
T75673 |
L-Diguluronic acid disodium
|
Others | Others |
L-Diguluronic acid disodium 是由两个 L-Guluronic acid 单元直接连接形成的直链多糖共聚物,主要应用于海藻酸的合成。作为无支链的聚阴离子多糖,它在抗真菌试剂载体的研究中也有其用途。 | |||
T38982 |
L-Tetraguluronic acid
|
Others | Others |
L-Tetraguluronic acid, a linear polysaccharide copolymer, comprises four units of L-guluronic acid (G). | |||
T39279 |
L-Hexaguluronic acid
|
Others | Others |
L-Hexaguluronic acid, a linear polysaccharide copolymer, consists of six units of L-guluronic acid (G). | |||
T37045 |
1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose
|
Others | Others |
1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-mannopyranose is an analog of N-acetylmannosamine (ManNAc) and a building block.1,2It has been used as a precursor in the synthesis of differently substituted trimers of the group AN. meningitidiscapsular polysaccharide repeating unit for use in immunological experiments.2It has also been used in the synthesis of fluorescent probes for lysosomal labeling.3 | |||
T37902 |
Uridine-5'-diphosphoglucuronic Acid (sodium salt hydrate)
|
Others | Others |
Uridine-5'-diphosphoglucuronic acid is a nucleoside diphosphate sugar that is a source of glucuronic acid for polysaccharide biosynthesis. This compound can be used for the formation of many glucuronides with various aglycones.1 1.Green, M.D., and Tephly, T.R.Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteinsDrug Metab. Dispos.26(9)860-867(1998) | |||
T79132 |
Du011
|
Others | Others |
Du011为针对MprA的大肠杆菌多糖胶囊生物发生抑制剂,用于探讨抗大肠杆菌感染的潜能。 | |||
T76755 | Panobacumab | ||
Panobacumab (KBPA101) 是一种完全人 IgM/κ 单克隆抗体,由人类 B 淋巴细胞产生,对血清型 O11P. aeruginosa 的 LPS O 多糖具有抗性。 | |||
T37900 |
UDP-Glucuronic Acid (sodium salt hydrate)
|
Others | Others |
UDP-Glucuronic acid is a nucleoside diphosphate sugar that is a source of glucuronic acid for polysaccharide biosynthesis. This compound can be used for the formation of many glucuronides with various aglycones.1 1.Green, M.D., and Tephly, T.R.Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteinsDrug Metab. Dispos.26(9)860-867(1998) | |||
TNU1050 |
3-Deoxy-1,2;5,6-di-O-isopropylidene-D-glucofuranose
|
Others | Others |
3-Deoxy-1,2;5,6-di-O-isopropylidene-D-glucofuranose 是一种多糖类的低聚糖。它用于糖基化的合成,可以定制合成用作药物中的碳水化合物。它通过抑制病毒蛋白合成而对Epstein-Barr 病毒具有抗病毒活性。 | |||
T83672 |
TTAPE-Me
1,1,2,2-tetrakis[4-(2-Trimethylammonioethoxy)-phenylethene |
||
TTAPE-Me是一种聚集诱导发光(AIE)荧光团。它被用于检测阴离子磷脂,包括心磷脂、磷脂酰甘油(PG)和磷脂酰丝氨酸(PS)、核酸,以及阴离子多糖肝素。 | |||
T78343 |
Driselase
|
Others | Others |
Driselase是一种商业真菌原生质酶制剂,该复合壁消化酶混合物在测试多糖消化方面效率极高,并能显著提高材料的拉伸及压痕顺应性。即便经过6小时的消化作用,Driselase也不会引起壁蠕变现象。 | |||
T75518 |
Galactofucan
|
Others | Others |
Galactofucan (Fucogalactan) 是一种硫酸多糖。Galactofucan 可以从棕色海藻 Saccharina longicruris 中提取,具有抗凝血、抗肿瘤、抗血栓形成、抗炎、抗病毒等特性。Galactofucan 对 HSV-1和 HSV-2具有抗病毒活性,IC50值分别为 0.76 和 1.34 µg/mL 。Galactofucan 可用于癌症和炎症的研究。 | |||
T76585 |
Hepcidin-20 (human)
|
||
Hepcidin-20 (human) 是一种β-折叠结构肽,含有组氨酸和丰富的半胱氨酸,具备抗真菌活性,并能抑制多糖细胞间粘附素 (PIA) 阳性及阴性菌株的生物膜形成及细菌细胞代谢[3]。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7544 |
Fucoidan
岩藻多糖 |
Others | Others |
Fucoidan 是一种 α-淀粉酶和 α-葡萄糖苷酶的有效抑制剂,是一种生物特性多糖。 它具有抗凝血,抗肿瘤,抗氧化和抗脂肪特性。 | |||
T20597 |
Alginic acid
Protanal LF,褐藻酸,Snow acid algin G,Kelacid,Sazzio,Norgine |
Apoptosis; Autophagy; Histamine Receptor | Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Alginic acid (Snow acid algin G) 是一种从褐海藻中提取的天然多糖,具有抗过敏和抗炎活性。 Alginic acid 抑制组胺释放,可用于食品工业。 | |||
T41078 |
Lipopolysaccharides, Escherichiacoli
Lipopolysaccharide, E. coli O111:B4 |
Others | Others |
Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) 是革兰氏阴性细菌细胞壁的一种特有成分,由脂质A、寡糖核心和 O -特异性多糖 (O-antigen) 3个区域组成。Lipopolysaccharides, Escherichiacoli 有利于维持细胞外膜的完整性,保护细菌免受胆汁盐和脂类抗生素的破坏。Lipopolysaccharides, Escherichiacoli 是一种高免疫原性抗原,可以增强免疫反应,可以用于炎症模型构建。 | |||
T11855 |
Lipopolysaccharides
脂多糖,LPS |
Others | Others |
Lipopolysaccharides (LPS) 是革兰氏阴性细菌细胞壁的一种特有成分,由脂质A、寡糖核心和 O -特异性多糖 (O-antigen) 3个区域组成。Lipopolysaccharides 有利于维持细胞外膜的完整性,保护细菌免受胆汁盐和脂类抗生素的破坏。Lipopolysaccharides 是一种高免疫原性抗原,可以增强免疫反应,可以用于炎症模型构建。 | |||
TN6768 |
Amylopectin
|
Others | Others |
Amylopectin 是一种基于葡萄糖的高度支化的多糖。它与直链淀粉一起形成淀粉。支链淀粉的糖苷键为α-葡聚糖链α- 1、4和支链点α- 1,6。 | |||
T22291 |
Chitin
Chitin (From shrimp and crab shells) |
Others | Others |
Chitin 是一种大型的结构多糖,存在于真菌的细胞壁、昆虫的外骨骼以及鱼类和无脊椎动物的某些坚硬结构中。 | |||
T19355 |
Heparan Sulfate
硫酸乙酰肝素,硫酸类肝素 |
FGFR; Wnt/beta-catenin; Endogenous Metabolite | Angiogenesis; Cytoskeletal Signaling; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors |
Heparan sulfate 是一种复杂的线性多糖。Heparan sulfate 作为硫酸乙酰肝素蛋白聚糖的一部分出现,在细胞外基质和细胞表面表达丰富。 | |||
T5733 |
Xylotetraose
|
Others | Others |
Xylotetraose 是木聚糖的水解产物,可用于酶生化分析。Xylan 是由木糖单元组成的多糖,主要包含由纤维素连接的 β-D- 木糖单位。 | |||
T5043 |
Lentinan
|
Others | Others |
Lentinan 是一种 β-葡聚糖,从香菇中提取获得。它在日本已被批准用作胃癌的生物反应调节剂。 | |||
T1715 |
Chitosan (MW 150000)
壳聚糖,Chitosan,Poly(D-glucosamine),Deacetylated chitin |
Antibacterial; Antifungal | Microbiology/Virology |
Chitosan (MW 150000) (Deacetylated chitin) 是衍生自几丁质的聚阳离子线性多糖。它无毒,具有低致敏性,生物相容性和可生物降解性。它还具有抗肿瘤,抗细菌,抗真菌和抗氧化活性。 | |||
T5120 |
Rhamnose
6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose |
Calcium Channel; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism |
alpha-L-Rhamnose (6-Deoxy-L-mannose) 是存在植物和细菌中的一种单糖。Rhamnose- 免疫原连接物能被用于免疫疗法。Rhamnose 能通过胞外途径穿过上皮细胞,能够作为肠吸收的标志。 | |||
T4809 |
Pyrimidine
嘧啶,Metadiazine |
Others; Endogenous Metabolite | Metabolism; Others |
Pyrimidine (Metadiazine) 是内源性代谢产物的一种。 | |||
T21027 |
Guar gum
Guaran,Gum cyamopsis,Gum guar,Guar flour |
Others | Others |
Guar gum is a galactomannan polysaccharide extracted from guar beans, it has stabilizing and thickening properties useful in food, feed, and industrial applications. | |||
T11513 |
Gum arabic
Arabic gum,阿拉伯胶 |
Others | Others |
Gum Arabic, a branched-chain, complex polysaccharide derived from A. Senegal, exhibits antioxidant properties and offers protection against experimental hepatic, renal, and cardiac toxicities. Additionally, it finds application in immunohistochemistry. | |||
T38245 |
L-Diguluronic acid
|
Others | Others |
L-Diguluronic acid, a linear polysaccharide copolymer consisting of two L-guluronic acid (G) units, serves as a precursor for Alginate[1], a categorically unbranched polyanionic polysaccharide. Alginate finds application in the development of antifungal agent delivery carriers[2]. | |||
T72730 |
D-Isofloridoside
|
Others | Others |
D-Isofloridoside 是多糖前体之一,具有清除自由基、抑制ROS 表达、抑制MMP-2和MMP-9的活性。 | |||
T78497 |
λ-Carrageenan
|
Others | Others |
λ-Carrageenan是广泛应用于基础研究的海藻多糖,常用作促炎剂,并具有有效的抗肿瘤活性。 | |||
T82369 |
Fructo-oligosaccharide DP14
|
||
Fructo-oligosaccharide DP14为从Atractylodes lancea中提取的寡糖。 | |||
T82751 |
Celloheptaose
|
||
Celloheptaose为含七个葡萄糖残基的低聚糖,作为多糖单加氧酶(PMOs)的底物,催化形成氧化的纤维素寡糖。 | |||
T40589 |
6-O-β-D-Galactopyranosyl-D-galactose
|
Others | Others |
6-O-beta-D-Galactopyranosyl-D-galactose, a disaccharide, is a constituent of the polysaccharide backbone characterized by beta-(1→6) glycoside linkages, with a side chain attached to the primary chain through a beta-(1→3) bond. | |||
T82750 |
Cellooctaose
|
||
Cellooctaose,由8个葡萄糖残基构成的低聚糖,作为低成本的多糖,在发酵中能促进重组乳酸菌的生长。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03525 |
Cap5A Protein, S. aureus, Recombinant (His)
Capsular polysaccharide type 5 biosynthesis protein... |
Staphylococcus aureus | E. coli |
Required for the biosynthesis of type 5 capsular polysaccharide (Cap5/CP5). Might act as the chain-length regulator. Cap5A Protein, S. aureus, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is P95695. | |||
TMPH-00123 |
Endoglucanase D Protein, Aspergillus kawachii, Recombinant (His & SUMOstar)
eglD,cel61A,AA9 family lytic polysaccharide monooxy... |
Aspergillus kawachii | P. pastoris (Yeast) |
Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates. Endoglucanase D Protein, Aspergillus kawachii, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-sumostar tag. The predicted molecular weight is 55.7 kDa and the accession number is Q96WQ9. | |||
TMPH-00122 |
Endoglucanase D Protein, Aspergillus kawachii, Recombinant (His)
AA9 family lytic polysaccharide monooxygenase A,cel... |
Aspergillus kawachii | E. coli |
Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. Involved in the degradation of complex natural cellulosic substrates. Endoglucanase D Protein, Aspergillus kawachii, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 45.2 kDa and the accession number is Q96WQ9. | |||
TMPH-03327 |
MBL2 Protein, Rat, Recombinant (His)
Mannan-binding protein,Ra-reactive factor polysaccharide... |
Rat | E. coli |
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.0 kDa and the accession num... | |||
TMPH-03569 |
IcaB Protein, S. aureus, Recombinant (His & Myc)
Intercellular adhesion protein B,Poly-beta-1,6-N-acetyl-D-gl... |
Staphylococcus aureus | E. coli |
Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. N-deacetylation is crucial for attachment of the polysaccharide to the bacterial cell surface; it leads to the introduction of positive charges in the otherwise neutral PIA polymer, allowing electrostatic interactions. IcaB Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular ... | |||
TMPH-00712 |
PGAB Protein, E. coli, Recombinant (His & Myc)
Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase,pgaB |
E. coli | E. coli |
Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide. N-deacetylation promotes PGA export through the PgaA porin. PGAB Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 82.6 kDa and the accession number is P75906. | |||
TMPH-01632 |
MRC1 Protein, Human, Recombinant (His)
Human mannose receptor,C-type lectin domain family 13 member... |
Human | E. coli |
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.; (Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens.; (Microbial infection) Acts as a receptor for Dengue virus envelope protein E.; (Microbial infection) Interacts with Hepatitis B virus envelope protein. MRC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 69.9... | |||
TMPJ-00908 |
LMW-PTP Protein, Human, Recombinant (His)
Low Molecular Weight Cytosolic Acid Phosphatase,Adipocyte Ac... |
Human | E. coli |
Low Molecular Weight Phosphotyrosine Protein Phosphatase (LMW-PTP) is a member of the low molecular weight phosphotyrosine protein phosphatase family. LMW-PTP serves as an acid phosphatase and a protein tyrosine phosphatase (PTPase) by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. LMW-PTP can be detected in all human tissues, including adipocytes. LMW-PTP is a cytosolic enzyme that regulate cell proliferation and growth of leiomyomas during dephosphorylation of t... | |||
TMPY-02131 |
Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST)
acid phosphatase 1, soluble,HAAP |
Human | E. coli |
The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of important physiological functions, including stress resistance and synthesis of the polysaccharide capsule. ACP1/LMW-PTP is an enzyme involved in platelet-derived growth factor-induced mitogenesis and cytoskeleton rearrangement. LMW-PTP is able to specifically bind and dephosphoryl... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T69966 |
Roxadustat-d5
|
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Roxadustat-d5 is intended for use as an internal standard for the quantification of roxadustat by GC- or LC-MS. Roxadustat is an inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH; IC50s = 1.4, 1.26, and 1.32 µM for HIF-PH1, HIF-PH2, and HIF-PH3, respectively). It is selective for HIF-PH over other 2-oxoglutarate-dependent dioxygenases, including lysine-specific demethylase 5A (KDM5A), KDM5B, -5C, -5D, and -6B (IC50s = >100 µM for all). Roxadustat (10-200 µM) stabilizes HIF-1α and ... |