mllt1

SGC-iMLLT 是一种选择性的MLLT1 3-组蛋白相互作用抑制剂，IC50值为 0.26 μM，也是化学探针。它对 MLLT1 YEATS 域 (YD) 和 MLLT3 YD (AF9 YEATS3) 具有高结合力，Kd 值分别为 0.129 和 0.077 μM。

PFI-6 is a selective and non-cytotoxic probe targeting the YEATS domain of MLLT1 (ENL YEATS1) and MLLT3 (AF9 YEATS3), with IC50 values of 140 nM for MLLT1 and 160 nM for MLLT3. It serves as a molecular tool to investigate the role of MLLT1 3 in diseases and genome validation studies [1].

NVS-MLLT-1 is a selective inhibitor of YEATS domain of MLLT1 and MLLT3.