mal-amido-peg4-acid

Mal-amido-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- (4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butanoic acid)可用于后续化学的带有烷基接头和末端酸的 Cereblon 配体。

Mal-amido-PEG7-acid (Mal-NH-PEG7-COOH) 是一种基于 PEG 的 PROTAC linker，可用于合成 PROTAC。

Mal-amido-PEG4-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

Thalidomide-O-amido-PEG-C2-NH2 hydrochloride 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker，是一种合成的 E3 连接酶配体-linker 偶联物。它可用于 PROTAC 的合成分子。

Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 的合成分子。

The compound 3,4-Dibromo-Mal-PEG8-acid is a PEG-based PROTAC linker employed for PROTAC synthesis[1].

Boc-NH-C6-amido-C4-acid (PROTAC Linker 32) is an alkyl ether-based linker extensively employed in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Mal-PEG-mal (MW 3400) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-N-bis(PEG4-C2-acid) is a polyethylene glycol (PEG) derivative serving as a PEG-based PROTAC linker for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Mal-amido-PEG10-C2-NHS ester is a noncleavable ADC linker, comprising a maleimide group and an NHS ester, which serves as a labeling agent for primary amines (-NH2) found in proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

Mal-amido-PEG12-NHS ester is a polyethylene glycol (PEG)-derived linker for proteolysis-targeting chimeras (PROTACs)[1]. It is employed in the synthesis of PROTACs, enabling the conjugation of desired target-specific ligands for protein degradation[1].

Mal-amido-PEG6-NHS ester is a polyethylene glycol (PEG)-based linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Mal-amido-PEG3-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG12-TFP ester is a polyethylene glycol (PEG)-based linker utilized for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Ald-Ph-amido-PEG24-acid is a polyethylene glycol (PEG)-based linker used for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Mal-amido-PEG2-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG-mal (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

4-Methyl-4-(methyldisulfanyl)pentanoic acid is an ADC linker employed in the synthesis of antibody-drug conjugates (ADCs) that can be cleaved.

Cbz-N-amido-PEG20-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-Amido-PEG4-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It can be conjugated to Tubulysin and its derivative cytotoxic molecule [1].

HO-PEG-mal (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(m-PEG4)-N'-(4-Hydroxycyclohexyl-1-amido-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker compound primarily utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

m-PEG-mal (MW 30000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG-mal (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-(CH2COOH)2, also known as compound 7a, is an intermediate compound that contains maleimidoethyl for use in hydrophilic ADC linker synthesis[1].

Mal-amido-PEG24-TFP ester is a polyethylene glycol (PEG)-derived linker for PROTAC synthesis[1].

Mal-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG8-NHS ester 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。

4-Boc-amino-22-dimethylbutyric acid is an alkyl ether-derived PROTAC linker, suitable for the synthesis of PROTACs.

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate compound that combines a Thalidomide-based cereblon ligand and a linker, which is commonly utilized in PROTAC technology. This compound acts as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Mal-amido-PEG3-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG8-TFP ester is a polyethylene glycol (PEG) derivative serving as a PEG-based PROTAC linker, specifically utilized in PROTAC synthesis[1].

Mal-amido-PEG10-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG12-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG10-C2-NHS ester is a noncleavable antibody-drug conjugate (ADC) linker that consists of a maleimide group and an N-hydroxysuccinimide (NHS) ester. The NHS ester enables efficient labeling of primary amines (-NH2) in proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

Boc-NH-PEG2-C2-amido-C4-acid (PROTAC Linker 30) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

m-PEG-mal (MW 20000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

4-Bromobutylphosphonic acid is an alkyl chain-derived PROTAC linker employed for the synthesis of PROTACs[1].

4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl ether-based linker, suitable for PROTAC synthesis [1].

Mal-amido-PEG2-NHS ester is a noncleavable linker for antibody-drug conjugates (ADCs) that consists of a maleimide group and an NHS ester. The NHS ester allows for the labeling of protein primary amines (-NH2), amine-modified oligonucleotides, and other amine-containing molecules[1][2].

m-PEG-mal (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker utilized in the synthesis of PROTACs[1].

Mal-PEG5-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.