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Search Results for " human milk "

12

抑制剂 & 化合物

15

天然产物

7

重组蛋白

1

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T76181	Human milk lysozyme
	Human milk lysozyme，一种在人乳中发现的溶菌酶，被认为是保护新生儿胃肠道免受细菌感染的关键防御因子。
T41160	Lalistat 2	Lipase	Metabolism
	Lalistat 2 是一种溶酶体酸性脂肪酶的特异性抑制剂，IC50 为 152 nM，对人胰脂肪酶或牛乳脂蛋白脂肪酶没有抑制作用（高达 10 μM）。
T85225	1,2-Dioleoyl-3-Docosohexaenoyl-rac-glycerol 1,2-Olein-3-Docosohexaenoin,C1OO,TG(18:1/18:1/22:6),18:1/18:1/22:6-TG	Others	Others
	1,2-Dioleoyl-3-docosohexaenoyl-rac-glycerol, a triacylglycerol, consists of oleic acid at the sn-1 and sn-2 positions and docosahexaenoic acid at the sn-3 position. This compound has been identified in human breast milk.
T85241	1-Myristoyl-2-Palmitoyl-3-Butyryl-rac-glycerol 1-Myristin-2-Palmitin-3-Butyrin,14:0/16:0/4:0-TG,TG(14:0/16:0/4:0)	Others	Others
	1-Myristoyl-2-palmitoyl-3-butyryl-rac-glycerol, a triacylglycerol with myristic acid (at the sn-1 position), palmitic acid (at the sn-2 position), and butyric acid (at the sn-3 position), has been detected in human breast milk.
T85132	1,3-Dilinoleoyl-2-Stearoyl Glycerol 18:2/18:0/18:2-TG,1,3-Linolein-2-Stearin,TG(18:2/18:0/18:2)	Others	Others
	1,3-Dilinoleoyl-2-stearoyl glycerol, a triacylglycerol, incorporates linoleic acid at the sn-1 and sn-3 positions and stearic acid at the sn-2 position. This compound is present in soybean oil and both transitional and mature human milk.
T85058	1-Myristoyl-2-Linoleoyl-3-Oleoyl-rac-glycerol TG(14:0/18:2/18:1),1-Myristin-2-Linolein-3-Olein	Others	Others
	1-Myristoyl-2-linoleoyl-3-oleoyl-rac-glycerol, a triacylglycerol, features myristic acid, linoleic acid, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. This compound is prevalent in mature human milk, infant formula fats, and butterfat.
T85282	trans-Petroselinic Acid trans-6-Octadecenoic Acid,Δ6-trans-Octadecenoic Acid,Petroselaidic Acid	Others	Others
	Trans-Petroselinic acid, the trans isomer of petroselinic acid and an isomer of oleic acid, is detected in the milk fat of cows, goats, and ewes, as well as human breast milk. In HepG2 cells, when treated with trans-petroselinic acid (100 μM), there is an increase in the cellular content of triacylglycerols and cholesterol esters. Additionally, it upregulates the transcription of genes associated with fatty acid synthesis (SREBP-1c, ACACA, FASN, SCD1) and cholesterol synthesis (HMGCR, HMGCS1, FD...
T84505	8(Z),14(Z)-Eicosadienoic Acid	Others	Others
	8(Z),14(Z)-Eicosadienoic Acid, an ω-8 C20:2 fatty acid, constitutes 0.19% of total fatty acids in human milk. In vivo, it is converted by desaturases into eicosatrienoic acids, known for their potent vasodilator properties. However, the physiological effects of 8(Z),14(Z)-Eicosadienoic Acid remain unexplored.
T85223	1-Palmitoyl-2-Linoleoyl-3-Stearoyl-rac-glycerol 1-Palmitin-2-Linolein-3-Stearin,16:0/18:2/18:0-TG,TG(16:0/18:2/18:0)	Others	Others
	1-Palmitoyl-2-linoleoyl-3-stearoyl-rac-glycerol, a triacylglycerol, comprises palmitic acid (at the sn-1 position), linoleic acid (at the sn-2 position), and stearic acid (at the sn-3 position). This compound is present in mature human milk and various plant oils.
T38042	Resolvin D4 Resolvin D4,RvD4	Others	Others
	Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid . [1] It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines.[2][3] RvD4, at 10 ng/mouse, reduces neutrophil infiltration in zymosan A-induced peritonitis and, at 200 ng/mouse, diminishes neutrophil infiltration in response to S. aureus infection. [3] With isolated cells, RvD4 promotes phagocytosi...
T37347	6'-Sialyllactose Sodium Salt 6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose	Others	Others
	6'-Sialyllactose consists of the monosaccharide N-acetylneuraminic acid linked to the galactosyl subunit of lactose at the 6 position. This connection is at the 3 position in the related compound, 3’-sialyllactose. Both are major milk oligosaccharides that avidly bind several viral strains, including strains of influenza, HIV-1, reovirus, and polyomavirus.[1],[2],[3],[4],[5],[6] These compounds can be used to differentiate and characterize the binding domains of viruses that recognize N-acetylne...
T35854	9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)	Others	Others
	9(Z),11(E)-Conjugated linoleic acid is an isomer of linoleic acid that has been found in beef and milk fat.1It binds to peroxisome proliferator-activated receptor α (PPARα; IC50= 140 nM) and activates the receptor in a reporter assay using COS-1 cells expressing mouse PPARα when used at a concentration of 100 μM.29(Z),11(E)-Conjugated linoleic acid inhibits TNF-α-inducedGLUT4expression and increases insulin-stimulated glucose transport in 3T3-L1 adipocytes.3Dietary administration of 9(Z)11(E)-co...

化合物

Human milk lysozyme

Cat.No: T76181

Cat.No: T41160

Target: Lipase

1,2-Dioleoyl-3-Docosohexaenoyl-rac-glycerol

Cat.No: T85225

Synonym: 1,2-Olein-3-Docosohexaenoin,C1OO,TG(18:1/18:1/22:6),18:1/18:1/22:6-TG

Target: Others

1-Myristoyl-2-Palmitoyl-3-Butyryl-rac-glycerol

Cat.No: T85241

Synonym: 1-Myristin-2-Palmitin-3-Butyrin,14:0/16:0/4:0-TG,TG(14:0/16:0/4:0)

Target: Others

1,3-Dilinoleoyl-2-Stearoyl Glycerol

Cat.No: T85132

Synonym: 18:2/18:0/18:2-TG,1,3-Linolein-2-Stearin,TG(18:2/18:0/18:2)

Target: Others

1-Myristoyl-2-Linoleoyl-3-Oleoyl-rac-glycerol

Cat.No: T85058

Synonym: TG(14:0/18:2/18:1),1-Myristin-2-Linolein-3-Olein

Target: Others

trans-Petroselinic Acid

Cat.No: T85282

Synonym: trans-6-Octadecenoic Acid,Δ6-trans-Octadecenoic Acid,Petroselaidic Acid

Target: Others

8(Z),14(Z)-Eicosadienoic Acid

Cat.No: T84505

Target: Others

1-Palmitoyl-2-Linoleoyl-3-Stearoyl-rac-glycerol

Cat.No: T85223

Synonym: 1-Palmitin-2-Linolein-3-Stearin,16:0/18:2/18:0-TG,TG(16:0/18:2/18:0)

Target: Others

Cat.No: T38042

Synonym: Resolvin D4,RvD4

Target: Others

6'-Sialyllactose Sodium Salt

Cat.No: T37347

Synonym: 6'-Sialyllactose Sodium Salt,6'-N-Acetylneuraminyl-D-lactose

Target: Others

9(Z),11(E)-Conjugated Linoleic Acid (sodium salt)

Cat.No: T35854

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN6796	2'-FUCOSYLLACTOSE 2'-Fucosyl-D-lactose,2'-岩藻糖基乳糖	Others	Others
	2'-FUCOSYLLACTOSE (2'-Fucosyl-D-lactose) 是一种含岩藻糖的寡糖。
T5223	Heneicosanoic acid 二十一碳酸,Heneicosylic Acid,C21:0	Others; Endogenous Metabolite	Metabolism; Others
	Heneicosanoic acid (C21:0) 是广泛存在于动植物中的长链饱和脂肪酸。
T1660	Silibinin 水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I	Reactive Oxygen Species; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Silibinin (Silybin) 是水飞蓟的主要活性成分，具有抗癌和化疗预防作用，能抑制细胞增殖和迁移。
T5306	H-Abu-OH L-2-氨基丁酸,L-Aminobutyric Acid,L-α-amino-n-Butyric acid,L(+)-2-Aminobutyric acid	Others; Endogenous Metabolite	Metabolism; Others
	H-Abu-OH (L-α-amino-n-Butyric acid) 是氨基丁酸的三个同分异构体之一，它在患有雷氏综合征，同型血尿症，酪氨酸血症，非酮糖症以及鸟氨酸转氨酶症等代谢病儿童的血浆中的含量会明显升高。
T82559	Difucosyllacto-N-neohexaose
	Difucosyllacto-N-neohexaose 是人乳中分离得到的低聚糖。
T83274	6′-Galactosyllactose
	6′-Galactosyllactose是人乳中半乳糖主要的低聚糖成分，它能与3′-Galactosyllactose和4′-Galactosyllactose结合，合成人乳低聚糖和半乳糖人工低聚糖，从而减缓T84、NCM-460和H4细胞以及肠道组织的炎症反应。
T81764	Monofucosyllacto-N-hexaose III MFLNH III
	Monofucosyllacto-N-hexaose III（MFLNH III）是一种具有特定生物学功能的中性人乳寡糖（HMO）。
T81765	Monofucosyllacto-N-hexaose I MFLNH I
	Monofucosyllacto-N-hexaose I (MFLNH I) 作为人乳低聚糖的组分之一, 具有特定的生物学功能。
T81959	Lacto-N-fucopentaose V LNFP V
	Lacto-N-fucopentaose V (LNFP V)为新型五糖，主要存在于人乳及其他生物体液中的低聚糖。
T78481	Lactodifucotetraose 2′,3-Difucosyllactose,Difucosyllactose	Others	Others
	Lactodifucotetraose (Difucosyllactose)，一种四糖，源自人乳。该分子包括D-葡萄糖，D-半乳糖及L-fucose。
T82545	Disialyllacto-N-tetraose
	Disialyllacto-N-tetraose，一种人乳低聚糖，能预防新生大鼠坏死性小肠结肠炎。
T81957	Lacto-N-triose II
	Lacto-N-triose II 作为人乳低聚糖(HMOs)的核心结构单位，具备用于合成复杂HMOs的营养潜力。
T72734	3-Fucosyllactose 3-Fucosyl-D-lactose	Others	Others
	3-Fucosyllactose (3-Fucosyl-D-lactose) 是人类母乳中的主要焦糖之一，具益生元、免疫调节、促进新生儿大脑发育及抗菌功能。
T81960	Lacto-N-difucohexaose II LNDFH II,Lacto-N-fucohexaose
	Lacto-N-difucohexaose II (LNDFH II) 为人乳中的一种重要低聚糖，对婴儿健康具有显著作用。
T81958	Lacto-N-neodifucohexaose II LNnDFH II
	Lacto-N-neodifucohexaose II（Compd 9），一种关键的人乳四糖衍生物，为点击化学反应试剂。该化合物含 Azide 基团，适用于铜催化叠氮-炔环加成反应（CuAAc），与含 Alkyne 基团的分子反应。同时，它也能与含 DBCO 或 BCN 基团的分子，进行菌株促进的炔-叠氮环加成反应（SPAAC）。

天然产物

2'-FUCOSYLLACTOSE

Cat.No: TN6796

Synonym: 2'-Fucosyl-D-lactose,2'-岩藻糖基乳糖

Target: Others

Heneicosanoic acid

Cat.No: T5223

Synonym: 二十一碳酸,Heneicosylic Acid,C21:0

Target: Others, Endogenous Metabolite

Cat.No: T1660

Synonym: 水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I

Target: Reactive Oxygen Species, Autophagy

Cat.No: T5306

Synonym: L-2-氨基丁酸,L-Aminobutyric Acid,L-α-amino-n-Butyric acid,L(+)-2-Aminobutyric acid

Target: Others, Endogenous Metabolite

Difucosyllacto-N-neohexaose

Cat.No: T82559

6′-Galactosyllactose

Cat.No: T83274

Monofucosyllacto-N-hexaose III

Cat.No: T81764

Synonym: MFLNH III

Monofucosyllacto-N-hexaose I

Cat.No: T81765

Synonym: MFLNH I

Lacto-N-fucopentaose V

Cat.No: T81959

Synonym: LNFP V

Lactodifucotetraose

Cat.No: T78481

Synonym: 2′,3-Difucosyllactose,Difucosyllactose

Target: Others

Disialyllacto-N-tetraose

Cat.No: T82545

Lacto-N-triose II

Cat.No: T81957

3-Fucosyllactose

Cat.No: T72734

Synonym: 3-Fucosyl-D-lactose

Target: Others

Lacto-N-difucohexaose II

Cat.No: T81960

Synonym: LNDFH II,Lacto-N-fucohexaose

Lacto-N-neodifucohexaose II

Cat.No: T81958

Synonym: LNnDFH II

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-03182	PLRP2 Protein, Human, Recombinant (His) PLRP2,pancreatic lipase-related protein 2	Human	Baculovirus Insect Cells
	Galactolipase, also known as PNLIPRP2, is a lipase with broad substrate specificity. It can hydrolyze both phospholipids and galactolipids. Galactolipase acts preferentially on monoglycerides, phospholipids and galactolipids. It also hydrolyses milk fat with a lower catalytic efficiency. The expressed galactolipase shows a lipolytic activity that is, however, only marginally dependent on the presence of colipase. The lipolytic activity of pancreatic extracts and human pancreatic juice on Labraso...
TMPJ-01199	BTN2A1 Protein, Human, Recombinant (His) BT2.1,BTN2A1,Butyrophilin subfamily 2 member A1,BTF1	Human	HEK293 Cells
	Butyrophilin 2A1 (BTN2A1) is an approximately widely expressed and variably glycosylated type I transmembrane glycoprotein. Mature human Butyrophilin 2A1 consisits of a 220 amino acid (aa) extracellular domain with two immunoglobulin-like domains, a 21 aa transmembrane segment, and a 258 aa cytoplasmic domain. Alternative splicing generates additional isoforms of human Butyrophilin 2A1 that lack the first Ig like domain or transmembrane segment as well as isoforms with substitutions and deletion...
TMPY-02464	Catalase/CAT Protein, Human, Recombinant (His) catalase	Human	Baculovirus Insect Cells
	Catalase is a ubiquitously expressed enzyme that catalyzes the decomposition of hydrogen peroxide to water and oxygen. It is a tetramer of four polypeptides chains containing four porphyrin heme groups that allow the enzyme to react with the hydrogen peroxide. The optimum PH of human catalase is approximately 7 and the optimum temperature is at 37 degree. Both the PH optimum and temperature for other catalases varies depending on the species. Catalase can be inhibited by a flux of O2-generated i...
TMPK-01534	Chimeric HLA-A02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human*&Mouse, MHC (His & Avi) RING12,PSMB9,Proteasome chain 7,RMF,LMP-2,LMP2,MHC,Macropain...	Human & Mouse	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01523	Chimeric HLA-A02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human*&Mouse, MHC (His & Avi) WAGR,WT33,AWT1,GUD,RMF,WT1,WIT-2,MHC,NPHS4GUD	Human & Mouse	HEK293 Cells
	The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1.
TMPK-01535	Chimeric HLA-A02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human*&Mouse, MHC (His & Avi) Macropain chain 7,LMP2,Proteasome chain 7,RING12,PSMB9,MHC,R...	Human & Mouse	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01522	Chimeric HLA-A02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human*&Mouse, MHC (His & Avi) RMF,WT33,WIT-2,MHC,WAGR,AWT1,GUD,WT1,NPHS4GUD	Human & Mouse	HEK293 Cells
	The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1.

重组蛋白

PLRP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03182

Species: Human

Expression System: Baculovirus Insect Cells

BTN2A1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01199

Species: Human

Expression System: HEK293 Cells

Catalase/CAT Protein, Human, Recombinant (His)

Cat.No: TMPY-02464

Species: Human

Expression System: Baculovirus Insect Cells

Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)

Cat.No: TMPK-01534

Species: Human & Mouse

Expression System: HEK293 Cells

Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)

Cat.No: TMPK-01523

Species: Human & Mouse

Expression System: HEK293 Cells

Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)

Cat.No: TMPK-01535

Species: Human & Mouse

Expression System: HEK293 Cells

Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)

Cat.No: TMPK-01522

Species: Human & Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIH-0521	Silibinin-d3
	Silibinin-d3 是 Silibinin 的氘代化合物。Silibinin 的 CAS 号为 22888-70-6。Silibinin 是水飞蓟的主要活性成分，具有抗癌和化疗预防作用，能抑制细胞增殖和迁移。

同位素标记化合物

Cat.No: TMIH-0521

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