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Cat. No. | Product Name | ||
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L1600 | 激酶抑制剂库 | 2720 compounds | |
2720 种激酶抑制剂/调节剂的独特集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T18949 |
CY5-SE
Cy5 NHS Ester,Sulfo-Cyanine5 Succinimidyl Ester,CY5-NHS酯 |
Others | Others |
CY5-SE (Sulfo-Cyanine5 Succinimidyl Ester) 是一种反应染料 (λex=649 nm,λem=670 nm),可用于标记肽、蛋白质、寡核苷酸的氨基基团。 | |||
T8836 |
CY5-SE triethylamine salt
Fluorolink Cy5 triethanolamine salt,Cy5-SE (triethylamine salt) |
Others | Others |
CY5-SE triethylamine salt (Fluorolink Cy5 triethanolamine salt) 是一种用于标记肽, 蛋白质, 寡核苷酸的氨基基团的反应染料 (Ex=649 nm; Em=670 nm)。 | |||
T19030 |
NBD-Cl
4-氯-7-硝基苯并-2-氧杂-1,3-二唑,NBD chloride |
Others | Others |
NBD-Cl (NBD chloride) 是非荧光剂,能够与巯基或氨基反应,产生高度荧光。 | |||
T14250 |
Amino-PEG8-amine
|
Others | Others |
Amino-PEG8-amine 是一种以聚乙二醇为基础的 PROTAC 连接剂,可用于PROTACs 的合成,是一种含有两个氨基(NH2)基团的共轭PEG 衍生物。 | |||
T15025 |
CY5
Sulfo-Cyanine5 |
Others | Others |
Cy5 (Sulfo-Cyanine5) 是一种花菁类染料,用于标记肽、蛋白质和寡核苷酸中的氨基。 | |||
T18946 |
Cy3 NHS ester
Cyanine3 NHS ester |
Others | Others |
Cy3 NHS ester (Cyanine3 NHS ester) 是一种荧光染料,用于标记蛋白质、肽、抗体和寡核苷酸中的氨基。 | |||
T18949L |
CY5-SE Ditriethylamine salt
CY5-SE Ditriethylamine salt(146368-14-1 Free base) |
Others | Others |
CY5-SE Ditriethylamine salt 是用于标记寡核苷酸,肽,蛋白质的氨基基团的反应染料。 激发波长 (nm): 649, 发射波长 (nm): 670 | |||
T18967 |
Dansyl chloride
丹酰氯,丹磺酰氯,DNSCl |
Others | Others |
Dansyl chloride (DNSC-l) 是一种能够在脂族和芳族胺与伯氨基反应,并产生稳定蓝色或蓝绿色荧光磺酰胺加合物的试剂,广泛用于修饰氨基酸、蛋白质测序和氨基酸分析。 | |||
T38432 |
Cyanine5 NHS ester chloride
|
Others | Others |
Cyanine5 NHS ester chloride 是一种具有红色荧光的活性染料,需要少量的有机共溶剂(如DMF 或DMSO)用于标记肽、蛋白质和寡核苷酸中的氨基。 | |||
T4585 |
EGTA
Ethylenebis(oxyethylenenitrilo)tetraacet,乙二醇双(2-氨基乙基醚)四乙酸 |
Others | Others |
Ethylenebis(oxyethylenenitrilo)tetraacet 是一种特殊的钙离子螯合剂,能够显著抑制炎性巨噬细胞的底物粘附能力。EGTA (Ethylenebis(oxyethylenenitrilo)tetraacet) 在生理 pH 值(7.4) 下,Kd 为 60.5 nM,对 Ca2+比对 Mg2+有很高的特异性。 | |||
T31863 |
FOX-7
DADNE,UNII-3B2KYV7C3F |
Others | Others |
Fox-7 or 1,1-diamino-2, 2-Dinitroethene (DADNE) Fox-7 is similar to the insensitive compound TATB, which is a benzene ring compound with three amino groups and three nitro groups and is an insensitive high-explosive compound. | |||
T24516 |
N-(Amino-PEG1)-N-bis(PEG2-propargyl)
N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt |
Others | Others |
N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt is a PEG derivative containing an amino group with two propargyl groups. PEG Linkers may be useful in the development of antibody-drug conjugates. | |||
T71920 |
9-(Boc-amino)nonanoic Acid
|
Others | Others |
9-(Boc-amino)nonanoic Acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | |||
T18947 |
Cy5.5-SE
|
Others | Others |
Cy5.5-SE is a cyanine dye, labeling amino-groups in oligonucleotides, peptides, and proteins. | |||
T71923 |
EEDQ
|
Others | Others |
EEDQ is an irreversible dopamine-receptor antagonist.EEDQ is also a highly specific reagent for carboxyl groups. It enables the coupling of acylamino acids with amino acid esters in high yield and without racemization. | |||
T18950 |
CY5-YNE
Sulfo-Cyanine5-alkyne |
Others | Others |
CY5-YNE (Sulfo-Cyanine5-alkyne) is a reactive dye for the labeling of amino-groups in oligonucleotides, peptides, and proteins. | |||
T18938 |
Cy2 (iodine)
|
Others | Others |
Cy2 is a cyanine dye used for labeling amino-groups in oligonucleotides, peptides, and proteins (λ excitation: 488 nm; λ emission: 520 nm). | |||
T19943 |
SMPB Crosslinker
SMPB Cross linker,SMPB Cross-linker |
Others | Others |
SMPB crosslinker is a heterobifunctional protein crosslinking reagent that is reactive toward sulfhydryl and amino groups. The SMPB protein crosslinker is an extended chain length analog of MBS crosslinker. SMPB crosslinker's spacer arm is non-cleavable. | |||
T27974 |
Maleimide-PEG4-NHS
MAL-PEG-NHS,Maleimide PEG NHS,Maleimido-Tetra(Ethylene Glycol)-Acetic Acid NHS ester,MAL-PEG4-NHS |
Others | Others |
Maleimide-PEG4-NHS is a sulfhydryl and amine reactive heterofuncational PEG linker. The chemical bonds formed through Maleimide-PEG4-NHS linker are stable and are not cleavable. The NHS ester reacts with amino groups at pH 7-9 to form stable amide bond wh | |||
T70057 |
14-(Fmoc-amino)-tetradecanoic acid
|
Others | Others |
14-(Fmoc-amino)-tetradecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. 14-(Fmoc-amino)-tetradecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | |||
T18939 |
Cy2-SE (iodine)
CY2-SE,Cyanine2 Succinimidyl Ester |
Others | Others |
CY2-SE (Cyanine2 Succinimidyl Ester) is a dye for the labeling of amino-groups in oligonucleotides, peptides, and proteins (Excitation:492 nm, Emission: 510 nm). | |||
T78405 |
Cyanine5 NHS ester iodide
|
||
Cyanine5 NHS ester iodide,一种红色荧光染料,专用于肽、蛋白质与寡核苷酸的氨基标记。 | |||
T71906 |
Boc-12-Ado-OH
|
Others | Others |
Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | |||
T18943 |
CY3-SE
Sulfo-Cyanine3 Succinimidyl Ester,Cy3 NHS Ester |
Others | Others |
CY3-SE (Sulfo-Cy3 NHS ester) is a reactive dye for the labeling of amino-groups in the soluble proteins, peptides, and oligonucleotides/DNA (Excitation: 555 nm, Emission: 570 nm). | |||
T71970 |
Fmoc-7-amino-heptanoic acid
|
Others | Others |
Fmoc-7-amino-heptanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | |||
T71789 |
Boc-7-Aminoheptanoic acid
|
Others | Others |
Boc-7-Aminoheptanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applicaitons. Boc-7-Aminoheptanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | |||
T70303 |
N-Boc-15-aminopentadecanoic acid
|
Others | Others |
N-Boc-15-aminopentadecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | |||
T71872 |
Boc-8-aoc-oh
|
Others | Others |
Boc-8-aoc-oh can be used as a PROTAC linker in the synthesis of PROTACs. Boc-8-aoc-oh is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | |||
T71919 |
Boc-10-Aminodecanoic acid
|
Others | Others |
Boc-10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine. | |||
T83409 |
2,3-Diaminophenazine
2,3-Phenazinediamine |
||
2,3-Diaminophenazine (2,3-Phenazinediamine),一种吩嗪的氨基化合物,广泛用于发光、电化学和生物化学领域的应用。 | |||
T77087 | Mipeginterferon alfa-2b | ||
Mipeginterferon alfa-2b 是一种干扰素IFNA2b 类似物。包括一个 N 末端和 10 个赖氨酸 N6 在内的 11 个氨基,平均被取代掉 5 个。Mipeginterferon alfa-2b 的相对分子质量为 40 kDa。 | |||
T18940 |
Cy2
CY2 Non-Sulfonated,Cyanine2 |
Others | Others |
Cy2 (CY2 Non-Sulfonated)是一种花青染料,波长长,吸收和发射可调,消光系数高,水溶性好。 Cy2 可用于标记寡核苷酸、肽和蛋白质中的氨基。 | |||
T82647 |
Cyanine5 NHS ester bromide
|
||
Cyanine5 NHS ester bromide 是用于标记肽、蛋白质和寡核苷酸氨基的活性染料。作为菁染料,该化合物特别适用于通过精氨酸残基对神经紧张素 (8-13) 进行荧光标记。 | |||
T74987 |
TAMRA alkyne, 6-isomer
|
Others | Others |
TAMRA alkyne, 6-isomer,作为TAMRA的一种连接物,其中TAMRA为发射橙色光的黄蒽类染料,广泛应用于寡核苷酸标记和氨基酸序列分析。此化合物通过引入炔基,实现了与叠氮化合物进行铜催化的点击化学反应的能力。 | |||
T28464 |
p-SCN-Bn-TCMC HCl
p-SCN-Bn-TCMC |
Others | Others |
p-SCN-Bn-TCMC is a bifunctional chelator, it contains a powerful chelator TCMC and reactive tioisocyante linker. TCMC is a powerful chelator with capability to strongly bind radio-isotopic heavy metal ion, which are widely used for radio-diagnostic/imagin | |||
T82903 |
Bdp tr nhs ester
|
||
Bdp tr nhs ester 是一种具有长激发态寿命的化学发光偶联物,适用于免疫测定及显微镜和荧光偏振分析。该NHS ester 在中性或弱碱性环境中能特异性地与伯胺(如赖氨酸残基侧链)或氨基硅烷涂层表面发生反应,形成稳定的共价键。 | |||
T73805 |
Acetyl coenzyme A
|
Others | Others |
Acetyl-coenzyme A (Acetyl-CoA) 是一种具有膜非渗透性的中枢代谢中间体,参与 TCA 循环和氧化磷酸化代谢过程。Acetyl-coenzyme A 通过向目标氨基酸残基提供乙酰基团,来完成蛋白质的翻译后乙酰化反应,从而调节各种细胞机制。Acetyl Coenzyme A 也是脂质合成的关键前体。 | |||
T76008 |
Protein Kinase C (19-31) (TFA)
|
||
Protein Kinase C (19-31) TFA 是蛋白激酶 C (PKC)的抑制剂,是由 PKCa (残基 19-31) 伪底物调控域衍生而来,25 位丝氨酸取代野生型丙氨酸作为蛋白激酶 C 底物肽,用于检测蛋白激酶 C 的活性。Protein kinase C (PKC) TFA 通过磷酸化丝氨酸和苏氨酸氨基酸残基上的羟基来调控其它蛋白的功能。 | |||
T36508 |
trans-4,5-epoxy-2(E)-Decenal
trans-4,5-epoxy-2(E)-Decenal,3-(3-pentyloxiranyl)-2E-propenal |
Others | Others |
Polyunsaturated fatty acids such as arachidonate and linoeate, while essential to health maintenance, are subject to random peroxidation by ambient oxygen, resulting in fragmented and reactive decomposition products. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. One prominent autoxidation product of either trilinolein or arachidonic acid is trans-4,5-epoxy-2(E)-decenal. This aldehyde is responsible for a pungent metallic flavor of d... | |||
T83664 |
Europium W1024 ITC
Eu-W1024 ITC,Europium W1024 Isothiocyanate |
||
Europium W1024 isothiocyanate (ITC) 是一种基于镧系元素的荧光团,具有长发射寿命和大的斯托克斯位移。其激发/发射峰值分别为340/613 nm。Europium W1024 ITC含有一个反应性的异硫氰酸酯基团,能在碱性pH条件下与初级氨基发生反应。在高温、高EDTA浓度或低pH环境下稳定,但在锰的存在下不稳定。Europium W1024 ITC通常被连接到各种分子上,并作为TR-FRET中的供体荧光团使用,其长发射寿命为受体荧光的测量提供了更长的时间窗口,减少了自发荧光的干扰。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5569 |
3-Amino-4-methylpentanoic acid
DL-Homovaline,3-氨基-4-甲基戊酸,DL-beta-leucine,beta-Aminoisocaproic acid,beta-Leucine |
Endogenous Metabolite | Metabolism |
3-Amino-4-methylpentanoic acid (DL-Homovaline) 是 L-亮氨酸的异构体,是 β 氨基酸,通过亮氨酸 2,3-氨基变位酶在人体中由 L-亮氨酸代谢天然产生。 | |||
T4728 |
4-Acetamidobutanoic acid
N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID,4-乙酰氨基丁酸 |
GABA Receptor; Endogenous Metabolite; Antibacterial | Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience |
4-Acetamidobutanoic acid (4-ACETAMIDOBUTYRIC ACID) 可在血液、粪便和尿液以及人体前列腺组织中找到,也存在于从酵母到人类的所有真核生物中。它是GABA 衍生物,具有抗氧化和抗菌活性。 | |||
T4909 |
N-Acetyl-DL-methionine
N-乙酰-DL-蛋氨酸,N-乙酰-DL-甲硫氨酸 |
Others; Endogenous Metabolite | Metabolism; Others |
N-Acetyl-DL-methionine 是内源性代谢产物的一种。 | |||
T19117 |
3-Deoxyglucosone
3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose |
GPX; Glucagon Receptor | GPCR/G Protein; oxidation-reduction |
3-Deoxyglucosone(3-Deoxy-D-glucosone) 是美拉德反应和多元醇反应的中间体途径合成。3-Deoxyglucosone 与蛋白质氨基快速反应形成晚期糖基化末端蛋白 (AGEs)。3-Deoxyglucosone 可使谷胱甘肽过氧化物酶失活,可与低葡萄糖协同作用以增强 GLP-1 分泌,可以作为糖尿病生物学检测的标志物。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02621 |
DAO Protein, Mouse, Recombinant (His)
DAMOX,Dao1,DAO,DAAO,D-amino-acid oxidase |
Mouse | E. coli |
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system... | |||
TMPH-03276 |
DAO Protein, Rat, Recombinant (His & Myc)
D-amino-acid oxidase,Dao1,DAMOX,DAO,DAAO |
Rat | E. coli |
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression sy... | |||
TMPJ-00853 |
DAO Protein, Human, Recombinant (His)
D-Amino-Acid Oxidase,DAMOX,DAAO,DAO |
Human | E. coli |
D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. D-amino-acid oxidase regulates the level of the neuromodulator D-serine in the brain, has a high activity towards D-DOPA and contributes to dopamine synthesis. D-amino-acid oxidase could act as a detoxifying agent which removes D-amino acids accumulated during aging. It also a... | |||
TMPJ-01256 |
Caspase-10 Protein, Human, Recombinant (His)
CASP10,FAS-Associated Death Domain Protein Interleukin-1B-Co... |
Human | E. coli |
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human ca... | |||
TMPY-02516 |
Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)
interferon, α10,interferon, alpha 10,IFN-alphaC,MGC119879,干扰... |
Human | HEK293 Cells |
Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogen... |